| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Bravo, C J Maturana, T Pelissier, A Hernández, L Constandi. Interactions of pannexin 1 with NMDA and P2X7 receptors in central nervous system pathologies: Possible role on chronic pain. Pharmacological research. vol 101. 2016-06-10. PMID:26211949. |
in the central nervous system (cns) panx1 is expressed in neurons, astrocytes and microglia, participating in the pathophysiology of some cns diseases, such as epilepsy, anoxic depolarization after stroke and neuroinflammation. |
2016-06-10 |
2023-08-13 |
Not clear |
| Soonmi Won, Jae-Kyung Lee, Donald G Stei. Recombinant tissue plasminogen activator promotes, and progesterone attenuates, microglia/macrophage M1 polarization and recruitment of microglia after MCAO stroke in rats. Brain, behavior, and immunity. vol 49. 2016-06-07. PMID:26093305. |
recombinant tissue plasminogen activator promotes, and progesterone attenuates, microglia/macrophage m1 polarization and recruitment of microglia after mcao stroke in rats. |
2016-06-07 |
2023-08-13 |
rat |
| Katja Derkow, Christina Krüger, Paul Dembny, Seija Lehnard. Microglia Induce Neurotoxic IL-17+ γδ T Cells Dependent on TLR2, TLR4, and TLR9 Activation. PloS one. vol 10. issue 8. 2016-05-17. PMID:26288016. |
both il-17+ γδ t cells and microglia, the major resident immune cells of the brain, are involved in various cns disorders such as multiple sclerosis and stroke. |
2016-05-17 |
2023-08-13 |
Not clear |
| Rodney M Ritzel, Anita R Patel, Jeremy M Grenier, Joshua Crapser, Rajkumar Verma, Evan R Jellison, Louise D McCulloug. Functional differences between microglia and monocytes after ischemic stroke. Journal of neuroinflammation. vol 12. 2016-05-03. PMID:26022493. |
the brain's initial innate response to stroke is primarily mediated by microglia, the resident macrophage of the cns. |
2016-05-03 |
2023-08-13 |
Not clear |
| Nicoletta Charolidi, Tom Schilling, Claudia Ede. Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice. PloS one. vol 10. issue 5. 2016-04-27. PMID:26011191. |
brain tissue damage following stroke or traumatic brain injury is accompanied by neuroinflammatory processes, while microglia play a central role in causing and regulating neuroinflammation via production of proinflammatory substances, including cytokines and chemokines. |
2016-04-27 |
2023-08-13 |
mouse |
| Jie Pan, Jia-li Jin, Hui-ming Ge, Kai-lin Yin, Xiang Chen, Li-juan Han, Yan Chen, Lai Qian, Xiao-xi Li, Yun X. Malibatol A regulates microglia M1/M2 polarization in experimental stroke in a PPARγ-dependent manner. Journal of neuroinflammation. vol 12. 2016-03-07. PMID:25889216. |
malibatol a regulates microglia m1/m2 polarization in experimental stroke in a pparγ-dependent manner. |
2016-03-07 |
2023-08-13 |
Not clear |
| Jojanneke H J Huck, Dorette Freyer, Chotima Böttcher, Mihovil Mladinov, Claudia Muselmann-Genschow, Mareike Thielke, Nadine Gladow, Dana Bloomquist, Philipp Mergenthaler, Josef Prille. De novo expression of dopamine D2 receptors on microglia after stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 35. issue 11. 2016-02-16. PMID:26104289. |
de novo expression of dopamine d2 receptors on microglia after stroke. |
2016-02-16 |
2023-08-13 |
mouse |
| Bastian Zinnhardt, Thomas Viel, Lydia Wachsmuth, Alexis Vrachimis, Stefan Wagner, Hans-Jörg Breyholz, Andreas Faust, Sven Hermann, Klaus Kopka, Cornelius Faber, Frédéric Dollé, Sabina Pappata, Anna M Planas, Bertrand Tavitian, Michael Schäfers, Lydia M Sorokin, Michael T Kuhlmann, Andreas H Jacob. Multimodal imaging reveals temporal and spatial microglia and matrix metalloproteinase activity after experimental stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 35. issue 11. 2016-02-16. PMID:26126867. |
multimodal imaging reveals temporal and spatial microglia and matrix metalloproteinase activity after experimental stroke. |
2016-02-16 |
2023-08-13 |
Not clear |
| Bastian Zinnhardt, Thomas Viel, Lydia Wachsmuth, Alexis Vrachimis, Stefan Wagner, Hans-Jörg Breyholz, Andreas Faust, Sven Hermann, Klaus Kopka, Cornelius Faber, Frédéric Dollé, Sabina Pappata, Anna M Planas, Bertrand Tavitian, Michael Schäfers, Lydia M Sorokin, Michael T Kuhlmann, Andreas H Jacob. Multimodal imaging reveals temporal and spatial microglia and matrix metalloproteinase activity after experimental stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 35. issue 11. 2016-02-16. PMID:26126867. |
activation of microglia and matrix metalloproteinases (mmps) is involved in positively and negatively affecting stroke outcome. |
2016-02-16 |
2023-08-13 |
Not clear |
| Cong-Yuan Xia, Shuai Zhang, Yan Gao, Zhen-Zhen Wang, Nai-Hong Che. Selective modulation of microglia polarization to M2 phenotype for stroke treatment. International immunopharmacology. vol 25. issue 2. 2016-01-04. PMID:25704852. |
selective modulation of microglia polarization to m2 phenotype for stroke treatment. |
2016-01-04 |
2023-08-13 |
Not clear |
| Jong-Youl Kim, Nuri Kim, Midori A Yenar. Mechanisms and potential therapeutic applications of microglial activation after brain injury. CNS neuroscience & therapeutics. vol 21. issue 4. 2015-12-09. PMID:25475659. |
as the resident immune cells of the central nervous system, microglia rapidly respond to brain insults, including stroke and traumatic brain injury. |
2015-12-09 |
2023-08-13 |
Not clear |
| Jongman Yoo, Jin-Ju Seo, Jang-Hyeon Eom, Dong-Youn Hwan. Enhanced recovery from chronic ischemic injury by bone marrow cells in a rat model of ischemic stroke. Cell transplantation. vol 24. issue 2. 2015-11-16. PMID:24152766. |
based on the reported anti-inflammatory role of cd25(+) regulatory t-cells in acute experimental stroke, we propose a working model delineating the positive effects of bmc transplantation during the chronic phase of stroke; infiltrating bmcs (mostly cd25(+) cells) reduce activated microglia, which leads to enhanced neural proliferation and enhanced recovery from neuronal damage in this rat model of chronic stroke. |
2015-11-16 |
2023-08-12 |
rat |
| F Sohrabji, M William. Stroke neuroprotection: oestrogen and insulin-like growth factor-1 interactions and the role of microglia. Journal of neuroendocrinology. vol 25. issue 11. 2015-10-23. PMID:23763366. |
stroke neuroprotection: oestrogen and insulin-like growth factor-1 interactions and the role of microglia. |
2015-10-23 |
2023-08-12 |
Not clear |
| F Sohrabji, M William. Stroke neuroprotection: oestrogen and insulin-like growth factor-1 interactions and the role of microglia. Journal of neuroendocrinology. vol 25. issue 11. 2015-10-23. PMID:23763366. |
here, we summarise the evidence that oestrogen-mediated neuroprotection is critically dependent on igf-1 signalling, and specifically focus on microglia as the source of igf-1 and the locus of oestrogen-igf-1 interactions in stroke neuroprotection. |
2015-10-23 |
2023-08-12 |
Not clear |
| Youngjeon Lee, Sang-Rae Lee, Sung S Choi, Hyeon-Gu Yeo, Kyu-Tae Chang, Hong J Le. Therapeutically targeting neuroinflammation and microglia after acute ischemic stroke. BioMed research international. vol 2014. 2015-10-06. PMID:25089266. |
in this review, we discuss the role of microglial mediators in acute ischemic stroke and elaborate on preclinical and clinical studies focused on microglia in stroke models. |
2015-10-06 |
2023-08-13 |
Not clear |
| Jens Neumann, Monika Riek-Burchardt, Josephine Herz, Thorsten R Doeppner, Rebecca König, Heiko Hütten, Eloho Etemire, Linda Männ, Anika Klingberg, Thomas Fischer, Michael W Görtler, Hans-Jochen Heinze, Peter Reichardt, Burkhart Schraven, Dirk M Hermann, Klaus G Reymann, Matthias Gunze. Very-late-antigen-4 (VLA-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental stroke. Acta neuropathologica. vol 129. issue 2. 2015-09-21. PMID:25391494. |
very-late-antigen-4 (vla-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental stroke. |
2015-09-21 |
2023-08-13 |
mouse |
| Jens Neumann, Monika Riek-Burchardt, Josephine Herz, Thorsten R Doeppner, Rebecca König, Heiko Hütten, Eloho Etemire, Linda Männ, Anika Klingberg, Thomas Fischer, Michael W Görtler, Hans-Jochen Heinze, Peter Reichardt, Burkhart Schraven, Dirk M Hermann, Klaus G Reymann, Matthias Gunze. Very-late-antigen-4 (VLA-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental stroke. Acta neuropathologica. vol 129. issue 2. 2015-09-21. PMID:25391494. |
here, we have used intravital two-photon microscopy to document neutrophils and brain-resident microglia in mice after induction of experimental stroke. |
2015-09-21 |
2023-08-13 |
mouse |
| Valérie Jolivel, Frank Bicker, Fabien Binamé, Robert Ploen, Stefanie Keller, René Gollan, Betty Jurek, Jérôme Birkenstock, Laura Poisa-Beiro, Julia Bruttger, Verena Opitz, Serge C Thal, Ari Waisman, Tobias Bäuerle, Michael K Schäfer, Frauke Zipp, Mirko H H Schmid. Perivascular microglia promote blood vessel disintegration in the ischemic penumbra. Acta neuropathologica. vol 129. issue 2. 2015-09-21. PMID:25500713. |
the contribution of microglia to ischemic cortical stroke is of particular therapeutic interest because of the impact on the survival of brain tissue in the ischemic penumbra, a region that is potentially salvable upon a brain infarct. |
2015-09-21 |
2023-08-13 |
mouse |
| Valérie Jolivel, Frank Bicker, Fabien Binamé, Robert Ploen, Stefanie Keller, René Gollan, Betty Jurek, Jérôme Birkenstock, Laura Poisa-Beiro, Julia Bruttger, Verena Opitz, Serge C Thal, Ari Waisman, Tobias Bäuerle, Michael K Schäfer, Frauke Zipp, Mirko H H Schmid. Perivascular microglia promote blood vessel disintegration in the ischemic penumbra. Acta neuropathologica. vol 129. issue 2. 2015-09-21. PMID:25500713. |
to study the role of microglia in cortical stroke and blood vessel stability, cx3cr1(+/gfp) mice were subjected to transient middle cerebral artery occlusion and then microglia were investigated using time-lapse two-photon microscopy in vivo. |
2015-09-21 |
2023-08-13 |
mouse |
| Valérie Jolivel, Frank Bicker, Fabien Binamé, Robert Ploen, Stefanie Keller, René Gollan, Betty Jurek, Jérôme Birkenstock, Laura Poisa-Beiro, Julia Bruttger, Verena Opitz, Serge C Thal, Ari Waisman, Tobias Bäuerle, Michael K Schäfer, Frauke Zipp, Mirko H H Schmid. Perivascular microglia promote blood vessel disintegration in the ischemic penumbra. Acta neuropathologica. vol 129. issue 2. 2015-09-21. PMID:25500713. |
soon after reperfusion, microglia became activated in the stroke penumbra and started to expand cellular protrusions towards adjacent blood vessels. |
2015-09-21 |
2023-08-13 |
mouse |