| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pia Grotegut, Sandra Kuehn, Wilhelm Meißner, H Burkhard Dick, Stephanie C Joachi. Intravitreal S100B Injection Triggers a Time-Dependent Microglia Response in a Pro-Inflammatory Manner in Retina and Optic Nerve. Molecular neurobiology. vol 57. issue 2. 2020-11-25. PMID:31705442. |
intravitreal s100b injection triggers a time-dependent microglia response in a pro-inflammatory manner in retina and optic nerve. |
2020-11-25 |
2023-08-13 |
rat |
| Pia Grotegut, Sandra Kuehn, Wilhelm Meißner, H Burkhard Dick, Stephanie C Joachi. Intravitreal S100B Injection Triggers a Time-Dependent Microglia Response in a Pro-Inflammatory Manner in Retina and Optic Nerve. Molecular neurobiology. vol 57. issue 2. 2020-11-25. PMID:31705442. |
a co-localization of microglia and il-1β was noted, which correlated with an increased microglia response in retina and optic nerve at day 14. |
2020-11-25 |
2023-08-13 |
rat |
| Pia Grotegut, Sandra Kuehn, Wilhelm Meißner, H Burkhard Dick, Stephanie C Joachi. Intravitreal S100B Injection Triggers a Time-Dependent Microglia Response in a Pro-Inflammatory Manner in Retina and Optic Nerve. Molecular neurobiology. vol 57. issue 2. 2020-11-25. PMID:31705442. |
these microglia probably induce apoptotic damage in retina and optic nerve. |
2020-11-25 |
2023-08-13 |
rat |
| Elena Salobrar-García, Ana C Rodrigues-Neves, Ana I Ramírez, Rosa de Hoz, José A Fernández-Albarral, Inés López-Cuenca, José M Ramírez, António F Ambrósio, Juan J Salaza. Microglial Activation in the Retina of a Triple-Transgenic Alzheimer's Disease Mouse Model (3xTg-AD). International journal of molecular sciences. vol 21. issue 3. 2020-11-03. PMID:32012676. |
increasing evidence has shown that the retina can also be affected in ad, presenting some molecular and cellular changes in the brain, such as microglia activation. |
2020-11-03 |
2023-08-13 |
mouse |
| Elena Salobrar-García, Ana C Rodrigues-Neves, Ana I Ramírez, Rosa de Hoz, José A Fernández-Albarral, Inés López-Cuenca, José M Ramírez, António F Ambrósio, Juan J Salaza. Microglial Activation in the Retina of a Triple-Transgenic Alzheimer's Disease Mouse Model (3xTg-AD). International journal of molecular sciences. vol 21. issue 3. 2020-11-03. PMID:32012676. |
in this study, we performed, for the first time in a triple-transgenic ad mouse model (3xtg-ad), a quantitative morphometric analysis of microglia activation (using the anti-iba-1 antibody) in retinal whole-mounts, allowing visualization of the entire microglial cell, as well as its localization along the extension of the retina in different layers. |
2020-11-03 |
2023-08-13 |
mouse |
| Elena Salobrar-García, Ana C Rodrigues-Neves, Ana I Ramírez, Rosa de Hoz, José A Fernández-Albarral, Inés López-Cuenca, José M Ramírez, António F Ambrósio, Juan J Salaza. Microglial Activation in the Retina of a Triple-Transgenic Alzheimer's Disease Mouse Model (3xTg-AD). International journal of molecular sciences. vol 21. issue 3. 2020-11-03. PMID:32012676. |
compared to age-matched animals, the retina of 3xtg-ad mice presents a higher number of microglial cells and a thicker microglial cell body area. |
2020-11-03 |
2023-08-13 |
mouse |
| Elena Salobrar-García, Ana C Rodrigues-Neves, Ana I Ramírez, Rosa de Hoz, José A Fernández-Albarral, Inés López-Cuenca, José M Ramírez, António F Ambrósio, Juan J Salaza. Microglial Activation in the Retina of a Triple-Transgenic Alzheimer's Disease Mouse Model (3xTg-AD). International journal of molecular sciences. vol 21. issue 3. 2020-11-03. PMID:32012676. |
these findings demonstrate clear microglia remodeling in the retina of 3xtg-ad mice. |
2020-11-03 |
2023-08-13 |
mouse |
| Li Li, Chen Qu, Fang Wan. A novel method for co-culture with Müller cells and microglia in rat retina Biomedical reports. vol 3. issue 1. 2020-10-01. PMID:25469241. |
a novel method for co-culture with müller cells and microglia in rat retina microglia and müller cells are glial cells of the retina and constitute a functional link between neurons and vessels. |
2020-10-01 |
2023-08-13 |
rat |
| Li Li, Chen Qu, Fang Wan. A novel method for co-culture with Müller cells and microglia in rat retina Biomedical reports. vol 3. issue 1. 2020-10-01. PMID:25469241. |
the aim of the present study was to introduce a novel method of co-culture with müller cells and microglia in rat retina. |
2020-10-01 |
2023-08-13 |
rat |
| Li Li, Chen Qu, Fang Wan. A novel method for co-culture with Müller cells and microglia in rat retina Biomedical reports. vol 3. issue 1. 2020-10-01. PMID:25469241. |
co-culture with müller cells and microglia in the retina is economical and useful for future methods in microglia and müller cell research. |
2020-10-01 |
2023-08-13 |
rat |
| Mücella Arikan Yorgun, Khalid Rashid, Alexander Aslanidis, Charlotte Bresgen, Katharina Dannhausen, Thomas Langman. Crocin, a plant-derived carotenoid, modulates microglial reactivity. Biochemistry and biophysics reports. vol 12. 2020-10-01. PMID:29214225. |
microglia activation plays an important role in immune responses in the cns including the retina. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yubin Huang, Zhen Xu, Shanshan Xiong, Guangrong Qin, Fangfang Sun, Jian Yang, Ti-Fei Yuan, Lei Zhao, Ke Wang, Yu-Xiang Liang, Lin Fu, Tianzhun Wu, Kwok-Fai So, Yanxia Rao, Bo Pen. Dual extra-retinal origins of microglia in the model of retinal microglia repopulation. Cell discovery. vol 4. 2020-10-01. PMID:29507754. |
microglia have also shown the capacity to repopulate the retina after eliminating all retinal microglia. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yubin Huang, Zhen Xu, Shanshan Xiong, Guangrong Qin, Fangfang Sun, Jian Yang, Ti-Fei Yuan, Lei Zhao, Ke Wang, Yu-Xiang Liang, Lin Fu, Tianzhun Wu, Kwok-Fai So, Yanxia Rao, Bo Pen. Dual extra-retinal origins of microglia in the model of retinal microglia repopulation. Cell discovery. vol 4. 2020-10-01. PMID:29507754. |
in this study, we aim to investigate the origins of repopulated microglia in the retina. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yubin Huang, Zhen Xu, Shanshan Xiong, Guangrong Qin, Fangfang Sun, Jian Yang, Ti-Fei Yuan, Lei Zhao, Ke Wang, Yu-Xiang Liang, Lin Fu, Tianzhun Wu, Kwok-Fai So, Yanxia Rao, Bo Pen. Dual extra-retinal origins of microglia in the model of retinal microglia repopulation. Cell discovery. vol 4. 2020-10-01. PMID:29507754. |
therefore, we have for the first time identified the extra-retinal origins of microglia in the adult mammalian retina by using a model of microglial repopulation, which may shed light on the target exploration of therapeutic interventions for retinal degenerative disorders. |
2020-10-01 |
2023-08-13 |
Not clear |
| David J Valent, Wai T Wong, Emily Y Chew, Catherine A Cukra. Oral Dextromethorphan for the Treatment of Diabetic Macular Edema: Results From a Phase I/II Clinical Study. Translational vision science & technology. vol 7. issue 6. 2020-10-01. PMID:30584490. |
the activation of microglia, the primary innate immune cell resident in the retina, produces inflammatory mediators, which underlie changes in diabetic retinopathy including increased vascular permeability. |
2020-10-01 |
2023-08-13 |
Not clear |
| Zhuolin Liu, Johnny Tam, Osamah Saeedi, Daniel X Hamme. Trans-retinal cellular imaging with multimodal adaptive optics. Biomedical optics express. vol 9. issue 9. 2020-10-01. PMID:30615699. |
the mao system imaging performance was demonstrated by visualization of cells in their mosaic arrangement across the full depth of the retina in three human subjects, including microglia, nerve fiber bundles, retinal ganglion cells and axons, and capillaries in the inner retina and foveal cones, peripheral rods, and retinal pigment epithelial cells in the outer retina. |
2020-10-01 |
2023-08-13 |
human |
| Agustina Noailles, Oksana Kutsyr, Victoria Maneu, Isabel Ortuño-Lizarán, Laura Campello, Emilio de Juan, Violeta Gómez-Vicente, Nicolás Cuenca, Pedro La. The Absence of Toll-Like Receptor 4 Mildly Affects the Structure and Function in the Adult Mouse Retina. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:30873007. |
these results suggest that tlr4 deletion causes functional alterations in terms of visual response and acuity, probably through the loss of bipolar cells and microglia, but this receptor is not essential for the processing of visual information in the retina. |
2020-10-01 |
2023-08-13 |
mouse |
| Nan Su, Sigrid März, Tanja Plagemann, Jiahui Cao, Hans-Joachim Schnittler, Nicole Eter, Peter Heiduschk. Occurrence of Transmembrane Protein 119 in the Retina is Not Restricted to the Microglia: An Immunohistochemical Study. Translational vision science & technology. vol 8. issue 6. 2020-10-01. PMID:31853425. |
occurrence of transmembrane protein 119 in the retina is not restricted to the microglia: an immunohistochemical study. |
2020-10-01 |
2023-08-13 |
Not clear |
| Diana M Mitchell, Chi Sun, Samuel S Hunter, Daniel D New, Deborah L Stenkam. Regeneration associated transcriptional signature of retinal microglia and macrophages. Scientific reports. vol 9. issue 1. 2020-09-30. PMID:30886241. |
however, the roles of another important class of glia present in the retina, microglia, during this regenerative phase remain elusive. |
2020-09-30 |
2023-08-13 |
zebrafish |
| Juncai He, Congjian Zhao, Jiaman Dai, Chuan Huang Weng, Bai Shi Jiao Bian, Yu Gong, Lingling Ge, Yajie Fang, Hui Liu, Haiwei Xu, Zheng Qin Yi. Microglia Mediate Synaptic Material Clearance at the Early Stage of Rats With Retinitis Pigmentosa. Frontiers in immunology. vol 10. 2020-09-30. PMID:31105708. |
resident microglia are the main immune cells in the retina and play a key role in the pathogenesis of retinitis pigmentosa (rp). |
2020-09-30 |
2023-08-13 |
rat |