| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chen Bian, Kongjiang Zhu, Qiang Guo, Ying Xiong, Wenqin Cai, Jiqiang Zhan. Sex differences and synchronous development of steroid receptor coactivator-1 and synaptic proteins in the hippocampus of postnatal female and male C57BL/6 mice. Steroids. vol 77. issue 1-2. 2012-06-22. PMID:22085911. |
female hippocampus tended to have higher levels of src-1, syn and glur1 before p30 and psd-95 before p14; while male hippocampus have higher levels of psd-95 at p14, p60 and glur1 at p0. |
2012-06-22 |
2023-08-12 |
mouse |
| Gwendolen E Haley, Steven G Kohama, Henryk F Urbanski, Jacob Rabe. Age-related decreases in SYN levels associated with increases in MAP-2, apoE, and GFAP levels in the rhesus macaque prefrontal cortex and hippocampus. Age (Dordrecht, Netherlands). vol 32. issue 3. 2011-01-03. PMID:20640549. |
age-related decreases in syn levels associated with increases in map-2, apoe, and gfap levels in the rhesus macaque prefrontal cortex and hippocampus. |
2011-01-03 |
2023-08-12 |
mouse |
| Gwendolen E Haley, Steven G Kohama, Henryk F Urbanski, Jacob Rabe. Age-related decreases in SYN levels associated with increases in MAP-2, apoE, and GFAP levels in the rhesus macaque prefrontal cortex and hippocampus. Age (Dordrecht, Netherlands). vol 32. issue 3. 2011-01-03. PMID:20640549. |
free-floating sections from the pfc and hippocampus from adult, middle-aged, and aged rhesus macaques were immunohistochemically labeled for map-2, syn, apoe, and gfap. |
2011-01-03 |
2023-08-12 |
mouse |
| Gwendolen E Haley, Steven G Kohama, Henryk F Urbanski, Jacob Rabe. Age-related decreases in SYN levels associated with increases in MAP-2, apoE, and GFAP levels in the rhesus macaque prefrontal cortex and hippocampus. Age (Dordrecht, Netherlands). vol 32. issue 3. 2011-01-03. PMID:20640549. |
in the pfc and hippocampus of adult and middle-aged animals, the levels of syn, apoe, and gfap immunoreactivity were comparable but there was a trend towards higher map-2 levels in middle-aged than adult animals. |
2011-01-03 |
2023-08-12 |
mouse |
| Gwendolen E Haley, Steven G Kohama, Henryk F Urbanski, Jacob Rabe. Age-related decreases in SYN levels associated with increases in MAP-2, apoE, and GFAP levels in the rhesus macaque prefrontal cortex and hippocampus. Age (Dordrecht, Netherlands). vol 32. issue 3. 2011-01-03. PMID:20640549. |
there was significantly less syn and more map-2, apoe, and gfap immunoreactivity in the pfc and hippocampus of aged animals compared to adult or middle-aged animals. |
2011-01-03 |
2023-08-12 |
mouse |
| April P Neal, Kirstie H Stansfield, Paul F Worley, Richard E Thompson, Tomás R Guilart. Lead exposure during synaptogenesis alters vesicular proteins and impairs vesicular release: potential role of NMDA receptor-dependent BDNF signaling. Toxicological sciences : an official journal of the Society of Toxicology. vol 116. issue 1. 2010-10-21. PMID:20375082. |
in the current study, we show that pb(2+) exposure during synaptogenesis in cultured hippocampal neurons produces the loss of synaptophysin (syn) and synaptobrevin (syb), two proteins involved in vesicular release. |
2010-10-21 |
2023-08-12 |
Not clear |
| Xiao Ming Zhang, Shu Han, Liang Zho. [The investigation of Syn and NPY expression in brain tissues of diabetic model rat induced by streptozotocin]. Shi yan sheng wu xue bao. vol 37. issue 6. 2010-06-08. PMID:15789763. |
afterward freeze sections from the frontal cortex and hippocampus were made and stained with nissl and syn, npy immunohistochemistry staining. |
2010-06-08 |
2023-08-12 |
rat |
| Xiao Ming Zhang, Shu Han, Liang Zho. [The investigation of Syn and NPY expression in brain tissues of diabetic model rat induced by streptozotocin]. Shi yan sheng wu xue bao. vol 37. issue 6. 2010-06-08. PMID:15789763. |
both the number of neurons and the light densities of syn and npy immunostaining reaction in the frontal cortex and hippocampus of brain tissue sections significantly decreased in the diabetic model rats. |
2010-06-08 |
2023-08-12 |
rat |
| Xiao Ming Zhang, Shu Han, Liang Zho. [The investigation of Syn and NPY expression in brain tissues of diabetic model rat induced by streptozotocin]. Shi yan sheng wu xue bao. vol 37. issue 6. 2010-06-08. PMID:15789763. |
it is suggested that the decrease in neuron number and syn, npy expression in frontal cortex and hippocampus may be one of the factors leading to diabetic dementia. |
2010-06-08 |
2023-08-12 |
rat |
| Analía Reinés, Marina Cereseto, Alejandro Ferrero, Laura Sifonios, Maria Fernanda Podestá, Silvia Wikinsk. Maintenance treatment with fluoxetine is necessary to sustain normal levels of synaptic markers in an experimental model of depression: correlation with behavioral response. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 8. 2008-09-02. PMID:17955054. |
synaptophysin (syn), postsynaptic density 95 (psd-95), axon growth-associated protein 43 (gap-43), and cytoskeletal proteins (intermediate neurofilaments and map-2) were studied in the hippocampus by immunohistochemistry. |
2008-09-02 |
2023-08-12 |
Not clear |
| Feng-ying Tang, Xiong-wei Xie, Sui-yu Hu, Shuang-hong She. [Effect of BST on synapse protein SYT and SYN in the hippocampus of chronic stress depression in rats]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 31. issue 5. 2007-03-29. PMID:17062931. |
[effect of bst on synapse protein syt and syn in the hippocampus of chronic stress depression in rats]. |
2007-03-29 |
2023-08-12 |
rat |
| Feng-ying Tang, Xiong-wei Xie, Sui-yu Hu, Shuang-hong She. [Effect of BST on synapse protein SYT and SYN in the hippocampus of chronic stress depression in rats]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 31. issue 5. 2007-03-29. PMID:17062931. |
to explore the effects of baisong tablets (bst) on synapse protein synatotagmin (syt) and synaptophysin (syn) of hippocampus in chronic stress depression in rats. |
2007-03-29 |
2023-08-12 |
rat |
| Patricia Tagliaferro, Alberto Javier Ramos, Emmanuel S Onaivi, Sergio Gustavo Evrard, Javier Lujilde, Alicia Brusc. Neuronal cytoskeleton and synaptic densities are altered after a chronic treatment with the cannabinoid receptor agonist WIN 55,212-2. Brain research. vol 1085. issue 1. 2006-08-10. PMID:16566907. |
in cerebellum, there was an increase in syn expression and in the number of synaptic vesicles, while, in the hippocampus, an increase in the syn expression and in the thickness of the postsynaptic densities was observed. |
2006-08-10 |
2023-08-12 |
rat |
| Mary E McAsey, Craig Cady, Lindsay M Jackson, Miao Li, Shari Randall, Britto P Nathan, Robert G Strubl. Time course of response to estradiol replacement in ovariectomized mice: brain apolipoprotein E and synaptophysin transiently increase and glial fibrillary acidic protein is suppressed. Experimental neurology. vol 197. issue 1. 2006-02-08. PMID:16226751. |
western blotting of homogenates from somatosensory cortex, hippocampus, olfactory bulb and cerebellum was performed to obtain concentrations of glial fibrillary acidic protein (gfap), apolipoprotein e (apoe) and synaptophysin (syn). |
2006-02-08 |
2023-08-12 |
mouse |
| P Klinge, A Mühlendyck, S Lee, W Lüdemann, S Groos, M Samii, T Brinke. Temporal and regional profile of neuronal and glial cellular injury after induction of kaolin hydrocephalus. Acta neurochirurgica. Supplement. vol 81. 2003-01-21. PMID:12168325. |
after 4 or 6 weeks, global cortical gldh-activity showed further marked increases (25.7 +/- 3.9 vs. 11.3 +/- 1.5; p < 0.05), while sustained structural changes have occurred: gfap decreased in periventricular (3.3 +/- 0.5 vs. 6.3 +/- 1.2; p < 0.01), hippocampal and cortical astrocytes (0.9 +/- 0.34 vs. 5.0 +/- 0.7%; p < 0.01), whereas nf68 in cortical efferent neurones increased (6.5 +/- 1.5% vs. 4.7 +/- 0.1; p < 0.01) followed by a decrease in cortical and hippocampal (ca1) syn 38 (p < 0.05). |
2003-01-21 |
2023-08-12 |
rat |
| T D Smith, M M Adams, M Gallagher, J H Morrison, P R Rap. Circuit-specific alterations in hippocampal synaptophysin immunoreactivity predict spatial learning impairment in aged rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 17. 2000-09-28. PMID:10964964. |
postmortem analysis used a confocal laser-scanning microscopy method to quantify changes in immunofluorescence staining for the presynaptic vesicle glycoprotein, synaptophysin (syn), in the principal relays of hippocampal circuitry. |
2000-09-28 |
2023-08-12 |
human |
| G Paratcha, M L de Stein, G Szapiro, M Lopez, L Bevilaqua, M Cammarota, A P de Iraldi, I Izquierdo, J H Medin. Experience-dependent decrease in synaptically localized Fra-1. Brain research. Molecular brain research. vol 78. issue 1-2. 2000-09-25. PMID:10891591. |
here we show that the transcription factor fos-related antigen-1 (fra-1) was detected in synaptosomes (syn) and synaptic plasma membrane (spm) fractions from the rat cerebral cortex and hippocampus as a single band migrating with m(r) 42-43 kda. |
2000-09-25 |
2023-08-12 |
rat |
| R Walz, G Lenz, R Roesler, M M Vianna, V Martins, R Brentani, R Rodnight, I Izquierd. Time-dependent enhancement of inhibitory avoidance retention and MAPK activation by post-training infusion of nerve growth factor into CA1 region of hippocampus of adult rats. The European journal of neuroscience. vol 12. issue 6. 2000-08-11. PMID:10886357. |
here we investigate: (i) the effect of post-training infusion of ngf into the ca1 region of hippocampus on inhibitory avoidance (ia) retention in rats; (ii) the extension of the effect, in time and space, of ngf infusion into ca1 on the activity of mitogen-activated protein kinase (mapk, syn: erk1/2, p42/p44 mapk). |
2000-08-11 |
2023-08-12 |
rat |
| M Crispino, D J Stone, M Wei, C P Anderson, G Tocco, C E Finch, M Baudr. Variations of synaptotagmin I, synaptotagmin IV, and synaptophysin mRNA levels in rat hippocampus during the estrous cycle. Experimental neurology. vol 159. issue 2. 1999-11-19. PMID:10506530. |
mrna levels for syt1 exhibited cyclic variations in pyramidal neurons of the ca3 region of hippocampus during the estrous cycle, while mrna levels for syt4 and syn were relatively invariant in this or other regions of the hippocampus. |
1999-11-19 |
2023-08-12 |
rat |