| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Scott W McPherson, Neal D Heuss, Ute Lehmann, Heidi Roehrich, Md Abedin, Dale S Gregerso. The retinal environment induces microglia-like properties in recruited myeloid cells. Journal of neuroinflammation. vol 16. issue 1. 2020-01-13. PMID:31325968. |
here, we ask whether new myeloid cells recruited to the retina are constrained to resemble endogenous microglia morphologically and functionally. |
2020-01-13 |
2023-08-13 |
Not clear |
| Federica Maria Conedera, Ana Maria Quintela Pousa, Nadia Mercader, Markus Tschopp, Volker Enzman. Retinal microglia signaling affects Müller cell behavior in the zebrafish following laser injury induction. Glia. vol 67. issue 6. 2019-12-30. PMID:30794326. |
microglia are the resident tissue macrophages of the central nervous system including the retina. |
2019-12-30 |
2023-08-13 |
zebrafish |
| Federica Maria Conedera, Ana Maria Quintela Pousa, Nadia Mercader, Markus Tschopp, Volker Enzman. Retinal microglia signaling affects Müller cell behavior in the zebrafish following laser injury induction. Glia. vol 67. issue 6. 2019-12-30. PMID:30794326. |
under pathophysiological conditions, microglia can signal to müller cells, the major glial component of the retina, affecting their morphological, molecular, and functional responses. |
2019-12-30 |
2023-08-13 |
zebrafish |
| Federica Maria Conedera, Ana Maria Quintela Pousa, Nadia Mercader, Markus Tschopp, Volker Enzman. Retinal microglia signaling affects Müller cell behavior in the zebrafish following laser injury induction. Glia. vol 67. issue 6. 2019-12-30. PMID:30794326. |
thus, microglia and müller cell signaling is pivotal to unlock the regenerative potential of müller cells in order to repair the damaged retina. |
2019-12-30 |
2023-08-13 |
zebrafish |
| Anna Polosa, Shasha Lv, Wassila Ait Igrine, Laura-Alexie Chevrolat, Hyba Bessaklia, Pierre Lachapell. Evidences Suggesting that Distinct Immunological and Cellular Responses to Light Damage Distinguishes Juvenile and Adult Rat Retinas. International journal of molecular sciences. vol 20. issue 11. 2019-11-25. PMID:31167447. |
ihc revealed a subtle migration of microglia (iba1 marker) from the inner to the outer retina after 3 days of exposure in jr contrasting with the stronger reaction seen after 1 day in ar. |
2019-11-25 |
2023-08-13 |
rat |
| Eleftherios I Paschalis, Fengyang Lei, Chengxin Zhou, Xiaohong Nancy Chen, Vassiliki Kapoulea, Pui-Chuen Hui, Reza Dana, James Chodosh, Demetrios G Vavvas, Claes H Dohlma. Microglia Regulate Neuroglia Remodeling in Various Ocular and Retinal Injuries. Journal of immunology (Baltimore, Md. : 1950). vol 202. issue 2. 2019-10-28. PMID:30541880. |
reactive microglia and infiltrating peripheral monocytes have been implicated in many neurodegenerative diseases of the retina and cns. |
2019-10-28 |
2023-08-13 |
mouse |
| Yikui Zhang, Lian Zhao, Xu Wang, Wenxin Ma, Adam Lazere, Hao-Hua Qian, Jun Zhang, Mones Abu-Asab, Robert N Fariss, Jerome E Roger, Wai T Won. Repopulating retinal microglia restore endogenous organization and function under CX3CL1-CX3CR1 regulation. Science advances. vol 4. issue 3. 2019-09-05. PMID:29750189. |
we examined microglial homeostasis in the adult mouse retina, a specialized neural compartment containing regular arrays of microglia in discrete synaptic laminae that can be directly visualized. |
2019-09-05 |
2023-08-13 |
mouse |
| Yikui Zhang, Lian Zhao, Xu Wang, Wenxin Ma, Adam Lazere, Hao-Hua Qian, Jun Zhang, Mones Abu-Asab, Robert N Fariss, Jerome E Roger, Wai T Won. Repopulating retinal microglia restore endogenous organization and function under CX3CL1-CX3CR1 regulation. Science advances. vol 4. issue 3. 2019-09-05. PMID:29750189. |
using in vivo imaging and cell-fate mapping techniques, we discovered that repopulation originated from residual microglia proliferating in the central inner retina that subsequently spread by centrifugal migration to fully recapitulate pre-existing microglial distributions and morphologies. |
2019-09-05 |
2023-08-13 |
mouse |
| Emily G O'Koren, Chen Yu, Mikael Klingeborn, Alicia Y W Wong, Cameron L Prigge, Rose Mathew, Joan Kalnitsky, Rasha A Msallam, Aymeric Silvin, Jeremy N Kay, Catherine Bowes Rickman, Vadim Y Arshavsky, Florent Ginhoux, Miriam Merad, Daniel R Saba. Microglial Function Is Distinct in Different Anatomical Locations during Retinal Homeostasis and Degeneration. Immunity. vol 50. issue 3. 2019-08-20. PMID:30850344. |
we combined lineage tracing, single-cell transcriptomics, and electrophysiology of the mouse retina and showed that adult retinal microglia shared a common developmental lineage and were long-lived but resided in two distinct niches. |
2019-08-20 |
2023-08-13 |
mouse |
| Jonathan B Lin, Rajendra S Apt. Visualizing the Heterogeneity of Retinal Microglia. Immunity. vol 50. issue 3. 2019-08-15. PMID:30893583. |
(2019) report that murine retinal microglia are long lived and are divided into two spatially and functionally distinct niches in the retina. |
2019-08-15 |
2023-08-13 |
Not clear |
| Lijuan Zhang, Xuan Cui, Ruben Jauregui, Karen Sophia Park, Sally Justus, Yi-Ting Tsai, Jimmy K Duong, Chun-Wei Hsu, Wen-Hsuan Wu, Christine L Xu, Chyuan-Sheng Lin, Stephen H Tsan. Genetic Rescue Reverses Microglial Activation in Preclinical Models of Retinitis Pigmentosa. Molecular therapy : the journal of the American Society of Gene Therapy. vol 26. issue 8. 2019-07-29. PMID:30001913. |
microglia cells (mgcs) play a key role in scavenging pathogens and phagocytosing cellular debris in the central nervous system and retina. |
2019-07-29 |
2023-08-13 |
mouse |
| Daniel R Saba. New concepts in macrophage ontogeny in the adult neural retina. Cellular immunology. vol 330. 2019-06-24. PMID:29703455. |
yet, little attention has been payed to the retina as compared to elsewhere in the central nervous system with respect to microglia, the macrophages of the neural parenchyma. |
2019-06-24 |
2023-08-13 |
human |
| Daniel R Saba. New concepts in macrophage ontogeny in the adult neural retina. Cellular immunology. vol 330. 2019-06-24. PMID:29703455. |
the current review covers topical concepts on adult microglia and perivascular macrophage ontogenies in the steady state retina, as well as parallels made with these macrophages in other areas of the central nervous system. |
2019-06-24 |
2023-08-13 |
human |
| Wenqin Xu, Zhicha Hu, Yang Lv, Guorui Dou, Zifeng Zhang, Haiyan Wang, Yusheng Wan. Microglial density determines the appearance of pathological neovascular tufts in oxygen-induced retinopathy. Cell and tissue research. vol 374. issue 1. 2019-06-17. PMID:29767277. |
therefore, these data suggest that the density of microglia in the retina may determine the result of vasculopathy in oir mice to some extent. |
2019-06-17 |
2023-08-13 |
mouse |
| Sean M Silverman, Wai T Won. Microglia in the Retina: Roles in Development, Maturity, and Disease. Annual review of vision science. vol 4. 2019-06-14. PMID:29852094. |
microglia in the retina: roles in development, maturity, and disease. |
2019-06-14 |
2023-08-13 |
Not clear |
| Sean M Silverman, Wai T Won. Microglia in the Retina: Roles in Development, Maturity, and Disease. Annual review of vision science. vol 4. 2019-06-14. PMID:29852094. |
microglia, the primary resident immune cell type, constitute a key population of glia in the retina. |
2019-06-14 |
2023-08-13 |
Not clear |
| Sean M Silverman, Wai T Won. Microglia in the Retina: Roles in Development, Maturity, and Disease. Annual review of vision science. vol 4. 2019-06-14. PMID:29852094. |
recent evidence indicates that microglia play significant functional roles in the retina at different life stages. |
2019-06-14 |
2023-08-13 |
Not clear |
| Sean M Silverman, Wai T Won. Microglia in the Retina: Roles in Development, Maturity, and Disease. Annual review of vision science. vol 4. 2019-06-14. PMID:29852094. |
during adulthood, ramified microglia in the plexiform layers interact closely with synapses to maintain synaptic structure and function that underlie the retina's electrophysiological response to light. |
2019-06-14 |
2023-08-13 |
Not clear |
| Hideto Koso, Ryuichi Nishinakamura, Sumiko Watanab. Sall1 Regulates Microglial Morphology Cell Autonomously in the Developing Retina. Advances in experimental medicine and biology. vol 1074. 2019-05-06. PMID:29721946. |
retinal degeneration often accompanies microglial activation and infiltration of monocyte-derived macrophages into the retina, resulting in the coexistence of microglia and monocyte-derived macrophages in the retina. |
2019-05-06 |
2023-08-13 |
mouse |
| Hideto Koso, Ryuichi Nishinakamura, Sumiko Watanab. Sall1 Regulates Microglial Morphology Cell Autonomously in the Developing Retina. Advances in experimental medicine and biology. vol 1074. 2019-05-06. PMID:29721946. |
we previously showed that the sall1 zinc-finger transcriptional factor is expressed specifically in microglia within the retinal phagocyte pool, and analyses of sall1 knockout mice revealed that microglial morphology changed from a ramified to a more amoeboid appearance in the developing retina. |
2019-05-06 |
2023-08-13 |
mouse |