| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dione Y L Quek, Natasha Taylor, Moran Gilat, Simon J G Lewis, Kaylena A Ehgoetz Marten. Effect of dopamine on limbic network connectivity at rest in Parkinson's disease patients with freezing of gait. Translational neuroscience. vol 15. issue 1. 2024-05-06. PMID:38708096. |
while other studies found that dopaminergic replacement therapy alters functional brain organization in pd, the specific effect of dopamine medication on fronto-striato-limbic functional connectivity in freezers remains unclear. |
2024-05-06 |
2024-05-08 |
Not clear |
| Mélodie Ferrat, Mohammad M Moein, Carmen Cananau, Tetyana Tegnebratt, Paul Saliba, Fredrik Norman, Carsten Steiger, Klas Bratteby, Erik Samén, Kenneth Dahl, Thuy A Tra. GMP production of [ EJNMMI radiopharmacy and chemistry. vol 9. issue 1. 2024-05-02. PMID:38696063. |
dopamine transporter (dat) positron emission tomography (pet) imaging has emerged as a powerful and non-invasive method to quantify dopaminergic function in the living brain. |
2024-05-02 |
2024-05-04 |
Not clear |
| Gerd P Pfeife. DNA Damage and Parkinson's Disease. International journal of molecular sciences. vol 25. issue 8. 2024-04-27. PMID:38673772. |
mitochondrial dysfunction of the respiratory chain, in combination with the presence of redox active dopamine molecules in these cells, will lead to the accumulation of reactive oxygen species (ros) in dopaminergic neurons. |
2024-04-27 |
2024-04-29 |
human |
| Hannah R Stutt, Matthew A Weber, Rachel C Cole, Alexandra S Bova, Xin Ding, Madison S McMurrin, Nandakumar S Narayana. Sex similarities and dopaminergic differences in interval timing. Behavioral neuroscience. vol 138. issue 2. 2024-04-25. PMID:38661668. |
because dopamine powerfully affects interval timing, we also examined sex differences with drugs targeting dopaminergic receptors. |
2024-04-25 |
2024-04-28 |
human |
| Kevin M Honeywell, Timothy G Freels, Megan A McWain, Abigail S Chaffin, Hunter G Nolen, Helen J Sable, Deranda B Leste. Indirect and direct cannabinoid agonists differentially affect mesolimbic dopamine release and related behaviors. Behavioral neuroscience. vol 138. issue 2. 2024-04-25. PMID:38661670. |
chronic exposure to acea decreased rearing and decreased phasic dopamine release while increasing the dopaminergic response to cocaine. |
2024-04-25 |
2024-04-28 |
mouse |
| Chiara Buoso, Markus Seifert, Martin Lang, Corey M Griffith, Begoña Talavera Andújar, Maria Paulina Castelo Rueda, Christine Fischer, Carolina Doerrier, Heribert Talasz, Alessandra Zanon, Peter P Pramstaller, Emma L Schymanski, Irene Pichler, Guenter Weis. Dopamine‑iron homeostasis interaction rescues mitochondrial fitness in Parkinson's disease. Neurobiology of disease. 2024-04-22. PMID:38648865. |
in this study, we investigated the interplay between iron, dopamine, and mitochondrial activity in neuroblastoma sh-sy5y cells and human induced pluripotent stem cell (hipsc)-derived dopaminergic neurons differentiated from a healthy control and a pd patient with a mutation in the α-synuclein (snca) gene. |
2024-04-22 |
2024-04-26 |
human |
| Chiara Buoso, Markus Seifert, Martin Lang, Corey M Griffith, Begoña Talavera Andújar, Maria Paulina Castelo Rueda, Christine Fischer, Carolina Doerrier, Heribert Talasz, Alessandra Zanon, Peter P Pramstaller, Emma L Schymanski, Irene Pichler, Guenter Weis. Dopamine‑iron homeostasis interaction rescues mitochondrial fitness in Parkinson's disease. Neurobiology of disease. 2024-04-22. PMID:38648865. |
in dopaminergic neurons derived from a healthy control individual, dopamine showed comparable effects as observed in sh-sy5y cells. |
2024-04-22 |
2024-04-26 |
human |
| Hao Yang, XiaoLi Yang, SiLu Ya. A dynamic computational model of the parallel circuit on the basal ganglia-cortex associated with Parkinson's disease dementia. Biological cybernetics. 2024-04-21. PMID:38644417. |
more importantly, the spatiotemporal course of dopamine depletion in parkinson's disease patients is well simulated, which states that with the loss of dopaminergic neurons projecting to the striatum, motor dysfunction of parkinson's disease is first observed, whereas cognitive impairment occurs after a period of onset of motor dysfunction. |
2024-04-21 |
2024-04-24 |
Not clear |
| Jose Luis Labandeira-Garcia, Carmen M Labandeira, Maria J Guerra, Ana I Rodriguez-Pere. The role of the brain renin-angiotensin system in Parkinson´s disease. Translational neurodegeneration. vol 13. issue 1. 2024-04-15. PMID:38622720. |
a decrease in the dopaminergic function induces upregulation of the angiotensin type-1 (at1) receptor activity, leading to recovery of dopamine levels. |
2024-04-15 |
2024-04-18 |
Not clear |
| Kallirhoe Kalinderi, Vasileios Papaliagkas, Liana Fidan. GLP-1 Receptor Agonists: A New Treatment in Parkinson's Disease. International journal of molecular sciences. vol 25. issue 7. 2024-04-13. PMID:38612620. |
many data on animal models and preclinical studies show that glp1-r agonists can restore dopamine levels, inhibit dopaminergic loss, attenuate neuronal degeneration and alleviate motor and non-motor features of pd. |
2024-04-13 |
2024-04-15 |
Not clear |
| Virginie Rappeneau, Fernando Castillo-Día. Convergence of Oxytocin and Dopamine Signaling in Neuronal Circuits: Insights into the Neurobiology of Social Interactions Across Species. Neuroscience and biobehavioral reviews. 2024-04-12. PMID:38608828. |
dopamine (da), is released by ventral tegmental area (vta) dopaminergic neurons, regulating social cues in the mesolimbic system. |
2024-04-12 |
2024-04-15 |
human |
| Cui Liu, Wen-Hong Liu, Wu Yang, Lei Chen, Yan Xue, Xin-Yi Che. GLP-1 modulated the firing activity of nigral dopaminergic neurons in both normal and parkinsonian mice. Neuropharmacology. 2024-04-10. PMID:38599494. |
the spontaneous firing activity of nigral dopaminergic neurons is associated with some important roles including modulation of dopamine release, expression of tyrosine hydroxylase (th), as well as neuronal survival. |
2024-04-10 |
2024-04-13 |
mouse |
| Cesar C Ceballos, Lei Ma, Maozhen Qin, Haining Zhon. Prevalent co-release of glutamate and GABA throughout the mouse brain. bioRxiv : the preprint server for biology. 2024-04-08. PMID:38585864. |
although dopaminergic axons release both glutamate and gaba in the striatum, deletion of dopamine neurons did not eliminate biphasic minis, indicating that the co-release originates from another neuronal type. |
2024-04-08 |
2024-04-10 |
mouse |
| Riccardo Avvisati, Anna-Kristin Kaufmann, Callum J Young, Gabriella E Portlock, Sophie Cancemi, Rui Ponte Costa, Peter J Magill, Paul D Dodso. Distributional coding of associative learning in discrete populations of midbrain dopamine neurons. Cell reports. vol 43. issue 4. 2024-04-06. PMID:38581677. |
here, we investigated the organizational logic of dopaminergic signaling by recording and labeling individual midbrain dopamine neurons during associative behavior. |
2024-04-06 |
2024-04-10 |
Not clear |
| Masaya Harada, Laia Serratosa Capdevila, Maria Wilhelm, Denis Burdakov, Tommaso Patriarch. Stimulation of VTA dopamine inputs to LH upregulates orexin neuronal activity in a DRD2-dependent manner. eLife. vol 12. 2024-04-03. PMID:38567902. |
it is known that hypothalamic orexinergic neurons project to dopamine neurons in the ventral tegmental area (vta), where they can stimulate dopaminergic neuronal activity. |
2024-04-03 |
2024-04-05 |
mouse |
| Masaya Harada, Laia Serratosa Capdevila, Maria Wilhelm, Denis Burdakov, Tommaso Patriarch. Stimulation of VTA dopamine inputs to LH upregulates orexin neuronal activity in a DRD2-dependent manner. eLife. vol 12. 2024-04-03. PMID:38567902. |
although there are reciprocal connections between dopaminergic and orexinergic systems, whether and how dopamine regulates the activity of orexin neurons is currently not known. |
2024-04-03 |
2024-04-05 |
mouse |
| Masaya Harada, Laia Serratosa Capdevila, Maria Wilhelm, Denis Burdakov, Tommaso Patriarch. Stimulation of VTA dopamine inputs to LH upregulates orexin neuronal activity in a DRD2-dependent manner. eLife. vol 12. 2024-04-03. PMID:38567902. |
furthermore, orexin neuron activity could also be upregulated by local stimulation of dopaminergic terminals in the lh in a way that is partially dependent on dopamine d2 receptors (drd2). |
2024-04-03 |
2024-04-05 |
mouse |
| Seong-Jin Yu, Yun Wang, Hui Shen, Eun-Kyung Bae, Yazhou Li, Kumar Sambamurti, Michael A Tones, Margaret M Zaleska, Barry J Hoffer, Nigel H Grei. DPP-4 inhibitors sitagliptin and PF-00734,200 mitigate dopaminergic neurodegeneration, neuroinflammation and behavioral impairment in the rat 6-OHDA model of Parkinson's disease. GeroScience. 2024-04-02. PMID:38563864. |
measures of dopaminergic cell viability, dopamine content, neuroinflammation and neurogenesis were evaluated thereafter in ipsi- and contralateral brain. |
2024-04-02 |
2024-04-04 |
human |
| Maya Molinari, Ori J Lieberman, David Sulzer, Emanuela Santini, Anders Borgkvis. 5-HT1B receptors mediate dopaminergic inhibition of vesicular fusion and GABA release from striatonigral synapses. bioRxiv : the preprint server for biology. 2024-04-01. PMID:38559006. |
the substantia nigra pars reticulata (snr), a crucial basal ganglia output nucleus, contains a dense expression of dopamine d1 receptors (d1rs), along with dendrites belonging to dopaminergic neurons of substantia nigra pars compacta. |
2024-04-01 |
2024-04-04 |
Not clear |
| Meghan L Bucher, Amy R Dunn, Joshua M Bradner, Kristen Stout Egerton, James P Burkett, Michelle A Johnson, Gary W Mille. Synaptic vesicle glycoprotein 2C enhances vesicular storage of dopamine and counters dopaminergic toxicity. The European journal of neuroscience. 2024-03-27. PMID:38532289. |
synaptic vesicle glycoprotein 2c enhances vesicular storage of dopamine and counters dopaminergic toxicity. |
2024-03-27 |
2024-03-29 |
mouse |