| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J L Wiley, J A Lowe, R L Balster, B R Marti. Antagonism of the discriminative stimulus effects of delta 9-tetrahydrocannabinol in rats and rhesus monkeys. The Journal of pharmacology and experimental therapeutics. vol 275. issue 1. 1995-11-21. PMID:7562536. |
this drug is the first reliable antagonist of cannabinoid discrimination and would be predicted to block or reverse cannabis intoxication in humans. |
1995-11-21 |
2023-08-12 |
rat |
| B C Paria, S K Das, S K De. The preimplantation mouse embryo is a target for cannabinoid ligand-receptor signaling. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 21. 1995-11-14. PMID:7568154. |
however, the inactive cannabinoid cannabidiol (cbd) failed to influence this response. |
1995-11-14 |
2023-08-12 |
mouse |
| G Petri, S Nyiredy, P Veszki, P Oroszlán, G Turiá. [Gas chromatographic analysis of cannabinoids on tandem columns]. Acta pharmaceutica Hungarica. vol 65. issue 3. 1995-10-24. PMID:7572186. |
the psychotropic cannabinoids delta 1-tetrahydrocannabinol (delta 1-thc) and delta 1(6)-tetrahydrocannabionol (delta 1(6)-thc), as well as, their main metabolites cannabidiol (cbd) and cannabichromene (cbc) were baseline separated except the cannabigerol (cbg) and cannabinol (cbn) pair, however for these compounds the separation was also satisfactory for the quantitative determinations. |
1995-10-24 |
2023-08-12 |
Not clear |
| A H Lichtman, K R Dimen, B R Marti. Systemic or intrahippocampal cannabinoid administration impairs spatial memory in rats. Psychopharmacology. vol 119. issue 3. 1995-10-18. PMID:7675962. |
on the other hand, neither anandamide, the putative endogenous cannabinoid ligand, nor cannabidiol, an inactive naturally occurring cannabinoid, had any apparent effects on memory. |
1995-10-18 |
2023-08-12 |
rat |
| Y Daaka, T W Klein, H Friedma. Expression of cannabinoid receptor mRNA in murine and human leukocytes. Advances in experimental medicine and biology. vol 373. 1995-10-12. PMID:7545349. |
delta 9-tetrahydrocannabinol, the major psychoactive cannabinoid of marijuana modulates immune cells in vivo and in vitro. |
1995-10-12 |
2023-08-12 |
mouse |
| R Gillan, M D Cole, A Linacre, J W Thorpe, N D Watso. Comparison of Cannabis sativa by random amplification of polymorphic DNA (RAPD) and HPLC of cannabinoids: a preliminary study. Science & justice : journal of the Forensic Science Society. vol 35. issue 3. 1995-10-11. PMID:7663991. |
comparison of cannabis sativa by random amplification of polymorphic dna (rapd) and hplc of cannabinoids: a preliminary study. |
1995-10-11 |
2023-08-12 |
Not clear |
| J M Derocq, M Ségui, J Marchand, G Le Fur, P Casella. Cannabinoids enhance human B-cell growth at low nanomolar concentrations. FEBS letters. vol 369. issue 2-3. 1995-09-22. PMID:7544292. |
the two synthetic cannabinoids, cp55,940 and win55212-2, as well as delta 9-tetrahydrocannabinol (thc), the psychoactive component of marijuana, caused a dose-dependent increase of b-cell proliferation and displayed ec50 at low nanomolar concentrations. |
1995-09-22 |
2023-08-12 |
human |
| International Symposium on Cannabis and the Cannabinoids. Proceedings. Esterel, Quebec, Canada. July 21-23, 1994. Life sciences. vol 56. issue 23-24. 1995-07-11. PMID:7776815. |
international symposium on cannabis and the cannabinoids. |
1995-07-11 |
2023-08-12 |
Not clear |
| R E Musty, P Reggio, P Consro. A review of recent advances in cannabinoid research and the 1994 International Symposium on Cannabis and the Cannabinoids. Life sciences. vol 56. issue 23-24. 1995-07-11. PMID:7776816. |
a review of recent advances in cannabinoid research and the 1994 international symposium on cannabis and the cannabinoids. |
1995-07-11 |
2023-08-12 |
Not clear |
| P H Reggio, R D Bramblett, H Yuknavich, H H Seltzman, D N Fleming, S R Fernando, L A Stevenson, R G Pertwe. The design, synthesis and testing of desoxy-CBD: further evidence for a region of steric interference at the cannabinoid receptor. Life sciences. vol 56. issue 23-24. 1995-07-11. PMID:7776828. |
cannabidiol cbd, a non-psychoactive constituent of marihuana, has been reported to possess essentially no affinity for cannabinoid cb1 receptor binding sites in the brain. |
1995-07-11 |
2023-08-12 |
mouse |
| A Abrahamov, A Abrahamov, R Mechoula. An efficient new cannabinoid antiemetic in pediatric oncology. Life sciences. vol 56. issue 23-24. 1995-07-11. PMID:7776837. |
delta-8-tetrahydrocannabinol (delta-8-thc), a cannabinoid with lower psychotropic potency than the main cannabis constituent, delta-9-tetrahydrocannabinol (delta-9-thc), was administered (18 mg/m2 in edible oil, p.o.) |
1995-07-11 |
2023-08-12 |
Not clear |
| S K Das, B C Paria, I Chakraborty, S K De. Cannabinoid ligand-receptor signaling in the mouse uterus. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 10. 1995-06-16. PMID:7753807. |
the psychoactive cannabinoid component of marijuana--delta 9-tetrahydrocannabinol (thc)--or anandamide, but not the inactive and nonpsychoactive cannabidiol (cbd), inhibited forskolin-stimulated cyclic amp formation in the mouse uterus, which was prevented by pertussis toxin pretreatment. |
1995-06-16 |
2023-08-12 |
mouse |
| V Cirimele, P Kintz, P Mangi. Testing human hair for cannabis. Forensic science international. vol 70. issue 1-3. 1995-03-17. PMID:7860029. |
to validate information on cannabis use, we investigated human hair and pubic hair for cannabinoids (thc and thc-cooh) by gas chromatography/mass spectrometry. |
1995-03-17 |
2023-08-12 |
human |
| V Cirimele, P Kintz, P Mangi. Testing human hair for cannabis. Forensic science international. vol 70. issue 1-3. 1995-03-17. PMID:7860029. |
in most cases, the highest cannabinoid concentration was found in pubic hair, suggesting that this sample may be the more suitable for cannabis testing. |
1995-03-17 |
2023-08-12 |
human |
| C A Newton, T W Klein, H Friedma. Secondary immunity to Legionella pneumophila and Th1 activity are suppressed by delta-9-tetrahydrocannabinol injection. Infection and immunity. vol 62. issue 9. 1994-09-21. PMID:8063421. |
in this report, delta 9-tetrahydrocannabinol (thc), the major psychoactive cannabinoid of marijuana and an immunomodulator, suppressed development of secondary immunity to l. pneumophila, which correlated with a reduction in th1 activity. |
1994-09-21 |
2023-08-12 |
mouse |
| R D Mattes, L M Shaw, K Engelma. Effects of cannabinoids (marijuana) on taste intensity and hedonic ratings and salivary flow of adults. Chemical senses. vol 19. issue 2. 1994-09-14. PMID:8055263. |
effects of cannabinoids (marijuana) on taste intensity and hedonic ratings and salivary flow of adults. |
1994-09-14 |
2023-08-12 |
Not clear |
| F Rodríguez de Fonseca, M A Gorriti, J J Fernández-Ruiz, T Palomo, J A Ramo. Downregulation of rat brain cannabinoid binding sites after chronic delta 9-tetrahydrocannabinol treatment. Pharmacology, biochemistry, and behavior. vol 47. issue 1. 1994-03-25. PMID:8115426. |
specific cannabinoid receptors have been recently described in extrapyramidal and limbic areas and presumably might mediate the effects of marijuana exposure on behavioral processes related to those areas. |
1994-03-25 |
2023-08-12 |
rat |
| F Rodríguez de Fonseca, M A Gorriti, J J Fernández-Ruiz, T Palomo, J A Ramo. Downregulation of rat brain cannabinoid binding sites after chronic delta 9-tetrahydrocannabinol treatment. Pharmacology, biochemistry, and behavior. vol 47. issue 1. 1994-03-25. PMID:8115426. |
in this work, we examined whether cannabinoid receptors exhibit downregulation as a consequence of the chronic exposure to delta 9-tetrahydrocannabinol (thc), which might explain certain tolerance phenomena observed in relation to motor and limbic effects of marijuana. |
1994-03-25 |
2023-08-12 |
rat |
| L M Bornheim, K Y Kim, B Chen, M A Correi. The effect of cannabidiol on mouse hepatic microsomal cytochrome P450-dependent anandamide metabolism. Biochemical and biophysical research communications. vol 197. issue 2. 1994-01-25. PMID:8267610. |
we examined whether p450 would also metabolize anandamide, and whether cannabidiol (a cannabinoid which inactivates several p450s) would affect this metabolism. |
1994-01-25 |
2023-08-12 |
mouse |
| A Oviedo, J Glowa, M Herkenha. Chronic cannabinoid administration alters cannabinoid receptor binding in rat brain: a quantitative autoradiographic study. Brain research. vol 616. issue 1-2. 1993-09-30. PMID:8395305. |
to test the hypothesis that tolerance is mediated by changes in cannabinoid receptor binding characteristics, we used quantitative in vitro autoradiography of [3h]cp-55,940 binding to striatal brain sections from rats treated either chronically or acutely with delta 9-thc, cp-55,940, or the inactive natural cannabinoid cannabidiol. |
1993-09-30 |
2023-08-12 |
rat |