| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G J Sengstock, C W Olanow, A J Dunn, G W Arendas. Iron induces degeneration of nigrostriatal neurons. Brain research bulletin. vol 28. issue 4. 1992-08-05. PMID:1617450. |
parkinson's-diseased (pd) brains have been reported to contain increased quantities of iron within the zona compacta of the substantia nigra (sn). |
1992-08-05 |
2023-08-11 |
rat |
| b' A I Piliavski\\xc4\\xad, V A Iakhintsa, N V Bulgakova, Iu P Limanski\\xc4\\xa. [Changes in background activity of periaqueductal gray neurons through application of serotonin or inhibition of its synthesis]. Neirofiziologiia = Neurophysiology. vol 24. issue 2. 1992-07-07. PMID:1534600.' |
through application of st remarkable potentiation of ba inhibition evoked by locus coeruleus (lc), substantia nigra (sn) stimulation was found, but inhibitory affects of nucleus raphe magnus (nrm) were less intensive. |
1992-07-07 |
2023-08-11 |
Not clear |
| S N Yang, W Yang, Y H Tang, S Wan. Cardiovascular effects of intracerebral injection of neuropeptide Y in rats. Zhongguo yao li xue bao = Acta pharmacologica Sinica. vol 13. issue 2. 1992-07-06. PMID:1598826. |
cardiovascular effects of microinjection of neuropeptide y (npy) (25, 50, and 100 pmol/site) into field ca3 of hippocampus (ca3), lateral septal nuclei (lsn) and substantia nigra (sn) were investigated in urethane-anesthetized rats. |
1992-07-06 |
2023-08-11 |
rat |
| N Mitra, K P Mohanakumar, D K Gangul. Dissociation of serotoninergic and dopaminergic components in acute effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. Brain research bulletin. vol 28. issue 3. 1992-06-29. PMID:1350496. |
behavioural and neurochemical effects of acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) treatment in mice have been studied in order to determine the change in the neurotransmitter profile of the following areas of the brain: substantia nigra (sn), nucleus caudatus putamen (ncp), limbic system (ls; tuberculum olfactorium and nucleus accumbens), medulla oblongata (mo) and cerebellum (cer). |
1992-06-29 |
2023-08-11 |
mouse |
| J Peris, M Coleman-Hardee, J Burry, M Pecins-Thompso. Selective changes in GABAergic transmission in substantia nigra and superior colliculus caused by ethanol and ethanol withdrawal. Alcoholism, clinical and experimental research. vol 16. issue 2. 1992-06-22. PMID:1317135. |
an increase in neuronal transmission in the gabaergic pathways from striatum to the substantia nigra (sn) and a decrease in gabaergic transmission from sn to superior colliculus (sc) both appear to play a major role in inhibiting seizure propagation. |
1992-06-22 |
2023-08-11 |
rat |
| S M Pellegrino, M J Drus. The effects of chronic ethanol consumption on the mesolimbic and nigrostriatal dopamine systems. Alcoholism, clinical and experimental research. vol 16. issue 2. 1992-06-22. PMID:1534209. |
specifically, there was a 1.6- to 2.6-fold increase in the concentration of dopac in the nucleus accumbens (na), frontal cortex (fcx), ventral tegmental area (vta), and substantia nigra (sn). |
1992-06-22 |
2023-08-11 |
rat |
| C Magariños-Ascone, W Buño, E García-Aust. Activity in monkey substantia nigra neurons related to a simple learned movement. Experimental brain research. vol 88. issue 2. 1992-06-08. PMID:1577102. |
single cell activity was recorded in the pars compacta (snc) and pars reticulata (snr) of the substantia nigra (sn) in 4 unanesthetized macaca fascicularis to determine the motor role of the nucleus. |
1992-06-08 |
2023-08-11 |
monkey |
| H Kita, S T Kita. Intracellular study of rat globus pallidus neurons: membrane properties and responses to neostriatal, subthalamic and nigral stimulation. Brain research. vol 564. issue 2. 1992-06-04. PMID:1810628. |
the continuously firing neurons were antidromically activated by stimulation of the neostriatum (str) (23 of 68), the subthalamic nucleus (sth) (55 of 75), and the substantia nigra (sn) (25 of 46). |
1992-06-04 |
2023-08-11 |
rat |
| H F Zhou, R D Lun. Migration of astrocytes transplanted to the midbrain of neonatal rats. The Journal of comparative neurology. vol 317. issue 2. 1992-06-01. PMID:1573060. |
the highest density of cells was in the region of the substantia nigra (sn); lower numbers were found in the medial geniculate nucleus (mgn). |
1992-06-01 |
2023-08-11 |
mouse |
| D Biron, C Dauphin, T Di Paol. Effects of adrenalectomy and glucocorticoids on rat brain dopamine receptors. Neuroendocrinology. vol 55. issue 4. 1992-05-21. PMID:1314340. |
a more pronounced decrease was observed in the substantia nigra (sn) and no significant changes occurred in the anterior striatum (a.cpu), globus pallidus (gp) and accumbens (acb). |
1992-05-21 |
2023-08-11 |
rat |
| T Uchihara, H Kondo, K Kosaka, H Tsukagosh. Selective loss of nigral neurons in Alzheimer's disease: a morphometric study. Acta neuropathologica. vol 83. issue 3. 1992-05-06. PMID:1373022. |
loss of neurons from the substantia nigra (sn), which is sometimes observed in alzheimer's disease (ad), was quantitatively analyzed in 10 cases of presenile ad and 19 age-matched controls. |
1992-05-06 |
2023-08-11 |
Not clear |
| N Arai, S Yagishita, K Misugi, M Oda, K Kosaka, T Mizutani, Y Morimats. Peculiar axonal debris with subsequent astrocytic response (foamy spheroid body). A topographic, light microscopic, immunohistochemical and electron microscopic study. Virchows Archiv. A, Pathological anatomy and histopathology. vol 420. issue 3. 1992-04-24. PMID:1553816. |
fsbs were also occasionally identified in the substantia nigra (sn) and/or gp of aged persons. |
1992-04-24 |
2023-08-11 |
human |
| J O Rinn. Nigral degeneration in Parkinson's disease in relation to clinical features. Acta neurologica Scandinavica. Supplementum. vol 136. 1992-04-21. PMID:1801543. |
neuronal loss in the substantia nigra (sn) in parkinson's disease (pd) shows a topographical organisation where the lateral part of the sn is more affected. |
1992-04-21 |
2023-08-11 |
Not clear |
| V M Mann, J M Cooper, A H Schapir. Quantitation of a mitochondrial DNA deletion in Parkinson's disease. FEBS letters. vol 299. issue 3. 1992-04-16. PMID:1544498. |
a 5 kilobase deletion in mitochondrial dna (mtdna) has been reported to be responsible for the specific complex i deficiency in the substantia nigra (sn) of the parkinson's disease (pd) brain. |
1992-04-16 |
2023-08-11 |
human |
| V Leviel, B Guibert, J Mallet, N Faucon-Bigue. Induction of tyrosine hydroxylase in the rat substantia nigra by local injection of forskolin. Journal of neuroscience research. vol 30. issue 2. 1992-04-15. PMID:1686787. |
forskolin (fsk) was locally injected into the substantia nigra (sn) of anesthetised rats. |
1992-04-15 |
2023-08-11 |
rat |
| M E Hall, J M Stewar. The substance P fragment SP(1-7) stimulates motor behavior and nigral dopamine release. Pharmacology, biochemistry, and behavior. vol 41. issue 1. 1992-04-02. PMID:1371611. |
earlier studies have shown that the undecapeptide substance p (sp) alters motor behavior and dopamine metabolism following injection into the substantia nigra (sn) in rat, even though the sn appears largely devoid of sp-specific (nk-1) receptors. |
1992-04-02 |
2023-08-11 |
rat |
| M E Old. Enhanced dopamine metabolism in accumbens leads to motor activity and concurrently to increased output from nondopamine neurons in ventral tegmental area and substantia nigra. Physiology & behavior. vol 51. issue 1. 1992-03-23. PMID:1311110. |
we previously have reported that nondopamine (non-da) neurons in substantia nigra (sn) and ventral tegmental area (vta) of the rat show increased discharge rates during amphetamine (amph) and apomorphine (apo)-induced motor activity. |
1992-03-23 |
2023-08-11 |
rat |
| S Morgan, G Nomikos, J P Husto. Changes in the nigrostriatal projection associated with recovery from lesion-induced behavioral asymmetry. Behavioural brain research. vol 46. issue 2. 1992-03-23. PMID:1786123. |
rats, with 6-ohda injected into the substantia nigra (sn) on one side, were either assigned to a group with a 48-hour survival period, or one with a 15-day recovery period. |
1992-03-23 |
2023-08-11 |
rat |
| C F Baxter, C C Oh, C G Wasterlain, L K Ozaki, R A Baldwi. Alterations of GABA metabolism and seizure susceptibility in the substantia nigra of the kindled rat acclimating to changes in osmotic state. Neurochemical research. vol 16. issue 3. 1992-03-10. PMID:1780028. |
seizure susceptibility and gaba metabolism were altered in the substantia nigra [sn] of adult male sprague dawley rats when these animals were acclimating to an altered plasma osmolality. |
1992-03-10 |
2023-08-11 |
rat |
| M Mavridis, F C Colpaert, M J Milla. Differential modulation of (+)-amphetamine-induced rotation in unilateral substantia nigra-lesioned rats by alpha 1 as compared to alpha 2 agonists and antagonists. Brain research. vol 562. issue 2. 1992-03-03. PMID:1685341. |
in rats sustaining unilateral 6-hydroxy-dopamine lesions of the substantia nigra (sn), the indirect dopaminergic agonist, (+)-amphetamine (amph), dose-dependently induced robust, ipsilateral rotation: this could be dose-dependently abolished by the dopamine (d2/d1) antagonist, haloperidol. |
1992-03-03 |
2023-08-11 |
rat |