| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fernando Caravaggio, Margaret Hahn, Shinichiro Nakajima, Philip Gerretsen, Gary Remington, Ariel Graff-Guerrer. Reduced insulin-receptor mediated modulation of striatal dopamine release by basal insulin as a possible contributing factor to hyperdopaminergia in schizophrenia. Medical hypotheses. vol 85. issue 4. 2016-07-12. PMID:26118462. |
we hypothesize that, (i) insulin receptor expression and/or function is reduced in midbrain dopamine neurons in persons with schizophrenia, (ii) basal insulin should reduce dopaminergic transmission in the striatum via these receptors, and (iii) this modulation of dopaminergic transmission by basal insulin is reduced in the brains of persons with schizophrenia. |
2016-07-12 |
2023-08-13 |
Not clear |
| Tian Tian, Zhaoming Li, Hong L. Common pathophysiology affecting diabetic retinopathy and Parkinson's disease. Medical hypotheses. vol 85. issue 4. 2016-07-12. PMID:26141638. |
parkinson's disease (pd) is a chronic progressive neurodegenerative movement disorder characterized by progressive loss of dopaminergic neurons in substantia nigra of midbrain. |
2016-07-12 |
2023-08-13 |
mouse |
| Ruth Klafke, A Alwin Prem Anand, Wolfgang Wurst, Nilima Prakash, Andrea Wizenman. Differences in the spatiotemporal expression and epistatic gene regulation of the mesodiencephalic dopaminergic precursor marker PITX3 during chicken and mouse development. Development (Cambridge, England). vol 143. issue 4. 2016-07-12. PMID:26755703. |
mesodiencephalic dopaminergic (mdda) neurons are located in the ventral mesencephalon and caudal diencephalon of all tetrapod species studied so far. |
2016-07-12 |
2023-08-13 |
mouse |
| Navid Nouri, Meera J Patel, Milan Joksimovic, Jean-Francois Poulin, Angela Anderegg, M Mark Taketo, Yong-Chao Ma, Rajeshwar Awatraman. Excessive Wnt/beta-catenin signaling promotes midbrain floor plate neurogenesis, but results in vacillating dopamine progenitors. Molecular and cellular neurosciences. vol 68. 2016-07-11. PMID:26164566. |
the midbrain fp, unlike the hindbrain and spinal cord floor plate, is highly neurogenic and produces midbrain dopaminergic (mda) neurons. |
2016-07-11 |
2023-08-13 |
Not clear |
| Laura Lahti, Maarja Haugas, Laura Tikker, Mikko Airavaara, Merja H Voutilainen, Jenni Anttila, Suman Kumar, Caisa Inkinen, Marjo Salminen, Juha Partane. Differentiation and molecular heterogeneity of inhibitory and excitatory neurons associated with midbrain dopaminergic nuclei. Development (Cambridge, England). vol 143. issue 3. 2016-07-11. PMID:26718003. |
differentiation and molecular heterogeneity of inhibitory and excitatory neurons associated with midbrain dopaminergic nuclei. |
2016-07-11 |
2023-08-13 |
Not clear |
| Laura Lahti, Maarja Haugas, Laura Tikker, Mikko Airavaara, Merja H Voutilainen, Jenni Anttila, Suman Kumar, Caisa Inkinen, Marjo Salminen, Juha Partane. Differentiation and molecular heterogeneity of inhibitory and excitatory neurons associated with midbrain dopaminergic nuclei. Development (Cambridge, England). vol 143. issue 3. 2016-07-11. PMID:26718003. |
local inhibitory gabaergic and excitatory glutamatergic neurons are important for midbrain dopaminergic and hindbrain serotonergic pathways controlling motivation, mood, and voluntary movements. |
2016-07-11 |
2023-08-13 |
Not clear |
| Goonho Park, Jieqiong Tan, Guillermina Garcia, Yunyi Kang, Guy Salvesen, Zhuohua Zhan. Regulation of Histone Acetylation by Autophagy in Parkinson Disease. The Journal of biological chemistry. vol 291. issue 7. 2016-07-06. PMID:26699403. |
here, we report that pd-related neurotoxins induce both expression and acetylation of multiple sites of histones in cultured human cells and mouse midbrain dopaminergic (da) neurons. |
2016-07-06 |
2023-08-13 |
mouse |
| Debashis Dutta, Kochupurackal P Mohanakuma. Tea and Parkinson's disease: Constituents of tea synergize with antiparkinsonian drugs to provide better therapeutic benefits. Neurochemistry international. vol 89. 2016-07-04. PMID:26271432. |
pd syndromes result from excessive loss of dopamine from the forebrain striatal region, due to dopaminergic neuronal death in the midbrain substantia nigra pars compacta. |
2016-07-04 |
2023-08-13 |
Not clear |
| Janusz W Błaszczy. Parkinson's Disease and Neurodegeneration: GABA-Collapse Hypothesis. Frontiers in neuroscience. vol 10. 2016-07-04. PMID:27375426. |
therefore, the original description of parkinson's disease (pd) as due to the selective damage of dopaminergic neurons in the mesencephalon should be updated into the concept of a severe multisystemic neurodegenerative disorder of the nervous system, whose clinical symptoms reflect the localization and progression of the most advanced gaba pathology. |
2016-07-04 |
2023-08-13 |
human |
| Ji Zhang, Beibei Yang, Hongbin Sun, Yan Zhou, Mengdi Liu, Jianhua Ding, Feng Fang, Yi Fan, Gang H. Aquaporin-4 deficiency diminishes the differential degeneration of midbrain dopaminergic neurons in experimental Parkinson's disease. Neuroscience letters. vol 614. 2016-06-29. PMID:26748031. |
aquaporin-4 deficiency diminishes the differential degeneration of midbrain dopaminergic neurons in experimental parkinson's disease. |
2016-06-29 |
2023-08-13 |
mouse |
| Leora Yetnikoff, Anita Y Cheng, Heather N Lavezzi, Kenneth P Parsley, Daniel S Zah. Sources of input to the rostromedial tegmental nucleus, ventral tegmental area, and lateral habenula compared: A study in rat. The Journal of comparative neurology. vol 523. issue 16. 2016-06-21. PMID:25940654. |
profound inhibitory control exerted on midbrain dopaminergic neurons by the lateral habenula (lhb), which has mainly excitatory outputs, is mediated by the gabaergic rostromedial tegmental nucleus (rmtg), which strongly innervates dopaminergic neurons in the ventral midbrain. |
2016-06-21 |
2023-08-13 |
rat |
| Mayur S Parmar, Juliann D Jaumotte, Michael J Zigmond, Jane E Cavanaug. ERK1, 2, and 5 expression and activation in dopaminergic brain regions during postnatal development. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 46. 2016-06-20. PMID:26363522. |
degeneration and dysfunctioning of dopaminergic neurons in the midbrain have been associated with serious neurodegenerative and neuropsychiatric disorders. |
2016-06-20 |
2023-08-13 |
Not clear |
| Meltem Hohmann, Regina Rumpel, Martin Fischer, Malte Donert, Andreas Ratzka, Alexander Klein, Maike Wesemann, Anna Effenberg, Christoph Fahlke, Claudia Groth. Electrophysiological Characterization of eGFP-Labeled Intrastriatal Dopamine Grafts. Cell transplantation. vol 24. issue 8. 2016-06-17. PMID:25199117. |
substitution of degenerated dopaminergic (da) neurons by intrastriatally transplanted ventral mesencephalon (vm)-derived progenitor cells has been shown to improve motor functions in parkinsonian patients and animal models, whereas investigations of electrophysiological properties of the grafted da neurons have been rarely performed. |
2016-06-17 |
2023-08-13 |
Not clear |
| Chuanbin Yang, Jia Zhao, Yuanyuan Cheng, X Chris Le, Jianhui Ron. N-Propargyl Caffeate Amide (PACA) Potentiates Nerve Growth Factor (NGF)-Induced Neurite Outgrowth and Attenuates 6-Hydroxydopamine (6-OHDA)-Induced Toxicity by Activating the Nrf2/HO-1 Pathway. ACS chemical neuroscience. vol 6. issue 9. 2016-06-14. PMID:26147318. |
we discovered that paca not only potentiated ngf-induced neurite outgrowth but also attenuated 6-hydroxydopamine (6-ohda) neurotoxicity in dopaminergic pc12 cells and primary rat midbrain neurons. |
2016-06-14 |
2023-08-13 |
rat |
| Yukiko Ogura, Takeshi Izumi, Mitsuhiro Yoshioka, Toshiya Matsushim. Dissociation of the neural substrates of foraging effort and its social facilitation in the domestic chick. Behavioural brain research. vol 294. 2016-06-14. PMID:26235329. |
based on zajonc's "drive theory," we hypothesized that facilitation and drive have shared neural mechanisms, and that dopaminergic projections from the midbrain to striatum are involved. |
2016-06-14 |
2023-08-13 |
chicken |
| Jonathan Murray Lovell, Judith Mylius, Henning Scheich, Michael Brosc. Stimulation of the Dopaminergic Midbrain as a Behavioral Reward in Instrumentally Conditioned Monkeys. Brain stimulation. vol 8. issue 5. 2016-06-09. PMID:26070295. |
stimulation of the dopaminergic midbrain as a behavioral reward in instrumentally conditioned monkeys. |
2016-06-09 |
2023-08-13 |
monkey |
| Guoxiang Liu, Carmelo Sgobio, Xinglong Gu, Lixin Sun, Xian Lin, Jia Yu, Loukia Parisiadou, Chengsong Xie, Namratha Sastry, Jinhui Ding, Kelly M Lohr, Gary W Miller, Yolanda Mateo, David M Lovinger, Huaibin Ca. Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic gene expression. Human molecular genetics. vol 24. issue 18. 2016-05-31. PMID:26123485. |
selective expression of parkinson's disease-related leucine-rich repeat kinase 2 g2019s missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic gene expression. |
2016-05-31 |
2023-08-13 |
mouse |
| Guoxiang Liu, Carmelo Sgobio, Xinglong Gu, Lixin Sun, Xian Lin, Jia Yu, Loukia Parisiadou, Chengsong Xie, Namratha Sastry, Jinhui Ding, Kelly M Lohr, Gary W Miller, Yolanda Mateo, David M Lovinger, Huaibin Ca. Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic gene expression. Human molecular genetics. vol 24. issue 18. 2016-05-31. PMID:26123485. |
preferential dysfunction/degeneration of midbrain substantia nigra pars compacta (snpc) dopaminergic (da) neurons contributes to the main movement symptoms manifested in parkinson's disease (pd). |
2016-05-31 |
2023-08-13 |
mouse |
| Mary Gazea, Evangelia Tasouri, Marianna Tolve, Viktoria Bosch, Anna Kabanova, Christian Gojak, Bahtiyar Kurtulmus, Orna Novikov, Joachim Spatz, Gislene Pereira, Wolfgang Hübner, Claude Brodski, Kerry L Tucker, Sandra Blaes. Primary cilia are critical for Sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain. Developmental biology. vol 409. issue 1. 2016-05-25. PMID:26542012. |
primary cilia are critical for sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain. |
2016-05-25 |
2023-08-13 |
mouse |
| Mary Gazea, Evangelia Tasouri, Marianna Tolve, Viktoria Bosch, Anna Kabanova, Christian Gojak, Bahtiyar Kurtulmus, Orna Novikov, Joachim Spatz, Gislene Pereira, Wolfgang Hübner, Claude Brodski, Kerry L Tucker, Sandra Blaes. Primary cilia are critical for Sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain. Developmental biology. vol 409. issue 1. 2016-05-25. PMID:26542012. |
midbrain dopaminergic (mda) neurons modulate various motor and cognitive functions, and their dysfunction or degeneration has been implicated in several psychiatric diseases. |
2016-05-25 |
2023-08-13 |
mouse |