| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alexandra Heyden, Mihai-Constantin S Ionescu, Stefano Romorini, Bettina Kracht, Veronica Ghiglieri, Paolo Calabresi, Constanze Seidenbecher, Frank Angenstein, Eckart D Gundelfinge. Hippocampal enlargement in Bassoon-mutant mice is associated with enhanced neurogenesis, reduced apoptosis, and abnormal BDNF levels. Cell and tissue research. vol 346. issue 1. 2012-02-21. PMID:21935677. |
hippocampal enlargement in bassoon-mutant mice is associated with enhanced neurogenesis, reduced apoptosis, and abnormal bdnf levels. |
2012-02-21 |
2023-08-12 |
mouse |
| Alexandra Heyden, Mihai-Constantin S Ionescu, Stefano Romorini, Bettina Kracht, Veronica Ghiglieri, Paolo Calabresi, Constanze Seidenbecher, Frank Angenstein, Eckart D Gundelfinge. Hippocampal enlargement in Bassoon-mutant mice is associated with enhanced neurogenesis, reduced apoptosis, and abnormal BDNF levels. Cell and tissue research. vol 346. issue 1. 2012-02-21. PMID:21935677. |
these data show that hippocampal overgrowth in bassoon-mutant mice arises from a dysregulation of neurogenesis and apoptosis that might be associated with unbalanced bdnf levels. |
2012-02-21 |
2023-08-12 |
mouse |
| Xiao-Lu Cao, Xia-Min Hu, Jia-Qing Hu, Wen-Xia Zhen. Myocardin-related transcription factor-A promoting neuronal survival against apoptosis induced by hypoxia/ischemia. Brain research. vol 1385. 2012-02-14. PMID:21333636. |
in addition, we also found that bdnf neuroprotection on apoptosis induced by hypoxia-trophic withdrawal was not only inhibited by ly29004 and pd98059 but also partially blocked by transfection of dominant-negative mrtf-a in cortical neurons via enhancing the expression of anti-apoptotic gene-mcl-1, suggesting a downstream neuroprotective mechanism to bdnf neuroprotection on apoptosis. |
2012-02-14 |
2023-08-12 |
rat |
| Evangelos Delivopoulos, Alan F Murra. Controlled adhesion and growth of long term glial and neuronal cultures on Parylene-C. PloS one. vol 6. issue 9. 2012-02-10. PMID:21966523. |
neuronal apoptosis, often associated with the use of ara-c, is mitigated by the addition of brain derived neurotrophic factor (bdnf). |
2012-02-10 |
2023-08-12 |
rat |
| Min Dai, Xiao-Bo Xia, Si-Qi Xion. BDNF regulates GLAST and glutamine synthetase in mouse retinal Müller cells. Journal of cellular physiology. vol 227. issue 2. 2012-01-30. PMID:21448920. |
cocl(2) alone or combined with bdnf did not induce apoptosis. |
2012-01-30 |
2023-08-12 |
mouse |
| Dawei Guo, Xuezhong Hou, Hongbin Zhang, Wenyu Sun, Lei Zhu, Jian Liang, Xiaofeng Jian. More expressions of BDNF and TrkB in multiple hepatocellular carcinoma and anti-BDNF or K252a induced apoptosis, supressed invasion of HepG2 and HCCLM3 cells. Journal of experimental & clinical cancer research : CR. vol 30. 2012-01-17. PMID:21999199. |
more expressions of bdnf and trkb in multiple hepatocellular carcinoma and anti-bdnf or k252a induced apoptosis, supressed invasion of hepg2 and hcclm3 cells. |
2012-01-17 |
2023-08-12 |
human |
| Marta Kubera, Ewa Obuchowicz, Lisa Goehler, Joanna Brzeszcz, Michael Mae. In animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 35. issue 3. 2012-01-06. PMID:20828592. |
external stress-induced depression-like behaviors are associated with a) increased interleukin-(il)1β, tumor necrosis factor-α, il-6, nuclear factor κb, cyclooxygenase-2, expression of toll-like receptors and lipid peroxidation; b) antineurogenic effects and reduced brain-derived neurotrophic factor (bdnf) levels; and c) apoptosis with reduced levels of bcl-2 and bag1 (bcl-2 associated athanogene 1), and increased levels of caspase-3. |
2012-01-06 |
2023-08-12 |
Not clear |
| Yansong Wang, Xifan Me, Li Zhang, Gang L. Supplement moderate zinc as an effective treatment for spinal cord injury. Medical hypotheses. vol 77. issue 4. 2011-12-29. PMID:21752551. |
zinc plays an important role in regulating the expression of brain-derived neurotrophic factor (bdnf) in nervous system, which can improve the pathological state of neurons and promote regeneration of injured neurons, reduce neuronal apoptosis. |
2011-12-29 |
2023-08-12 |
Not clear |
| Ashutosh, Wei Kou, Robin Cotter, Kathleen Borgmann, Li Wu, Raisa Persidsky, Namita Sakhuja, Anuja Ghorpad. CXCL8 protects human neurons from amyloid-β-induced neurotoxicity: relevance to Alzheimer's disease. Biochemical and biophysical research communications. vol 412. issue 4. 2011-11-22. PMID:21840299. |
although cxcl8-alone did not alter neuronal survival, it did inhibit aβ-induced neuronal apoptosis and increased neuronal brain-derived neurotrophic factor (bdnf) production. |
2011-11-22 |
2023-08-12 |
human |
| Zhen-Hong Zhu, You-Shui Gao, Bing-Fang Zeng, Chang-Qing Zhan. The effect of dexamethasone and hypoxic stress on MC3T3-E1 cells. Frontiers in bioscience (Landmark edition). vol 16. 2011-10-03. PMID:21622206. |
the mitochondrial membrane potential collapsed, and the inhibitor brain- derived neurotrophic factor (bdnf) conferred effective protection against apoptosis. |
2011-10-03 |
2023-08-12 |
Not clear |
| F Truzzi, A Marconi, P Atzei, M C Panza, R Lotti, K Dallaglio, R Tiberio, E Palazzo, C Vaschieri, C Pincell. p75 neurotrophin receptor mediates apoptosis in transit-amplifying cells and its overexpression restores cell death in psoriatic keratinocytes. Cell death and differentiation. vol 18. issue 6. 2011-08-22. PMID:21151024. |
brain-derived neurotrophic factor (bdnf) or neurotrophin-4 (nt-4), which signals through p75ntr, induces keratinocyte apoptosis, whereas β-amyloid, a ligand for p75ntr, triggers caspase-3 activation to a greater extent in p75ntr transfected cells. |
2011-08-22 |
2023-08-12 |
human |
| F Truzzi, A Marconi, P Atzei, M C Panza, R Lotti, K Dallaglio, R Tiberio, E Palazzo, C Vaschieri, C Pincell. p75 neurotrophin receptor mediates apoptosis in transit-amplifying cells and its overexpression restores cell death in psoriatic keratinocytes. Cell death and differentiation. vol 18. issue 6. 2011-08-22. PMID:21151024. |
bdnf or β-amyloid fail to induce apoptosis in psoriatic ta cells, and p75ntr retroviral infection restores bdnf- or β-amyloid-induced apoptosis in psoriatic keratinocytes. |
2011-08-22 |
2023-08-12 |
human |
| Chenchen Niu, Henry K Yi. Neuroprotective signaling mechanisms of telomerase are regulated by brain-derived neurotrophic factor in rat spinal cord motor neurons. Journal of neuropathology and experimental neurology. vol 70. issue 7. 2011-08-22. PMID:21666495. |
spinal cord motor neurons with higher telomerase levels induced by bdnf became more resistant to apoptosis; survival of smns that overexpressed the catalytic protein component of telomerase with reverse transcriptase activity was also enhanced against apoptosis. |
2011-08-22 |
2023-08-12 |
rat |
| Valeriya Avdoshina, Alfredo Garzino-Demo, Alessia Bachis, Maria C G Monaco, Pauline M Maki, Rochelle E Tractenberg, Chenglong Liu, Mary A Young, Italo Mocchett. HIV-1 decreases the levels of neurotrophins in human lymphocytes. AIDS (London, England). vol 25. issue 8. 2011-07-26. PMID:21422985. |
our results support the hypothesis that reduced levels of bdnf may be a risk factor for t-cell apoptosis and for neurological complications associated with hiv-1 infection. |
2011-07-26 |
2023-08-12 |
human |
| Meizhu Zheng, Chunming Liu, Fengguang Pan, Dongfang Shi, Fengshan Ma, Yuchi Zhang, Yujing Zhan. Protective effects of flavonoid extract from Apocynum venetum leaves against corticosterone-induced neurotoxicity in PC12 cells. Cellular and molecular neurobiology. vol 31. issue 3. 2011-07-22. PMID:21170580. |
the results showed that av extract (25, 50, and 100 μg/ml) increased the a490 nm values, but decreased ldh release and ca(2+) concentration, suppressed the apoptosis of pc12 cells and up-regulated bdnf and map4 transcript abundances compared with the corresponding corticosterone-treated group. |
2011-07-22 |
2023-08-12 |
Not clear |
| José M Frade, Noelia López-Sánche. A novel hypothesis for Alzheimer disease based on neuronal tetraploidy induced by p75 (NTR). Cell cycle (Georgetown, Tex.). vol 9. issue 10. 2011-05-03. PMID:20436277. |
in contrast, bdnf inhibits g2/m transition in tetraploid rgcs, preventing their death by apoptosis. |
2011-05-03 |
2023-08-12 |
Not clear |
| Jing Huang, Chun-Yan Sun, Tao Guo, Zhang-Bo Chu, Ya-Dan Wang, Yu H. [Effect of RNA interference targeting brain-derived neurotrophic factor gene on HeLa cell proliferation and apoptosis]. Zhonghua bing li xue za zhi = Chinese journal of pathology. vol 38. issue 10. 2011-03-24. PMID:20078974. |
to screen effective sequences of short hairpin rna on brain-derived neurotrophic factor (bdnf) gene and the effect of rna interference on the proliferation and apoptosis of hela cells, a cervix carcinoma cell line with high expression of bdnf. |
2011-03-24 |
2023-08-12 |
Not clear |
| Lorna C Gleeson, Katie J Ryan, Eadaoin W Griffin, Thomas J Connor, Andrew Harki. The β2-adrenoceptor agonist clenbuterol elicits neuroprotective, anti-inflammatory and neurotrophic actions in the kainic acid model of excitotoxicity. Brain, behavior, and immunity. vol 24. issue 8. 2011-01-21. PMID:20599496. |
whilst clenbuterol treatment did not significantly alter ka-induced epileptic behavior it ameliorated ka-induced apoptosis, and this neuroprotective effect was accompanied by reduced inflammatory cytokine expression, reduced expression of inos, ido, kmo and cd11b, coupled with increased bdnf and ngf expression in ka-treated rats. |
2011-01-21 |
2023-08-12 |
rat |
| Wen-Sheng Wen, Zhe Zhang, Ying Xie, Xiang Yi, Wei-Min Zhao, Zhi-Wen Xu, An-Zhou Tang, Guang-Wu Huan. [Relationship between the expression of TrkB and anoikis resistance in nasopharyngeal carcinoma line]. Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery. vol 43. issue 8. 2011-01-11. PMID:18959266. |
proliferation rate and apoptosis, that change in cells by treating the trkb inhibitor k252a and specificity ligand bdnf respectively under suspension culture, were measured by cell counting kit-8 (cck-8) assay and the flow cytometry assay. |
2011-01-11 |
2023-08-12 |
human |
| Yunfei Tan, Jinfeng Duan, Yufeng Li, Wei Ca. Effects of citalopram on serum deprivation induced PC12 cell apoptosis and BDNF expression. Die Pharmazie. vol 65. issue 11. 2011-01-10. PMID:21155393. |
effects of citalopram on serum deprivation induced pc12 cell apoptosis and bdnf expression. |
2011-01-10 |
2023-08-12 |
Not clear |