| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Fiedler, G Busto. Cortical ablation reduces veratridine evoked release of endogenous glutamate from superfused substantia nigra slices. Neuroscience letters. vol 122. issue 1. 1991-08-01. PMID:1676147. |
a brain slice superfusion system and hplc coupled to fluorometric detection were used to study depolarization-evoked release of endogenous glutamate (glu) and aspartate (asp) from substantia nigra (sn) slices. |
1991-08-01 |
2023-08-11 |
Not clear |
| G S Robertson, A Fine, H A Robertso. Dopaminergic grafts in the striatum reduce D1 but not D2 receptor-mediated rotation in 6-OHDA-lesioned rats. Brain research. vol 539. issue 2. 1991-07-31. PMID:1675908. |
fetal dopaminergic grafts in the ipsilateral substantia nigra (sn) did not augment the decreases in turning produced by concomitant ipsilateral dopaminergic grafts in the striatum in response to skf 38393. |
1991-07-31 |
2023-08-11 |
rat |
| b' J Lundgren, H Zhang, C D Agardh, M L Smith, P J Evans, B Halliwell, B K Siesj\\xc3\\xb. Acidosis-induced ischemic brain damage: are free radicals involved? Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 11. issue 4. 1991-07-25. PMID:2050747.' |
production of h2o2, estimated from the decrease in catalase activity after 3-amino-1,2,4-triazole (at) administration, was measured in the cerebral cortex, caudoputamen, hippocampus, and substantia nigra (sn) after 15 min of ischemia followed by 5, 15, and 45 min of recovery, respectively (in substantia nigra after 45 min of recovery only). |
1991-07-25 |
2023-08-11 |
rat |
| P H van Domburg, H J ten Donkelaa. The human substantia nigra and ventral tegmental area. A neuroanatomical study with notes on aging and aging diseases. Advances in anatomy, embryology, and cell biology. vol 121. 1991-07-24. PMID:2053466. |
the present study comprises a cytoarchitectonic analysis of the human substantia nigra (sn) and ventral tegmental area (vta); a discussion of their chemoarchitecture and fiber connections (mainly based on tract-tracing studies in primates) preceded by an overview of the wealth of tract-tracing data in rodents; a discussion of the involvement of the sn/vta complex in parkinson's disease (pd) and related disorders and in alzheimer's disease (ad), including some quantitative data; and finally, some functional and pathophysiological considerations, relating nigral organization to pathophysiology and hypotheses on the etiology and distribution of ad and pd. |
1991-07-24 |
2023-08-11 |
human |
| M Gupta, M H Stoler, L H Fossom, A W Tan. Tyrosine hydroxylase mRNA in the dopaminergic neurons of young adult and aged mice by in situ hybridization. Neuroscience letters. vol 119. issue 1. 1991-07-19. PMID:1982959. |
tyrosine hydroxylase (th) mrna in the dopaminergic neurons of the substantia nigra (sn) and the ventral tegmental area (vta) in young adult and aged mice was detected and quantitated using in situ hybridization. |
1991-07-19 |
2023-08-11 |
mouse |
| P M Carvey, A McRae, T F Lint, L R Ptak, E S Lo, C G Goetz, H L Klawan. The potential use of a dopamine neuron antibody and a striatal-derived neurotrophic factor as diagnostic markers in Parkinson's disease. Neurology. vol 41. issue 5 Suppl 2. 1991-07-10. PMID:2041594. |
the cerebral spinal fluid (csf) of patients with parkinson's disease (pd) contains an antibody that immunocytochemically reacts with dopamine (da) neurons in the substantia nigra (sn). |
1991-07-10 |
2023-08-11 |
Not clear |
| J P Walsh, C Cepeda, N A Buchwald, M S Levin. Neurophysiological maturation of cat substantia nigra neurons: evidence from in vitro studies. Synapse (New York, N.Y.). vol 7. issue 4. 1991-07-08. PMID:2042111. |
the membrane properties and synaptic physiology of developing cat substantia nigra (sn) neurons were studied in in vitro slice preparations. |
1991-07-08 |
2023-08-11 |
cat |
| G Bustos, J Abarca, J Fiedler, R Araned. [Neurochemistry of the mesencephalic substantia nigra: interrelations between excitatory amino acids, N-methyl-D-aspartate type receptors and intrinsic neuronal systems]. Archivos de biologia y medicina experimentales. vol 21. issue 1. 1991-05-29. PMID:2908730. |
such cortico-nigral neuronal pathway seems to functionally interact with intrinsic neuronal systems in substantia nigra (sn) by first activating different subtypes of excitatory amino acid (eaa) receptors. |
1991-05-29 |
2023-08-11 |
Not clear |
| G A Higgins, C C Jordan, M Skingl. Evidence that the unilateral activation of 5-HT1D receptors in the substantia nigra of the guinea-pig elicits contralateral rotation. British journal of pharmacology. vol 102. issue 2. 1991-05-23. PMID:1849763. |
the effects of various 5-hydroxytryptamine (5-ht) receptor agonists were examined following unilateral infusion into the substantia nigra (sn) of the guinea-pig. |
1991-05-23 |
2023-08-11 |
Not clear |
| M Santiago, H Rollema, J B de Vries, B H Westerin. Acute effects of intranigral application of MPP+ on nigral and bilateral striatal release of dopamine simultaneously recorded by microdialysis. Brain research. vol 538. issue 2. 1991-05-16. PMID:1707325. |
intracerebral microdialysis in freely moving rats was used to investigate the effects of perfusions with the 1-methyl-4-phenylpyridinium ion (mpp+) in the substantia nigra (sn) on the extracellular levels of dopamine (da), 3,4-dihydroxyphenylacetic acid (dopac), homovanillic acid (hva) and 5-hydroxyindoleacetic acid (5-hiaa) in the perfused sn and in the ipsi- and contralateral striata. |
1991-05-16 |
2023-08-11 |
rat |
| E K O'Malley, I B Black, C F Dreyfu. Local support cells promote survival of substantia nigra dopaminergic neurons in culture. Experimental neurology. vol 112. issue 1. 1991-05-14. PMID:1672852. |
to examine the regulation of neuronal survival, we have studied the substantia nigra (sn) dopaminergic (da) system, in dissociated cell culture. |
1991-05-14 |
2023-08-11 |
Not clear |
| M B Carpenter, A Jayarama. Subthalamic nucleus of the monkey: connections and immunocytochemical features of afferents. Journal fur Hirnforschung. vol 31. issue 5. 1991-05-09. PMID:1707079. |
no cells were labeled in the frontal cortex, the striatum, the substantia innominata (si), the substantia nigra (sn) or the dorsal nucleus of the raphe. |
1991-05-09 |
2023-08-11 |
monkey |
| T Uchihara, K Tsuchiya, K Kosak. Selective loss of nigral neurons in Pick's disease: a morphometric study. Acta neuropathologica. vol 81. issue 2. 1991-05-06. PMID:2082655. |
loss of neurons from the substantia nigra (sn), which is often encountered in pick's disease, was quantitatively analyzed in 13 cases of pick's disease and 19 age-matched controls. |
1991-05-06 |
2023-08-11 |
Not clear |
| C Yoshihara, N Saito, K Taniyama, C Tanak. Differential localization of four subspecies of protein kinase C in the rat striatum and substantia nigra. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 11. issue 3. 1991-04-17. PMID:1672152. |
the distribution of protein kinase c (pkc) subspecies and their colocalization with neurotransmitters were examined in the rat striatum and substantia nigra (sn), using immunocytochemistry. |
1991-04-17 |
2023-08-11 |
rat |
| N Aguila-Mansilla, B A Jorquera, W Kedzierski, J C Porte. Effect of cerebroventricular anterior pituitary grafts on in situ expression of tyrosine hydroxylase in dopaminergic neurons of the aged animal. Endocrinology. vol 128. issue 3. 1991-04-10. PMID:1671833. |
the effect of cerebroventricular anterior pituitary (ap) grafts on brain tyrosine hydroxylase (th) expression in the median eminence (me), substantia nigra (sn), and corpus striatum (cs) has been investigated in young and aged female rats. |
1991-04-10 |
2023-08-11 |
rat |
| K Ostergaard, J P Schou, J Zimme. Rat ventral mesencephalon grown as organotypic slice cultures and co-cultured with striatum, hippocampus, and cerebellum. Experimental brain research. vol 82. issue 3. 1991-04-09. PMID:1981356. |
the th immunoreactive (th-i), da neurons retained their morphological in vivo characteristics in the vm slice cultures consisting of the substantia nigra (sn) and the ventral tegmental area (vta). |
1991-04-09 |
2023-08-11 |
rat |
| U Wahnschaffe, W Lösche. Effect of selective bilateral destruction of the substantia nigra on antiepileptic drug actions in kindled rats. European journal of pharmacology. vol 186. issue 2-3. 1991-04-03. PMID:1963144. |
the substantia nigra (sn) is thought to be involved in the regulation of seizure activity and there is evidence that the nigra might be a site of anticonvulsant drug action, especially in the case of drugs that act by potentiating gamma-aminobutyric acid (gaba)-mediated neurotransmission. |
1991-04-03 |
2023-08-11 |
rat |
| C Nitsch, F Schaefe. Calcium deposits develop in rat substantia nigra but not striatum several weeks after local ibotenic acid injection. Brain research bulletin. vol 25. issue 5. 1991-04-01. PMID:2289165. |
the excitotoxin ibotenic acid (ibo) was used to place local circumscript lesions in rat substantia nigra (sn). |
1991-04-01 |
2023-08-11 |
rat |
| S Y Lu, M Giordano, A B Norman, M T Shipley, P R Sanber. Behavioral effects of neural transplants into the intact striatum. Pharmacology, biochemistry, and behavior. vol 37. issue 1. 1991-02-01. PMID:2263656. |
following bilateral transplantation of fetal cortex (ctx), substantia nigra (sn), striatum (str), or adrenal medulla (am) into the striatum, the different behavioral deficits were observed among these transplant groups. |
1991-02-01 |
2023-08-11 |
rat |
| M Sabatino, G Ferraro, N Vella, V La Grutt. Nigral influence on focal epilepsy. Neurophysiologie clinique = Clinical neurophysiology. vol 20. issue 3. 1990-12-13. PMID:2122206. |
the substantia nigra (sn) has been proposed as a structure involved in epileptiform phenomena. |
1990-12-13 |
2023-08-11 |
Not clear |