| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniel Gyllborg, Maqsood Ahmed, Enrique M Toledo, Spyridon Theofilopoulos, Shanzheng Yang, Charles Ffrench-Constant, Ernest Arena. The Matricellular Protein R-Spondin 2 Promotes Midbrain Dopaminergic Neurogenesis and Differentiation. Stem cell reports. vol 11. issue 3. 2019-09-19. PMID:30146491. |
the matricellular protein r-spondin 2 promotes midbrain dopaminergic neurogenesis and differentiation. |
2019-09-19 |
2023-08-13 |
mouse |
| Daniel Gyllborg, Maqsood Ahmed, Enrique M Toledo, Spyridon Theofilopoulos, Shanzheng Yang, Charles Ffrench-Constant, Ernest Arena. The Matricellular Protein R-Spondin 2 Promotes Midbrain Dopaminergic Neurogenesis and Differentiation. Stem cell reports. vol 11. issue 3. 2019-09-19. PMID:30146491. |
the development of midbrain dopaminergic (mda) neurons is controlled by multiple morphogens and transcription factors. |
2019-09-19 |
2023-08-13 |
mouse |
| Taylor S Thomas, Corey Baimel, Stephanie L Borglan. Opioid and hypocretin neuromodulation of ventral tegmental area neuronal subpopulations. British journal of pharmacology. vol 175. issue 14. 2019-09-11. PMID:28849596. |
the current view of the midbrain dopaminergic system is evolving towards a complex system of subpopulations of neurons with distinct afferent and efferent connections and, importantly, functionally different intrinsic characteristics. |
2019-09-11 |
2023-08-13 |
Not clear |
| Taylor S Thomas, Corey Baimel, Stephanie L Borglan. Opioid and hypocretin neuromodulation of ventral tegmental area neuronal subpopulations. British journal of pharmacology. vol 175. issue 14. 2019-09-11. PMID:28849596. |
instead, the midbrain dopaminergic system is now understood to be composed of anatomically and functionally heterogeneous dopaminergic subpopulations receiving specific afferent inputs and with different axonal projections. |
2019-09-11 |
2023-08-13 |
Not clear |
| Taylor S Thomas, Corey Baimel, Stephanie L Borglan. Opioid and hypocretin neuromodulation of ventral tegmental area neuronal subpopulations. British journal of pharmacology. vol 175. issue 14. 2019-09-11. PMID:28849596. |
this review will examine the distinguishing electrophysiological and neuromodulatory characteristics of the afferent and efferent connections of midbrain dopaminergic neurons. |
2019-09-11 |
2023-08-13 |
Not clear |
| Alberto Cordella, Paraskevi Krashia, Annalisa Nobili, Annabella Pignataro, Livia La Barbera, Maria Teresa Viscomi, Alessandro Valzania, Flavio Keller, Martine Ammassari-Teule, Nicola Biagio Mercuri, Nicola Berretta, Marcello D'Ameli. Dopamine loss alters the hippocampus-nucleus accumbens synaptic transmission in the Tg2576 mouse model of Alzheimer's disease. Neurobiology of disease. vol 116. 2019-09-06. PMID:29778899. |
in particular, the dopaminergic innervation from the vta to the hippocampus is critical for hippocampal-related memory function and alterations in the midbrain dopaminergic system are frequently reported in alzheimer's disease (ad), contributing to age-related decline in memory and non-cognitive functions. |
2019-09-06 |
2023-08-13 |
mouse |
| Wei Wu, Yanyin Han, Xiaoli Fan, Qinghua Li, Li Su. Protective mechanism of Wnt4 gene on Parkinson's disease (PD) transgenic Drosophila. The International journal of neuroscience. vol 129. issue 7. 2019-09-04. PMID:30526176. |
the main pathological change of parkinson's disease (pd) is progressive degeneration and necrosis of dopaminergic neurons in the midbrain, forming a lewy body in many of the remaining neurons. |
2019-09-04 |
2023-08-13 |
drosophila_melanogaster |
| Elisabeth Piccart, Christopher W Tschumi, Michael J Beckstea. Acute and subchronic PCP attenuate D2 autoreceptor signaling in substantia nigra dopamine neurons. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 29. issue 3. 2019-08-26. PMID:30686631. |
these findings suggest the effects of pcp on dopaminergic signaling in the midbrain could enhance burst firing and contribute to the development of schizophreniform behavior. |
2019-08-26 |
2023-08-13 |
Not clear |
| Francesca L'Episcopo, Cataldo Tirolo, Luca Peruzzotti-Jametti, Maria F Serapide, Nunzio Testa, Salvatore Caniglia, Beatrice Balzarotti, Stefano Pluchino, Bianca Marchett. Neural Stem Cell Grafts Promote Astroglia-Driven Neurorestoration in the Aged Parkinsonian Brain via Wnt/β-Catenin Signaling. Stem cells (Dayton, Ohio). vol 36. issue 8. 2019-08-13. PMID:29575325. |
during aging-one the most potent risk factors for parkinson's disease (pd)-both astrocytes and microglia undergo functional changes that ultimately hamper homoeostasis, defense, and repair of substantia nigra pars compacta (snpc) midbrain dopaminergic (mda) neurons. |
2019-08-13 |
2023-08-13 |
mouse |
| Yuji K Takahashi, Thomas A Stalnaker, Yasmin Marrero-Garcia, Ray M Rada, Geoffrey Schoenbau. Expectancy-Related Changes in Dopaminergic Error Signals Are Impaired by Cocaine Self-Administration. Neuron. vol 101. issue 2. 2019-08-12. PMID:30653935. |
these areas provide critical input to midbrain dopamine neurons regarding expected outcomes, suggesting that effects on learning may result from changes in dopaminergic error signaling. |
2019-08-12 |
2023-08-13 |
rat |
| Ryuhei Araki, Kazuko Hayashi, Teiji Saw. Dopamine D2-receptor Antagonist Droperidol Deepens Sevoflurane Anesthesia. Anesthesiology. vol 128. issue 4. 2019-08-06. PMID:29251645. |
although midbrain dopaminergic pathways are known to contribute to arousal and emergence from anesthesia, few reports exist regarding the anesthetic effects of dopamine d2 receptor antagonism in humans. |
2019-08-06 |
2023-08-13 |
Not clear |
| Bolton K H Chau, Huw Jarvis, Chun-Kit Law, Trevor T-J Chon. Dopamine and reward: a view from the prefrontal cortex. Behavioural pharmacology. vol 29. issue 7. 2019-08-02. PMID:30188354. |
these regions receive projections from midbrain dopamine (da) neurons and, in turn, project to other key dopaminergic regions such as the striatum. |
2019-08-02 |
2023-08-13 |
Not clear |
| Bolton K H Chau, Huw Jarvis, Chun-Kit Law, Trevor T-J Chon. Dopamine and reward: a view from the prefrontal cortex. Behavioural pharmacology. vol 29. issue 7. 2019-08-02. PMID:30188354. |
however, our current understanding of the role of da in reward-based processes is based mainly on studies of midbrain dopaminergic neurons and striatal da release from nonhuman animal models. |
2019-08-02 |
2023-08-13 |
Not clear |
| Pooja Jadiya, Snober S Mir, Aamir Nazi. Osmotic stress induced toxicity exacerbates Parkinson's associated effects via dysregulation of autophagy in transgenic C. elegans model. Cellular signalling. vol 45. 2019-07-31. PMID:29410282. |
pd, known to be associated with multiple genetic and environmental factors, is characterized by the aggregation of α-synuclein protein and loss of dopaminergic neurons in midbrain. |
2019-07-31 |
2023-08-13 |
caenorhabditis_elegans |
| Sumit Sarkar, Edward Lu, James Raymick, Joseph Hanig, Qiang G. ERK/MAP Kinase Activation is Evident in Activated Microglia of the Striatum and Substantia Nigra in an Acute and Chronically-Induced Mouse Model of Parkinson's Disease. Current neurovascular research. vol 15. issue 4. 2019-07-30. PMID:30468126. |
parkinson's disease (pd) is a debilitating, age-related disorder characterized by selective degeneration of dopaminergic neurons in the midbrain substantia nigra (snc). |
2019-07-30 |
2023-08-13 |
mouse |
| Sumit Sarkar, Edward Lu, James Raymick, Joseph Hanig, Qiang G. ERK/MAP Kinase Activation is Evident in Activated Microglia of the Striatum and Substantia Nigra in an Acute and Chronically-Induced Mouse Model of Parkinson's Disease. Current neurovascular research. vol 15. issue 4. 2019-07-30. PMID:30468126. |
dopaminergic neurons originating in the midbrain project to the striatum (caudate-putamen-cpu). |
2019-07-30 |
2023-08-13 |
mouse |
| Lifeng Qiu, Mei-Chih Liao, Allen K Chen, Shunhui Wei, Shaoping Xie, Shaul Reuveny, Zhi Dong Zhou, Walter Hunziker, Eng King Tan, Steve K W Oh, Li Zen. Immature Midbrain Dopaminergic Neurons Derived from Floor-Plate Method Improve Cell Transplantation Therapy Efficacy for Parkinson's Disease. Stem cells translational medicine. vol 6. issue 9. 2019-06-27. PMID:28650520. |
immature midbrain dopaminergic neurons derived from floor-plate method improve cell transplantation therapy efficacy for parkinson's disease. |
2019-06-27 |
2023-08-13 |
mouse |
| Petros Stathakos, Natalia Jimenez-Moreno, Lucy Crompton, Paul Nistor, Maeve A Caldwell, Jon D Lan. Imaging Autophagy in hiPSC-Derived Midbrain Dopaminergic Neuronal Cultures for Parkinson's Disease Research. Methods in molecular biology (Clifton, N.J.). vol 1880. 2019-06-24. PMID:30610703. |
imaging autophagy in hipsc-derived midbrain dopaminergic neuronal cultures for parkinson's disease research. |
2019-06-24 |
2023-08-13 |
human |
| Petros Stathakos, Natalia Jimenez-Moreno, Lucy Crompton, Paul Nistor, Maeve A Caldwell, Jon D Lan. Imaging Autophagy in hiPSC-Derived Midbrain Dopaminergic Neuronal Cultures for Parkinson's Disease Research. Methods in molecular biology (Clifton, N.J.). vol 1880. 2019-06-24. PMID:30610703. |
in pd, a class of dopaminergic neurons in the ventral midbrain (mdans) is affected. |
2019-06-24 |
2023-08-13 |
human |
| Fabiano Araújo Tofoli, Ana Teresa Silva Semeano, Ágatha Oliveira-Giacomelli, Maria Carolina Bittencourt Gonçalves, Merari F R Ferrari, Lygia Veiga Pereira, Henning Ulric. Midbrain Dopaminergic Neurons Differentiated from Human-Induced Pluripotent Stem Cells. Methods in molecular biology (Clifton, N.J.). vol 1919. 2019-06-14. PMID:30656624. |
midbrain dopaminergic neurons differentiated from human-induced pluripotent stem cells. |
2019-06-14 |
2023-08-13 |
mouse |