| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Biswarup Ghosh, Chen Zhang, George M Smit. Bridging between transplantation therapy and neurotrophic factors in Parkinson's disease. Frontiers in bioscience (Elite edition). vol 6. 2014-08-25. PMID:24896204. |
with increased understanding of growth and guidance molecule effecting dopaminergic neurons, it may be feasible to place transplants in the damaged substantia nigra and direct the growth of axons into target regions to reconstruction of midbrain dopamine (da) circuitry. |
2014-08-25 |
2023-08-13 |
Not clear |
| Doan V Khanh, Yun-Hee Choi, Sang Hyun Moh, Ann W Kinyua, Ki Woo Ki. Leptin and insulin signaling in dopaminergic neurons: relationship between energy balance and reward system. Frontiers in psychology. vol 5. 2014-08-22. PMID:25147530. |
recent studies have indicated the midbrain dopaminergic neurons as a potential site for leptin' and insulin's actions on mediating the feeding behaviors and therefore affecting the energy balance. |
2014-08-22 |
2023-08-13 |
Not clear |
| Doan V Khanh, Yun-Hee Choi, Sang Hyun Moh, Ann W Kinyua, Ki Woo Ki. Leptin and insulin signaling in dopaminergic neurons: relationship between energy balance and reward system. Frontiers in psychology. vol 5. 2014-08-22. PMID:25147530. |
this review therefore describes the convergence of energy regulation and reward system, particularly focusing on leptin and insulin signaling in the midbrain dopaminergic neurons. |
2014-08-22 |
2023-08-13 |
Not clear |
| Kanwar Virdee, Simon McArthur, Frédéric Brischoux, Daniele Caprioli, Mark A Ungless, Trevor W Robbins, Jeffrey W Dalley, Glenda E Gillie. Antenatal glucocorticoid treatment induces adaptations in adult midbrain dopamine neurons, which underpin sexually dimorphic behavioral resilience. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 2. 2014-08-21. PMID:23929547. |
we demonstrated previously that antenatal glucocorticoid treatment (agt, gestational days 16-19) altered the size and organization of the adult rat midbrain dopaminergic (da) populations. |
2014-08-21 |
2023-08-12 |
rat |
| Daniel C Berwick, Kirsten Harve. The regulation and deregulation of Wnt signaling by PARK genes in health and disease. Journal of molecular cell biology. vol 6. issue 1. 2014-08-21. PMID:24115276. |
recent work has established a critical role for these pathways in brain development, especially of midbrain dopaminergic neurones. |
2014-08-21 |
2023-08-12 |
Not clear |
| Daniel C Berwick, Kirsten Harve. The regulation and deregulation of Wnt signaling by PARK genes in health and disease. Journal of molecular cell biology. vol 6. issue 1. 2014-08-21. PMID:24115276. |
this debilitating disease is characterized by the progressive loss of a subset of midbrain dopaminergic neurones in the substantia nigra leading to typical extrapyramidal motor symptoms. |
2014-08-21 |
2023-08-12 |
Not clear |
| Milan Joksimovic, Rajeshwar Awatraman. Wnt/β-catenin signaling in midbrain dopaminergic neuron specification and neurogenesis. Journal of molecular cell biology. vol 6. issue 1. 2014-08-21. PMID:24287202. |
loss of midbrain dopaminergic (mda) neurons underlies the motor symptoms of parkinson's disease. |
2014-08-21 |
2023-08-12 |
Not clear |
| Ernest Arena. Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease. Journal of molecular cell biology. vol 6. issue 1. 2014-08-21. PMID:24431302. |
wnt signaling regulates multiple cellular functions and cell systems, including the development and maintenance of midbrain dopaminergic (mda) neurons. |
2014-08-21 |
2023-08-12 |
Not clear |
| Francesca L'Episcopo, Cataldo Tirolo, Salvo Caniglia, Nuccio Testa, Maria Concetta Morale, Maria Francesca Serapide, Stefano Pluchino, Bianca Marchett. Targeting Wnt signaling at the neuroimmune interface for dopaminergic neuroprotection/repair in Parkinson's disease. Journal of molecular cell biology. vol 6. issue 1. 2014-08-21. PMID:24431301. |
accumulating evidence points to a dysregulation of wnt signaling in major neurodegenerative pathologies including parkinson's disease (pd), a common neurodegenerative disorder characterized by the progressive loss of midbrain dopaminergic (mda) neurons and deregulated activation of astrocytes and microglia. |
2014-08-21 |
2023-08-12 |
Not clear |
| Angela Anderegg, Hsin-Pin Lin, Jun-An Chen, Giuliana Caronia-Brown, Natalya Cherepanova, Beth Yun, Milan Joksimovic, Jason Rock, Brian D Harfe, Randy Johnson, Rajeshwar Awatraman. An Lmx1b-miR135a2 regulatory circuit modulates Wnt1/Wnt signaling and determines the size of the midbrain dopaminergic progenitor pool. PLoS genetics. vol 9. issue 12. 2014-08-20. PMID:24348261. |
an lmx1b-mir135a2 regulatory circuit modulates wnt1/wnt signaling and determines the size of the midbrain dopaminergic progenitor pool. |
2014-08-20 |
2023-08-12 |
Not clear |
| Sunayana B Banerjee, Brian G Dias, David Crews, Elizabeth Adkins-Rega. Newly paired zebra finches have higher dopamine levels and immediate early gene Fos expression in dopaminergic neurons. The European journal of neuroscience. vol 38. issue 12. 2014-08-15. PMID:24329731. |
in the present study, we sought to understand the specific contribution to pair formation in zebra finches of the mesolimbic dopaminergic pathway that projects from the midbrain ventral tegmental area to the nucleus accumbens. |
2014-08-15 |
2023-08-12 |
Not clear |
| Kai-Hsiang Kang, Horng-Hui Liou, Mann-Jen Hour, Houng-Chi Liou, Wen-Mei F. Protection of dopaminergic neurons by 5-lipoxygenase inhibitor. Neuropharmacology. vol 73. 2014-08-13. PMID:23800665. |
in this study, we investigated the effect of the pharmacological inhibition of 5-lipoxygenase on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)/mpp(+)-induced dopaminergic neuronal death in midbrain neuron-glia co-cultures and in mice. |
2014-08-13 |
2023-08-12 |
mouse |
| Kai-Hsiang Kang, Horng-Hui Liou, Mann-Jen Hour, Houng-Chi Liou, Wen-Mei F. Protection of dopaminergic neurons by 5-lipoxygenase inhibitor. Neuropharmacology. vol 73. 2014-08-13. PMID:23800665. |
mk-886, a specific inhibitor of 5-lox activating protein (flap), significantly increased [(3)h]-dopamine uptake, a functional indicator of the integrity of dopaminergic neurons, in midbrain cultures or the sh-sy5y human dopaminergic cell line following mpp(+) treatment. |
2014-08-13 |
2023-08-12 |
mouse |
| Pia Jensen, Michel Heimberg, Angelique D Ducray, Hans R Widmer, Morten Meye. Expression of trefoil factor 1 in the developing and adult rat ventral mesencephalon. PloS one. vol 8. issue 10. 2014-08-02. PMID:24116124. |
in conclusion, we show for the first time that distinct subpopulations of midbrain dopaminergic neurons express tff1, and that this expression pattern is altered in a rat model of parkinson's disease. |
2014-08-02 |
2023-08-12 |
rat |
| Mickael Decressac, Nikolaos Volakakis, Anders Björklund, Thomas Perlman. NURR1 in Parkinson disease--from pathogenesis to therapeutic potential. Nature reviews. Neurology. vol 9. issue 11. 2014-07-28. PMID:24126627. |
in parkinson disease (pd), affected midbrain dopamine (da) neurons lose specific dopaminergic properties before the neurons die. |
2014-07-28 |
2023-08-12 |
Not clear |
| Carla Pais Fonseca, Susana Gama, Ana Saavedra, Graça Baltaza. H2O2- or l-DOPA-injured dopaminergic neurons trigger the release of soluble mediators that up-regulate striatal GDNF through different signalling pathways. Biochimica et biophysica acta. vol 1842. issue 7. 2014-07-24. PMID:24632468. |
we have previously shown that h2o2- or l-3,4-dihydroxyphenylalanine (l-dopa)-challenged dopaminergic neurons trigger the release of soluble factors that signal ventral midbrain astrocytes to increase gdnf expression. |
2014-07-24 |
2023-08-12 |
Not clear |
| Saeed Esmaeili-Mahani, Somayeh Vazifekhah, Hamzeh Pasban-Aliabadi, Mehdi Abbasnejad, Vahid Sheiban. Protective effect of orexin-A on 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y human dopaminergic neuroblastoma cells. Neurochemistry international. vol 63. issue 8. 2014-07-22. PMID:24135219. |
parkinson's disease (pd) is a progressive neurodegenerative disease characterized by progressive and selective death of midbrain dopaminergic neurons. |
2014-07-22 |
2023-08-12 |
human |
| Celia van der Merwe, Ben Loos, Chrisna Swart, Craig Kinnear, Franclo Henning, Lize van der Merwe, Komala Pillay, Nolan Muller, Dan Zaharie, Lize Engelbrecht, Jonathan Carr, Soraya Bardie. Mitochondrial impairment observed in fibroblasts from South African Parkinson's disease patients with parkin mutations. Biochemical and biophysical research communications. vol 447. issue 2. 2014-07-22. PMID:24721425. |
parkinson's disease (pd), defined as a neurodegenerative disorder, is characterized by the loss of dopaminergic neurons in the substantia nigra in the midbrain. |
2014-07-22 |
2023-08-13 |
Not clear |
| Chenere P Ramsey, Malú G Tanse. A survey from 2012 of evidence for the role of neuroinflammation in neurotoxin animal models of Parkinson's disease and potential molecular targets. Experimental neurology. vol 256. 2014-07-10. PMID:23726958. |
parkinson's disease (pd) is a neurodegenerative movement disorder that results from the progressive loss of dopaminergic neurons in the midbrain substantia nigra pars compacta (snpc). |
2014-07-10 |
2023-08-12 |
Not clear |
| Hai-Kang Zhao, Bao-Ying Chen, Rui Chang, Jian-Bang Wang, Feng Ni, Lei Yang, Xi-Chao Dong, Shu-Hu Sun, Ge Zhao, Wei Fang, Quan-Rui Ma, Xue-Lian Wang, Jun Y. Vasonatrin peptide, a novel protector of dopaminergic neurons against the injuries induced by n-methyl-4-phenylpyridiniums. Peptides. vol 49. 2014-07-07. PMID:24055805. |
here, cultured dopaminergic neurons from ventral mesencephalon of mouse were exposed to n-methyl-4-phenylpyridinium (mpp(+)), and the effects of vnp on the neurotoxicity of mpp(+) were investigated. |
2014-07-07 |
2023-08-12 |
mouse |