| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wen-Guang Xia, Chan-Juan Zheng, Xuan Zhang, Juan Wan. Effects of "nourishing liver and kidney" acupuncture therapy on expression of brain derived neurotrophic factor and synaptophysin after cerebral ischemia reperfusion in rats. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 37. issue 2. 2017-06-13. PMID:28397041. |
at the each time point, the expression levels of bdnf and syn in the hippocampal regions increased significantly in the model group as compared with the sham operation group and the acupuncture control group. |
2017-06-13 |
2023-08-13 |
rat |
| Wen-Guang Xia, Chan-Juan Zheng, Xuan Zhang, Juan Wan. Effects of "nourishing liver and kidney" acupuncture therapy on expression of brain derived neurotrophic factor and synaptophysin after cerebral ischemia reperfusion in rats. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 37. issue 2. 2017-06-13. PMID:28397041. |
it was concluded that the "nourishing liver and kidney" acupuncture therapy has positive effects on behavioral recovery, as well as learning and memory abilities, probably by promoting the expression of bdnf and syn, and synaptic structure reconstruction in the ipsilateral hippocampus after i/r in rats. |
2017-06-13 |
2023-08-13 |
rat |
| Hui Li, Linjuan-Li, Yaping Wan. G-CSF improves CUMS-induced depressive behaviors through downregulating Ras/ERK/MAPK signaling pathway. Biochemical and biophysical research communications. vol 479. issue 4. 2017-06-02. PMID:27680311. |
moreover, g-csf upregulated the expression of synaptic-associated proteins including polysialylated form of neural cell adhesion molecule (psa-ncam), synaptophysin (syn), and postsynaptic density protein 95 (psd-95) in the hippocampus and g-csf significantly increased cell viability rate of hippocampal neurons in vitro. |
2017-06-02 |
2023-08-13 |
rat |
| Jianhui Liu, Yanhong Zhao, Junjun Yang, Xiaoqing Zhang, Wei Zhang, Peijun Wan. Neonatal Repeated Exposure to Isoflurane not Sevoflurane in Mice Reversibly Impaired Spatial Cognition at Juvenile-Age. Neurochemical research. vol 42. issue 2. 2017-03-07. PMID:27882447. |
the hippocampal content of n-methyl-d-aspartate receptor subunits (nmda), brain-derived neurotrophic factor (bdnf), and synaptophysin (syn) were determined by western blot. |
2017-03-07 |
2023-08-13 |
mouse |
| Lucian Medrihan, Enrico Ferrea, Barbara Greco, Pietro Baldelli, Fabio Benfenat. Asynchronous GABA Release Is a Key Determinant of Tonic Inhibition and Controls Neuronal Excitability: A Study in the Synapsin II-/- Mouse. Cerebral cortex (New York, N.Y. : 1991). vol 25. issue 10. 2016-07-20. PMID:24962993. |
we show that deletion of synapsin ii (syn ii), a presynaptic protein contributing to epilepsy predisposition in humans, leads to a loss of tonic inhibition in mouse hippocampal slices due to a dramatic decrease in presynaptic asynchronous gaba release. |
2016-07-20 |
2023-08-13 |
mouse |
| Iwona Łuszczewska-Sierakowska, Agata Wawrzyniak-Gacek, Tomasz Guz, Marcin R Tatara, Anna Charut. Morphometric Parameters of Pyramidal Cells in CA1-CA4 Fields in the Hippocampus of Arctic Fox (Vulpes lagopus). Folia biologica. vol 63. issue 4. 2016-04-08. PMID:26975141. |
the aim of the study was a quantitative examination of neurons of hippocampal subfields (ca1-ca4) in mature male arctic fox (vulpes lagopus; syn. |
2016-04-08 |
2023-08-13 |
Not clear |
| Martín Gabriel Codagnone, María Fernanda Podestá, Nonthué Alejandra Uccelli, Analía Reiné. Differential Local Connectivity and Neuroinflammation Profiles in the Medial Prefrontal Cortex and Hippocampus in the Valproic Acid Rat Model of Autism. Developmental neuroscience. vol 37. issue 3. 2016-03-29. PMID:25895486. |
at the synaptic level, while mpfc from vpa animals showed increased synaptophysin (syn) immunostaining, a syn deficit was found in all hippocampal subfields. |
2016-03-29 |
2023-08-13 |
rat |
| Elimelech Nesher, Igor Koman, Moshe Gross, Tatiana Tikhonov, Maryia Bairachnaya, Mali Salmon-Divon, Yishai Levin, Gabi Gerlitz, Izhak Michaelevski, Gal Yadid, Albert Pinhaso. Synapsin IIb as a functional marker of submissive behavior. Scientific reports. vol 5. 2016-03-28. PMID:25998951. |
we clearly show here that the expression of synapsin ii isoform b (syn iib) is constitutively upregulated in the hippocampus and striatum of submissive mice in comparison to their dominant and wild type counterparts. |
2016-03-28 |
2023-08-13 |
mouse |
| Guillermo S Moreno-Piovano, Jorgelina Varayoud, Enrique H Luque, Jorge G Ramo. Long-term ovariectomy increases BDNF gene methylation status in mouse hippocampus. The Journal of steroid biochemistry and molecular biology. vol 144 Pt B. 2014-12-22. PMID:25102255. |
in the present study, we determined whether the post-ovariectomy (post-ovx) timeframe elapsed before the initiation of chronic e treatment is critical for the estrogenic induction of neurotrophins (brain-derived neurotrophic factor, bdnf, and synaptophysin, syn) in the rodent hippocampus. |
2014-12-22 |
2023-08-13 |
mouse |
| María S García-Gutiérrez, Antonio Ortega-Álvaro, Arnau Busquets-García, Jose M Pérez-Ortiz, Laura Caltana, María Jimena Ricatti, Alicia Brusco, Rafael Maldonado, Jorge Manzanare. Synaptic plasticity alterations associated with memory impairment induced by deletion of CB2 cannabinoid receptors. Neuropharmacology. vol 73. 2014-08-13. PMID:23796670. |
map2, nf200 and synaptophysin (syn)-immunoreactive fibers were studied in the hippocampus (hip) of both genotypes. |
2014-08-13 |
2023-08-12 |
mouse |
| Fengkui Jin, Lei Li, Mei Shi, Zhenzi Li, Jinghua Zhou, Li Che. The longitudinal study of rat hippocampus influenced by stress: early adverse experience enhances hippocampal vulnerability and working memory deficit in adult rats. Behavioural brain research. vol 246. 2013-10-28. PMID:23500055. |
the expression of synaptophysin (syn) and apoptosis (apo) in hippocampal ca3 and dentate gyrus (dg) regions were examined to evaluate the effects of environmental factors on the hippocampus. |
2013-10-28 |
2023-08-12 |
rat |
| Fengkui Jin, Lei Li, Mei Shi, Zhenzi Li, Jinghua Zhou, Li Che. The longitudinal study of rat hippocampus influenced by stress: early adverse experience enhances hippocampal vulnerability and working memory deficit in adult rats. Behavioural brain research. vol 246. 2013-10-28. PMID:23500055. |
our results indicated that chronic restraint stress in early life and forced cold water swimming stress in adulthood reduced syn expression and increased apo levels in rat hippocampus, but the hippocampal damage tended to recover when rats returned to a non-stress environment. |
2013-10-28 |
2023-08-12 |
rat |
| Fengkui Jin, Lei Li, Mei Shi, Zhenzi Li, Jinghua Zhou, Li Che. The longitudinal study of rat hippocampus influenced by stress: early adverse experience enhances hippocampal vulnerability and working memory deficit in adult rats. Behavioural brain research. vol 246. 2013-10-28. PMID:23500055. |
in addition, when the rats were exposed to forced cold water swimming stress during adulthood, syn expression (ca3 and dg regions) and apo levels (ca3 region) in rat hippocampus showed statistical difference between early restraint stress group and non-early restraint stress group (rats exposed to stress in adulthood only). |
2013-10-28 |
2023-08-12 |
rat |
| Oana Toader, Nicola Forte, Marta Orlando, Enrico Ferrea, Andrea Raimondi, Pietro Baldelli, Fabio Benfenati, Lucian Medriha. Dentate gyrus network dysfunctions precede the symptomatic phase in a genetic mouse model of seizures. Frontiers in cellular neuroscience. vol 7. 2013-09-06. PMID:24009558. |
we made use of a high-resolution microelectrode array (4096 electrodes) and patch-clamp recordings, and found that in acute hippocampal slices of young pre-symptomatic (3-6 week-old) syn ii(-/-) mice excitatory synaptic output of the mossy fibers is reduced. |
2013-09-06 |
2023-08-12 |
mouse |
| Oana Toader, Nicola Forte, Marta Orlando, Enrico Ferrea, Andrea Raimondi, Pietro Baldelli, Fabio Benfenati, Lucian Medriha. Dentate gyrus network dysfunctions precede the symptomatic phase in a genetic mouse model of seizures. Frontiers in cellular neuroscience. vol 7. 2013-09-06. PMID:24009558. |
these results support the key role of the hilar mossy neurons in maintaining the normal excitability of the hippocampal network and show that the late epileptic phenotype of the syn ii(-/-) mice is preceded by neuronal circuitry dysfunctions. |
2013-09-06 |
2023-08-12 |
mouse |
| Gwendolen E Haley, Dominique H Eghlidi, Steven G Kohama, Henryk F Urbanski, Jacob Rabe. Association of microtubule associated protein-2, synaptophysin, and apolipoprotein E mRNA and protein levels with cognition and anxiety levels in aged female rhesus macaques. Behavioural brain research. vol 232. issue 1. 2012-09-27. PMID:22475553. |
map2, syn, and apoe mrna and protein levels in the prefrontal cortex (pfc), hippocampus, and amygdala, were assessed using qrt-pcr and western blot. |
2012-09-27 |
2023-08-12 |
monkey |
| Gwendolen E Haley, Dominique H Eghlidi, Steven G Kohama, Henryk F Urbanski, Jacob Rabe. Association of microtubule associated protein-2, synaptophysin, and apolipoprotein E mRNA and protein levels with cognition and anxiety levels in aged female rhesus macaques. Behavioural brain research. vol 232. issue 1. 2012-09-27. PMID:22475553. |
in the hippocampus, syn and apoe protein levels were higher in gsp than psp animals. |
2012-09-27 |
2023-08-12 |
monkey |
| Ana F B Ferreira, Caroline C Real, Alice C Rodrigues, Adilson S Alves, Luiz R G Britt. Short-term, moderate exercise is capable of inducing structural, BDNF-independent hippocampal plasticity. Brain research. vol 1425. 2012-08-13. PMID:22035567. |
in this study we used a short-term, moderate intensity treadmill exercise protocol to investigate the effects of exercise on usual markers of hippocampal synaptic and structural plasticity, such as synapsin i (syn), synaptophysin (syp), neurofilaments (nf), microtubule-associated protein 2 (map2), glutamate receptor subunits glur1 and glur2/3, brain-derived neurotrophic factor (bdnf) and glial fibrillary acidic protein (gfap). |
2012-08-13 |
2023-08-12 |
rat |
| Chen Bian, Kongjiang Zhu, Qiang Guo, Ying Xiong, Wenqin Cai, Jiqiang Zhan. Sex differences and synchronous development of steroid receptor coactivator-1 and synaptic proteins in the hippocampus of postnatal female and male C57BL/6 mice. Steroids. vol 77. issue 1-2. 2012-06-22. PMID:22085911. |
in this study, we investigated the postnatal profile of src-1 and key synaptic protein synaptophysin (syn), psd-95 and glur1 in the hippocampus of female and male mice using immunohistochemistry and western blot. |
2012-06-22 |
2023-08-12 |
mouse |
| Chen Bian, Kongjiang Zhu, Qiang Guo, Ying Xiong, Wenqin Cai, Jiqiang Zhan. Sex differences and synchronous development of steroid receptor coactivator-1 and synaptic proteins in the hippocampus of postnatal female and male C57BL/6 mice. Steroids. vol 77. issue 1-2. 2012-06-22. PMID:22085911. |
the results showed that in the female hippocampus, the highest levels of src-1 were detected at p14, syn and glur1 at p30 and psd-95 at p60; while in the males, the highest levels of src-1, syn and glur1 were detected at p30, and psd-95 at p60. |
2012-06-22 |
2023-08-12 |
mouse |