| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Edgar R Kramer, Birgit Lis. GDNF-Ret signaling in midbrain dopaminergic neurons and its implication for Parkinson disease. FEBS letters. vol 589. issue 24 Pt A. 2016-04-29. PMID:26555190. |
glial cell line-derived neurotrophic factor (gdnf) and its canonical receptor ret can signal together or independently to fulfill many important functions in the midbrain dopaminergic (da) system. |
2016-04-29 |
2023-08-13 |
Not clear |
| Eric J Huan. Ventral midbrain dopaminergic neurons: From neurogenesis to neurodegeneration. FEBS letters. vol 589. issue 24 Pt A. 2016-04-29. PMID:26581860. |
ventral midbrain dopaminergic neurons: from neurogenesis to neurodegeneration. |
2016-04-29 |
2023-08-13 |
Not clear |
| Mi Jin Kim, Meeyoung Park, Dae Won Kim, Min Jea Shin, Ora Son, Hyo Sang Jo, Hyeon Ji Yeo, Su Bin Cho, Jung Hwan Park, Chi Hern Lee, Duk-Soo Kim, Oh-Shin Kwon, Joon Kim, Kyu Hyung Han, Jinseu Park, Won Sik Eum, Soo Young Cho. Transduced PEP-1-PON1 proteins regulate microglial activation and dopaminergic neuronal death in a Parkinson's disease model. Biomaterials. vol 64. 2016-04-26. PMID:26117230. |
parkinson's disease (pd) is an oxidative stress-mediated neurodegenerative disorder caused by selective dopaminergic neuronal death in the midbrain substantia nigra. |
2016-04-26 |
2023-08-13 |
mouse |
| W . Glial line-derived neurotrophic factor (GDNF): Biological activities. Folia morphologica. vol 58. issue 3. 2016-04-23. PMID:14663755. |
glial cell line-derived neurotrophic factor (gdnf) was initially discovered as a neurotrophic factor that enhances survival of midbrain dopaminergic neurons. |
2016-04-23 |
2023-08-12 |
Not clear |
| Gilad Silberberg, J Paul Bola. Local and afferent synaptic pathways in the striatal microcircuitry. Current opinion in neurobiology. vol 33. 2016-04-21. PMID:26051382. |
earlier schemes of striatal connectivity presented a relatively simple architecture which included primarily excitatory input from the neocortex, dopaminergic input from the midbrain, and intrastriatal connectivity between projection neurons and a small number of interneuron types. |
2016-04-21 |
2023-08-13 |
Not clear |
| Gilad Silberberg, J Paul Bola. Local and afferent synaptic pathways in the striatal microcircuitry. Current opinion in neurobiology. vol 33. 2016-04-21. PMID:26051382. |
new afferent pathways have been discovered, as well as novel properties of previously known afferents such as the midbrain dopaminergic inputs. |
2016-04-21 |
2023-08-13 |
Not clear |
| Tilia Kimm, Zayd M Khaliq, Bruce P Bea. Differential Regulation of Action Potential Shape and Burst-Frequency Firing by BK and Kv2 Channels in Substantia Nigra Dopaminergic Neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 50. 2016-04-19. PMID:26674866. |
little is known about the voltage-dependent potassium currents underlying spike repolarization in midbrain dopaminergic neurons. |
2016-04-19 |
2023-08-13 |
mouse |
| Eva Vergaño-Vera, Eva Díaz-Guerra, Eva Rodríguez-Traver, Héctor R Méndez-Gómez, Óscar Solís, Jaime Pignatelli, James Pickel, Sang-Hun Lee, Rosario Moratalla, Carlos Vicario-Abejó. Nurr1 blocks the mitogenic effect of FGF-2 and EGF, inducing olfactory bulb neural stem cells to adopt dopaminergic and dopaminergic-GABAergic neuronal phenotypes. Developmental neurobiology. vol 75. issue 8. 2016-04-12. PMID:25447275. |
our results indicate that nurr1 overexpression in obscs induces the formation of two populations of mature dopaminergic neurons with features of the ventral mesencephalon or of the ob, capable of responding to functional dopaminergic stimuli and of releasing dopamine. |
2016-04-12 |
2023-08-13 |
mouse |
| Satoshi Ikemoto, Chen Yang, Aaron Ta. Basal ganglia circuit loops, dopamine and motivation: A review and enquiry. Behavioural brain research. vol 290. 2016-04-04. PMID:25907747. |
the other concerns circuit loops involving the cerebral cortex, basal ganglia, thalamus, epithalamus, and midbrain through which dopaminergic activity alters approach motivation. |
2016-04-04 |
2023-08-13 |
Not clear |
| Mengia-Seraina Rioult-Pedotti, Ana Pekanovic, Clement Osei Atiemo, John Marshall, Andreas Rüdiger Luf. Dopamine Promotes Motor Cortex Plasticity and Motor Skill Learning via PLC Activation. PloS one. vol 10. issue 5. 2016-04-04. PMID:25938462. |
dopaminergic neurons in the ventral tegmental area, the major midbrain nucleus projecting to the motor cortex, play a key role in motor skill learning and motor cortex synaptic plasticity. |
2016-04-04 |
2023-08-13 |
rat |
| A Rieckmann, S N Gomperts, K A Johnson, J H Growdon, K R A Van Dij. Putamen-midbrain functional connectivity is related to striatal dopamine transporter availability in patients with Lewy body diseases. NeuroImage. Clinical. vol 8. 2016-04-04. PMID:26137443. |
in line with the hypothesis that functional connectivity between the midbrain and the putamen reflects the integrity of the dopaminergic neurotransmitter system, putamen-midbrain functional connectivity was significantly correlated with striatal dat availability even after stringent control for effects of head motion. |
2016-04-04 |
2023-08-13 |
Not clear |
| Maria Vadalà, Annamaria Vallelunga, Lucia Palmieri, Beniamino Palmieri, Julio Cesar Morales-Medina, Tommaso Iannitt. Mechanisms and therapeutic applications of electromagnetic therapy in Parkinson's disease. Behavioral and brain functions : BBF. vol 11. 2016-03-30. PMID:26347217. |
parkinson's disease is a neurodegenerative pathology caused by abnormal degeneration of dopaminergic neurons in the ventral tegmental area and substantia nigra pars compacta in the midbrain resulting in damage to the basal ganglia. |
2016-03-30 |
2023-08-13 |
Not clear |
| Hsin-Yi Huang, Tsung-Lang Chiu, Hui-Fen Chang, Hui-Ru Hsu, Cheng-Yoong Pang, Hock-Kean Liew, Mei-Jen Wan. Epigenetic regulation contributes to urocortin-enhanced midbrain dopaminergic neuron differentiation. Stem cells (Dayton, Ohio). vol 33. issue 5. 2016-03-28. PMID:25641682. |
the production of midbrain dopaminergic (mda) neurons requires precise extrinsic inductive signals and intrinsic transcriptional cascade at a specific time point in development. |
2016-03-28 |
2023-08-13 |
rat |
| Willemieke M Kouwenhoven, Jesse V Veenvliet, Johannes A van Hooft, L P van der Heide, Marten P Smid. Engrailed 1 shapes the dopaminergic and serotonergic landscape through proper isthmic organizer maintenance and function. Biology open. vol 5. issue 3. 2016-03-16. PMID:26879466. |
the isthmic organizer (iso) is a signaling center that specifies the correct and distinct embryonic development of the dopaminergic midbrain and serotonergic hindbrain. |
2016-03-16 |
2023-08-13 |
mouse |
| Willemieke M Kouwenhoven, Jesse V Veenvliet, Johannes A van Hooft, L P van der Heide, Marten P Smid. Engrailed 1 shapes the dopaminergic and serotonergic landscape through proper isthmic organizer maintenance and function. Biology open. vol 5. issue 3. 2016-03-16. PMID:26879466. |
erroneous composition of dopaminergic neurons in the midbrain or serotonergic neurons in the hindbrain is associated with severe pathologies such as parkinson's disease, depression or autism. |
2016-03-16 |
2023-08-13 |
mouse |
| Willemieke M Kouwenhoven, Jesse V Veenvliet, Johannes A van Hooft, L P van der Heide, Marten P Smid. Engrailed 1 shapes the dopaminergic and serotonergic landscape through proper isthmic organizer maintenance and function. Biology open. vol 5. issue 3. 2016-03-16. PMID:26879466. |
here we investigated the role of en1 in early mid-hindbrain development, using multiple en1-ablated mouse models as well as lineage-tracing techniques, and observed the appearance of ectopic dopaminergic neurons, indistinguishable from midbrain dopaminergic neurons based on molecular profile and intrinsic electrophysiological properties. |
2016-03-16 |
2023-08-13 |
mouse |
| Li-Min Zhang, Cong-Cong Sun, Ming-Shu Mo, Luan Cen, Lei Wei, Fei-Fei Luo, Yi Li, Guo-Fei Li, Si-Yun Zhang, Li Yi, Wei Huang, Zhuo-Lin Liu, Wei-Dong Le, Ping-Yi X. Dopamine Agonists Exert Nurr1-inducing Effect in Peripheral Blood Mononuclear Cells of Patients with Parkinson's Disease. Chinese medical journal. vol 128. issue 13. 2016-03-15. PMID:26112716. |
nurr1 plays an essential role in the development, survival, and function maintenance of midbrain dopaminergic (da) neurons, and it is a potential target for parkinson's disease (pd). |
2016-03-15 |
2023-08-13 |
Not clear |
| Louise M Collins, Luc J Adriaanse, Surabhi D Theratile, Shane V Hegarty, Aideen M Sullivan, Gerard W O'Keeff. Class-IIa Histone Deacetylase Inhibition Promotes the Growth of Neural Processes and Protects Them Against Neurotoxic Insult. Molecular neurobiology. vol 51. issue 3. 2016-03-10. PMID:25065734. |
furthermore, we show that class iia-specific hdac inhibition results in activation of the canonical smad signalling pathway, which is known to promote the survival and growth of midbrain dopaminergic neurons. |
2016-03-10 |
2023-08-13 |
Not clear |
| Kana Kiyofuji, Yuki Kurauchi, Akinori Hisatsune, Takahiro Seki, Satoshi Mishima, Hiroshi Katsuk. A natural compound macelignan protects midbrain dopaminergic neurons from inflammatory degeneration via microglial arginase-1 expression. European journal of pharmacology. vol 760. 2016-03-08. PMID:25917324. |
a natural compound macelignan protects midbrain dopaminergic neurons from inflammatory degeneration via microglial arginase-1 expression. |
2016-03-08 |
2023-08-13 |
Not clear |
| Kana Kiyofuji, Yuki Kurauchi, Akinori Hisatsune, Takahiro Seki, Satoshi Mishima, Hiroshi Katsuk. A natural compound macelignan protects midbrain dopaminergic neurons from inflammatory degeneration via microglial arginase-1 expression. European journal of pharmacology. vol 760. 2016-03-08. PMID:25917324. |
compounds regulating activation profiles of microglia may provide therapeutic benefits for parkinson disease characterized by degeneration of midbrain dopaminergic neurons. |
2016-03-08 |
2023-08-13 |
Not clear |