| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Nissbrandt, G Engberg, E Pilebla. The effects of GBR 12909, a dopamine re-uptake inhibitor, on monoaminergic neurotransmission in rat striatum, limbic forebrain, cortical hemispheres and substantia nigra. Naunyn-Schmiedeberg's archives of pharmacology. vol 344. issue 1. 1992-03-02. PMID:1663587. |
in order to investigate the physiological importance of the membrane pump in eliminating released dopamine (da) we have studied the effects of the putative selective dopamine re-uptake inhibitor, gbr 12909, on synthesis and metabolism of monoamines in the rat striatum, limbic forebrain, cortical hemispheres and substantia nigra (sn). |
1992-03-02 |
2023-08-11 |
rat |
| K R Melia, K Rasmussen, R Z Terwilliger, J W Haycock, E J Nestler, R S Duma. Coordinate regulation of the cyclic AMP system with firing rate and expression of tyrosine hydroxylase in the rat locus coeruleus: effects of chronic stress and drug treatments. Journal of neurochemistry. vol 58. issue 2. 1992-02-13. PMID:1345939. |
chronic (5 days) cold exposure significantly increased levels of th immunoreactivity in the lc, as previously reported, but not in substantia nigra (sn) or ventral tegmentum (vt), two dopaminergic nuclei studied for comparison. |
1992-02-13 |
2023-08-11 |
rat |
| S C Hu, F W Chang, Y J Sung, W M Hsu, E H Le. Neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the substantia nigra and the locus coeruleus in BALB/c mice. The Journal of pharmacology and experimental therapeutics. vol 259. issue 3. 1992-02-07. PMID:1684822. |
the purpose of the present study was to determine whether 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp), administered systemically or as a local infusion, has a direct neurotoxic action upon dopamine (da) neurons in the substantia nigra (sn) and norepinephrine (ne) neurons in the locus coeruleus (lc) in balb/c mice. |
1992-02-07 |
2023-08-11 |
mouse |
| A R Granata, S T Kita. Inhibitory substantia nigra inputs to the pedunculopontine neurons. Experimental brain research. vol 86. issue 3. 1992-02-07. PMID:1761086. |
responses of 43 pedunculopontine area (ppn area) neurons to electrical stimulation of the substantia nigra (sn) were studied in anesthetized rats. |
1992-02-07 |
2023-08-11 |
rat |
| G Pezzoli, A Zecchinelli, S Ricciardi, R E Burke, S Fahn, G Scarlato, A Carenz. Intraventricular infusion of epidermal growth factor restores dopaminergic pathway in hemiparkinsonian rats. Movement disorders : official journal of the Movement Disorder Society. vol 6. issue 4. 1992-02-05. PMID:1684638. |
we assessed the effect of a 35-day delayed intracerebroventricular (icv) infusion of epidermal growth factor (egf) on the survival and function of the substantia nigra (sn) dopaminergic neurons after a unilateral mechanical transection of rat nigrostriatal pathway. |
1992-02-05 |
2023-08-11 |
rat |
| A Elverfors, H Nissbrand. Reserpine-insensitive dopamine release in the substantia nigra? Brain research. vol 557. issue 1-2. 1992-01-22. PMID:1720998. |
dopamine (da) is synthesized and released not only from the terminals of the nigrostriatal dopaminergic pathway, but also from the dendrites in the substantia nigra (sn). |
1992-01-22 |
2023-08-11 |
Not clear |
| P Robledo, J Fege. Acute monoaminergic depletion in the rat potentiates the excitatory effect of the subthalamic nucleus in the substantia nigra pars reticulata but not in the pallidal complex. Journal of neural transmission. General section. vol 86. issue 2. 1992-01-02. PMID:1683238. |
recent neurochemical evidence suggests that chemical or electrical stimulation of the subthalamic nucleus (sth) increases dopamine release in the substantia nigra (sn) with a subsequent decrease in the striatum. |
1992-01-02 |
2023-08-11 |
rat |
| E Stefanini, M Frau, G L Gess. Increase in D2 dopamine receptors in the substantia nigra after chronic (-)-sulpiride treatment. Brain research. vol 555. issue 2. 1991-12-23. PMID:1834311. |
changes in d2 dopamine (da) receptors in the substantia nigra (sn) and caudate nucleus (cn) homogenates were studied in rats following chronic treatment with the specific d2 receptor antagonist (-)-sulpiride (50 mg/kg s.c. twice daily for 8 days). |
1991-12-23 |
2023-08-11 |
rat |
| M Vankova, M Arluison, P A Boyer, S Bourgoin, M Quigno. Enkephalin-containing nerve cell bodies in the substantia nigra of the rat: demonstration by immunohistochemistry and in situ hybridization. Brain research bulletin. vol 27. issue 1. 1991-12-23. PMID:1933430. |
the use of a new and very sensitive immunohistochemical method, combined with intracerebral injections of colchicine, has allowed us to show that a number of nerve cell bodies immunoreactive for met-enkephalin are present in several mesencephalic nuclei of the rat, including the different subdivisions of the substantia nigra (sn). |
1991-12-23 |
2023-08-11 |
rat |
| D Ben-Shachar, M B Youdi. Intranigral iron injection induces behavioral and biochemical "parkinsonism" in rats. Journal of neurochemistry. vol 57. issue 6. 1991-12-18. PMID:1940919. |
elevated iron concentrations in the substantia nigra (sn) pars compacta have been implicated in the development of idiopathic parkinson's disease. |
1991-12-18 |
2023-08-11 |
rat |
| A Jedrzejewska, J Dymeck. Intrastriatal grafts of adrenal medulla in hemiparkinsonian rats--ultrastructural study. Acta neurobiologiae experimentalis. vol 50. issue 4-5. 1991-11-13. PMID:2130657. |
the aim of the study was to investigate the ultrastructure of the right striatum after intrastriatal adrenal medulla grafts in wistar rats with a 6-ohda unilateral lesion of the compact part of the right substantia nigra (sn). |
1991-11-13 |
2023-08-11 |
rat |
| P A Rao, P B Molinoff, J N Joyc. Ontogeny of dopamine D1 and D2 receptor subtypes in rat basal ganglia: a quantitative autoradiographic study. Brain research. Developmental brain research. vol 60. issue 2. 1991-10-21. PMID:1832594. |
the differential development of the da receptors was also evident in the substantia nigra (sn) and globus pallidus (gp). |
1991-10-21 |
2023-08-11 |
rat |
| J R Taylor, J D Elsworth, R H Roth, J R Sladek, T J Collier, D E Redmon. Grafting of fetal substantia nigra to striatum reverses behavioral deficits induced by MPTP in primates: a comparison with other types of grafts as controls. Experimental brain research. vol 85. issue 2. 1991-10-21. PMID:1893983. |
fetal substantia nigra (sn) cells were transplanted into the caudate nucleus (cn) of four vervet monkeys (cercopithecus aethiops sabaeus) that had been treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp). |
1991-10-21 |
2023-08-11 |
human |
| Z N Stowe, C B Nemerof. The electrophysiological actions of neurotensin in the central nervous system. Life sciences. vol 49. issue 14. 1991-10-17. PMID:1890928. |
nt produces a significant increase in the firing rates of individual neurons in the substantia nigra (sn), ventral tegmental area (vta), medial prefrontal cortex (mpf), hypothalamus, and periaqueductal grey (pag). |
1991-10-17 |
2023-08-11 |
Not clear |
| H J Gertz, L G Schmid. Low melanin content of substantia nigra in a case of neuroleptic malignant syndrome. Pharmacopsychiatry. vol 24. issue 3. 1991-10-16. PMID:1891487. |
histological examination of the brain revealed a low melanin content in neurons in the substantia nigra (sn). |
1991-10-16 |
2023-08-11 |
Not clear |
| Y Ichitani, H Okamura, Y Matsumoto, I Nagatsu, Y Ibat. Degeneration of the nigral dopamine neurons after 6-hydroxydopamine injection into the rat striatum. Brain research. vol 549. issue 2. 1991-10-04. PMID:1679369. |
after 2-4 weeks, a marked decrease in the number of tyrosine hydroxylase-immunoreactive neuronal perikarya and dendrites was observed in the substantia nigra (sn) ipsilateral to the injection. |
1991-10-04 |
2023-08-11 |
rat |
| J Peris, A Shawley, R Dawson, K H Abendschei. Regulation of 35S-TBPS binding by bicuculline is region specific in rat brain. Life sciences. vol 49. issue 11. 1991-09-26. PMID:1875786. |
bicuculline methiodide (bic), a gabaa antagonist, enhanced binding in cortex (ctx), substantia nigra (sn) and cerebellum (cbl), inhibited binding in inferior colliculus (ic) and did not affect binding in superior colliculus (sc). |
1991-09-26 |
2023-08-11 |
rat |
| P J Charlety, J Grenhoff, K Chergui, B De la Chapelle, M Buda, T H Svensson, G Chouve. Burst firing of mesencephalic dopamine neurons is inhibited by somatodendritic application of kynurenate. Acta physiologica Scandinavica. vol 142. issue 1. 1991-09-23. PMID:1877358. |
midbrain dopamine neurons of the zona compacta substantia nigra (sn) and ventral tegmental area (vta), giving rise to the nigrostriatal and mesolimbocortical midbrain dopamine pathways, respectively, typically display a spontaneous activity consisting of single spikes and bursts. |
1991-09-23 |
2023-08-11 |
rat |
| M Santiago, B H Westerin. Characterization and pharmacological responsiveness of dopamine release recorded by microdialysis in the substantia nigra of conscious rats. Journal of neurochemistry. vol 57. issue 3. 1991-09-04. PMID:1677674. |
the extracellular concentration of dopamine (da) and 3,4-dihydroxyphenylacetic acid in the substantia nigra (sn) and striatum was estimated by microdialysis. |
1991-09-04 |
2023-08-11 |
rat |
| N Aguila-Mansilla, W Kedzierski, J C Porte. Testicular inhibition of tyrosine hydroxylase expression in tuberoinfundibular and nigrostriatal dopaminergic neurons. Endocrinology. vol 129. issue 2. 1991-08-28. PMID:1677330. |
the arcuate-periventricular nuclei of the ventral hypothalamus were used as the source of perikarya of the tida neurons, and substantia nigra (sn) nuclei of the midbrain were used as the source of perikarya of nigrostriatal neurons. |
1991-08-28 |
2023-08-11 |
rat |