| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tsugunobu Andoh, P Boon Chock, Chuang Chin Chiue. The roles of thioredoxin in protection against oxidative stress-induced apoptosis in SH-SY5Y cells. The Journal of biological chemistry. vol 277. issue 12. 2002-04-29. PMID:11751890. |
the reduced form of trx suppresses the serum-free-induced hydroxyl radicals, lipid peroxidation, and apoptosis, indicating that h(2)o(2) is removed by trx peroxidase. |
2002-04-29 |
2023-08-12 |
human |
| H J Heo, H Y Cho, B Hong, H K Kim, E K Kim, B G Kim, D H Shi. Protective effect of 4',5-dihydroxy-3',6,7-trimethoxyflavone from Artemisia asiatica against Abeta-induced oxidative stress in PC12 cells. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. vol 8. issue 3. 2002-04-05. PMID:11676296. |
abeta increased free radical production and lipid peroxidation in pc12 nerve cells, leading to apoptosis and cell death. |
2002-04-05 |
2023-08-12 |
Not clear |
| Janet Liversidge, Andrew Dick, Sharon Gordo. Nitric oxide mediates apoptosis through formation of peroxynitrite and Fas/Fas-ligand interactions in experimental autoimmune uveitis. The American journal of pathology. vol 160. issue 3. 2002-04-02. PMID:11891189. |
inducible nitric oxide synthase (nos2) expression was primarily restricted to infiltrating monocytes/macrophages in the outer retina and photoreceptor rod outer segments (target tissue), but despite showing evidence of lipid peroxidation, myeloid cells remained resistant to apoptosis. |
2002-04-02 |
2023-08-12 |
Not clear |
| Romilda Cardin, Antonia D'Errico, Michelangelo Fiorentino, Attilio Cecchetto, Remo Naccarato, Fabio Farinat. Hepatocyte proliferation and apoptosis in relation to oxidative damage in alcohol-related liver disease. Alcohol and alcoholism (Oxford, Oxfordshire). vol 37. issue 1. 2002-03-28. PMID:11825856. |
the aims of this study were to correlate lipid peroxidation, antioxidant defence and iron metabolism with cell proliferation and apoptosis in alcoholic liver injury, and also in comparison with virus-related liver disease. |
2002-03-28 |
2023-08-12 |
human |
| J Li, R Zheng, J Li, Z Wan. Mechanisms of the induction of apoptosis in human hepatoma cells by tumour necrosis factor-alpha. Cell biology international. vol 25. issue 12. 2002-03-19. PMID:11748914. |
the findings suggest that tnf-alpha-induced apoptosis may be involved in stimulating ca(2+)-dependent endonuclease activity and increasing membrane lipid peroxidation. |
2002-03-19 |
2023-08-12 |
human |
| L B Dudnik, A N Tsyupko, A V Khrenov, A V Alessenk. Effect of bilirubin on lipid peroxidation, sphingomyelinase activity, and apoptosis induced by sphingosine and UV irradiation. Biochemistry. Biokhimiia. vol 66. issue 9. 2002-03-05. PMID:11703186. |
effect of bilirubin on lipid peroxidation, sphingomyelinase activity, and apoptosis induced by sphingosine and uv irradiation. |
2002-03-05 |
2023-08-12 |
mouse |
| L B Dudnik, A N Tsyupko, A V Khrenov, A V Alessenk. Effect of bilirubin on lipid peroxidation, sphingomyelinase activity, and apoptosis induced by sphingosine and UV irradiation. Biochemistry. Biokhimiia. vol 66. issue 9. 2002-03-05. PMID:11703186. |
the effect of bilirubin (br) on sphingomyelin cycle activity, lipid peroxidation (lpo), and apoptosis induced by sphingosine and uv irradiation has been studied in vivo. |
2002-03-05 |
2023-08-12 |
mouse |
| Yusong Yang, Rajendra Sharma, Ji-Zhong Cheng, Manjit K Saini, Naseem H Ansari, Usha P Andley, Sanjay Awasthi, Yogesh C Awasth. Protection of HLE B-3 cells against hydrogen peroxide- and naphthalene-induced lipid peroxidation and apoptosis by transfection with hGSTA1 and hGSTA2. Investigative ophthalmology & visual science. vol 43. issue 2. 2002-02-14. PMID:11818388. |
protection of hle b-3 cells against hydrogen peroxide- and naphthalene-induced lipid peroxidation and apoptosis by transfection with hgsta1 and hgsta2. |
2002-02-14 |
2023-08-12 |
human |
| F J Li, T Kondo, Q L Zhao, K Tanabe, R Ogawa, M Li, Y Ara. Enhancement of hyperthermia-induced apoptosis by a free radical initiator, 2,2'-azobis (2-amidinopropane) dihydrochloride, in human histiocytic lymphoma U937 cells. Free radical research. vol 35. issue 3. 2002-01-25. PMID:11697127. |
these results suggest that apoptosis induced by hyperthermia alone is due to the increase in [ca2+]i arising from increased expression of ip3r1 and lpo. |
2002-01-25 |
2023-08-12 |
human |
| F J Li, T Kondo, Q L Zhao, K Tanabe, R Ogawa, M Li, Y Ara. Enhancement of hyperthermia-induced apoptosis by a free radical initiator, 2,2'-azobis (2-amidinopropane) dihydrochloride, in human histiocytic lymphoma U937 cells. Free radical research. vol 35. issue 3. 2002-01-25. PMID:11697127. |
additional increase in [ca2+]i due to increased lpo and the activation of mitochondria-caspase dependent pathway play a major role in the enhancement of apoptosis by the combination with hyperthermia and aaph. |
2002-01-25 |
2023-08-12 |
human |
| Z Z Guan, X Zhang, M Mousavi, J Y Tian, C Unger, A Nordber. Reduced expression of neuronal nicotinic acetylcholine receptors during the early stages of damage by oxidative stress in PC12 cells. Journal of neuroscience research. vol 66. issue 4. 2002-01-24. PMID:11746374. |
the results showed that free radical insult (feso(4)) within the concentration range (1 -100 microm) used in the study induced dose-dependent increases in lipid peroxidation and toxicity to pc12 cells, but did not result in apoptosis or necrosis. |
2002-01-24 |
2023-08-12 |
Not clear |
| A Colquhoun, R I Schumache. gamma-Linolenic acid and eicosapentaenoic acid induce modifications in mitochondrial metabolism, reactive oxygen species generation, lipid peroxidation and apoptosis in Walker 256 rat carcinosarcoma cells. Biochimica et biophysica acta. vol 1533. issue 3. 2001-12-13. PMID:11731331. |
gamma-linolenic acid and eicosapentaenoic acid induce modifications in mitochondrial metabolism, reactive oxygen species generation, lipid peroxidation and apoptosis in walker 256 rat carcinosarcoma cells. |
2001-12-13 |
2023-08-12 |
rat |
| S Takano, Y Aramaki, S Tsuchiy. Lipoxygenase may be involved in cationic liposome-induced macrophage apoptosis. Biochemical and biophysical research communications. vol 288. issue 1. 2001-12-07. PMID:11594761. |
furthermore, lipid peroxidation was observed following liposome treatment, but the apoptosis was not inhibited by the antioxidant alpha-tocopherol. |
2001-12-07 |
2023-08-12 |
Not clear |
| S Takano, Y Aramaki, S Tsuchiy. Lipoxygenase may be involved in cationic liposome-induced macrophage apoptosis. Biochemical and biophysical research communications. vol 288. issue 1. 2001-12-07. PMID:11594761. |
these findings suggested that lipoxygenase is responsible for ros generation, and ros but not lipid peroxidation acts as a key mediator in the progress of apoptosis induced by cationic liposomes. |
2001-12-07 |
2023-08-12 |
Not clear |
| C Ji, V Amarnath, J A Pietenpol, L J Marnet. 4-hydroxynonenal induces apoptosis via caspase-3 activation and cytochrome c release. Chemical research in toxicology. vol 14. issue 8. 2001-11-01. PMID:11511183. |
we investigated the mechanism by which 4-hydroxynonenal (hne), a major aldehydic product of lipid peroxidation, induces apoptosis in tumor cells. |
2001-11-01 |
2023-08-12 |
human |
| C D Anuradha, S Kanno, S Hiran. Oxidative damage to mitochondria is a preliminary step to caspase-3 activation in fluoride-induced apoptosis in HL-60 cells. Free radical biology & medicine. vol 31. issue 3. 2001-10-18. PMID:11461774. |
these results suggested that perhaps naf induced apoptosis by oxidative stress-induced lipid peroxidation, causing loss of deltapsi(m), and thereby releasing cytochrome c into the cytosol and further triggering the caspase cascade leading to apoptotic cell death in hl-60 cells. |
2001-10-18 |
2023-08-12 |
Not clear |
| A Agrawal, R K Kal. Radiation induced peroxidative damage: mechanism and significance. Indian journal of experimental biology. vol 39. issue 4. 2001-09-20. PMID:11491573. |
recent findings related to the close link between radiation-induced lipid peroxidation and apoptosis are likely to open new avenues for future research and to develop new approaches for radiomodification of biological effects. |
2001-09-20 |
2023-08-12 |
Not clear |
| B C Kim, B S Shon, Y W Ryoo, S P Kim, K S Le. Melatonin reduces X-ray irradiation-induced oxidative damages in cultured human skin fibroblasts. Journal of dermatological science. vol 26. issue 3. 2001-08-09. PMID:11390204. |
this study suggests that melatonin pretreatment inhibits radiation-induced apoptosis, and melatonin exerts its radioprotective effect by inhibition of lipid peroxidation and without any involvement of the p53/p21 pathway. |
2001-08-09 |
2023-08-12 |
human |
| Y Yang, J Z Cheng, S S Singhal, M Saini, U Pandya, S Awasthi, Y C Awasth. Role of glutathione S-transferases in protection against lipid peroxidation. Overexpression of hGSTA2-2 in K562 cells protects against hydrogen peroxide-induced apoptosis and inhibits JNK and caspase 3 activation. The Journal of biological chemistry. vol 276. issue 22. 2001-07-26. PMID:11279091. |
hgsta2 transfection does not affect the function of antioxidant enzymes including gpx activity toward h(2)o(2) suggesting that the alpha class gsts play an important role in regulation of the intracellular concentrations of the lipid peroxidation products that may be involved in the signaling mechanisms of apoptosis. |
2001-07-26 |
2023-08-12 |
human |
| G Spitelle. Peroxidation of linoleic acid and its relation to aging and age dependent diseases. Mechanisms of ageing and development. vol 122. issue 7. 2001-07-12. PMID:11322990. |
it is speculated that the change from enzymic to nonenzymic lpo is connected with the switch from apoptosis to necrosis and that loohs produced in enzymic reactions are degraded specifically to signal compounds which induce physiological responses, while nonenzymic reactions seem to induce generation of reactive oxygen species, cell death and age related diseases. |
2001-07-12 |
2023-08-12 |
Not clear |