| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mu Sun, Jonathan C Gewirtz, Lisa Bofenkamp, Robert J Wickham, Hong Ge, Michael B O'Conno. Canonical TGF-beta signaling is required for the balance of excitatory/inhibitory transmission within the hippocampus and prepulse inhibition of acoustic startle. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 17. 2010-05-24. PMID:20427661. |
however, these mutant mice did show enhancement of paired-pulse facilitation in excitatory synaptic transmission and stronger paired-pulse depression of gaba(a) currents in the hippocampus. |
2010-05-24 |
2023-08-12 |
mouse |
| Gerard Sanacor. Cortical inhibition, gamma-aminobutyric acid, and major depression: there is plenty of smoke but is there fire? Biological psychiatry. vol 67. issue 5. 2010-05-20. PMID:20159143. |
cortical inhibition, gamma-aminobutyric acid, and major depression: there is plenty of smoke but is there fire? |
2010-05-20 |
2023-08-12 |
Not clear |
| Antonio Alcaro, Jaak Panksepp, Jan Witczak, Dave J Hayes, Georg Northof. Is subcortical-cortical midline activity in depression mediated by glutamate and GABA? A cross-species translational approach. Neuroscience and biobehavioral reviews. vol 34. issue 4. 2010-05-07. PMID:19958790. |
is subcortical-cortical midline activity in depression mediated by glutamate and gaba? |
2010-05-07 |
2023-08-12 |
human |
| Antonio Alcaro, Jaak Panksepp, Jan Witczak, Dave J Hayes, Georg Northof. Is subcortical-cortical midline activity in depression mediated by glutamate and GABA? A cross-species translational approach. Neuroscience and biobehavioral reviews. vol 34. issue 4. 2010-05-07. PMID:19958790. |
this cross-species translational investigation suggests that resting state hyperactivity in depression occurs in subcortical and cortical midline regions and is mediated by glutamate and gaba metabolism. |
2010-05-07 |
2023-08-12 |
human |
| Jimok Kim, Bradley E Alge. Reduction in endocannabinoid tone is a homeostatic mechanism for specific inhibitory synapses. Nature neuroscience. vol 13. issue 5. 2010-05-07. PMID:20348918. |
the consequent reduction in basal stimulation of cannabinoid receptors augmented gaba release probability, fostering rapid depression of synaptic inhibition and on-demand disinhibition. |
2010-05-07 |
2023-08-12 |
rat |
| Kelly J Skilbeck, Graham A R Johnston, Tina Hinto. Stress and GABA receptors. Journal of neurochemistry. vol 112. issue 5. 2010-03-15. PMID:20002524. |
the short- and long-term stress sensitivity of the gabaergic system implicates gaba(a) receptors in the non-genetic etiology of psychiatric illnesses such as depression and schizophrenia in which stress may be an important factor. |
2010-03-15 |
2023-08-12 |
Not clear |
| S Grassi, A Frondaroli, M Scarduzio, M B Dutia, C Dieni, V E Pettoross. Effects of 17beta-estradiol on glutamate synaptic transmission and neuronal excitability in the rat medial vestibular nuclei. Neuroscience. vol 165. issue 4. 2010-03-12. PMID:19944747. |
in contrast, the depression of the spontaneous discharge of type a and type b neurons appears to depend on e(2) modulation of intrinsic ion conductances, as the effect remains after blockade of glutamate, gaba and glycine receptors (glyrs). |
2010-03-12 |
2023-08-12 |
rat |
| Maddalena D Caiati, Sudhir Sivakumaran, Enrico Cherubin. In the developing rat hippocampus, endogenous activation of presynaptic kainate receptors reduces GABA release from mossy fiber terminals. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 5. 2010-03-05. PMID:20130184. |
the gluk1-induced depression of mf-gpscs would prevent excessive activation of the ca3 associative network by the excitatory action of gaba and the emergence of seizures in the immature brain. |
2010-03-05 |
2023-08-12 |
rat |
| Marco Rohde, Tursonjan Tokay, Rüdiger Köhling, Timo Kirschstei. GABA(A) receptor inhibition does not affect mGluR-dependent LTD at hippocampal Schaffer collateral-CA1 synapses. Neuroscience letters. vol 467. issue 1. 2010-02-25. PMID:19800390. |
without gaba(a)r blockade, mglur-dependent ltd was induced pharmacologically by the group i mglur agonist (rs)-3,5-dihydroxyphenylglycine (dhpg, 100 microm, 10 min) as well as electrically by paired-pulse low-frequency stimulation (pp-lfs, 900 paired pulses at 1hz) resulting in a stable depression of the field response lasting at least 80 min after ltd induction. |
2010-02-25 |
2023-08-12 |
rat |
| Irina Esterlis, Kelly P Cosgrove, Jeffery C Batis, Frederic Bois, Tracy A Kloczynski, Stephanie M Stiklus, Edward Perry, Gilles D Tamagnan, John P Seibyl, Robert Makuch, Suchitra Krishnan-Sarin, Stephanie O'Malley, Julie K Stale. GABAA-benzodiazepine receptor availability in smokers and nonsmokers: relationship to subsyndromal anxiety and depression. Synapse (New York, N.Y.). vol 63. issue 12. 2010-02-17. PMID:19642218. |
the relationship between cortical gaba(a)-bzr availability, smoking status, and subsyndromal depression and anxiety symptoms, as well as pain tolerance and sensitivity, were evaluated. |
2010-02-17 |
2023-08-12 |
Not clear |
| Irina Esterlis, Kelly P Cosgrove, Jeffery C Batis, Frederic Bois, Tracy A Kloczynski, Stephanie M Stiklus, Edward Perry, Gilles D Tamagnan, John P Seibyl, Robert Makuch, Suchitra Krishnan-Sarin, Stephanie O'Malley, Julie K Stale. GABAA-benzodiazepine receptor availability in smokers and nonsmokers: relationship to subsyndromal anxiety and depression. Synapse (New York, N.Y.). vol 63. issue 12. 2010-02-17. PMID:19642218. |
aberrant regulation of gaba(a)-bzr function in vulnerable smokers may explain why some smokers experience subsyndromal anxiety and depression. |
2010-02-17 |
2023-08-12 |
Not clear |
| Xuan Pham, Cuie Sun, Xiangning Chen, Edwin J C G van den Oord, Michael C Neale, Kenneth S Kendler, John M Hettem. Association study between GABA receptor genes and anxiety spectrum disorders. Depression and anxiety. vol 26. issue 11. 2010-02-01. PMID:19842164. |
in this investigation, we explored four gaba receptor genes for their possible associations with genetic risk for anxiety disorders and depression. |
2010-02-01 |
2023-08-12 |
human |
| Takanori Tsujimura, Masahiro Kondo, Junichi Kitagawa, Yoshiyuki Tsuboi, Kimiko Saito, Haruka Tohara, Koichiro Ueda, Barry J Sessle, Koichi Iwat. Involvement of ERK phosphorylation in brainstem neurons in modulation of swallowing reflex in rats. The Journal of physiology. vol 587. issue Pt 4. 2009-12-07. PMID:19124539. |
the local microinjection of the gaba(a) receptor agonist muscimol into the nts produced a significant reduction in swallowing reflex, and the capsaicin-induced depression of the swallowing reflex was abolished by microinjection of the gaba(a) receptor antagonist bicuculline into the nts. |
2009-12-07 |
2023-08-12 |
rat |
| Simone Astori, Rafael Luján, Georg Köh. GABA release from cerebellar stellate cells is developmentally regulated by presynaptic GABA(B) receptors in a target-cell-specific manner. The European journal of neuroscience. vol 30. issue 4. 2009-11-17. PMID:19674089. |
similarly, modulation of gaba release by presynaptic gaba(b) receptors changed during development in purkinje cells but not in stellate cells, as demonstrated by the baclofen-mediated depression of mipsc frequency and evoked ipsc (eipsc) amplitudes. |
2009-11-17 |
2023-08-12 |
mouse |
| M Bruce MacIve. Abused inhalants enhance GABA-mediated synaptic inhibition. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 10. 2009-10-29. PMID:19494804. |
this depression appeared to involve enhanced gaba-mediated inhibition, evident in its reversal by a gaba receptor antagonist. |
2009-10-29 |
2023-08-12 |
rat |
| M Zink, B Vollmayr, P J Gebicke-Haerter, F A Hen. Reduced expression of GABA transporter GAT3 in helpless rats, an animal model of depression. Neurochemical research. vol 34. issue 9. 2009-10-19. PMID:19288275. |
reduced expression of gaba transporter gat3 in helpless rats, an animal model of depression. |
2009-10-19 |
2023-08-12 |
rat |
| M Zink, B Vollmayr, P J Gebicke-Haerter, F A Hen. Reduced expression of GABA transporter GAT3 in helpless rats, an animal model of depression. Neurochemical research. vol 34. issue 9. 2009-10-19. PMID:19288275. |
reduced gaba transporter expression is well in concert with the behavioural phenotypes of knockout animals and strengthens the hypothesis of impaired glial functions in depression. |
2009-10-19 |
2023-08-12 |
rat |
| Pan-Yue Deng, Zhaoyang Xiao, Chuanxiu Yang, Lalida Rojanathammanee, Laurel Grisanti, John Watt, Jonathan D Geiger, Rugao Liu, James E Porter, Saobo Le. GABA(B) receptor activation inhibits neuronal excitability and spatial learning in the entorhinal cortex by activating TREK-2 K+ channels. Neuron. vol 63. issue 2. 2009-09-30. PMID:19640481. |
depression of neuronal excitability in the ec underlies gaba(b) receptor-mediated inhibition of spatial learning as assessed by morris water maze. |
2009-09-30 |
2023-08-12 |
Not clear |
| Esra Küçükibrahimoğlu, Melek Z Saygin, Mecit Calişkan, Okan K Kaplan, Cüneyt Unsal, M Zafer Göre. The change in plasma GABA, glutamine and glutamate levels in fluoxetine- or S-citalopram-treated female patients with major depression. European journal of clinical pharmacology. vol 65. issue 6. 2009-08-18. PMID:19373461. |
the change in plasma gaba, glutamine and glutamate levels in fluoxetine- or s-citalopram-treated female patients with major depression. |
2009-08-18 |
2023-08-12 |
Not clear |
| Esra Küçükibrahimoğlu, Melek Z Saygin, Mecit Calişkan, Okan K Kaplan, Cüneyt Unsal, M Zafer Göre. The change in plasma GABA, glutamine and glutamate levels in fluoxetine- or S-citalopram-treated female patients with major depression. European journal of clinical pharmacology. vol 65. issue 6. 2009-08-18. PMID:19373461. |
the aim of this study was to investigate the relationship between plasma glutamate, glutamine and gamma-aminobutyric acid (gaba) levels in female patients with major depression treated with s-citalopram or fluoxetine. |
2009-08-18 |
2023-08-12 |
Not clear |