| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kana Kiyofuji, Yuki Kurauchi, Akinori Hisatsune, Takahiro Seki, Satoshi Mishima, Hiroshi Katsuk. A natural compound macelignan protects midbrain dopaminergic neurons from inflammatory degeneration via microglial arginase-1 expression. European journal of pharmacology. vol 760. 2016-03-08. PMID:25917324. |
here we examined the effect of macelignan, a compound derived from nutmeg, on inflammatory degeneration of midbrain dopaminergic neurons. |
2016-03-08 |
2023-08-13 |
Not clear |
| Kana Kiyofuji, Yuki Kurauchi, Akinori Hisatsune, Takahiro Seki, Satoshi Mishima, Hiroshi Katsuk. A natural compound macelignan protects midbrain dopaminergic neurons from inflammatory degeneration via microglial arginase-1 expression. European journal of pharmacology. vol 760. 2016-03-08. PMID:25917324. |
treatment of midbrain slice cultures with interferon (ifn)-γ and lipopolysaccharide (lps) caused a substantial decrease in viable dopaminergic neurons and an increase in nitric oxide (no) production indicated by extracellular nitrite accumulation. |
2016-03-08 |
2023-08-13 |
Not clear |
| S Ma, A L Gundlac. Ascending control of arousal and motivation: role of nucleus incertus and its peptide neuromodulators in behavioural responses to stress. Journal of neuroendocrinology. vol 27. issue 6. 2016-03-01. PMID:25612218. |
established modulators of arousal include the cholinergic, serotonergic, noradrenergic and dopaminergic networks originating in the pons and midbrain. |
2016-03-01 |
2023-08-13 |
Not clear |
| Ashwin G Ramayya, Isaac Pedisich, Michael J Kahan. Expectation modulates neural representations of valence throughout the human brain. NeuroImage. vol 115. 2016-02-29. PMID:25937489. |
using high-frequency activity (hfa, 70-200 hz) as an indicator of local firing rates, we found that expectation modulated reward-related neural activity in widespread brain regions, including regions that receive sparse inputs from midbrain dopaminergic neurons. |
2016-02-29 |
2023-08-13 |
human |
| Puja K Parekh, Angela R Ozburn, Colleen A McClun. Circadian clock genes: effects on dopamine, reward and addiction. Alcohol (Fayetteville, N.Y.). vol 49. issue 4. 2016-02-23. PMID:25641765. |
in this review, we will discuss how circadian genes can regulate midbrain dopaminergic activity and subsequently, drug intake and reward. |
2016-02-23 |
2023-08-13 |
Not clear |
| Iva Stojkovska, Brandon M Wagner, Brad E Morriso. Parkinson's disease and enhanced inflammatory response. Experimental biology and medicine (Maywood, N.J.). vol 240. issue 11. 2016-02-23. PMID:25769314. |
the clinical symptoms of pd result from a loss of midbrain dopaminergic (da) neurons. |
2016-02-23 |
2023-08-13 |
Not clear |
| D Caudal, A Alvarsson, A Björklund, P Svenningsso. Depressive-like phenotype induced by AAV-mediated overexpression of human α-synuclein in midbrain dopaminergic neurons. Experimental neurology. vol 273. 2016-02-18. PMID:26363495. |
depressive-like phenotype induced by aav-mediated overexpression of human α-synuclein in midbrain dopaminergic neurons. |
2016-02-18 |
2023-08-13 |
human |
| Julia Spaniol, Holly J Bowen, Pete Wegier, Cheryl Grad. Neural responses to monetary incentives in younger and older adults. Brain research. vol 1612. 2016-02-16. PMID:25305570. |
reward anticipation is associated with activity in the dopaminergic midbrain as well as the ventral striatum, amygdala, and medial prefrontal cortex. |
2016-02-16 |
2023-08-13 |
Not clear |
| Emmanouil Metzakopian, Kamal Bouhali, Matías Alvarez-Saavedra, Jeffrey A Whitsett, David J Picketts, Siew-Lan An. Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells. Development (Cambridge, England). vol 142. issue 7. 2016-02-13. PMID:25804738. |
furthermore, the chromatin remodelling factor smarca1 was shown to function downstream of foxa1 and foxa2 to regulate differentiation from immature to mature midbrain dopaminergic neurons. |
2016-02-13 |
2023-08-13 |
mouse |
| Stefan Jean-Pierre Haas, Xiaolai Zhou, Venissa Machado, Andreas Wree, Kerstin Krieglstein, Björn Spitta. Expression of Tgfβ1 and Inflammatory Markers in the 6-hydroxydopamine Mouse Model of Parkinson's Disease. Frontiers in molecular neuroscience. vol 9. 2016-02-12. PMID:26869879. |
parkinson's disease (pd) is a neurodegenerative disorder that is characterized by loss of midbrain dopaminergic (mda) neurons in the substantia nigra (sn). |
2016-02-12 |
2023-08-13 |
mouse |
| Lance M Villeneuve, Phillip R Purnell, Kelly L Stauch, Howard S Fo. Neonatal mitochondrial abnormalities due to PINK1 deficiency: Proteomics reveals early changes relevant to Parkinson׳s disease. Data in brief. vol 6. 2016-02-11. PMID:26866053. |
our findings demonstrated pink1-deficient rats at 4 months of age had mitochondrial proteomic and functional abnormalities before the onset of parkinsonian symptoms (6 months) such as the movement disorder, loss of midbrain dopaminergic neurons, or the progressive degeneration present at 9 months. |
2016-02-11 |
2023-08-13 |
rat |
| Sybren F de Kloet, Huibert D Mansvelder, Taco J De Vrie. Cholinergic modulation of dopamine pathways through nicotinic acetylcholine receptors. Biochemical pharmacology. vol 97. issue 4. 2016-02-09. PMID:26208783. |
profound modulatory cholinergic input from the pedunculopontine and laterodorsal tegmentum to dopaminergic midbrain nuclei as well as local cholinergic interneuron projections to dopamine neuron axons in the striatum may play a major role in the effects of nicotine. |
2016-02-09 |
2023-08-13 |
Not clear |
| Anne-Marike Schiffer, Florian Waszak, Nick Yeun. The role of prediction and outcomes in adaptive cognitive control. Journal of physiology, Paris. vol 109. issue 1-3. 2016-02-08. PMID:25698177. |
the model lastly envisages a role for hierarchical projections from the striatum to dopaminergic midbrain areas that enable more rostral frontal areas to bias the selection of inputs from more posterior frontal areas via their respective representations in the basal ganglia. |
2016-02-08 |
2023-08-13 |
human |
| Hideyuki Sawada, Tomoko Oeda, Kenji Yamamot. Catecholamines and Neurodegeneration in Parkinson's Disease-From Diagnostic Marker to Aggregations of α-Synuclein. Diagnostics (Basel, Switzerland). vol 3. issue 2. 2016-02-03. PMID:26835675. |
it is characterized by midbrain dopaminergic neuronal degeneration accompanied by lewy bodies, intra-cytoplasmic neuronal inclusions that consist mainly of alpha-synuclein. |
2016-02-03 |
2023-08-13 |
Not clear |
| Kristoffer Carl Aberg, Kimberly C Doell, Sophie Schwart. Hemispheric Asymmetries in Striatal Reward Responses Relate to Approach-Avoidance Learning and Encoding of Positive-Negative Prediction Errors in Dopaminergic Midbrain Regions. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 43. 2016-02-02. PMID:26511241. |
hemispheric asymmetries in striatal reward responses relate to approach-avoidance learning and encoding of positive-negative prediction errors in dopaminergic midbrain regions. |
2016-02-02 |
2023-08-13 |
human |
| Kristoffer Carl Aberg, Kimberly C Doell, Sophie Schwart. Hemispheric Asymmetries in Striatal Reward Responses Relate to Approach-Avoidance Learning and Encoding of Positive-Negative Prediction Errors in Dopaminergic Midbrain Regions. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 43. 2016-02-02. PMID:26511241. |
moreover, using a computational modeling approach, we demonstrate that better encoding of positive (vs negative) pes in dopaminergic midbrain regions is associated with better approach (vs avoidance) learning, specifically in participants with larger reward responses in the left (vs right) ventral striatum. |
2016-02-02 |
2023-08-13 |
human |
| Alexander A Nevue, Cameron J Elde, David J Perkel, Christine V Portfor. Dopaminergic Input to the Inferior Colliculus in Mice. Frontiers in neuroanatomy. vol 9. 2016-02-02. PMID:26834578. |
the principal auditory midbrain nucleus, the inferior colliculus (ic), is a likely location for dopaminergic modulation of auditory processing because it contains dopamine receptors and nerve terminals immunoreactive for tyrosine hydroxylase (th), the rate-limiting enzyme in dopamine synthesis. |
2016-02-02 |
2023-08-13 |
mouse |
| Agnes Norbury, Masud Husai. Sensation-seeking: Dopaminergic modulation and risk for psychopathology. Behavioural brain research. vol 288. 2016-01-27. PMID:25907745. |
both high tonic dopamine levels and hyper-reactive midbrain dopaminergic responses to signals of forthcoming reward are evident in higher sensations-seekers. |
2016-01-27 |
2023-08-13 |
human |
| Adelin Gustot, José Ignacio Gallea, Rabia Sarroukh, María Soledad Celej, Jean-Marie Ruysschaert, Vincent Raussen. Amyloid fibrils are the molecular trigger of inflammation in Parkinson's disease. The Biochemical journal. vol 471. issue 3. 2016-01-25. PMID:26272943. |
parkinson's disease (pd) is an age-related movement disorder characterized by a progressive degeneration of dopaminergic neurons in the midbrain. |
2016-01-25 |
2023-08-13 |
Not clear |
| Edgar R Krame. The neuroprotective and regenerative potential of parkin and GDNF/Ret signaling in the midbrain dopaminergic system. Neural regeneration research. vol 10. issue 11. 2016-01-25. PMID:26807104. |
the neuroprotective and regenerative potential of parkin and gdnf/ret signaling in the midbrain dopaminergic system. |
2016-01-25 |
2023-08-13 |
Not clear |