Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
R Kuczenski, D S Segal, L D Manle. Apomorphine does not alter amphetamine-induced dopamine release measured in striatal dialysates. Journal of neurochemistry. vol 54. issue 5. 1990-05-18. PMID:2324735. |
rats were pretreated with a low dose of apomorphine (0.05 mg/kg) to inhibit dopamine neuronal activity, and the striatal dopaminergic response to amphetamine (0.5 mg/kg) was assessed by in vivo dialysis in freely moving animals. |
1990-05-18 |
2023-08-11 |
rat |
J M Cedarbau. Pharmacokinetic and pharmacodynamic considerations in management of motor response fluctuations in Parkinson's disease. Neurologic clinics. vol 8. issue 1. 1990-05-09. PMID:2181267. |
therapeutic approaches aimed at stabilizing brain dopaminergic activity include the use of slowly releasing galenic formulations of levodopa, synthetic dopamine agonists of long-lasting biologic activity, and drugs such as deprenyl that act as "dopamine extenders." |
1990-05-09 |
2023-08-11 |
Not clear |
A Chagraoui, M Vasse, P Protai. Interaction of amineptine with agents modifying dopaminergic transmission. Clinical neuropharmacology. vol 12 Suppl 2. 1990-05-08. PMID:2576526. |
these data indicate that the stimulation of dopamine receptors induced by amineptine depends to a large degree on the dopamine released from the vesicular stores by the firing rate of dopaminergic neurons. |
1990-05-08 |
2023-08-11 |
mouse |
T Nagats. [The search for endogenous or exogenous MPTP-like substances]. Rinsho shinkeigaku = Clinical neurology. vol 29. issue 12. 1990-05-04. PMID:2517047. |
like mptp, tiq inhibits tyrosine hydroxylase and nadph ubiquinone oxidoreductase to reduce dopamine and atp in the nigrostriatal dopaminergic neurons. |
1990-05-04 |
2023-08-11 |
human |
B Dean, J Kulkarni, D L Copolo. Validation of a method to measure the uptake of [3H]dopamine by human platelets. Clinica chimica acta; international journal of clinical chemistry. vol 187. issue 1. 1990-05-02. PMID:2317927. |
dopamine uptake by prp may be useful in the study of diseases with altered dopaminergic activity in the cns. |
1990-05-02 |
2023-08-11 |
human |
P J Williams, B A MacVicar, Q J Pittma. Synaptic modulation by dopamine of calcium currents in rat pars intermedia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 10. issue 3. 1990-04-30. PMID:2181078. |
this possibility was tested by examining the effects of exogenously applied dopaminergic agonists or synaptically released dopamine upon ca2+ currents recorded under single electrode voltage clamp in intact rat pars intermedia in vitro. |
1990-04-30 |
2023-08-11 |
rat |
W D Bowen, E L Moses, P J Tolentino, J M Walke. Metabolites of haloperidol display preferential activity at sigma receptors compared to dopamine D-2 receptors. European journal of pharmacology. vol 177. issue 3. 1990-04-26. PMID:2155804. |
these findings suggest that administration of haloperidol results initially in effects mediated through both dopamine and sigma receptors, but as metabolism proceeds the sigma actions would be expected to decline at a significantly slower rate than the dopaminergic actions. |
1990-04-26 |
2023-08-11 |
rat |
C Missale, C Lombardi, R De Cotiis, M Memo, M O Carruba, P F Span. Dopaminergic receptor mechanisms modulating the renin-angiotensin system and aldosterone secretion: an overview. Journal of cardiovascular pharmacology. vol 14 Suppl 8. 1990-04-25. PMID:2483440. |
dopamine, which has no significant effects on ang ii-induced aldosterone secretion in sodium-replete subjects, inhibits the hormonal response to ang ii infusion in sodium-depleted normal subjects, suggesting that the sodium balance state may be an important factor in the dopaminergic mechanisms controlling aldosterone secretion. |
1990-04-25 |
2023-08-11 |
human |
C Missale, M Metra, S Sigala, M Memo, L Dei Cas, P F Span. Inhibition of aldosterone secretion by dopamine, ibopamine, and dihydroergotoxine in patients with congestive heart failure. Journal of cardiovascular pharmacology. vol 14 Suppl 8. 1990-04-25. PMID:2483443. |
in this study we evaluated the effects of dopamine and the dopaminergic agonists ibopamine and dihydroergotoxine on aldosterone secretion and plasma renin activity in 13 patients with chronic heart failure. |
1990-04-25 |
2023-08-11 |
Not clear |
C Missale, M Metra, S Sigala, M Memo, L Dei Cas, P F Span. Inhibition of aldosterone secretion by dopamine, ibopamine, and dihydroergotoxine in patients with congestive heart failure. Journal of cardiovascular pharmacology. vol 14 Suppl 8. 1990-04-25. PMID:2483443. |
two groups of patients were noted: one responding to dopaminergic drugs with a decrease in plasma aldosterone and the other without dopamine agonist-related aldosterone suppression. |
1990-04-25 |
2023-08-11 |
Not clear |
W C Hall, R L Talbert, L Ereshefsk. Cocaine abuse and its treatment. Pharmacotherapy. vol 10. issue 1. 1990-04-24. PMID:2179901. |
dopaminergic systems are the principal sites of reward and participate in abstinence symptomatology, putatively through depletion of dopamine and changes in receptor sensitivity and responsiveness. |
1990-04-24 |
2023-08-11 |
Not clear |
A Dearry, J L Edelman, S Miller, B Burnsid. Dopamine induces light-adaptive retinomotor movements in bullfrog cones via D2 receptors and in retinal pigment epithelium via D1 receptors. Journal of neurochemistry. vol 54. issue 4. 1990-04-20. PMID:2156019. |
we previously reported that 3,4-dihydroxyphenylethylamine (dopamine) mimicked the effect of light on these movements in photo-receptors and rpe cells of green sunfish, lepomis cyanellus, by interacting with d2 dopaminergic receptors. |
1990-04-20 |
2023-08-11 |
Not clear |
A Dearry, J L Edelman, S Miller, B Burnsid. Dopamine induces light-adaptive retinomotor movements in bullfrog cones via D2 receptors and in retinal pigment epithelium via D1 receptors. Journal of neurochemistry. vol 54. issue 4. 1990-04-20. PMID:2156019. |
these results suggest that induction of cone contraction by dopamine is mediated by d2 dopaminergic receptors and that cone adenylate cyclase activity is inhibited. |
1990-04-20 |
2023-08-11 |
Not clear |
A Dearry, J L Edelman, S Miller, B Burnsid. Dopamine induces light-adaptive retinomotor movements in bullfrog cones via D2 receptors and in retinal pigment epithelium via D1 receptors. Journal of neurochemistry. vol 54. issue 4. 1990-04-20. PMID:2156019. |
these results suggest that dopamine induces pigment dispersion in bullfrog rpe via d1 dopaminergic receptors. |
1990-04-20 |
2023-08-11 |
Not clear |
M J Kuhar, P M Sanchez-Roa, D F Wong, R F Dannals, D E Grigoriadis, R Lew, M Milberge. Dopamine transporter: biochemistry, pharmacology and imaging. European neurology. vol 30 Suppl 1. 1990-04-16. PMID:2178937. |
in recent years, there has been substantial progress in studying the dopamine transporter, a unique component of the functioning dopaminergic nerve terminal. |
1990-04-16 |
2023-08-11 |
Not clear |
J Lappalainen, J Hietala, M Koulu, T Seppälä, B Sjöholm, E Syvälaht. Chronic treatment with SCH 23390 and haloperidol: effects on dopaminergic and serotonergic mechanisms in rat brain. The Journal of pharmacology and experimental therapeutics. vol 252. issue 2. 1990-04-16. PMID:2179533. |
effects of chronic administration (18 days) with sch 23390 (0.1 or 0.5 mg/kg/day s.c.) and haloperidol (1 mg/kg/day s.c.) on dopamine and serotonin synthesis and metabolism in discrete dopaminergic and serotonergic nuclei of rat brain were studied. |
1990-04-16 |
2023-08-11 |
rat |
J Lappalainen, J Hietala, M Koulu, T Seppälä, B Sjöholm, E Syvälaht. Chronic treatment with SCH 23390 and haloperidol: effects on dopaminergic and serotonergic mechanisms in rat brain. The Journal of pharmacology and experimental therapeutics. vol 252. issue 2. 1990-04-16. PMID:2179533. |
in conclusion, the classical antipsychotic drug, haloperidol, clearly decreases dopamine turnover in nigrostriatal and mesolimbic dopaminergic systems. |
1990-04-16 |
2023-08-11 |
rat |
W K Samson, L Martin, R J Mogg, R J Fulto. A nonoxytocinergic prolactin releasing factor and a nondopaminergic prolactin inhibiting factor in bovine neurointermediate lobe extracts: in vitro and in vivo studies. Endocrinology. vol 126. issue 3. 1990-04-05. PMID:2106431. |
the pif material comigrated on sizing gel chromatography with immunoreactive oxytocin and was active in vitro during dopamine blockade with domperidone and in vivo in the presence of endogenous dopaminergic tone. |
1990-04-05 |
2023-08-11 |
rat |
D Coward, K Dixon, A Enz, G Shearman, S Urwyler, T White, M Karobat. Partial brain dopamine D2 receptor agonists in the treatment of schizophrenia. Psychopharmacology bulletin. vol 25. issue 3. 1990-04-04. PMID:2576320. |
partial dopamine agonists showing high affinity but low efficacy at d2 receptors can act as dopaminergic "buffers," reducing dopaminergic activity when it is excessive, and promoting it when reduced. |
1990-04-04 |
2023-08-11 |
rat |
R E Litman, D W Hommer, T Clem, M H Rapaport, C N Pato, D Picka. Smooth pursuit eye movements in schizophrenia: effects of neuroleptic treatment and caffeine. Psychopharmacology bulletin. vol 25. issue 3. 1990-04-04. PMID:2576322. |
as caffeine has been shown to selectively increase dopaminergic neurotransmission in mesocortical neurons, further study utilizing dopamine agonists during spem in schizophrenic patients is warranted. |
1990-04-04 |
2023-08-11 |
Not clear |