| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Natalie L Johnson, Anamaria Cotelo-Larrea, Lucas A Stetzik, Umit M Akkaya, Zihao Zhang, Marie A Gadziola, Adrienn G Varga, Minghong Ma, Daniel W Wesso. Sniffing can be initiated by dopamine's actions on ventral striatum neurons. bioRxiv : the preprint server for biology. 2024-09-04. PMID:39229099. |
here, we report that dopamine release into the ventral striatum is coupled with bouts of sniffing and that stimulation of dopaminergic terminals in these regions drives increases in respiratory rate to initiate sniffing whereas inhibition of these terminals reduces respiratory rate. |
2024-09-04 |
2024-09-06 |
Not clear |
| Marcel Schulze, David Coghill, Silke Lux, Alexandra Philipsen, Tim Sil. Assessing brain iron and its relationship to cognition and comorbidity in children with ADHD with quantitative susceptibility mapping (QSM). Biological psychiatry. Cognitive neuroscience and neuroimaging. 2024-09-01. PMID:39218036. |
brain iron and the dopaminergic system are linked since iron is an important cofactor for dopamine synthesis. |
2024-09-01 |
2024-09-04 |
Not clear |
| Carmen Duță, Corina Muscurel, Carmen Beatrice Dogaru, Irina Stoia. Ferroptosis-A Shared Mechanism for Parkinson's Disease and Type 2 Diabetes. International journal of molecular sciences. vol 25. issue 16. 2024-08-29. PMID:39201524. |
there are many similarities between the two diseases: both are chronic diseases; both are the result of a decrease in a specific substance-insulin in t2d and dopamine in pd; and both are caused by the destruction of specific cells-beta pancreatic cells in t2d and dopaminergic neurons in pd. |
2024-08-29 |
2024-09-01 |
Not clear |
| Jordan E Elum, Eric R Szelenyi, Barbara Juarez, Alexandria D Murry, Grigory Loginov, Catalina A Zamorano, Pan Gao, Ginny Wu, Scott Ng-Evans, Joshua X Yee, Xiangmin Xu, Sam A Golden, Larry S Zweife. Distinct dynamics and intrinsic properties in ventral tegmental area populations mediate reward association and motivation. Cell reports. vol 43. issue 9. 2024-08-29. PMID:39207900. |
here, we compare the contribution of two primarily dopaminergic and largely non-overlapping vta subpopulations, all vta dopamine neurons and vta gabaergic neurons of the mouse midbrain, to these processes. |
2024-08-29 |
2024-09-04 |
mouse |
| Jie Tang, Congjin Liu, Chunyi Liu, Qianyue Hu, Yi Fang, Zhengping Che. Evaluation of damage discrimination in dopaminergic neurons using dopamine transporter PET tracer [ EJNMMI research. vol 14. issue 1. 2024-08-29. PMID:39210186. |
evaluation of damage discrimination in dopaminergic neurons using dopamine transporter pet tracer [ parkinson's disease (pd) is a prevalent neurodegenerative disorder worldwide, diagnosed based on classic symptoms like motor dysfunction and cognitive impairments. |
2024-08-29 |
2024-09-04 |
Not clear |
| Yin-Hao Wang, Bo Gao, Juan Li, Long-Wei Wei, Wei Che. [Research progress on striatal D2-MSNs plasticity mediated improvement of motor dysfunction by exercises in Parkinson's disease]. Sheng li xue bao : [Acta physiologica Sinica]. vol 76. issue 4. 2024-08-28. PMID:39192794. |
parkinson's disease (pd), a prevalent neurodegenerative condition, manifests predominantly through the degeneration of nigrostriatal dopaminergic (da) pathways, culminating in a notable depletion of striatal dopamine. |
2024-08-28 |
2024-08-30 |
Not clear |
| Yanghong Zou, Tao Huang, Ailan Pang, Houjun Zhou, Xin Gen. Electroacupuncture regulates glucose metabolism by inhibiting SGLT1 levels, inhibiting microglial polarization, and alleviating Parkinson's disease. Experimental gerontology. 2024-08-28. PMID:39197673. |
the progressive degeneration and death of dopaminergic neurons leads to insufficient dopamine (da) neurotransmitters. |
2024-08-28 |
2024-09-01 |
mouse |
| b' Stephanann M Costello, Anastasia Schultz, Donald Smith, Danielle Horan, Martha Chaverra, Brian Tripet, Lynn George, Brian Bothner, Frances Lefcort, Val\\xc3\\xa9rie Copi\\xc3\\xa. Metabolic Deficits in the Retina of a Familial Dysautonomia Mouse Model. Metabolites. vol 14. issue 8. 2024-08-28. PMID:39195519.' |
as these cells have been associated with rgc loss in the neurodegenerative disease parkinson's, which shares hallmarks with fd, a targeted analysis of the dopaminergic amacrine cells and their product, dopamine, was also undertaken. |
2024-08-28 |
2024-08-30 |
mouse |
| Daisuke Hatta, Shiho Makiya, Kaito Kanamoto, Kaori Watanabe, Yuki Fuchigami, Shigeru Kawakami, Akira Kinoshita, Koh-Ichiro Yoshiura, Naohiro Kurotaki, Keiro Shirotani, Nobuhisa Iwat. Proline-rich transmembrane protein 2 regulates the magnitude and frequency of dopamine release by repetitive neuronal stimuli in the striatum of L-dopa-treated mice. Neuropsychopharmacology reports. 2024-08-28. PMID:39196683. |
thus, the enhanced and prolonged responsiveness of dopamine release in nigrostriatal dopaminergic neurons to sequential excitation may be partially implicated in prrt2-related dyskinesia. |
2024-08-28 |
2024-08-31 |
mouse |
| Massimiliano Passaretti, Roberto Cilia, Sara Rinaldo, Davide Rossi Sebastiano, Eva Orunesu, Grazia Devigili, Arianna Braccia, Giulia Paparella, Martina De Riggi, Thilo van Eimeren, Antonio Paolo Strafella, Paola Lanteri, Alfredo Berardelli, Matteo Bologna, Roberto Eleopr. Neurophysiological markers of motor compensatory mechanisms in early Parkinson's disease. Brain : a journal of neurology. 2024-08-27. PMID:39189320. |
the motor compensation coefficient includes an asymmetry score to balance motor and dopamine transporter data between the two hemispheres, in addition to a hemispheric ratio accounting for the relative mismatch between the magnitude of motor signs and dopaminergic deficit. |
2024-08-27 |
2024-08-30 |
human |
| Lydia J Hickman, Sophie L Sowden-Carvalho, Dagmar S Fraser, Bianca A Schuster, Alicia J Rybicki, Joseph M Galea, Jennifer L Coo. Dopaminergic manipulations affect the modulation and meta-modulation of movement speed: evidence from two pharmacological interventions. Behavioural brain research. 2024-08-25. PMID:39182625. |
the current paper reports effects on these kinematic features of movement following two forms of dopamine manipulation: study one highlights movement differences in individuals with pd both on and off their dopaminergic medication (n = 32); study two highlights movement differences in individuals from the general population on haloperidol (a dopamine receptor blocker, or "antagonist") and placebo (n = 43). |
2024-08-25 |
2024-08-28 |
Not clear |
| Amanda de Deus Ferreira Alves, Fernanda Carolina Ribeiro Dias, Pabyton Gonçalves Cadena, Valdemiro Amaro da Silva Junio. Use of phytocanabinoids in animal models of parkinson's disease: systematic review. Neurotoxicology. 2024-08-25. PMID:39182852. |
there was an improvement in the evaluation of dopaminergic neurons, while in relation to dopamine content, the treatment had no effect. |
2024-08-25 |
2024-08-28 |
mouse |
| Alfonso Mata-Bermudez, Ricardo Trejo-Chávez, Marina Martínez-Vargas, Adán Pérez-Arredondo, Maria de Los Ángeles Martínez-Cardenas, Araceli Diaz-Ruiz, Camilo Rios, Luz Navarr. Dysregulation of the dopaminergic system secondary to traumatic brain injury: implications for mood and anxiety disorders. Frontiers in neuroscience. vol 18. 2024-08-23. PMID:39176379. |
in this work, we summarize the studies carried out in patients who have suffered tbi and describe alterations in the dopaminergic system, highlighting (1) dysfunction of the dopaminergic neuronal circuits caused by tbi, where modifications are shown in the dopamine transporter (dat) and alterations in the expression of dopamine receptor 2 (d2r) in brain areas with dopaminergic innervation, thus establishing a hypodopaminergic state and (2) variations in the concentration of dopamine and its metabolites in biological fluids of post-tbi patients, such as elevated dopamine (da) and alterations in homovanillic acid (hva). |
2024-08-23 |
2024-08-25 |
Not clear |
| Ye-Jin Kim, Jae-Won Jung, Kyung-A Lee, Young-A Le. Impact of excessive sucrose intake on mouse behavior across different developmental stages. Neuroreport. 2024-08-22. PMID:39171853. |
amphetamine (0.5, 1, 2, and 3 mg/kg), a dopamine reuptake inhibitor, administration to assess alterations in the dopaminergic system induced increases in distance traveled after suc administration in the gtd13 and pnd21 groups compared with that in the control (vehicle administration) group. |
2024-08-22 |
2024-08-24 |
mouse |
| Yiting Ni, Qiaowen Tong, Mengying Xu, Jiayi Gu, Hua Y. Gut Microbiota-Induced Modulation of the Central Nervous System Function in Parkinson's Disease Through the Gut-Brain Axis and Short-Chain Fatty Acids. Molecular neurobiology. 2024-08-12. PMID:39134825. |
notably, fecal microbiota transplantation (fmt) from healthy to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-induced pd mouse models significantly improved motor function, enhanced dopamine and serotonin levels in the striatum, and increased the number of dopaminergic neurons in the substantia nigra while reducing glial cell activation. |
2024-08-12 |
2024-08-16 |
mouse |
| Michael V Ugrumo. Hypothalamic neurons fully or partially expressing the dopaminergic phenotype: distribution, functioning and functional significance. A review. Frontiers in neuroendocrinology. 2024-08-11. PMID:39128801. |
over time, it has been shown that besides dopaminergic neurons expressing the dopamine transporter and dopamine-synthesizing enzymes - tyrosine hydroxylase (th) and aromatic l-amino acid decarboxylase (aadc) - the hypothalamus contains neurons expressing only th, only aadc, both enzymes or only dopamine transporter. |
2024-08-11 |
2024-08-14 |
Not clear |
| Martina Di Bartolomeo, Andrea Čerňanová, Veronika Petrušová, Serena Di Martino, Július Hodosy, Filippo Drago, Vincenzo Micale, Claudio D'Addari. DNA methylation at cannabinoid type 1 and dopamine D2 receptor genes in saliva samples of psychotic subjects: is there an effect of Cannabis use? Pharmacological research. 2024-08-10. PMID:39127265. |
according to the well-documented dysregulation ofendocannabinoid and dopaminergic system genes in schizophrenia, we investigated dna methylation cannabinoid type 1 receptor (cnr1) and dopamine d2 receptor (drd2) genes in saliva samples from psychotic subjects using pyrosequencing. |
2024-08-10 |
2024-08-13 |
human |
| Jason T Magnuson, Nathan D Sy, Philip Tanabe, Chenyang Ji, Jay Gan, Daniel Schlen. Dopaminergic and anti-estrogenic responses in juvenile steelhead (Oncorhynchus mykiss) exposed to bifenthrin. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2024-08-07. PMID:39111515. |
fish brains were assessed for dopamine levels and the expression of genes involved in dopaminergic and estrogenic processes, such as catechol-o-methyltransferase (comt) and monoamine oxidase (mao). |
2024-08-07 |
2024-08-10 |
Not clear |
| Yue Li, Xianping Wang, Yufei Meng, Tuo Hu, Jun Zhao, Renjie Li, Qinru Bai, Pu Yuan, Jun Han, Kun Hao, Yiqing Wei, Yunlong Qiu, Na Li, Yan Zha. Dopamine reuptake and inhibitory mechanisms in human dopamine transporter. Nature. 2024-08-07. PMID:39112701. |
the dopamine transporter has a crucial role in regulation of dopaminergic neurotransmission by uptake of dopamine into neurons and contributes to the abuse potential of psychomotor stimulants |
2024-08-07 |
2024-08-10 |
human |
| Peng Huang, Zhiting Wan, Shaogang Q. Targeting the RUNX3-miR-186-3p-DAT-IGF1R axis as a therapeutic strategy in a Parkinson's disease model. Journal of translational medicine. vol 22. issue 1. 2024-08-06. PMID:39103832. |
furthermore, the high mir-186-3p expression in pd can be targeted to inhibit the dat expression, resulting in a decrease in the dopamine content of dopaminergic neurons. |
2024-08-06 |
2024-08-08 |
mouse |