| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Tunnicliff, E Malatynsk. Central GABAergic systems and depressive illness. Neurochemical research. vol 28. issue 6. 2003-07-08. PMID:12718451. |
most of the data from direct and indirect studies are consistent with gaba involvement in depression. |
2003-07-08 |
2023-08-12 |
Not clear |
| Rosane Gomez, Carmem R Vargas, Moacir Wajner, Helena M T Barro. Lower in vivo brain extracellular GABA concentration in diabetic rats during forced swimming. Brain research. vol 968. issue 2. 2003-07-07. PMID:12663099. |
these results suggest that diabetes may change gaba homeostasis and modify behavioral responses in an animal model of depression. |
2003-07-07 |
2023-08-12 |
rat |
| I Sundström Poromaa, S Smith, M Gulinell. GABA receptors, progesterone and premenstrual dysphoric disorder. Archives of women's mental health. vol 6. issue 1. 2003-05-22. PMID:12715262. |
evidence from animal models of depression and anxiety indicate the importance of neuroactive steroid hormones and the gaba(a) receptor in the etiology and potential treatment of mood disorders. |
2003-05-22 |
2023-08-12 |
human |
| Elena Sokolova, Andrea Nistri, Rashid Giniatulli. The ATP-mediated fast current of rat dorsal root ganglion neurons is a novel effector for GABA(B) receptor activation. Neuroscience letters. vol 338. issue 3. 2003-05-07. PMID:12581826. |
because gamma-aminobutyric acid(b) (gaba(b)) agonists produce strong antinociception, the present study analyzed if gaba(b) receptors might operate through depression of p2x(3) receptors responsible for fast adenosine triphosphate (atp) currents involved in transmitting pain. |
2003-05-07 |
2023-08-12 |
rat |
| Hiroshi Mitoma, Kazuyuki Ishida, Masami Shizuka-Ikeda, Hidehiro Mizusaw. Dual impairment of GABAA- and GABAB-receptor-mediated synaptic responses by autoantibodies to glutamic acid decarboxylase. Journal of the neurological sciences. vol 208. issue 1-2. 2003-04-28. PMID:12639725. |
our results suggest that in in vitro slices, gad-a elicited the pathophysiological action of reduction in gaba release, which subsequently resulted in dual synaptic impairment in the cerebellar circuit, by depression of gaba(a) receptor (gaba(a)r)-mediated inhibitory synaptic transmissions, and attenuation of gaba(b) receptor-mediated inhibition of excitatory transmissions. |
2003-04-28 |
2023-08-12 |
rat |
| Masayuki Koshizaki, Mikito Kawamata, Steven G Shimada, Yoji Saito, J G Collin. 5-HT3 receptors partially mediate halothane depression of spinal dorsal horn sensory neurons. Anesthesia and analgesia. vol 96. issue 4. 2003-04-24. PMID:12651653. |
we recently reported that gamma-aminobutyric acid type a- and strychnine-sensitive glycine receptor systems partially mediate halothane depression of spinal dorsal horn low-threshold neurons. |
2003-04-24 |
2023-08-12 |
rat |
| Masayuki Koshizaki, Mikito Kawamata, Steven G Shimada, Yoji Saito, J G Collin. 5-HT3 receptors partially mediate halothane depression of spinal dorsal horn sensory neurons. Anesthesia and analgesia. vol 96. issue 4. 2003-04-24. PMID:12651653. |
serotonin subtype 3 (5-ht(3)) receptors belong to the same ligand-activated ion-channel family as gamma-aminobutyric acid type a- and strychnine-sensitive glycine receptors, so we examined the possible involvement of 5-ht receptor systems in halothane depression of spinal sensory neurons. |
2003-04-24 |
2023-08-12 |
rat |
| Robert I Westphalen, Hugh C Hemming. Selective depression by general anesthetics of glutamate versus GABA release from isolated cortical nerve terminals. The Journal of pharmacology and experimental therapeutics. vol 304. issue 3. 2003-04-21. PMID:12604696. |
selective depression by general anesthetics of glutamate versus gaba release from isolated cortical nerve terminals. |
2003-04-21 |
2023-08-12 |
rat |
| Jeffry S Isaacson, Harald Vitte. GABA(B) receptors inhibit dendrodendritic transmission in the rat olfactory bulb. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 6. 2003-04-17. PMID:12657661. |
in addition to reducing the amplitude of granule-cell-evoked ipscs, baclofen causes a change from paired-pulse depression to paired-pulse facilitation, suggesting that gaba(b) receptors modulate gaba release from granule cells. |
2003-04-17 |
2023-08-12 |
rat |
| Shahin Akhondzadeh, Mohammad Reza Mohammadi, Ladan Kashan. Potentiation of muscimol-induced long-term depression by benzodiazepines but not zolpidem. Progress in neuro-psychopharmacology & biological psychiatry. vol 26. issue 6. 2003-03-26. PMID:12452540. |
a novel protocol for inducing long-term synaptic depression through activation of gamma-aminobutyric acid (gaba(a)) receptors in the hippocampal slices has been recently reported. |
2003-03-26 |
2023-08-12 |
rat |
| Zhiguo Chu, John J Hablit. GABA(B) receptor-mediated heterosynaptic depression of excitatory synaptic transmission in rat frontal neocortex. Brain research. vol 959. issue 1. 2003-03-17. PMID:12480156. |
gaba(b) receptor-mediated heterosynaptic depression of excitatory synaptic transmission in rat frontal neocortex. |
2003-03-17 |
2023-08-12 |
rat |
| Zhiguo Chu, John J Hablit. GABA(B) receptor-mediated heterosynaptic depression of excitatory synaptic transmission in rat frontal neocortex. Brain research. vol 959. issue 1. 2003-03-17. PMID:12480156. |
brief stimulus trains induced a progressive depression that was insensitive to gaba(b) antagonists. |
2003-03-17 |
2023-08-12 |
rat |
| J González-Maeso, R Rodríguez-Puertas, J J Meana, J A García-Sevilla, J Guimó. Neurotransmitter receptor-mediated activation of G-proteins in brains of suicide victims with mood disorders: selective supersensitivity of alpha(2A)-adrenoceptors. Molecular psychiatry. vol 7. issue 7. 2003-02-25. PMID:12192620. |
concentration-response curves of the [(35)s]gtpgammas binding stimulation by selective agonists of alpha(2)-adrenoceptors, 5-ht(1a) serotonin, mu-opioid, gaba(b), and cholinergic muscarinic receptors were performed in frontal cortical membranes from 28 suicide victims with major depression or bipolar disorder and 28 subjects who were matched for gender, age and postmortem delay. |
2003-02-25 |
2023-08-12 |
human |
| Robert I Westphalen, Hugh C Hemming. Effects of isoflurane and propofol on glutamate and GABA transporters in isolated cortical nerve terminals. Anesthesiology. vol 98. issue 2. 2003-02-25. PMID:12552195. |
depression of glutamate-mediated excitatory transmission and potentiation of gamma-aminobutyric acid (gaba)-mediated inhibitory transmission appear to be primary mechanisms by which general anesthetics produce anesthesia. |
2003-02-25 |
2023-08-12 |
Not clear |
| Tatsuya Sasaki, Jun Sakuma, Tsuyoshi Ichikawa, Masato Matsumoto, Pankaj Tiwari, Wise Young, Namio Kodam. Effects of methylprednisolone on axonal depression induced by hypoxia, gamma-aminobutyric acid, and (+/-)-8-hydroxy-dipropylaminotetralin hydrobromide. Neurosurgery. vol 51. issue 6. 2003-01-17. PMID:12445354. |
effects of methylprednisolone on axonal depression induced by hypoxia, gamma-aminobutyric acid, and (+/-)-8-hydroxy-dipropylaminotetralin hydrobromide. |
2003-01-17 |
2023-08-12 |
Not clear |
| Tatsuya Sasaki, Jun Sakuma, Tsuyoshi Ichikawa, Masato Matsumoto, Pankaj Tiwari, Wise Young, Namio Kodam. Effects of methylprednisolone on axonal depression induced by hypoxia, gamma-aminobutyric acid, and (+/-)-8-hydroxy-dipropylaminotetralin hydrobromide. Neurosurgery. vol 51. issue 6. 2003-01-17. PMID:12445354. |
we sought to confirm the effects of methylprednisolone (mp) on axonal depression induced by hypoxia, gamma-aminobutyric acid (gaba), and (+/-)-8-hydroxy-dipropylaminotetralin hydrobromide (8-oh-dpat). |
2003-01-17 |
2023-08-12 |
Not clear |
| Eleonora Palma, Vincenzo Esposito, Anna Maria Mileo, Giancarlo Di Gennaro, Pierpaolo Quarato, Felice Giangaspero, Ciriaco Scoppetta, Paolo Onorati, Flavia Trettel, Ricardo Miledi, Fabrizio Euseb. Expression of human epileptic temporal lobe neurotransmitter receptors in Xenopus oocytes: An innovative approach to study epilepsy. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 23. 2003-01-15. PMID:12409614. |
our findings are in accord with the concept that both a depression of gaba inhibition and a dysfunction of the kai-receptor system maintain a high neuronal excitability that results in epileptic seizures. |
2003-01-15 |
2023-08-12 |
human |
| Joachim Behr, Christine Gebhardt, Uwe Heinemann, Istvan Mod. Kindling enhances kainate receptor-mediated depression of GABAergic inhibition in rat granule cells. The European journal of neuroscience. vol 16. issue 5. 2002-12-09. PMID:12372022. |
the observation that kainate receptor activation altered paired-pulse depression and reduced the frequency of ttx-insensitive miniature ipscs without affecting their amplitude is consistent with a presynaptic action on the inhibitory terminal to reduce gaba release. |
2002-12-09 |
2023-08-12 |
rat |
| Joachim Behr, Christine Gebhardt, Uwe Heinemann, Istvan Mod. Kindling enhances kainate receptor-mediated depression of GABAergic inhibition in rat granule cells. The European journal of neuroscience. vol 16. issue 5. 2002-12-09. PMID:12372022. |
consistently, the inhibitory effect on evoked ipscs was not affected by the presence of the gabab receptor antagonist, cgp55845a, thus excluding a depression by an enhanced release of gaba acting on presynaptic gabab receptors. |
2002-12-09 |
2023-08-12 |
rat |
| Gael Daoudal, Yasuhiro Hanada, Dominique Debann. Bidirectional plasticity of excitatory postsynaptic potential (EPSP)-spike coupling in CA1 hippocampal pyramidal neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 22. 2002-12-09. PMID:12391303. |
e-s depression is input-specific and is expressed in the presence of gamma-aminobutyric acid type a and b receptor antagonists. |
2002-12-09 |
2023-08-12 |
Not clear |