| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sébastien Lenglet, Fabrizio Montecucco, Adam Denes, Graham Coutts, Emmanuel Pinteaux, François Mach, Karl Schaller, Yvan Gasche, Jean-Christophe Copi. Recombinant tissue plasminogen activator enhances microglial cell recruitment after stroke in mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 34. issue 5. 2014-06-17. PMID:24473480. |
recombinant tissue plasminogen activator enhances microglial cell recruitment after stroke in mice. |
2014-06-17 |
2023-08-12 |
mouse |
| Sébastien Lenglet, Fabrizio Montecucco, Adam Denes, Graham Coutts, Emmanuel Pinteaux, François Mach, Karl Schaller, Yvan Gasche, Jean-Christophe Copi. Recombinant tissue plasminogen activator enhances microglial cell recruitment after stroke in mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 34. issue 5. 2014-06-17. PMID:24473480. |
in conclusion, we report for the first time that rtpa amplified microglia recruitment early after stroke in association with a rapid ccl3 production. |
2014-06-17 |
2023-08-12 |
mouse |
| Ye Jin, Koichi Sato, Ayaka Tobo, Chihiro Mogi, Masayuki Tobo, Naoya Murata, Satoshi Ishii, Dong-Soon Im, Fumikazu Okajim. Inhibition of interleukin-1β production by extracellular acidification through the TDAG8/cAMP pathway in mouse microglia. Journal of neurochemistry. vol 129. issue 4. 2014-06-15. PMID:24447140. |
interleukin-1β (il-1β) is released from activated microglia and involved in the neurodegeneration of acute and chronic brain disorders, such as stroke and alzheimer's disease, in which extracellular acidification has been shown to occur. |
2014-06-15 |
2023-08-12 |
mouse |
| Haixia Hu, Zuanfang Li, Xiaoqin Zhu, Ruhui Lin, Lidian Che. Salidroside Reduces Cell Mobility via NF- κ B and MAPK Signaling in LPS-Induced BV2 Microglial Cells. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2014-05-27. PMID:24864151. |
the unregulated activation of microglia following stroke results in the production of toxic factors that propagate secondary neuronal injury. |
2014-05-27 |
2023-08-13 |
Not clear |
| Robert Bronstein, Luisa Torres, Jillian C Nissen, Stella E Tsirk. Culturing microglia from the neonatal and adult central nervous system. Journal of visualized experiments : JoVE. issue 78. 2014-03-11. PMID:23962915. |
microglia can be activated and recruited to action by neuronal injury or stimulation, such as axonal damage seen in ms or ischemic brain trauma resulting from stroke. |
2014-03-11 |
2023-08-12 |
Not clear |
| Stephen D Skaper, Laura Facci, Pietro Giust. Intracellular ion channel CLIC1: involvement in microglia-mediated β-amyloid peptide(1-42) neurotoxicity. Neurochemical research. vol 38. issue 9. 2014-03-10. PMID:23743620. |
microglia can exacerbate central nervous system disorders, including stroke and chronic progressive neurodegenerative diseases such as alzheimer disease. |
2014-03-10 |
2023-08-12 |
Not clear |
| Han-Ning Chuang, Denise van Rossum, Dirk Sieger, Laila Siam, Florian Klemm, Annalen Bleckmann, Michaela Bayerlová, Katja Farhat, Jörg Scheffel, Matthias Schulz, Faramarz Dehghani, Christine Stadelmann, Uwe-Karsten Hanisch, Claudia Binder, Tobias Pukro. Carcinoma cells misuse the host tissue damage response to invade the brain. Glia. vol 61. issue 8. 2014-03-10. PMID:23832647. |
furthermore, cxcr4-regulated microglia were recruited to sites of brain injury in a zebrafish model and cxcr4 was expressed in human stroke patients, suggesting a conserved role in damage responses to various types of brain injuries. |
2014-03-10 |
2023-08-12 |
human |
| Ting Li, Shengru Pang, Yongping Yu, Xiaoqian Wu, Jing Guo, Shengxiang Zhan. Proliferation of parenchymal microglia is the main source of microgliosis after ischaemic stroke. Brain : a journal of neurology. vol 136. issue Pt 12. 2014-02-10. PMID:24154617. |
proliferation of parenchymal microglia is the main source of microgliosis after ischaemic stroke. |
2014-02-10 |
2023-08-12 |
Not clear |
| Ting Li, Shengru Pang, Yongping Yu, Xiaoqian Wu, Jing Guo, Shengxiang Zhan. Proliferation of parenchymal microglia is the main source of microgliosis after ischaemic stroke. Brain : a journal of neurology. vol 136. issue Pt 12. 2014-02-10. PMID:24154617. |
stroke induces rapid activation and expansion of microglia, but the main source of microgliosis is controversial. |
2014-02-10 |
2023-08-12 |
Not clear |
| Ting Li, Shengru Pang, Yongping Yu, Xiaoqian Wu, Jing Guo, Shengxiang Zhan. Proliferation of parenchymal microglia is the main source of microgliosis after ischaemic stroke. Brain : a journal of neurology. vol 136. issue Pt 12. 2014-02-10. PMID:24154617. |
in contrast, reactive microglia were recruited to the ischaemic area continuously during the first week after stroke induction. |
2014-02-10 |
2023-08-12 |
Not clear |
| Ting Li, Shengru Pang, Yongping Yu, Xiaoqian Wu, Jing Guo, Shengxiang Zhan. Proliferation of parenchymal microglia is the main source of microgliosis after ischaemic stroke. Brain : a journal of neurology. vol 136. issue Pt 12. 2014-02-10. PMID:24154617. |
together, these results indicated that cx3cr1(gfp/+) infiltrating cells and reactive microglia represented two distinct populations of cells with different functions and therapeutic potentials for the treatment of stroke. |
2014-02-10 |
2023-08-12 |
Not clear |
| Xian Nan Tang, Zhen Zheng, Midori A Yenar. Bone marrow chimeras in the study of experimental stroke. Translational stroke research. vol 3. issue 3. 2014-01-29. PMID:24323809. |
inflammation is known to contribute to stroke evolution, and poststroke immune responses have been documented to emanate from the brain via microglia. |
2014-01-29 |
2023-08-12 |
Not clear |
| Åsa Persson, Ahmed Osman, Hayde Bolouri, Carina Mallard, H Georg Kuh. Radixin expression in microglia after cortical stroke lesion. Glia. vol 61. issue 5. 2013-12-16. PMID:23440885. |
radixin expression in microglia after cortical stroke lesion. |
2013-12-16 |
2023-08-12 |
Not clear |
| Åsa Persson, Ahmed Osman, Hayde Bolouri, Carina Mallard, H Georg Kuh. Radixin expression in microglia after cortical stroke lesion. Glia. vol 61. issue 5. 2013-12-16. PMID:23440885. |
the specific location of radixin(+) cells in the peri-infarct region and in microglia suggests a role for radixin in microglial activation after stroke. |
2013-12-16 |
2023-08-12 |
Not clear |
| Sonja Johann, Cordian Beye. Neuroprotection by gonadal steroid hormones in acute brain damage requires cooperation with astroglia and microglia. The Journal of steroid biochemistry and molecular biology. vol 137. 2013-12-13. PMID:23196064. |
in this article, we strive for a better comprehension of the mutual reaction between these steroid hormones and the two major glial cell types involved in the maintenance of brain homeostasis, astroglia and microglia, during acute traumatic brain injuries such as stroke and hypoxia. |
2013-12-13 |
2023-08-12 |
Not clear |
| Mathias Gelderblom, Melanie Neumann, Peter Ludewig, Christian Bernreuther, Susanne Krasemann, Priyadharshini Arunachalam, Christian Gerloff, Markus Glatzel, Tim Magnu. Deficiency in serine protease inhibitor neuroserpin exacerbates ischemic brain injury by increased postischemic inflammation. PloS one. vol 8. issue 5. 2013-11-22. PMID:23658802. |
microglia are the innate immune cells of the central nervous system and the first immune cells to become activated in stroke. |
2013-11-22 |
2023-08-12 |
mouse |
| Cai Song, Ye Zhang, Yilong Don. Acute and subacute IL-1β administrations differentially modulate neuroimmune and neurotrophic systems: possible implications for neuroprotection and neurodegeneration. Journal of neuroinflammation. vol 10. 2013-11-05. PMID:23651534. |
in alzheimer's disease, stroke and brain injuries, activated microglia can release proinflammatory cytokines, such as interleukin (il)-1β. |
2013-11-05 |
2023-08-12 |
Not clear |
| Francisco J Ortega, Jukka Jolkkonen, Manuel J Rodrígue. Microglia is an active player in how glibenclamide improves stroke outcome. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 33. issue 7. 2013-09-06. PMID:23632971. |
microglia is an active player in how glibenclamide improves stroke outcome. |
2013-09-06 |
2023-08-12 |
Not clear |
| B-S Liu, R Ferreira, S Lively, L C Schlichte. Microglial SK3 and SK4 currents and activation state are modulated by the neuroprotective drug, riluzole. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 8. issue 1. 2013-08-16. PMID:22527636. |
microglia monitor the cns for 'danger' signals after acute injury, such as stroke and trauma, and then undergo complex activation processes. |
2013-08-16 |
2023-08-12 |
rat |
| Umadevi V Wesley, Raghu Vemuganti, Emine R Ayvaci, Robert J Dempse. Galectin-3 enhances angiogenic and migratory potential of microglial cells via modulation of integrin linked kinase signaling. Brain research. vol 1496. 2013-08-12. PMID:23246924. |
taken together, our studies indicate that gal-3 contributes to angiogenesis and microglia migration that may have implications in post stroke repair. |
2013-08-12 |
2023-08-12 |
human |