| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Edyta Paczkowska, Karolina Łuczkowska, Katarzyna Piecyk, Dorota Rogińska, Ewa Pius-Sadowska, Przemysław Ustianowski, Elżbieta Cecerska, Barbara Dołęgowska, Zbigniew Celewicz, Bogusław Machalińsk. The influence of BDNF on human umbilical cord blood stem/progenitor cells: implications for stem cell-based therapy of neurodegenerative disorders. Acta neurobiologiae experimentalis. vol 75. issue 2. 2016-12-13. PMID:26232994. |
next, after bdnf pre-treatment, lin- cells were extensively assessed with respect to apoptosis using western blotting and proliferation via brdu incorporation. |
2016-12-13 |
2023-08-13 |
human |
| Edyta Paczkowska, Karolina Łuczkowska, Katarzyna Piecyk, Dorota Rogińska, Ewa Pius-Sadowska, Przemysław Ustianowski, Elżbieta Cecerska, Barbara Dołęgowska, Zbigniew Celewicz, Bogusław Machalińsk. The influence of BDNF on human umbilical cord blood stem/progenitor cells: implications for stem cell-based therapy of neurodegenerative disorders. Acta neurobiologiae experimentalis. vol 75. issue 2. 2016-12-13. PMID:26232994. |
bdnf pre-treatment diminished apoptosis in lin- cells and influenced the proliferation of these cells. |
2016-12-13 |
2023-08-13 |
human |
| Shotaro Otsuka, Harutoshi Sakakima, Megumi Sumizono, Seiya Takada, Takuto Terashi, Yoshihiro Yoshid. The neuroprotective effects of preconditioning exercise on brain damage and neurotrophic factors after focal brain ischemia in rats. Behavioural brain research. vol 303. 2016-12-13. PMID:26808606. |
our findings suggest that preconditioning exercise reduced the infract volume and ameliorated motor function, enhanced expression levels of mk and bdnf, increased astrocyte proliferation, increased angiogenesis, and reduced neuronal apoptosis and oxidative stress. |
2016-12-13 |
2023-08-13 |
rat |
| You-Cui Wang, Guo-Ying Feng, Qing-Jie Xia, Yue Hu, Yang Xu, Liu-Lin Xiong, Zhi-Wei Chen, Hang-Ping Wang, Ting-Hua Wang, Xue Zho. Knockdown of α-synuclein in cerebral cortex improves neural behavior associated with apoptotic inhibition and neurotrophin expression in spinal cord transected rats. Apoptosis : an international journal on programmed cell death. vol 21. issue 4. 2016-12-13. PMID:26822976. |
together, endogenous snca play a crucial role in motor and sensory function regulation, in which, the underlying mechanism may be linked to the regulation of apoptosis associated with apoptotic gene (bax, bcl2) and neurotrophic factors expression (ngf, bdnf and nt3). |
2016-12-13 |
2023-08-13 |
rat |
| Yu Gao, Ming Jing, Rongrong Ge, Lili Lan. Induction of hypoxia-inducible factor-1α by BDNF protects retinoblastoma cells against chemotherapy-induced apoptosis. Molecular and cellular biochemistry. vol 414. issue 1-2. 2016-12-13. PMID:26868822. |
induction of hypoxia-inducible factor-1α by bdnf protects retinoblastoma cells against chemotherapy-induced apoptosis. |
2016-12-13 |
2023-08-13 |
human |
| Yu Gao, Ming Jing, Rongrong Ge, Lili Lan. Induction of hypoxia-inducible factor-1α by BDNF protects retinoblastoma cells against chemotherapy-induced apoptosis. Molecular and cellular biochemistry. vol 414. issue 1-2. 2016-12-13. PMID:26868822. |
the results showed that bdnf could induce higher expression of hif-1α via activation of trkb in human y-79 retinoblastoma cells, which consequently contributed to its effect against chemotherapeutic agent-induced cytotoxicity and cell apoptosis. |
2016-12-13 |
2023-08-13 |
human |
| Shamayra Smail, Dalbir Bahga, Brittnee McDole, Kathleen Guthri. Increased Olfactory Bulb BDNF Expression Does Not Rescue Deficits in Olfactory Neurogenesis in the Huntington's Disease R6/2 Mouse. Chemical senses. vol 41. issue 3. 2016-11-02. PMID:26783111. |
although we detected a decline in apoptosis, increased bdnf was not sufficient to normalize granule cell survival within their normal target in r6/2 mice. |
2016-11-02 |
2023-08-13 |
mouse |
| Juan Tang, Xing-ting Zheng, Ke Xiao, Kun-lun Wang, Jing Wang, Yun-xiao Wang, Ke Wang, Wei Wang, Shun Lu, Ke-li Yang, Peng-Peng Sun, Haseeb Khaliq, Juming Zhong, Ke-Mei Pen. Effect of Boric Acid Supplementation on the Expression of BDNF in African Ostrich Chick Brain. Biological trace element research. vol 170. issue 1. 2016-10-28. PMID:26226831. |
adversely, when boric acid doses were higher than 320 mg/l(groups v, vi), the high-dose boric acid neuron structure was damaged with less neurites, particularly at 640 mg/l; (2) the quantity of bdnf expression in groups ii, iii, and iv was increased while it was decreased in groups v and vi when compared with that in group i; (3) tunel reaction and the caspase-3 mrna level showed that the amount of cell apoptosis in group ii, group iii, and group iv were decreased, but increased in group v and group vi significantly. |
2016-10-28 |
2023-08-13 |
chicken |
| Juan Tang, Xing-ting Zheng, Ke Xiao, Kun-lun Wang, Jing Wang, Yun-xiao Wang, Ke Wang, Wei Wang, Shun Lu, Ke-li Yang, Peng-Peng Sun, Haseeb Khaliq, Juming Zhong, Ke-Mei Pen. Effect of Boric Acid Supplementation on the Expression of BDNF in African Ostrich Chick Brain. Biological trace element research. vol 170. issue 1. 2016-10-28. PMID:26226831. |
these results indicated that appropriate supplementation of boric acid, especially at 160 mg/l, could promote ostrich chicks' brain development by promoting the bdnf expression and reducing cell apoptosis. |
2016-10-28 |
2023-08-13 |
chicken |
| Juan Tang, Xing-ting Zheng, Ke Xiao, Kun-lun Wang, Jing Wang, Yun-xiao Wang, Ke Wang, Wei Wang, Shun Lu, Ke-li Yang, Peng-Peng Sun, Haseeb Khaliq, Juming Zhong, Ke-Mei Pen. Effect of Boric Acid Supplementation on the Expression of BDNF in African Ostrich Chick Brain. Biological trace element research. vol 170. issue 1. 2016-10-28. PMID:26226831. |
conversely, high dose of boric acid particularly in 640 mg/l would damage the neuron structure of ostrich chick brain by inhibiting the bdnf expression and increasing cell apoptosis. |
2016-10-28 |
2023-08-13 |
chicken |
| S Streiter, B Fisch, B Sabbah, A Ao, R Abi. The importance of neuronal growth factors in the ovary. Molecular human reproduction. vol 22. issue 1. 2016-10-05. PMID:26487421. |
additionally, ngf, nt3 and gdnf promoted follicular cell proliferation; ngf, bdnf and vip were shown to be involved in ovulation; vip inhibited follicular apoptosis; nt4/5, bdnf and gdnf promoted oocyte maturation and ngf, nt3 and vip stimulated steroidogenesis. |
2016-10-05 |
2023-08-13 |
mouse |
| Jiaming Liu, Jing Sun, Fangyan Wang, Xichong Yu, Zongxin Ling, Haixiao Li, Huiqing Zhang, Jiangtao Jin, Wenqian Chen, Mengqi Pang, Junjie Yu, Yiwen He, Jiru X. Neuroprotective Effects of Clostridium butyricum against Vascular Dementia in Mice via Metabolic Butyrate. BioMed research international. vol 2015. 2016-09-28. PMID:26523278. |
c. butyricum not only increased the levels of bdnf and bcl-2 and decreased level of bax but also induced akt phosphorylation (p-akt) and ultimately reduced neuronal apoptosis. |
2016-09-28 |
2023-08-13 |
mouse |
| Qian Ma, Jianmin Yang, Thomas Li, Teresa A Milner, Barbara L Hempstea. Selective reduction of striatal mature BDNF without induction of proBDNF in the zQ175 mouse model of Huntington's disease. Neurobiology of disease. vol 82. 2016-08-24. PMID:26282324. |
probdnf, the precursor of mature bdnf (mbdnf), also can be secreted but promotes apoptosis of neurons expressing p75(ntr) and sortilin receptors. |
2016-08-24 |
2023-08-13 |
mouse |
| Zhi-wei Yang, Fei Wu, Sheng-Li Zhan. Effects of ganoderic acids on epileptiform discharge hippocampal neurons: insights from alterations of BDNF,TRPC3 and apoptosis. Die Pharmazie. vol 71. issue 6. 2016-08-17. PMID:27455554. |
effects of ganoderic acids on epileptiform discharge hippocampal neurons: insights from alterations of bdnf,trpc3 and apoptosis. |
2016-08-17 |
2023-08-13 |
rat |
| Zhi-wei Yang, Fei Wu, Sheng-Li Zhan. Effects of ganoderic acids on epileptiform discharge hippocampal neurons: insights from alterations of BDNF,TRPC3 and apoptosis. Die Pharmazie. vol 71. issue 6. 2016-08-17. PMID:27455554. |
the apoptosis rate of neurons was inversely proportional to bdnf and trpc3 changes (p < 0.01). |
2016-08-17 |
2023-08-13 |
rat |
| Ping Ma, Xiao-Yuan Mao, Xiao-Lei Li, Ying Ma, Yuan-Dong Qiao, Zhao-Qian Liu, Hong-Hao Zhou, Yong-Gang Ca. Baicalin alleviates diabetes‑associated cognitive deficits via modulation of mitogen-activated protein kinase signaling, brain‑derived neurotrophic factor and apoptosis. Molecular medicine reports. vol 12. issue 4. 2016-07-21. PMID:26300488. |
the findings suggested that baicalin exerts neuroprotective effects against dacd via modulation of mapk cascades, bdnf and apoptosis. |
2016-07-21 |
2023-08-13 |
rat |
| Juhyun Song, So Yeong Cheon, Won Taek Lee, Kyung Ah Park, Jong Eun Le. PKA Inhibitor H89 (N-[2-p-bromocinnamylamino-ethyl]-5-isoquinolinesulfonamide) Attenuates Synaptic Dysfunction and Neuronal Cell Death following Ischemic Injury. Neural plasticity. vol 2015. 2016-07-19. PMID:26448879. |
next, we examined the role of h89 pretreatment on the expression of brain-derived neurotrophic factor (bdnf), psd95, map2, and the apoptosis regulators bcl2 and cleaved caspase-3 in cultured neuroblastoma cells exposed to hypoxia and reperfusion injury. |
2016-07-19 |
2023-08-13 |
mouse |
| Liguo Yang, Shigang Song, Hang L. MicroRNA-322 protects hypoxia-induced apoptosis in cardiomyocytes via BDNF gene. American journal of translational research. vol 8. issue 6. 2016-07-11. PMID:27398164. |
microrna-322 protects hypoxia-induced apoptosis in cardiomyocytes via bdnf gene. |
2016-07-11 |
2023-08-13 |
Not clear |
| Yong Zhang, Rui Lan, Jun Wang, Xiang-Yun Li, Deng-Na Zhu, Yun-Zhi Ma, Ji-Tao Wu, Zhen-Huan Li. Acupuncture reduced apoptosis and up-regulated BDNF and GDNF expression in hippocampus following hypoxia-ischemia in neonatal rats. Journal of ethnopharmacology. vol 172. 2016-06-03. PMID:26116163. |
acupuncture reduced apoptosis and up-regulated bdnf and gdnf expression in hippocampus following hypoxia-ischemia in neonatal rats. |
2016-06-03 |
2023-08-13 |
rat |
| Peifang Jiang, Tao Zhu, Zhezhi Xia, Feng Gao, Weizhong Gu, Xi Chen, Tianming Yuan, Huimin Y. Inhibition of MAPK/ERK signaling blocks hippocampal neurogenesis and impairs cognitive performance in prenatally infected neonatal rats. European archives of psychiatry and clinical neuroscience. vol 265. issue 6. 2016-06-01. PMID:25721317. |
furthermore, inhibition of mapk/erk signaling could aggravate hippocampal neuronal apoptosis, decrease neurogenesis, and impair the offspring's cognitive performances and could also down-regulate the levels of p-erk, p-creb and bdnf. |
2016-06-01 |
2023-08-13 |
rat |