| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Nagano, J Higaki, F Nakamura, K Higashimori, N Nagano, H Mikami, T Ogihar. Role of cardiac angiotensin II in isoproterenol-induced left ventricular hypertrophy. Hypertension (Dallas, Tex. : 1979). vol 19. issue 6 Pt 2. 1992-06-30. PMID:1534315. |
these results suggest that cardiac tissue ang ii regulates myocyte growth in isoproterenol-induced lv hypertrophy, and the reduction of ang ii partly explains the prevention of cardiac hypertrophy by the converting enzyme inhibitor. |
1992-06-30 |
2023-08-11 |
rat |
| H Tseng, B C Ber. The Na/K/2Cl cotransporter is increased in hypertrophied vascular smooth muscle cells. The Journal of biological chemistry. vol 267. issue 12. 1992-05-28. PMID:1569072. |
because the na+/h+ exchanger plays an important role in volume regulation and because we previously observed long term alterations in na+/h+ exchange and phi in response to angiotensin-ii-induced (ang ii) hypertrophy, we studied cell-acidifying mechanisms. |
1992-05-28 |
2023-08-11 |
Not clear |
| H Tseng, B C Ber. The Na/K/2Cl cotransporter is increased in hypertrophied vascular smooth muscle cells. The Journal of biological chemistry. vol 267. issue 12. 1992-05-28. PMID:1569072. |
these findings demonstrate that na/k/2cl cotransport activity is specifically induced in ang ii-hypertrophied vsmc and establish this transporter as a component of the hypertrophic growth response. |
1992-05-28 |
2023-08-11 |
Not clear |
| R J Johnson, C E Alpers, A Yoshimura, D Lombardi, P Pritzl, J Floege, S M Schwart. Renal injury from angiotensin II-mediated hypertension. Hypertension (Dallas, Tex. : 1979). vol 19. issue 5. 1992-05-27. PMID:1568765. |
angiotensin ii (ang ii)-mediated hypertension induces vascular smooth muscle cell hypertrophy and hyperplasia in systemic blood vessels, but the effects of ang ii on the intrinsic cell populations within the kidney have been less well characterized. |
1992-05-27 |
2023-08-11 |
rat |
| A Veltmar, P Gohlke, T Unge. From tissue angiotensin converting enzyme inhibition to antihypertensive effect. American journal of hypertension. vol 4. issue 3 Pt 2. 1991-07-18. PMID:2043316. |
in the vascular wall, a local inhibition of ang ii synthesis may contribute not only to the reduction of vascular tone but also to the marked regression of media hypertrophy seen after ce inhibitor treatment. |
1991-07-18 |
2023-08-11 |
Not clear |
| H Itoh, R E Pratt, V J Dza. Interaction of atrial natriuretic polypeptide and angiotensin II on protooncogene expression and vascular cell growth. Biochemical and biophysical research communications. vol 176. issue 3. 1991-07-03. PMID:1828153. |
recent evidence suggests that vasoconstrictive substances, including angiotensin ii (ang ii), may function as a vascular smooth muscle growth promoting substance and may contribute to vascular hypertrophy in hypertension. |
1991-07-03 |
2023-08-11 |
rat |
| H Itoh, R E Pratt, V J Dza. Interaction of atrial natriuretic polypeptide and angiotensin II on protooncogene expression and vascular cell growth. Biochemical and biophysical research communications. vol 176. issue 3. 1991-07-03. PMID:1828153. |
moreover, we have demonstrated that anp can attenuate ang ii's action on vascular hypertrophy. |
1991-07-03 |
2023-08-11 |
rat |
| H Itoh, R E Pratt, V J Dza. Interaction of atrial natriuretic polypeptide and angiotensin II on protooncogene expression and vascular cell growth. Biochemical and biophysical research communications. vol 176. issue 3. 1991-07-03. PMID:1828153. |
anp (10(-7) m) inhibited the hypertrophic effect of ang ii at the concentration of 10(-10) - 10(-8) m) but exerted no effect on the action of higher doses (10(-7) - 10(-6) m) of ang ii. |
1991-07-03 |
2023-08-11 |
rat |
| J A Millar, E L Harris, N J Cassi. Mitogenesis in cultured vascular smooth muscle cells from two rat models of hypertension in response to fetal calf serum and angiotensin II. Journal of cardiovascular pharmacology. vol 16 Suppl 7. 1991-05-23. PMID:1708014. |
ang ii increased the total well protein content but not protein normalized on cell number, i.e., no hypertrophic effect of ang ii was seen in these actively dividing cells. |
1991-05-23 |
2023-08-11 |
rat |
| M B Turla, M M Thompson, M H Corjay, G K Owen. Mechanisms of angiotensin II- and arginine vasopressin-induced increases in protein synthesis and content in cultured rat aortic smooth muscle cells. Evidence for selective increases in smooth muscle isoactin expression. Circulation research. vol 68. issue 1. 1991-02-07. PMID:1984869. |
previous studies from this laboratory have demonstrated that angiotensin ii (ang ii) and arginine vasopressin (avp) are potent hypertrophic agents in cultured rat aortic smooth muscle cells. |
1991-02-07 |
2023-08-11 |
rat |
| M B Turla, M M Thompson, M H Corjay, G K Owen. Mechanisms of angiotensin II- and arginine vasopressin-induced increases in protein synthesis and content in cultured rat aortic smooth muscle cells. Evidence for selective increases in smooth muscle isoactin expression. Circulation research. vol 68. issue 1. 1991-02-07. PMID:1984869. |
the present study identified major proteins that accumulate in ang ii-induced and avp-induced hypertrophic cells and initiated studies of the mechanisms that contribute to their accumulation. |
1991-02-07 |
2023-08-11 |
rat |
| M B Turla, M M Thompson, M H Corjay, G K Owen. Mechanisms of angiotensin II- and arginine vasopressin-induced increases in protein synthesis and content in cultured rat aortic smooth muscle cells. Evidence for selective increases in smooth muscle isoactin expression. Circulation research. vol 68. issue 1. 1991-02-07. PMID:1984869. |
smooth muscle cell hypertrophy induced by ang ii and/or avp (1 microm each) was associated with widespread increases in the content of many cellular proteins that were resolved by one- and two-dimensional gel electrophoresis. |
1991-02-07 |
2023-08-11 |
rat |
| B A Schölkens, W Lin. Cardioprotective effects of ACE inhibitors: experimental proof and clinical perspectives. Clinical physiology and biochemistry. vol 8 Suppl 1. 1991-01-31. PMID:2147878. |
in cardiac hypertrophy, ace inhibitors capable of affecting tissue ras can induce prevention and regression not only through their blood pressure lowering actions, but possibly also by direct cardiac effects, presumably by inhibition of local ang ii generation, a possible growth factor. |
1991-01-31 |
2023-08-11 |
rat |
| A M Kat. Angiotensin II: hemodynamic regulator or growth factor? Journal of molecular and cellular cardiology. vol 22. issue 7. 1990-12-14. PMID:2231742. |
it is, therefore, probably inappropriate to view ang ii mainly as a vasoconstrictor with secondary effects to induce cell hypertrophy. |
1990-12-14 |
2023-08-11 |
human |
| G Wolf, E G Neilso. Angiotensin II induces cellular hypertrophy in cultured murine proximal tubular cells. The American journal of physiology. vol 259. issue 5 Pt 2. 1990-12-13. PMID:1700629. |
in the present study we demonstrate that a murine proximal tubular cell line (mct cells), expressing angiotensin ii (ang ii) receptors [dissociation constant (kd) = 0.89 nm; receptor density (r0) = 46,900 receptors/cell] in culture, can be induced to hypertrophy after the daily addition of exogenous ang ii (10(-8) m). |
1990-12-13 |
2023-08-11 |
Not clear |
| G Wolf, E G Neilso. Angiotensin II induces cellular hypertrophy in cultured murine proximal tubular cells. The American journal of physiology. vol 259. issue 5 Pt 2. 1990-12-13. PMID:1700629. |
ang ii-induced hypertrophy in mct cells was factor specific, in that it could be blocked with saralasin, and not induced by angiotensin i (ang i). |
1990-12-13 |
2023-08-11 |
Not clear |
| G Wolf, E G Neilso. Angiotensin II induces cellular hypertrophy in cultured murine proximal tubular cells. The American journal of physiology. vol 259. issue 5 Pt 2. 1990-12-13. PMID:1700629. |
ang ii, as well as egf and/or pdgf, moreover, could induce the cellular oncogenes c-fos, c-myc, c-n-ras, but not c-cis, which suggests that early gene activation is probably not a specific prerequisite for hypertrophy. |
1990-12-13 |
2023-08-11 |
Not clear |
| G Wolf, E G Neilso. Angiotensin II induces cellular hypertrophy in cultured murine proximal tubular cells. The American journal of physiology. vol 259. issue 5 Pt 2. 1990-12-13. PMID:1700629. |
our findings demonstrate that ang ii, in culture, can be a single-factor event capable of inducing hypertrophy in proximal tubular cells. |
1990-12-13 |
2023-08-11 |
Not clear |
| A J Naftilan, G K Gilliland, C S Eldridge, A S Kraf. Induction of the proto-oncogene c-jun by angiotensin II. Molecular and cellular biology. vol 10. issue 10. 1990-10-18. PMID:2119001. |
angiotensin (ang) ii causes hypertrophy of rat aortic smooth muscle cells in culture and results in the rapid activation of c-fos. |
1990-10-18 |
2023-08-11 |
rat |
| K M Baker, J F Acet. Angiotensin II stimulation of protein synthesis and cell growth in chick heart cells. The American journal of physiology. vol 259. issue 2 Pt 2. 1990-09-14. PMID:2386231. |
the octapeptide [ile5]angiotensin ii (ang ii), which is the principal circulating hormone of the renin-angiotensin system, could modulate or mediate cardiac hypertrophy via indirect effects, through increases in total peripheral vascular resistance, or by direct effects on cardiac cells, which result in increased protein synthesis and cell growth. |
1990-09-14 |
2023-08-11 |
chicken |