| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M B Turla, M M Thompson, M H Corjay, G K Owen. Mechanisms of angiotensin II- and arginine vasopressin-induced increases in protein synthesis and content in cultured rat aortic smooth muscle cells. Evidence for selective increases in smooth muscle isoactin expression. Circulation research. vol 68. issue 1. 1991-02-07. PMID:1984869. |
previous studies from this laboratory have demonstrated that angiotensin ii (ang ii) and arginine vasopressin (avp) are potent hypertrophic agents in cultured rat aortic smooth muscle cells. |
1991-02-07 |
2023-08-11 |
rat |
| M B Turla, M M Thompson, M H Corjay, G K Owen. Mechanisms of angiotensin II- and arginine vasopressin-induced increases in protein synthesis and content in cultured rat aortic smooth muscle cells. Evidence for selective increases in smooth muscle isoactin expression. Circulation research. vol 68. issue 1. 1991-02-07. PMID:1984869. |
the present study identified major proteins that accumulate in ang ii-induced and avp-induced hypertrophic cells and initiated studies of the mechanisms that contribute to their accumulation. |
1991-02-07 |
2023-08-11 |
rat |
| M B Turla, M M Thompson, M H Corjay, G K Owen. Mechanisms of angiotensin II- and arginine vasopressin-induced increases in protein synthesis and content in cultured rat aortic smooth muscle cells. Evidence for selective increases in smooth muscle isoactin expression. Circulation research. vol 68. issue 1. 1991-02-07. PMID:1984869. |
smooth muscle cell hypertrophy induced by ang ii and/or avp (1 microm each) was associated with widespread increases in the content of many cellular proteins that were resolved by one- and two-dimensional gel electrophoresis. |
1991-02-07 |
2023-08-11 |
rat |
| B A Schölkens, W Lin. Cardioprotective effects of ACE inhibitors: experimental proof and clinical perspectives. Clinical physiology and biochemistry. vol 8 Suppl 1. 1991-01-31. PMID:2147878. |
in cardiac hypertrophy, ace inhibitors capable of affecting tissue ras can induce prevention and regression not only through their blood pressure lowering actions, but possibly also by direct cardiac effects, presumably by inhibition of local ang ii generation, a possible growth factor. |
1991-01-31 |
2023-08-11 |
rat |
| A M Kat. Angiotensin II: hemodynamic regulator or growth factor? Journal of molecular and cellular cardiology. vol 22. issue 7. 1990-12-14. PMID:2231742. |
it is, therefore, probably inappropriate to view ang ii mainly as a vasoconstrictor with secondary effects to induce cell hypertrophy. |
1990-12-14 |
2023-08-11 |
human |
| G Wolf, E G Neilso. Angiotensin II induces cellular hypertrophy in cultured murine proximal tubular cells. The American journal of physiology. vol 259. issue 5 Pt 2. 1990-12-13. PMID:1700629. |
in the present study we demonstrate that a murine proximal tubular cell line (mct cells), expressing angiotensin ii (ang ii) receptors [dissociation constant (kd) = 0.89 nm; receptor density (r0) = 46,900 receptors/cell] in culture, can be induced to hypertrophy after the daily addition of exogenous ang ii (10(-8) m). |
1990-12-13 |
2023-08-11 |
Not clear |
| G Wolf, E G Neilso. Angiotensin II induces cellular hypertrophy in cultured murine proximal tubular cells. The American journal of physiology. vol 259. issue 5 Pt 2. 1990-12-13. PMID:1700629. |
ang ii-induced hypertrophy in mct cells was factor specific, in that it could be blocked with saralasin, and not induced by angiotensin i (ang i). |
1990-12-13 |
2023-08-11 |
Not clear |
| G Wolf, E G Neilso. Angiotensin II induces cellular hypertrophy in cultured murine proximal tubular cells. The American journal of physiology. vol 259. issue 5 Pt 2. 1990-12-13. PMID:1700629. |
ang ii, as well as egf and/or pdgf, moreover, could induce the cellular oncogenes c-fos, c-myc, c-n-ras, but not c-cis, which suggests that early gene activation is probably not a specific prerequisite for hypertrophy. |
1990-12-13 |
2023-08-11 |
Not clear |
| G Wolf, E G Neilso. Angiotensin II induces cellular hypertrophy in cultured murine proximal tubular cells. The American journal of physiology. vol 259. issue 5 Pt 2. 1990-12-13. PMID:1700629. |
our findings demonstrate that ang ii, in culture, can be a single-factor event capable of inducing hypertrophy in proximal tubular cells. |
1990-12-13 |
2023-08-11 |
Not clear |
| A J Naftilan, G K Gilliland, C S Eldridge, A S Kraf. Induction of the proto-oncogene c-jun by angiotensin II. Molecular and cellular biology. vol 10. issue 10. 1990-10-18. PMID:2119001. |
angiotensin (ang) ii causes hypertrophy of rat aortic smooth muscle cells in culture and results in the rapid activation of c-fos. |
1990-10-18 |
2023-08-11 |
rat |
| K M Baker, J F Acet. Angiotensin II stimulation of protein synthesis and cell growth in chick heart cells. The American journal of physiology. vol 259. issue 2 Pt 2. 1990-09-14. PMID:2386231. |
the octapeptide [ile5]angiotensin ii (ang ii), which is the principal circulating hormone of the renin-angiotensin system, could modulate or mediate cardiac hypertrophy via indirect effects, through increases in total peripheral vascular resistance, or by direct effects on cardiac cells, which result in increased protein synthesis and cell growth. |
1990-09-14 |
2023-08-11 |
chicken |
| L Neyses, H Vette. Impaired relaxation of the hypertrophied myocardium is potentiated by angiotensin II. Journal of hypertension. Supplement : official journal of the International Society of Hypertension. vol 7. issue 6. 1990-05-11. PMID:2534400. |
the combination of hypertrophy and high levels of ang ii potentiates relaxation impairment and may therefore contribute to hypertensive left ventricular failure. |
1990-05-11 |
2023-08-11 |
rat |
| A J Naftilan, R E Pratt, C S Eldridge, H L Lin, V J Dza. Angiotensin II induces c-fos expression in smooth muscle via transcriptional control. Hypertension (Dallas, Tex. : 1979). vol 13. issue 6 Pt 2. 1989-08-08. PMID:2737716. |
angiotensin ii (ang ii) has been shown to cause hypertrophy of cultured quiescent rat aortic smooth muscle cells. |
1989-08-08 |
2023-08-11 |
rat |
| A J Naftilan, R E Pratt, C S Eldridge, H L Lin, V J Dza. Angiotensin II induces c-fos expression in smooth muscle via transcriptional control. Hypertension (Dallas, Tex. : 1979). vol 13. issue 6 Pt 2. 1989-08-08. PMID:2737716. |
this observation along with the recent demonstration of angiotensinogen messenger rna (mrna) in the vessel wall has led us to postulate a role for ang ii in hypertensive smooth muscle hypertrophy. |
1989-08-08 |
2023-08-11 |
rat |
| A J Naftilan, R E Pratt, V J Dza. Induction of platelet-derived growth factor A-chain and c-myc gene expressions by angiotensin II in cultured rat vascular smooth muscle cells. The Journal of clinical investigation. vol 83. issue 4. 1989-05-15. PMID:2649516. |
recently, angiotensin ii (ang ii) has been shown to cause hypertrophy of cultured quiescent rat aortic smooth muscle (rasm) cells. |
1989-05-15 |
2023-08-11 |
rat |