| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhitao Wang, Quanjun Deng, Xiaohui Zhang, Jianning Zhan. Treatment of injured neurons with bone marrow stem cells cotransfected by hTERT and Ad-BDNF in vitro. Journal of molecular neuroscience : MN. vol 38. issue 3. 2009-08-17. PMID:19459071. |
our data demonstrated that graft rbmscs transfected by htert and ad-bdnf could increase the expression of bdnf in injured neurons and alleviate apoptosis of the injured neurons. |
2009-08-17 |
2023-08-12 |
human |
| Zhixiong Li, Gernot Beutel, Mathias Rhein, Johann Meyer, Christian Koenecke, Thomas Neumann, Min Yang, Jürgen Krauter, Nils von Neuhoff, Michael Heuser, Helmut Diedrich, Gudrun Göhring, Ludwig Wilkens, Brigitte Schlegelberger, Arnold Ganser, Christopher Bau. High-affinity neurotrophin receptors and ligands promote leukemogenesis. Blood. vol 113. issue 9. 2009-04-10. PMID:19059881. |
activation of trka or trkb by ngf and bdnf, respectively, efficiently rescued murine myeloid cells from irradiation-induced apoptosis. |
2009-04-10 |
2023-08-12 |
human |
| Lorenzo De Santi, Loredana Cantalupo, Maristella Tassi, Donatella Raspadori, Chiara Cioni, Pasquale Annunziat. Higher expression of BDNF receptor gp145trkB is associated with lower apoptosis intensity in T cell lines in multiple sclerosis. Journal of the neurological sciences. vol 277. issue 1-2. 2009-04-02. PMID:18992902. |
higher expression of bdnf receptor gp145trkb is associated with lower apoptosis intensity in t cell lines in multiple sclerosis. |
2009-04-02 |
2023-08-12 |
human |
| R Fujita, M Ueda, K Fujiwara, H Ued. Prothymosin-alpha plays a defensive role in retinal ischemia through necrosis and apoptosis inhibition. Cell death and differentiation. vol 16. issue 2. 2009-03-16. PMID:18989338. |
treatments with anti-erythropoietin (epo) or brain-derived neurotrophic factor (bdnf) immunoglobulin g (igg) reversed protalpha-induced inhibition of apoptosis. |
2009-03-16 |
2023-08-12 |
mouse |
| M J M Bertrand, R S Kenchappa, D Andrieu, M Leclercq-Smekens, H N T Nguyen, B D Carter, F Muscatelli, P A Barker, O De Backe. NRAGE, a p75NTR adaptor protein, is required for developmental apoptosis in vivo. Cell death and differentiation. vol 15. issue 12. 2009-01-28. PMID:18772898. |
primary sympathetic neurons derived from nrage knockout mice were resistant to apoptosis induced by brain-derived neurotrophic factor (bdnf), a pro-apoptotic p75ntr ligand, and nrage-deficient sympathetic neurons show attenuated bdnf-dependent jnk activation. |
2009-01-28 |
2023-08-12 |
mouse |
| Anilkumar Pillai, Rajalakshmi Veeranan-Karmegam, Krishnan M Dhandapani, Sahebarao P Mahadi. Cystamine prevents haloperidol-induced decrease of BDNF/TrkB signaling in mouse frontal cortex. Journal of neurochemistry. vol 107. issue 4. 2009-01-15. PMID:18786174. |
in addition, in vitro experiments with mouse cortical neurons showed that cys prevented the hal-induced reduction in neuronal cell viability and bdnf protein levels, and increase in apoptosis. |
2009-01-15 |
2023-08-12 |
mouse |
| V Corsetti, G Amadoro, A Gentile, S Capsoni, M T Ciotti, M T Cencioni, A Atlante, N Canu, T T Rohn, A Cattaneo, P Calissan. Identification of a caspase-derived N-terminal tau fragment in cellular and animal Alzheimer's disease models. Molecular and cellular neurosciences. vol 38. issue 3. 2008-12-09. PMID:18511295. |
we provide biochemical evidence that a caspase(s)-cleaved nh2-terminal tau fragment of 20-22 kda, consistent with the size of the nh2 26-230aa neurotoxic fragment of tau, is generated in vitro in differentiated human sh-sy5y cells undergoing apoptosis by bdnf withdrawal or following treatment with staurosporine. |
2008-12-09 |
2023-08-12 |
mouse |
| Giorgi Kharebava, Denys Makonchuk, Katarzyna B Kalita, Jing-Juan Zheng, Michal Hetma. Requirement of 3-phosphoinositide-dependent protein kinase-1 for BDNF-mediated neuronal survival. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 44. 2008-11-18. PMID:18971483. |
in trophic-deprived cortical neurons, knockdown of endogenous pdk1 attenuated the antiapoptotic survival response to 10 ng/ml bdnf, whereas an overexpressed active mutant form of pdk1 reduced apoptosis. |
2008-11-18 |
2023-08-12 |
rat |
| Angela Berzi, C Korcan Ayata, Paola Cavalcante, Chiara Falcone, Elisabetta Candiago, Teresio Motta, Pia Bernasconi, Reinhard Hohlfeld, Renato Mantegazza, Edgar Meinl, Cinthia Farin. BDNF and its receptors in human myasthenic thymus: implications for cell fate in thymic pathology. Journal of neuroimmunology. vol 197. issue 2. 2008-11-05. PMID:18555538. |
finally, all tec dying of apoptosis expressed bdnf receptors, indicating that this neurotrophin is involved in tec turnover. |
2008-11-05 |
2023-08-12 |
human |
| Rui Chen, Junji Moriya, Jun-ichi Yamakawa, Takashi Takahashi, Qian Li, Shigeto Morimoto, Kunimitsu Iwai, Hiroyuki Sumino, Nobuo Yamaguchi, Tsugiyasu Kand. Brain atrophy in a murine model of chronic fatigue syndrome and beneficial effect of Hochu-ekki-to (TJ-41). Neurochemical research. vol 33. issue 9. 2008-10-31. PMID:18317925. |
brain-derived neurotrophic factor (bdnf) is associated with the main symptoms of chronic fatigue syndrome (cfs) and neuron apoptosis. |
2008-10-31 |
2023-08-12 |
mouse |
| Rui Chen, Junji Moriya, Jun-ichi Yamakawa, Takashi Takahashi, Qian Li, Shigeto Morimoto, Kunimitsu Iwai, Hiroyuki Sumino, Nobuo Yamaguchi, Tsugiyasu Kand. Brain atrophy in a murine model of chronic fatigue syndrome and beneficial effect of Hochu-ekki-to (TJ-41). Neurochemical research. vol 33. issue 9. 2008-10-31. PMID:18317925. |
nevertheless, no study has been performed directly to explore the relationship between cfs, bdnf and neuron apoptosis. |
2008-10-31 |
2023-08-12 |
mouse |
| Rui Chen, Junji Moriya, Jun-ichi Yamakawa, Takashi Takahashi, Qian Li, Shigeto Morimoto, Kunimitsu Iwai, Hiroyuki Sumino, Nobuo Yamaguchi, Tsugiyasu Kand. Brain atrophy in a murine model of chronic fatigue syndrome and beneficial effect of Hochu-ekki-to (TJ-41). Neurochemical research. vol 33. issue 9. 2008-10-31. PMID:18317925. |
in this model, reduced daily activity might have been associated with decreased hippocampal bdnf mrna expression, hippocampal apoptosis and brain atrophy. |
2008-10-31 |
2023-08-12 |
mouse |
| Christian Montag, Ulrike Basten, Christine Stelzel, Christian J Fiebach, Martin Reute. The BDNF Val66Met polymorphism and smoking. Neuroscience letters. vol 442. issue 1. 2008-10-14. PMID:18602452. |
bdnf represents a protein which crucially influences several processes in the cell ranging from growth to apoptosis. |
2008-10-14 |
2023-08-12 |
human |
| Tapas K Makar, David Trisler, Karna T Sura, Shireen Sultana, Niraj Patel, Christopher T Beve. Brain derived neurotrophic factor treatment reduces inflammation and apoptosis in experimental allergic encephalomyelitis. Journal of the neurological sciences. vol 270. issue 1-2. 2008-09-24. PMID:18374360. |
we have developed a novel delivery system for bdnf using transformed bone marrow stem cells (bmsc) and undertook studies of eae to determine whether the delivery of bdnf could reduce inflammation and apoptosis. |
2008-09-24 |
2023-08-12 |
mouse |
| Tapas K Makar, David Trisler, Karna T Sura, Shireen Sultana, Niraj Patel, Christopher T Beve. Brain derived neurotrophic factor treatment reduces inflammation and apoptosis in experimental allergic encephalomyelitis. Journal of the neurological sciences. vol 270. issue 1-2. 2008-09-24. PMID:18374360. |
consistent with the known mechanism of action of bdnf on apoptosis, bcl-2 and akt were increased in treated mice. |
2008-09-24 |
2023-08-12 |
mouse |
| Tapas K Makar, David Trisler, Karna T Sura, Shireen Sultana, Niraj Patel, Christopher T Beve. Brain derived neurotrophic factor treatment reduces inflammation and apoptosis in experimental allergic encephalomyelitis. Journal of the neurological sciences. vol 270. issue 1-2. 2008-09-24. PMID:18374360. |
these results suggest that the bdnf delivered by the transformed bone marrow stem cells reduced clinical severity, inflammation and apoptosis in this model. |
2008-09-24 |
2023-08-12 |
mouse |
| Tapas K Makar, David Trisler, Christopher T Bever, James E Goolsby, Karna T Sura, Shailesh Balasubramanian, Shireen Sultana, Niraj Patel, David Ford, Ishwar S Singh, Aditi Gupta, Reuben M Valenzuela, Suhayl Dhib-Jalbu. Stem cell based delivery of IFN-beta reduces relapses in experimental autoimmune encephalomyelitis. Journal of neuroimmunology. vol 196. issue 1-2. 2008-09-24. PMID:18471898. |
in addition, mice receiving ifn-beta had reduced apoptosis and increases in growth promoting factors including bdnf, cntf, pdgf and vegf. |
2008-09-24 |
2023-08-12 |
mouse |
| Anne-Laure Fauchais, Fabrice Lalloué, Marie-Claude Lise, Ahmed Boumediene, Jean-Louis Preud'homme, Elisabeth Vidal, Marie-Odile Jaubertea. Role of endogenous brain-derived neurotrophic factor and sortilin in B cell survival. Journal of immunology (Baltimore, Md. : 1950). vol 181. issue 5. 2008-09-15. PMID:18713973. |
therefore, in mature b cell lines, an autocrine bdnf production is up-regulated by stress culture conditions and exerts a modulation of apoptosis through the sortilin pathway. |
2008-09-15 |
2023-08-12 |
human |
| S Kaloustian, B P Wann, T M Bah, S A Girard, A Apostolakis, S Ishak, S Mathieu, P Ryvlin, R Godbout, G Roussea. Apoptosis time course in the limbic system after myocardial infarction in the rat. Brain research. vol 1216. 2008-09-08. PMID:18495089. |
apoptosis, i.e., caspase-3 activity and the number of terminal dutp nick-end labelling-positive cells, as well as brain-derived neurotrophic factor (bdnf) were quantitated in sham-operated controls and mi rats 1, 2 and 7 days after surgery. |
2008-09-08 |
2023-08-12 |
rat |
| Anilkumar Pillai, Krishnan M Dhandapani, Bindu A Pillai, Alvin V Terry, Sahebarao P Mahadi. Erythropoietin prevents haloperidol treatment-induced neuronal apoptosis through regulation of BDNF. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 8. 2008-09-02. PMID:17805306. |
erythropoietin prevents haloperidol treatment-induced neuronal apoptosis through regulation of bdnf. |
2008-09-02 |
2023-08-12 |
human |