| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sukumar Chattopadhyay, Sraboni Bhaumik, Madhumita Purkayastha, Srabanti Basu, Aditi Nag Chaudhuri, Shyamal Das Gupt. Apoptosis and necrosis in developing brain cells due to arsenic toxicity and protection with antioxidants. Toxicology letters. vol 136. issue 1. 2002-12-02. PMID:12368058. |
experiments on human fetal brain explants on exposure to arsenic in culture showed disturbance in lipid peroxidation, generation of nitric oxide (no), reactive oxygen species (ros) and apoptosis. |
2002-12-02 |
2023-08-12 |
human |
| Joanne E Carter, Ai Q Truong-Tran, Dion Grosser, Lien Ho, Richard E Ruffin, Peter D Zalewsk. Involvement of redox events in caspase activation in zinc-depleted airway epithelial cells. Biochemical and biophysical research communications. vol 297. issue 4. 2002-11-27. PMID:12359264. |
depletion of intracellular zn(2+) in sheep aec, using the membrane permeant zn(2+) chelator tpen, increased lipid peroxidation in the apical cell membranes (as assessed by immunofluorescence with anti-hydroxynonenal) as well as increasing activated pro-caspase-3 and apoptosis. |
2002-11-27 |
2023-08-12 |
human |
| Dean G Tang, Eunhye La, Julie Kern, James P Kehre. Fatty acid oxidation and signaling in apoptosis. Biological chemistry. vol 383. issue 3-4. 2002-11-25. PMID:12033433. |
also, the spontaneous oxidation of polyunsaturated fatty acids yields reactive aldehydes and other products of lipid peroxidation that are potentially toxic to cells and may also signal apoptosis. |
2002-11-25 |
2023-08-12 |
Not clear |
| David Shi, Bing-Hua Jian. Antioxidant properties of apple juice and its protection against Cr(VI)-induced cellular injury. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. vol 21. issue 3. 2002-11-25. PMID:12435076. |
apple juice reduced cr(vi)-induced lipid peroxidation, dna damage, cell apoptosis, and nf-kappab activation in human lung epithelial a549 cells. |
2002-11-25 |
2023-08-12 |
human |
| David Shi, Bing-Hua Jian. Antioxidant properties of apple juice and its protection against Cr(VI)-induced cellular injury. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. vol 21. issue 3. 2002-11-25. PMID:12435076. |
the lipid peroxidation was measured by a colorimetric assay, dna damage by single cell gel electrophoresis assay, induction of cell apoptosis by flow cytometry, and activation of nf-kappab by luciferase assay. |
2002-11-25 |
2023-08-12 |
human |
| A Oliveros-Juste, V Bertol, A Oliveros-Ci. [Preventive prophylactic treatment in posttraumatic epilepsy]. Revista de neurologia. vol 34. issue 5. 2002-11-08. PMID:12040514. |
prophylactic efficacy of other drugs, like lipid peroxidation inhibitors, neuroprotectors (especially antioxidants), glutamic receptor blockers, nmda receptor blockers, and drugs that modulate apoptosis via caspasas inhibition; however, they constitute new ways of therapeutic investigation with a strong experimental basis. |
2002-11-08 |
2023-08-12 |
Not clear |
| Jeffrey J Lysiak, Quoc An T Nguyen, Terry T Turne. Peptide and nonpeptide reactive oxygen scavengers provide partial rescue of the testis after torsion. Journal of andrology. vol 23. issue 3. 2002-10-23. PMID:12002442. |
results revealed that the infusion of h2o2 increased testicular lipid peroxidation 1 hour after administration and increased germ cell apoptosis within 24 hours of administration. |
2002-10-23 |
2023-08-12 |
rat |
| BaoJun Chang, Manabu Nishikawa, Eisuke Sato, Kozo Utsumi, Masayasu Inou. L-Carnitine inhibits cisplatin-induced injury of the kidney and small intestine. Archives of biochemistry and biophysics. vol 405. issue 1. 2002-10-17. PMID:12176057. |
cisplatin-induced mitochondrial dysfunction and dna (mtdna) injury, lipid peroxidation, and apoptosis of epithelial cells in the kidney and small intestine were strongly inhibited by l-carnitine. |
2002-10-17 |
2023-08-12 |
Not clear |
| Ho-Jin Heo, Hong-Yon Cho, Bumshik Hong, Hye-Kyung Kim, Tae-Ryeon Heo, Eun-Ki Kim, Sung-Koo Kim, Chang-Ju Kim, Dong-Hoon Shi. Ursolic acid of Origanum majorana L. reduces Abeta-induced oxidative injury. Molecules and cells. vol 13. issue 1. 2002-10-10. PMID:11911474. |
amyloid beta protein (abeta) increases free radical production and lipid peroxidation in pc12 nerve cells, leading to apoptosis and cell death. |
2002-10-10 |
2023-08-12 |
Not clear |
| Irfan Rahman, Annemarie A M van Schadewijk, Ann J L Crowther, Pieter S Hiemstra, Jan Stolk, William MacNee, Willem I De Boe. 4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease. American journal of respiratory and critical care medicine. vol 166. issue 4. 2002-09-06. PMID:12186826. |
4-hydroxy-2-nonenal (4-hne), a highly reactive diffusible product of lipid peroxidation, is a key mediator of oxidant-induced cell signaling and apoptosis. |
2002-09-06 |
2023-08-12 |
human |
| Carole Miguet-Alfonsi, Céline Prunet, Serge Monier, Ginette Bessède, Stéphanie Lemaire-Ewing, Arnaud Berthier, Franck Ménétrier, Dominique Néel, Philippe Gambert, Gérard Lizar. Analysis of oxidative processes and of myelin figures formation before and after the loss of mitochondrial transmembrane potential during 7beta-hydroxycholesterol and 7-ketocholesterol-induced apoptosis: comparison with various pro-apoptotic chemicals. Biochemical pharmacology. vol 64. issue 3. 2002-09-05. PMID:12147305. |
to determine the precise relationships between cytotoxicity and oxidative stress, the ability of oxysterols oxidized at c7 to induce apoptosis, to stimulate o2*- production and to promote lipid peroxidation was compared with different pro-apoptotic chemicals: antitumoral drugs (vb, ara-c, chx, and vp-16) and sts. |
2002-09-05 |
2023-08-12 |
Not clear |
| Carole Miguet-Alfonsi, Céline Prunet, Serge Monier, Ginette Bessède, Stéphanie Lemaire-Ewing, Arnaud Berthier, Franck Ménétrier, Dominique Néel, Philippe Gambert, Gérard Lizar. Analysis of oxidative processes and of myelin figures formation before and after the loss of mitochondrial transmembrane potential during 7beta-hydroxycholesterol and 7-ketocholesterol-induced apoptosis: comparison with various pro-apoptotic chemicals. Biochemical pharmacology. vol 64. issue 3. 2002-09-05. PMID:12147305. |
they also suggest that enhancement of o2*- production associated with lipid peroxidation during 7beta-hydroxycholesterol and 7-ketocholesterol-induced apoptosis could contribute to in vivo vascular injury, and that myelin figures could constitute suitable markers of oxysterol-induced cell death. |
2002-09-05 |
2023-08-12 |
Not clear |
| Tiago Rodrigues, Antonio C Santos, Acácio A Pigoso, Fábio E Mingatto, Sérgio A Uyemura, Carlos Curt. Thioridazine interacts with the membrane of mitochondria acquiring antioxidant activity toward apoptosis--potentially implicated mechanisms. British journal of pharmacology. vol 136. issue 1. 2002-08-15. PMID:11976278. |
we conclude that thioridazine interacts with the inner membrane of mitochondria, more likely close to its surface, acquiring antioxidant activity toward processes with potential implications in apoptosis such as o2*- accumulation, as well as lpo, mpt and associated release of cytochrome c. |
2002-08-15 |
2023-08-12 |
Not clear |
| Alison Colquhou. Gamma-linolenic acid alters the composition of mitochondrial membrane subfractions, decreases outer mitochondrial membrane binding of hexokinase and alters carnitine palmitoyltransferase I properties in the Walker 256 rat tumour. Biochimica et biophysica acta. vol 1583. issue 1. 2002-08-06. PMID:12069851. |
these effects, together with previously reported increases in lipid peroxidation, lead to the conclusion that gla may cause inhibition of tumour cell growth through separate but interlinked pathways, all of which eventually lead to apoptosis and a decrease in tumour development. |
2002-08-06 |
2023-08-12 |
rat |
| Anna A Shvedova, Julia Y Tyurina, Kazuaki Kawai, Vladimir A Tyurin, Choudari Kommineni, Vincent Castranova, James P Fabisiak, Valerian E Kaga. Selective peroxidation and externalization of phosphatidylserine in normal human epidermal keratinocytes during oxidative stress induced by cumene hydroperoxide. The Journal of investigative dermatology. vol 118. issue 6. 2002-08-02. PMID:12060396. |
lipid peroxidation is of fundamental interest in the cellular response to peroxides, as lipids are extremely sensitive to oxidation and lipid-based signaling systems have been implicated in a number of cellular processes, including apoptosis. |
2002-08-02 |
2023-08-12 |
human |
| V S Slyshenkov, K Piwocka, E Sikora, L Wojtcza. Pantothenic acid protects jurkat cells against ultraviolet light-induced apoptosis. Free radical biology & medicine. vol 30. issue 11. 2002-07-30. PMID:11368928. |
both pantothenic acid and n-acetylcysteine alleviated the ultraviolet-induced decrease of glutathione content, diminished lipid peroxidation, and partly protected the cells against apoptosis produced by ultraviolet irradiation. |
2002-07-30 |
2023-08-12 |
human |
| Oxana R Kunduzova, Pascale Bianchi, Nathalie Pizzinat, Ghislaine Escourrou, Marie-Helene Seguelas, Angelo Parini, Claudie Cambo. Regulation of JNK/ERK activation, cell apoptosis, and tissue regeneration by monoamine oxidases after renal ischemia-reperfusion. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 16. issue 9. 2002-07-23. PMID:12039844. |
rat pretreatment with the irreversible mao inhibitor pargyline resulted in the following: i) prevented h2o2 production and lipid peroxidation; ii) decreased tubular cell apoptosis and necrosis, measured by tunel staining and histomorphological criteria; and iii) increased tubular cell proliferation as determined by proliferating cell nuclear antigen expression. |
2002-07-23 |
2023-08-12 |
rat |
| Basil A Stol. N-3 fatty acids and lipid peroxidation in breast cancer inhibition. The British journal of nutrition. vol 87. issue 3. 2002-06-24. PMID:12064327. |
in mammary tumours, it is observed that long-chain fa not only increase apoptosis, but also increase lipid peroxidation, and the apoptotic effect can be reversed by antioxidants. |
2002-06-24 |
2023-08-12 |
mouse |
| Yoshihiro Higuchi, Tanihiro Yoshimot. Arachidonic acid converts the glutathione depletion-induced apoptosis to necrosis by promoting lipid peroxidation and reducing caspase-3 activity in rat glioma cells. Archives of biochemistry and biophysics. vol 400. issue 1. 2002-05-06. PMID:11913980. |
arachidonic acid converts the glutathione depletion-induced apoptosis to necrosis by promoting lipid peroxidation and reducing caspase-3 activity in rat glioma cells. |
2002-05-06 |
2023-08-12 |
rat |
| Yoshihiro Higuchi, Tanihiro Yoshimot. Arachidonic acid converts the glutathione depletion-induced apoptosis to necrosis by promoting lipid peroxidation and reducing caspase-3 activity in rat glioma cells. Archives of biochemistry and biophysics. vol 400. issue 1. 2002-05-06. PMID:11913980. |
these results suggest that aa promotes cell death by changing to necrosis from apoptosis through lipid peroxidation initiated by lipid hydroperoxides produced by 12-lipoxygenase under the gsh depletion in c6 cells. |
2002-05-06 |
2023-08-12 |
rat |