| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hilary A Marusak, Joshua R B Hatfield, Moriah E Thomason, Christine A Rabina. Reduced Ventral Tegmental Area-Hippocampal Connectivity in Children and Adolescents Exposed to Early Threat. Biological psychiatry. Cognitive neuroscience and neuroimaging. vol 2. issue 2. 2019-11-20. PMID:28740870. |
here, we evaluate the impact of early threat exposure (violence, abuse) on functional connectivity of putative dopaminergic midbrain regions, the ventral tegmental area (vta) and substantia nigra (sn), giving rise to mesocorticolimbic and nigrostriatal pathways, respectively. |
2019-11-20 |
2023-08-13 |
Not clear |
| b' R Krawczyk, I Klejbor, K Turlejski, B Ludkiewicz, J Mory\\xc5\\x9. Organisation of the dopamine neuronal subsets within midbrain of the feathertail glider (Acrobates pygmaeus, Acrobatidae, Marsupialia). Folia morphologica. vol 76. issue 4. 2019-11-20. PMID:29064551.' |
due to the fact that there are no data on morphological organisation of dopaminergic system in the midbrain of this species, we decided to investigate it using immunohistochemical and quantitative methods. |
2019-11-20 |
2023-08-13 |
Not clear |
| b' R Krawczyk, I Klejbor, K Turlejski, B Ludkiewicz, J Mory\\xc5\\x9. Organisation of the dopamine neuronal subsets within midbrain of the feathertail glider (Acrobates pygmaeus, Acrobatidae, Marsupialia). Folia morphologica. vol 76. issue 4. 2019-11-20. PMID:29064551.' |
our study showed that the general distribution and characteristics of the dopaminergic cells within midbrain nuclei of the pygmy acrobat is similar to that in other species, but it lack the substantia nigra compact part - ventral tier and "tail" of the substantia nigra subnuclei. |
2019-11-20 |
2023-08-13 |
Not clear |
| b' R Krawczyk, I Klejbor, K Turlejski, B Ludkiewicz, J Mory\\xc5\\x9. Organisation of the dopamine neuronal subsets within midbrain of the feathertail glider (Acrobates pygmaeus, Acrobatidae, Marsupialia). Folia morphologica. vol 76. issue 4. 2019-11-20. PMID:29064551.' |
this study provides the first description of the dopaminergic cells and nuclei in the midbrain of the feathertail glider and we hope it will start interest in the neurobiology of this species. |
2019-11-20 |
2023-08-13 |
Not clear |
| Zade R Holloway, Timothy G Freels, Josiah F Comstock, Hunter G Nolen, Helen J Sable, Deranda B Leste. Comparing phasic dopamine dynamics in the striatum, nucleus accumbens, amygdala, and medial prefrontal cortex. Synapse (New York, N.Y.). 2019-11-20. PMID:30317673. |
midbrain dopaminergic neurons project to and modulate multiple highly interconnected modules of the basal ganglia, limbic system, and frontal cortex. |
2019-11-20 |
2023-08-13 |
mouse |
| Bing Hu, Qianqian Shi, Yu Guo, Xiyezi Diao, Heng Guo, Jinsong Zhang, Liang Yu, Hao Dai, Luonan Che. The oscillatory boundary conditions of different frequency bands in Parkinson's disease. Journal of theoretical biology. vol 451. 2019-11-18. PMID:29727632. |
the most important pathological change in pd is the degeneration and death of dopaminergic neurons in the substantia nigra of the midbrain, which results in a decrease in the dopamine (da) content of the striatum. |
2019-11-18 |
2023-08-13 |
Not clear |
| Kiana Rafiepour, Saeed Esmaeili-Mahani, Ali Salehzadeh, Vahid Sheiban. Phytohormone Abscisic Acid Protects Human Neuroblastoma SH-SY5Y Cells Against 6-Hydroxydopamine-Induced Neurotoxicity Through Its Antioxidant and Antiapoptotic Properties. Rejuvenation research. vol 22. issue 2. 2019-11-15. PMID:30091676. |
parkinson's disease (pd) is a destroying and prevalent neurodegenerative disease that is characterized by a progressive death of midbrain dopaminergic neurons. |
2019-11-15 |
2023-08-13 |
human |
| Floris G Wouterlood, Angela Engel, Mariah Daal, Gertjan Houwen, Aileen Meinderts, Tomàs Jordà Siquier, Jeroen A M Beliën, Yvette C van Dongen, Jørgen Scheel-Krüger, Anne-Marie Thierry, Henk J Groenewegen, Jean-Michel Denia. Mesencephalic dopamine neurons interfacing the shell of nucleus accumbens and the dorsolateral striatum in the rat. Journal of neuroscience research. vol 96. issue 9. 2019-11-11. PMID:29696690. |
it has previously been proposed that dopaminergic neurons in the ventral mesencephalon may play a role in this circuit interaction. |
2019-11-11 |
2023-08-13 |
rat |
| Barbara Picconi, Elvira De Leonibus, Paolo Calabres. Synaptic plasticity and levodopa-induced dyskinesia: electrophysiological and structural abnormalities. Journal of neural transmission (Vienna, Austria : 1996). vol 125. issue 8. 2019-11-04. PMID:29492662. |
parkinson's disease (pd) is a neurodegenerative disorder characterized by progressive degeneration of dopaminergic neurons located in the midbrain. |
2019-11-04 |
2023-08-13 |
Not clear |
| Mónica Tapia, Pierre Baudot, Christine Formisano-Tréziny, Martial A Dufour, Simone Temporal, Manon Lasserre, Béatrice Marquèze-Pouey, Jean Gabert, Kazuto Kobayashi, Jean-Marc Goaillar. Neurotransmitter identity and electrophysiological phenotype are genetically coupled in midbrain dopaminergic neurons. Scientific reports. vol 8. issue 1. 2019-10-28. PMID:30206240. |
neurotransmitter identity and electrophysiological phenotype are genetically coupled in midbrain dopaminergic neurons. |
2019-10-28 |
2023-08-13 |
Not clear |
| Mónica Tapia, Pierre Baudot, Christine Formisano-Tréziny, Martial A Dufour, Simone Temporal, Manon Lasserre, Béatrice Marquèze-Pouey, Jean Gabert, Kazuto Kobayashi, Jean-Marc Goaillar. Neurotransmitter identity and electrophysiological phenotype are genetically coupled in midbrain dopaminergic neurons. Scientific reports. vol 8. issue 1. 2019-10-28. PMID:30206240. |
midbrain dopaminergic (da) neurons, although quite heterogeneous, exhibit a characteristic electrical phenotype. |
2019-10-28 |
2023-08-13 |
Not clear |
| Natasa Kustrimovic, Franca Marino, Marco Cosentin. Peripheral Immunity, Immunoaging and Neuroinflammation in Parkinson's Disease. Current medicinal chemistry. vol 26. issue 20. 2019-10-25. PMID:30306855. |
parkinson's disease (pd) is the second most common neurodegenerative disorder among elderly population, characterized by the progressive degeneration of dopaminergic neurons in the midbrain. |
2019-10-25 |
2023-08-13 |
Not clear |
| Ruidong Chen, Pavel A Puzerey, Andrea C Roeser, Tori E Riccelli, Archana Podury, Kamal Maher, Alexander R Farhang, Jesse H Goldber. Songbird Ventral Pallidum Sends Diverse Performance Error Signals to Dopaminergic Midbrain. Neuron. vol 103. issue 2. 2019-10-21. PMID:31153647. |
songbird ventral pallidum sends diverse performance error signals to dopaminergic midbrain. |
2019-10-21 |
2023-08-13 |
Not clear |
| Martin Ulrich, Philipp Stauß, Georg Grö. Glucose Modulates Human Ventral Tegmental Activity in Response to Sexual Stimuli. The journal of sexual medicine. vol 15. issue 1. 2019-09-30. PMID:29289371. |
attribution of salience to sexual stimuli is mediated by the dopaminergic midbrain, including the ventral tegmental area (vta). |
2019-09-30 |
2023-08-13 |
human |
| Yu-Kai Wang, Wan-Wan Zhu, Meng-Hua Wu, Yi-Hui Wu, Zheng-Xin Liu, Ling-Min Liang, Chao Sheng, Jie Hao, Liu Wang, Wei Li, Qi Zhou, Bao-Yang H. Human Clinical-Grade Parthenogenetic ESC-Derived Dopaminergic Neurons Recover Locomotive Defects of Nonhuman Primate Models of Parkinson's Disease. Stem cell reports. vol 11. issue 1. 2019-09-30. PMID:29910127. |
here, we compared the function of clinical-grade hpesc-derived midbrain dopaminergic (da) neurons in two canonical protocols in a primate parkinson's disease (pd) model. |
2019-09-30 |
2023-08-13 |
human |
| Sonu Singh, Akanksha Mishra, Soni Jignesh Mohanbhai, Virendra Tiwari, Rajnish Kumar Chaturvedi, Sukant Khurana, Shubha Shukl. Axin-2 knockdown promote mitochondrial biogenesis and dopaminergic neurogenesis by regulating Wnt/β-catenin signaling in rat model of Parkinson's disease. Free radical biology & medicine. vol 129. 2019-09-30. PMID:30176346. |
wnts and the components of wnt/β-catenin signaling are widely expressed in midbrain and required to control the fate specification of dopaminergic (daergic) neurons, a neuronal population that specifically degenerate in parkinson's disease (pd). |
2019-09-30 |
2023-08-13 |
rat |
| Daniel Komnig, Toruntay Cem Dagli, Pardes Habib, Thomas Zeyen, Jörg B Schulz, Björn H Falkenburge. Fingolimod (FTY720) is not protective in the subacute MPTP mouse model of Parkinson's disease and does not lead to a sustainable increase of brain-derived neurotrophic factor. Journal of neurochemistry. vol 147. issue 5. 2019-09-27. PMID:30152864. |
parkinson's disease (pd) is characterized by the loss of midbrain dopaminergic neurons and aggregates of α-synuclein termed lewy bodies. |
2019-09-27 |
2023-08-13 |
mouse |
| Gerard W O'Keeffe, Aideen M Sulliva. Evidence for dopaminergic axonal degeneration as an early pathological process in Parkinson's disease. Parkinsonism & related disorders. vol 56. 2019-09-20. PMID:29934196. |
the motor symptoms manifest as a result of the progressive degeneration of midbrain dopaminergic neurons. |
2019-09-20 |
2023-08-13 |
human |
| Gerard W O'Keeffe, Aideen M Sulliva. Evidence for dopaminergic axonal degeneration as an early pathological process in Parkinson's disease. Parkinsonism & related disorders. vol 56. 2019-09-20. PMID:29934196. |
while the loss of midbrain dopaminergic neurons is well-established as being central to motor symptoms, there is an increasing focus on the timing of nigrostriatal degeneration, with preclinical evidence suggesting that early axonal degeneration may play a key role in the early stages of parkinson's disease. |
2019-09-20 |
2023-08-13 |
human |
| Gerard W O'Keeffe, Aideen M Sulliva. Evidence for dopaminergic axonal degeneration as an early pathological process in Parkinson's disease. Parkinsonism & related disorders. vol 56. 2019-09-20. PMID:29934196. |
here we review recent evidence for early midbrain dopaminergic axonal degeneration in patients with parkinson's disease, and explore the potential role of α-synuclein accumulation in this process, with a focus on studies in human populations at the imaging, post-mortem, cellular and molecular levels. |
2019-09-20 |
2023-08-13 |
human |