| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Magariños-Ascone, W Buño, E García-Aust. Activity in monkey substantia nigra neurons related to a simple learned movement. Experimental brain research. vol 88. issue 2. 1992-06-08. PMID:1577102. |
single cell activity was recorded in the pars compacta (snc) and pars reticulata (snr) of the substantia nigra (sn) in 4 unanesthetized macaca fascicularis to determine the motor role of the nucleus. |
1992-06-08 |
2023-08-11 |
monkey |
| H Kita, S T Kita. Intracellular study of rat globus pallidus neurons: membrane properties and responses to neostriatal, subthalamic and nigral stimulation. Brain research. vol 564. issue 2. 1992-06-04. PMID:1810628. |
the continuously firing neurons were antidromically activated by stimulation of the neostriatum (str) (23 of 68), the subthalamic nucleus (sth) (55 of 75), and the substantia nigra (sn) (25 of 46). |
1992-06-04 |
2023-08-11 |
rat |
| H F Zhou, R D Lun. Migration of astrocytes transplanted to the midbrain of neonatal rats. The Journal of comparative neurology. vol 317. issue 2. 1992-06-01. PMID:1573060. |
the highest density of cells was in the region of the substantia nigra (sn); lower numbers were found in the medial geniculate nucleus (mgn). |
1992-06-01 |
2023-08-11 |
mouse |
| D Biron, C Dauphin, T Di Paol. Effects of adrenalectomy and glucocorticoids on rat brain dopamine receptors. Neuroendocrinology. vol 55. issue 4. 1992-05-21. PMID:1314340. |
a more pronounced decrease was observed in the substantia nigra (sn) and no significant changes occurred in the anterior striatum (a.cpu), globus pallidus (gp) and accumbens (acb). |
1992-05-21 |
2023-08-11 |
rat |
| T Uchihara, H Kondo, K Kosaka, H Tsukagosh. Selective loss of nigral neurons in Alzheimer's disease: a morphometric study. Acta neuropathologica. vol 83. issue 3. 1992-05-06. PMID:1373022. |
loss of neurons from the substantia nigra (sn), which is sometimes observed in alzheimer's disease (ad), was quantitatively analyzed in 10 cases of presenile ad and 19 age-matched controls. |
1992-05-06 |
2023-08-11 |
Not clear |
| N Arai, S Yagishita, K Misugi, M Oda, K Kosaka, T Mizutani, Y Morimats. Peculiar axonal debris with subsequent astrocytic response (foamy spheroid body). A topographic, light microscopic, immunohistochemical and electron microscopic study. Virchows Archiv. A, Pathological anatomy and histopathology. vol 420. issue 3. 1992-04-24. PMID:1553816. |
fsbs were also occasionally identified in the substantia nigra (sn) and/or gp of aged persons. |
1992-04-24 |
2023-08-11 |
human |
| J O Rinn. Nigral degeneration in Parkinson's disease in relation to clinical features. Acta neurologica Scandinavica. Supplementum. vol 136. 1992-04-21. PMID:1801543. |
neuronal loss in the substantia nigra (sn) in parkinson's disease (pd) shows a topographical organisation where the lateral part of the sn is more affected. |
1992-04-21 |
2023-08-11 |
Not clear |
| V M Mann, J M Cooper, A H Schapir. Quantitation of a mitochondrial DNA deletion in Parkinson's disease. FEBS letters. vol 299. issue 3. 1992-04-16. PMID:1544498. |
a 5 kilobase deletion in mitochondrial dna (mtdna) has been reported to be responsible for the specific complex i deficiency in the substantia nigra (sn) of the parkinson's disease (pd) brain. |
1992-04-16 |
2023-08-11 |
human |
| V Leviel, B Guibert, J Mallet, N Faucon-Bigue. Induction of tyrosine hydroxylase in the rat substantia nigra by local injection of forskolin. Journal of neuroscience research. vol 30. issue 2. 1992-04-15. PMID:1686787. |
forskolin (fsk) was locally injected into the substantia nigra (sn) of anesthetised rats. |
1992-04-15 |
2023-08-11 |
rat |
| M E Hall, J M Stewar. The substance P fragment SP(1-7) stimulates motor behavior and nigral dopamine release. Pharmacology, biochemistry, and behavior. vol 41. issue 1. 1992-04-02. PMID:1371611. |
earlier studies have shown that the undecapeptide substance p (sp) alters motor behavior and dopamine metabolism following injection into the substantia nigra (sn) in rat, even though the sn appears largely devoid of sp-specific (nk-1) receptors. |
1992-04-02 |
2023-08-11 |
rat |
| M E Old. Enhanced dopamine metabolism in accumbens leads to motor activity and concurrently to increased output from nondopamine neurons in ventral tegmental area and substantia nigra. Physiology & behavior. vol 51. issue 1. 1992-03-23. PMID:1311110. |
we previously have reported that nondopamine (non-da) neurons in substantia nigra (sn) and ventral tegmental area (vta) of the rat show increased discharge rates during amphetamine (amph) and apomorphine (apo)-induced motor activity. |
1992-03-23 |
2023-08-11 |
rat |
| S Morgan, G Nomikos, J P Husto. Changes in the nigrostriatal projection associated with recovery from lesion-induced behavioral asymmetry. Behavioural brain research. vol 46. issue 2. 1992-03-23. PMID:1786123. |
rats, with 6-ohda injected into the substantia nigra (sn) on one side, were either assigned to a group with a 48-hour survival period, or one with a 15-day recovery period. |
1992-03-23 |
2023-08-11 |
rat |
| C F Baxter, C C Oh, C G Wasterlain, L K Ozaki, R A Baldwi. Alterations of GABA metabolism and seizure susceptibility in the substantia nigra of the kindled rat acclimating to changes in osmotic state. Neurochemical research. vol 16. issue 3. 1992-03-10. PMID:1780028. |
seizure susceptibility and gaba metabolism were altered in the substantia nigra [sn] of adult male sprague dawley rats when these animals were acclimating to an altered plasma osmolality. |
1992-03-10 |
2023-08-11 |
rat |
| M Mavridis, F C Colpaert, M J Milla. Differential modulation of (+)-amphetamine-induced rotation in unilateral substantia nigra-lesioned rats by alpha 1 as compared to alpha 2 agonists and antagonists. Brain research. vol 562. issue 2. 1992-03-03. PMID:1685341. |
in rats sustaining unilateral 6-hydroxy-dopamine lesions of the substantia nigra (sn), the indirect dopaminergic agonist, (+)-amphetamine (amph), dose-dependently induced robust, ipsilateral rotation: this could be dose-dependently abolished by the dopamine (d2/d1) antagonist, haloperidol. |
1992-03-03 |
2023-08-11 |
rat |
| H Nissbrandt, G Engberg, E Pilebla. The effects of GBR 12909, a dopamine re-uptake inhibitor, on monoaminergic neurotransmission in rat striatum, limbic forebrain, cortical hemispheres and substantia nigra. Naunyn-Schmiedeberg's archives of pharmacology. vol 344. issue 1. 1992-03-02. PMID:1663587. |
in order to investigate the physiological importance of the membrane pump in eliminating released dopamine (da) we have studied the effects of the putative selective dopamine re-uptake inhibitor, gbr 12909, on synthesis and metabolism of monoamines in the rat striatum, limbic forebrain, cortical hemispheres and substantia nigra (sn). |
1992-03-02 |
2023-08-11 |
rat |
| K R Melia, K Rasmussen, R Z Terwilliger, J W Haycock, E J Nestler, R S Duma. Coordinate regulation of the cyclic AMP system with firing rate and expression of tyrosine hydroxylase in the rat locus coeruleus: effects of chronic stress and drug treatments. Journal of neurochemistry. vol 58. issue 2. 1992-02-13. PMID:1345939. |
chronic (5 days) cold exposure significantly increased levels of th immunoreactivity in the lc, as previously reported, but not in substantia nigra (sn) or ventral tegmentum (vt), two dopaminergic nuclei studied for comparison. |
1992-02-13 |
2023-08-11 |
rat |
| S C Hu, F W Chang, Y J Sung, W M Hsu, E H Le. Neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the substantia nigra and the locus coeruleus in BALB/c mice. The Journal of pharmacology and experimental therapeutics. vol 259. issue 3. 1992-02-07. PMID:1684822. |
the purpose of the present study was to determine whether 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp), administered systemically or as a local infusion, has a direct neurotoxic action upon dopamine (da) neurons in the substantia nigra (sn) and norepinephrine (ne) neurons in the locus coeruleus (lc) in balb/c mice. |
1992-02-07 |
2023-08-11 |
mouse |
| A R Granata, S T Kita. Inhibitory substantia nigra inputs to the pedunculopontine neurons. Experimental brain research. vol 86. issue 3. 1992-02-07. PMID:1761086. |
responses of 43 pedunculopontine area (ppn area) neurons to electrical stimulation of the substantia nigra (sn) were studied in anesthetized rats. |
1992-02-07 |
2023-08-11 |
rat |
| G Pezzoli, A Zecchinelli, S Ricciardi, R E Burke, S Fahn, G Scarlato, A Carenz. Intraventricular infusion of epidermal growth factor restores dopaminergic pathway in hemiparkinsonian rats. Movement disorders : official journal of the Movement Disorder Society. vol 6. issue 4. 1992-02-05. PMID:1684638. |
we assessed the effect of a 35-day delayed intracerebroventricular (icv) infusion of epidermal growth factor (egf) on the survival and function of the substantia nigra (sn) dopaminergic neurons after a unilateral mechanical transection of rat nigrostriatal pathway. |
1992-02-05 |
2023-08-11 |
rat |
| A Elverfors, H Nissbrand. Reserpine-insensitive dopamine release in the substantia nigra? Brain research. vol 557. issue 1-2. 1992-01-22. PMID:1720998. |
dopamine (da) is synthesized and released not only from the terminals of the nigrostriatal dopaminergic pathway, but also from the dendrites in the substantia nigra (sn). |
1992-01-22 |
2023-08-11 |
Not clear |