| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jingyao Yang, Long Li, Xiaoxiao Zheng, Zhaoyang Lu, Hua Zho. Dapagliflozin attenuates myocardial hypertrophy via activating the SIRT1/HIF-1α signaling pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 165. 2023-07-08. PMID:37421782. |
in mice stimulated with ang ii, the degree of myocardial fibrosis and upregulation of the markers of cardiac hypertrophy (atrial natriuretic peptide, anp and b-type natriuretic peptide, bnp) were attenuated by dapa. |
2023-07-08 |
2023-08-14 |
mouse |
| Jingyao Yang, Long Li, Xiaoxiao Zheng, Zhaoyang Lu, Hua Zho. Dapagliflozin attenuates myocardial hypertrophy via activating the SIRT1/HIF-1α signaling pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 165. 2023-07-08. PMID:37421782. |
taken together, activating the sirt1/hif-1α signaling pathway was found to confer a protective effect against experimental myocardial hypertrophy in mice induced by ang ii, demonstrating its potential as an effective therapeutic target for pathological cardiac hypertrophy. |
2023-07-08 |
2023-08-14 |
mouse |
| Keisuke Okuno, Keiichi Torimoto, Ryohei Kuroda, Stephanie M Cicalese, Yoshiharu Okuno, Ryohei Kono, Shinsuke Marumoto, Hirotoshi Utsunomiya, Satoru Eguch. Infused juice concentrate of Japanese plum Prunus mume attenuates inflammatory vascular remodeling in a mouse model of hypertension induced by angiotensin II. Hypertension research : official journal of the Japanese Society of Hypertension. 2023-06-12. PMID:37308550. |
aortic medial hypertrophy was observed in control mice after ang ii infusion, which was attenuated in bainiku-ekisu group with ang ii infusion. |
2023-06-12 |
2023-08-14 |
mouse |
| Keisuke Okuno, Keiichi Torimoto, Ryohei Kuroda, Stephanie M Cicalese, Yoshiharu Okuno, Ryohei Kono, Shinsuke Marumoto, Hirotoshi Utsunomiya, Satoru Eguch. Infused juice concentrate of Japanese plum Prunus mume attenuates inflammatory vascular remodeling in a mouse model of hypertension induced by angiotensin II. Hypertension research : official journal of the Japanese Society of Hypertension. 2023-06-12. PMID:37308550. |
echocardiograph indicated protection of ang ii-induced cardiac hypertrophy by bainiku-ekisu. |
2023-06-12 |
2023-08-14 |
mouse |
| Xiangxiang Wei, Jiayu Jin, Jian Wu, Yunquan He, Jieyu Guo, Zhaohua Yang, Liang Chen, Kui Hu, Liliang Li, Mengping Jia, Qinhan Li, Xiaoyu Lv, Fei Ge, Siyu Ma, Huijie Wu, Xiuling Zhi, Xinhong Wang, Lindi Jiang, Elena Osto, Jianyi Zhang, Dan Men. Cardiac-specific BACH1 ablation attenuates pathological cardiac hypertrophy by inhibiting the Ang II type 1 receptor expression and the Ca2+/CaMKII pathway. Cardiovascular research. 2023-06-06. PMID:37279500. |
cardiac-specific bach1 ablation attenuates pathological cardiac hypertrophy by inhibiting the ang ii type 1 receptor expression and the ca2+/camkii pathway. |
2023-06-06 |
2023-08-14 |
Not clear |
| Tianxiang Yu, Xiangwei Xu, Jiajia Wei, Jiachen Xu, Wu Luo, Ankang Li, Guang Liang, Mengyang Wan. Ginsenoside Rg5 alleviates Ang II-induced cardiac inflammation and remodeling by inhibiting the JNK/AP-1 pathway. International immunopharmacology. vol 120. 2023-06-05. PMID:37276830. |
it was discovered that rg5 inhibited cardiac inflammation, myocardial fibrosis, and hypertrophy, and prevented cardiac malfunction in mice challenged with ang ii, without altering blood pressure. |
2023-06-05 |
2023-08-14 |
mouse |
| Ye Lu, Zhaoxiang Zeng, Xianhao Bao, Mingwei Wu, Zaiping Jing, Jiaxuan Fen. Pristimerin protects against pathological cardiac hypertrophy through improvement of PPARα pathway. Toxicology and applied pharmacology. 2023-06-03. PMID:37269933. |
likewise, pm incubation dramatically reversed ang ii-mediated cardiomyocytes hypertrophy in nrcms. |
2023-06-03 |
2023-08-14 |
mouse |
| Rui Yang, Liangliang Li, Yumeng Hou, Yingnan Li, Jing Zhang, Na Yang, Yuhan Zhang, Weihang Ji, Tong Yu, Lifang Lv, Haihai Liang, Xuelian Li, Tianyu Li, Hongli Sha. Long non-coding RNA KCND1 protects hearts from hypertrophy by targeting YBX1. Cell death & disease. vol 14. issue 5. 2023-05-30. PMID:37253771. |
in this study, we found that lncrna kcnd1 (lnckcnd1) was downregulated in both transverse aortic constriction (tac)-induced hypertrophic mouse hearts and angiotensin ii (ang ii)-induced neonatal mouse cardiomyocytes. |
2023-05-30 |
2023-08-14 |
mouse |
| Rui Yang, Liangliang Li, Yumeng Hou, Yingnan Li, Jing Zhang, Na Yang, Yuhan Zhang, Weihang Ji, Tong Yu, Lifang Lv, Haihai Liang, Xuelian Li, Tianyu Li, Hongli Sha. Long non-coding RNA KCND1 protects hearts from hypertrophy by targeting YBX1. Cell death & disease. vol 14. issue 5. 2023-05-30. PMID:37253771. |
in contrast, overexpression of lnckcnd1 inhibited ang ii-induced cardiomyocyte hypertrophic changes. |
2023-05-30 |
2023-08-14 |
mouse |
| Rui Yang, Liangliang Li, Yumeng Hou, Yingnan Li, Jing Zhang, Na Yang, Yuhan Zhang, Weihang Ji, Tong Yu, Lifang Lv, Haihai Liang, Xuelian Li, Tianyu Li, Hongli Sha. Long non-coding RNA KCND1 protects hearts from hypertrophy by targeting YBX1. Cell death & disease. vol 14. issue 5. 2023-05-30. PMID:37253771. |
furthermore, ybx1 was downregulated during cardiac hypertrophy, whereas overexpression of ybx1 inhibited ang ii-induced cardiomyocyte hypertrophy. |
2023-05-30 |
2023-08-14 |
mouse |
| Limin Zhang, Huihui Wang, Weimin L. PRMT5 up-regulation improves myocardial hypertrophy by mediating E2F-1/NF-κB/NLRP3 pathway. Preventive medicine. 2023-05-22. PMID:37217036. |
results shows that prmt5 was down-regulated in the tac rat model as well as in an in-vitro model of ang ii-induced myocardial hypertrophy. |
2023-05-22 |
2023-08-14 |
rat |
| Limin Zhang, Huihui Wang, Weimin L. PRMT5 up-regulation improves myocardial hypertrophy by mediating E2F-1/NF-κB/NLRP3 pathway. Preventive medicine. 2023-05-22. PMID:37217036. |
overexpression of prmt5 dramatically reduced ang ii-induced myocardial hypertrophy, fibrosis, inflammatory response, and oxidative stress, whereas knockdown of prmt5 had the opposite effect. |
2023-05-22 |
2023-08-14 |
rat |
| Ahmad H Alammari, Samar H Gerges, Fadumo Ahmed Isse, Ayman O S El-Kad. Drug metabolism and disposition: the biological fate of chemicals. 2023-05-15. PMID:37185150. |
this study investigates the role of ficz on ahr and cyp1a1 mediated aa metabolism and whether it attenuate angiotensin (ang) ii-induced cardiac hypertrophy. |
2023-05-15 |
2023-08-14 |
human |
| Ahmad H Alammari, Samar H Gerges, Fadumo Ahmed Isse, Ayman O S El-Kad. Drug metabolism and disposition: the biological fate of chemicals. 2023-05-15. PMID:37185150. |
our results show that ang ii-induced cardiac hypertrophy modulates aa metabolites in an enantioselective manner, and that ficz activates ahr in a time dependent manner, inhibits ahr proteasomal degradation, induces cyp1a1, increases the concentration of 19(s)-hete and attenuate ang ii-induced cardiac hypertrophy by inhibiting the hypertrophic markers and decreasing cell surface area through midchain-hetes dependent mechanism. |
2023-05-15 |
2023-08-14 |
human |
| Ahmad H Alammari, Samar H Gerges, Fadumo Ahmed Isse, Ayman O S El-Kad. Drug metabolism and disposition: the biological fate of chemicals. 2023-05-15. PMID:37185150. |
in conclusion, the results demonstrate the ability of ficz to protects against ang ii-induced cardiac hypertrophy by increasing the concentration of 19(s)-hete through ahr regulated enzyme induction and inhibition of midchain-hetes metabolites. |
2023-05-15 |
2023-08-14 |
human |
| Rukhsana Gul, Mushtaq A Dar, Shahid Nawaz, Assim A Alfadd. Protective Effects of Nanoceria against Mitochondrial Dysfunction and Angiotensin II-Induced Hypertrophy in H9c2 Cardiomyoblasts. Antioxidants (Basel, Switzerland). vol 12. issue 4. 2023-04-28. PMID:37107252. |
our data revealed that pretreatment of h9c2 cardiomyoblasts with nanoceria significantly prevented ang ii-stimulated generation of intracellular ros, aberrant expression of pro-inflammatory cytokines, and hypertrophy markers. |
2023-04-28 |
2023-08-14 |
cat |
| Rukhsana Gul, Mushtaq A Dar, Shahid Nawaz, Assim A Alfadd. Protective Effects of Nanoceria against Mitochondrial Dysfunction and Angiotensin II-Induced Hypertrophy in H9c2 Cardiomyoblasts. Antioxidants (Basel, Switzerland). vol 12. issue 4. 2023-04-28. PMID:37107252. |
collectively, these findings demonstrate the protective effects of nanoceria against ang ii-mediated mitochondrial dysfunction and pathological hypertrophy in h9c2 cells. |
2023-04-28 |
2023-08-14 |
cat |
| Qi Zhang, Yue Shen, Sayeman Islam Niloy, Stephen T O'Rourke, Chengwen Su. Chronic Effects of Apelin on Cardiovascular Regulation and Angiotensin II-Induced Hypertension. Pharmaceuticals (Basel, Switzerland). vol 16. issue 4. 2023-04-28. PMID:37111357. |
however, under the same condition, the chronic infusion of ang ii induced significant bp elevation, cardiac hypertrophy, and fibrosis. |
2023-04-28 |
2023-08-14 |
rat |
| Qi Zhang, Yue Shen, Sayeman Islam Niloy, Stephen T O'Rourke, Chengwen Su. Chronic Effects of Apelin on Cardiovascular Regulation and Angiotensin II-Induced Hypertension. Pharmaceuticals (Basel, Switzerland). vol 16. issue 4. 2023-04-28. PMID:37111357. |
taken together, our experiments showed an unexpected result indicating that the chronic administration of apelin-13 did not alter basal bp, nor did it change ang ii-induced hypertension and cardiac hypertrophy. |
2023-04-28 |
2023-08-14 |
rat |
| Daoyao Fu, Jing Luo, Yanze Wu, Liuping Zhang, Lei Li, Hui Chen, Tong Wen, Yongnan Fu, Wenjun Xion. Angiotensin II-induced calcium overload affects mitochondrial functions in cardiac hypertrophy by targeting the USP2/MFN2 axis. Molecular and cellular endocrinology. 2023-04-26. PMID:37100191. |
animal and cell models of cardiac hypertrophy were established using angiotensin ii (ang ii) induction. |
2023-04-26 |
2023-08-14 |
Not clear |