| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yoko Okunuki, Ryo Mukai, Takeshi Nakao, Steven J Tabor, Oleg Butovsky, Reza Dana, Bruce R Ksander, Kip M Conno. Retinal microglia initiate neuroinflammation in ocular autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 20. 2020-03-30. PMID:31023885. |
in the absence of microglia, uveitis does not develop, since leukocytes cannot gain entry through the blood-retinal barrier, illustrating that microglia play a critical role in regulating infiltration of inflammatory cells into the retina. |
2020-03-30 |
2023-08-13 |
Not clear |
| Sean K Wang, Yunlu Xue, Parimal Rana, Christin M Hong, Constance L Cepk. Soluble CX3CL1 gene therapy improves cone survival and function in mouse models of retinitis pigmentosa. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 20. 2020-03-30. PMID:31036641. |
aav8-scx3cl1 did not affect rod survival, microglia localization, or inflammatory cytokine levels in the retina. |
2020-03-30 |
2023-08-13 |
mouse |
| Eric B Miller, Pengfei Zhang, Karli Ching, Edward N Pugh, Marie E Burn. In vivo imaging reveals transient microglia recruitment and functional recovery of photoreceptor signaling after injury. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 33. 2020-03-25. PMID:31350349. |
here, we have used in vivo high-resolution optical coherence tomography (oct) and scanning laser ophthalmoscopy with and without adaptive optics to quantify the 3d distribution and dynamics of microglia in the living retina before and after local damage to photoreceptors. |
2020-03-25 |
2023-08-13 |
Not clear |
| Eric B Miller, Pengfei Zhang, Karli Ching, Edward N Pugh, Marie E Burn. In vivo imaging reveals transient microglia recruitment and functional recovery of photoreceptor signaling after injury. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 33. 2020-03-25. PMID:31350349. |
following photoreceptor injury, microglia migrated both laterally and vertically through the retina over many hours, forming a tight cluster within the area of visible damage that resolved over 2 wk. |
2020-03-25 |
2023-08-13 |
Not clear |
| Sarah R Anderson, Jianmin Zhang, Michael R Steele, Cesar O Romero, Amanda G Kautzman, Dorothy P Schafer, Monica L Vette. Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by Microglia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 11. 2020-03-16. PMID:30647151. |
here, we investigate microglia function during embryonic mouse retina development, where only microglia, progenitors, and neurons are present. |
2020-03-16 |
2023-08-13 |
mouse |
| Rayne R Lim, Dean P Hainsworth, Rajiv R Mohan, Shyam S Chaurasi. Characterization of a functionally active primary microglial cell culture from the pig retina. Experimental eye research. vol 185. 2020-02-28. PMID:31103710. |
characterization of a functionally active primary microglial cell culture from the pig retina. |
2020-02-28 |
2023-08-13 |
human |
| Samuel M Peterson, Trevor J McGill, Teresa Puthussery, Jonathan Stoddard, Lauren Renner, Anne D Lewis, Lois M A Colgin, Jacqueline Gayet, Xiaojie Wang, Kamm Prongay, Cassandra Cullin, Brandy L Dozier, Betsy Ferguson, Martha Neuringe. Bardet-Biedl Syndrome in rhesus macaques: A nonhuman primate model of retinitis pigmentosa. Experimental eye research. vol 189. 2020-02-28. PMID:31589838. |
histological assessments in the 4- and 6-year-old cases confirmed profound loss of photoreceptors and inner retinal neurons across the posterior retina, with dramatic thinning and disorganization of all cell layers, abundant microglia, absent or displaced rpe cells, and significant gliosis in the subretinal space. |
2020-02-28 |
2023-08-13 |
human |
| A Tisi, M Passacantando, M Ciancaglini, R Maccaron. Nanoceria neuroprotective effects in the light-damaged retina: A focus on retinal function and microglia activation. Experimental eye research. vol 188. 2020-02-21. PMID:31520599. |
nanoceria neuroprotective effects in the light-damaged retina: a focus on retinal function and microglia activation. |
2020-02-21 |
2023-08-13 |
human |
| A Tisi, M Passacantando, M Ciancaglini, R Maccaron. Nanoceria neuroprotective effects in the light-damaged retina: A focus on retinal function and microglia activation. Experimental eye research. vol 188. 2020-02-21. PMID:31520599. |
the light damage model is characterised by oxidative stress upregulation followed by photoreceptor death and microglia activation in the outer retina. |
2020-02-21 |
2023-08-13 |
human |
| A Tisi, M Passacantando, M Ciancaglini, R Maccaron. Nanoceria neuroprotective effects in the light-damaged retina: A focus on retinal function and microglia activation. Experimental eye research. vol 188. 2020-02-21. PMID:31520599. |
the electrical responses of the retina and the microglia number and morphology are clearly modulated by the treatment, supporting the beneficial effects of cerium oxide nanoparticles to counteract the degeneration processes in the retina. |
2020-02-21 |
2023-08-13 |
human |
| Gurugirijha Rathnasamy, Wallace S Foulds, Eng-Ang Ling, Charanjit Kau. Retinal microglia - A key player in healthy and diseased retina. Progress in neurobiology. vol 173. 2020-02-17. PMID:29864456. |
retinal microglia - a key player in healthy and diseased retina. |
2020-02-17 |
2023-08-13 |
Not clear |
| Gurugirijha Rathnasamy, Wallace S Foulds, Eng-Ang Ling, Charanjit Kau. Retinal microglia - A key player in healthy and diseased retina. Progress in neurobiology. vol 173. 2020-02-17. PMID:29864456. |
microglia, the resident immune cells of the brain and retina, are constantly engaged in the surveillance of their surrounding neural tissue. |
2020-02-17 |
2023-08-13 |
Not clear |
| Gurugirijha Rathnasamy, Wallace S Foulds, Eng-Ang Ling, Charanjit Kau. Retinal microglia - A key player in healthy and diseased retina. Progress in neurobiology. vol 173. 2020-02-17. PMID:29864456. |
the contribution of microglia in maintaining the purposeful and functional histo-architecture of the adult retina is indispensable. |
2020-02-17 |
2023-08-13 |
Not clear |
| Gurugirijha Rathnasamy, Wallace S Foulds, Eng-Ang Ling, Charanjit Kau. Retinal microglia - A key player in healthy and diseased retina. Progress in neurobiology. vol 173. 2020-02-17. PMID:29864456. |
in light of the above, the focus of this review is to highlight the role played by microglia in the healthy and diseased retina, based on findings of our own work and from that of others. |
2020-02-17 |
2023-08-13 |
Not clear |
| Paul G McMenamin, Daniel R Saban, Samantha J Dand. Immune cells in the retina and choroid: Two different tissue environments that require different defenses and surveillance. Progress in retinal and eye research. vol 70. 2020-02-07. PMID:30552975. |
this is in marked contrast to the neural parenchyma of the retina, which is populated almost solely by microglia. |
2020-02-07 |
2023-08-13 |
Not clear |
| Isha Akhtar-Schaefer, Raphael Reuten, Manuel Koch, Markus Pietsch, Thomas Langman. AMD-Associated HTRA1 Variants Do Not Influence TGF-β Signaling in Microglia. Advances in experimental medicine and biology. vol 1185. 2020-02-05. PMID:31884580. |
htra1 is known to inhibit transforming growth factor-β (tgf-β) signaling, a pathway regulating quiescence of microglia, the resident immune cells of the brain and retina. |
2020-02-05 |
2023-08-13 |
Not clear |
| C Henrique Alves, Jan Wijnhold. Microglial Cell Dysfunction in CRB1-Associated Retinopathies. Advances in experimental medicine and biology. vol 1185. 2020-02-05. PMID:31884605. |
microglia are the resident immune surveyor cells in the retina, and their roles have been heavily studied in several retinal diseases, including retinitis pigmentosa (rp), age-related macular degeneration, and diabetic retinopathy. |
2020-02-05 |
2023-08-13 |
Not clear |
| Chen Yu, Daniel R Saba. Identification of a Unique Subretinal Microglia Type in Retinal Degeneration Using Single Cell RNA-Seq. Advances in experimental medicine and biology. vol 1185. 2020-02-05. PMID:31884609. |
as the resident macrophages of central nervous system, microglia reside in the plexiform and nerve fiber layers of the retina. |
2020-02-05 |
2023-08-13 |
mouse |
| Jose A Fernández-Albarral, Ana I Ramírez, Rosa de Hoz, Nerea López-Villarín, Elena Salobrar-García, Inés López-Cuenca, Ester Licastro, Antonio M Inarejos-García, Paula Almodóvar, Maria D Pinazo-Durán, José M Ramírez, Juan J Salaza. Neuroprotective and Anti-Inflammatory Effects of a Hydrophilic Saffron Extract in a Model of Glaucoma. International journal of molecular sciences. vol 20. issue 17. 2020-01-22. PMID:31443568. |
activation of immune cells resident in the retina (microglia) may contribute to rgc death. |
2020-01-22 |
2023-08-13 |
mouse |
| Levi Todd, Isabella Palazzo, Lilianna Suarez, Xiaoyu Liu, Leo Volkov, Thanh V Hoang, Warren A Campbell, Seth Blackshaw, Ning Quan, Andy J Fische. Reactive microglia and IL1β/IL-1R1-signaling mediate neuroprotection in excitotoxin-damaged mouse retina. Journal of neuroinflammation. vol 16. issue 1. 2020-01-13. PMID:31170999. |
reactive microglia and il1β/il-1r1-signaling mediate neuroprotection in excitotoxin-damaged mouse retina. |
2020-01-13 |
2023-08-13 |
mouse |