| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S A Hube. T cells expressing the gamma delta T cell receptor induce apoptosis in cardiac myocytes. Cardiovascular research. vol 45. issue 3. 2000-04-13. PMID:10728379. |
t cells expressing the gamma delta t cell receptor induce apoptosis in cardiac myocytes. |
2000-04-13 |
2023-08-12 |
mouse |
| S A Hube. T cells expressing the gamma delta T cell receptor induce apoptosis in cardiac myocytes. Cardiovascular research. vol 45. issue 3. 2000-04-13. PMID:10728379. |
using an experimental murine model of this disease, previous studies have shown that myocarditis susceptibility depends upon activation of t lymphocytes expressing the gamma delta t cell receptor (tcr), and that only mouse strains which accumulate gamma delta t cells in the myocardium show apoptosis of myocytes or evidence of dilated cardiomyopathy-like disease. |
2000-04-13 |
2023-08-12 |
mouse |
| S A Hube. T cells expressing the gamma delta T cell receptor induce apoptosis in cardiac myocytes. Cardiovascular research. vol 45. issue 3. 2000-04-13. PMID:10728379. |
the objective of the present studies is to demonstrate that gamma delta t cells directly induce greater fas-dependent apoptosis of cultured myocytes than t cells expressing the alpha beta tcr. |
2000-04-13 |
2023-08-12 |
mouse |
| T Fujii, M L García-Bermejo, J L Bernabó, J Caamaño, M Ohba, T Kuroki, L Li, S H Yuspa, M G Kazaniet. Involvement of protein kinase C delta (PKCdelta) in phorbol ester-induced apoptosis in LNCaP prostate cancer cells. Lack of proteolytic cleavage of PKCdelta. The Journal of biological chemistry. vol 275. issue 11. 2000-04-12. PMID:10713064. |
involvement of protein kinase c delta (pkcdelta) in phorbol ester-induced apoptosis in lncap prostate cancer cells. |
2000-04-12 |
2023-08-12 |
Not clear |
| I Tsujio, T Tanaka, T Kudo, T Nishikawa, K Shinozaki, I Grundke-Iqbal, K Iqbal, M Taked. Inactivation of glycogen synthase kinase-3 by protein kinase C delta: implications for regulation of tau phosphorylation. FEBS letters. vol 469. issue 1. 2000-04-10. PMID:10708767. |
it is suggested that fragmentation of pkc delta during the process of apoptosis results in the phosphorylation and inactivation of gsk-3 and consequently inhibition of the phosphorylation of tau. |
2000-04-10 |
2023-08-12 |
human |
| H Louagie, P Schotte, A Vral, M Cornelissen, H Thierens, R Beyaert, L De Ridder, J Philipp. Apoptosis induced by gamma irradiation in peripheral blood mononuclear cells is not mediated by cytochrome-c release and only partially involves caspase-3-like proteases. Cell biology international. vol 23. issue 9. 2000-04-04. PMID:10728572. |
apoptosis in pbl after a 5-gy gamma irradiation, is characterized by a decrease in delta psi m, but surprisingly no release of cytochrome-c and only a weak caspase 3 activation was noticed. |
2000-04-04 |
2023-08-12 |
Not clear |
| Y Kagawa, S H Cha, K Hasegawa, T Hamamoto, H End. Regulation of energy metabolism in human cells in aging and diabetes: FoF(1), mtDNA, UCP, and ROS. Biochemical and biophysical research communications. vol 266. issue 3. 2000-02-03. PMID:10603304. |
we cultured human rho(o) cells (cells without mtdna) in synthetic media and elucidated relationships among mtdna, ndna, delta muh(+), ucps, ros, and apoptosis. |
2000-02-03 |
2023-08-12 |
human |
| Y Kagawa, S H Cha, K Hasegawa, T Hamamoto, H End. Regulation of energy metabolism in human cells in aging and diabetes: FoF(1), mtDNA, UCP, and ROS. Biochemical and biophysical research communications. vol 266. issue 3. 2000-02-03. PMID:10603304. |
ucps lower delta muh(+) and prevent ros formation and resulting apoptosis. |
2000-02-03 |
2023-08-12 |
human |
| Y Kagawa, S H Cha, K Hasegawa, T Hamamoto, H End. Regulation of energy metabolism in human cells in aging and diabetes: FoF(1), mtDNA, UCP, and ROS. Biochemical and biophysical research communications. vol 266. issue 3. 2000-02-03. PMID:10603304. |
in aged cells, delta muh(+) was reduced by the slow respiration, and this change induced apoptosis. |
2000-02-03 |
2023-08-12 |
human |
| K Roberg, U Johansson, K Ollinge. Lysosomal release of cathepsin D precedes relocation of cytochrome c and loss of mitochondrial transmembrane potential during apoptosis induced by oxidative stress. Free radical biology & medicine. vol 27. issue 11-12. 2000-01-27. PMID:10641715. |
our findings show that, during naphthazarin-induced apoptosis, lysosomal destabilization (measured as release of cathepsin d) precedes release of cytochrome c, loss of delta psi(m), and morphologic alterations. |
2000-01-27 |
2023-08-12 |
human |
| H Koriyama, Z Kouchi, T Umeda, T C Saido, T Momoi, S Ishiura, K Suzuk. Proteolytic activation of protein kinase C delta and epsilon by caspase-3 in U937 cells during chemotherapeutic agent-induced apoptosis. Cellular signalling. vol 11. issue 11. 2000-01-19. PMID:10617286. |
proteolytic activation of protein kinase c delta and epsilon by caspase-3 in u937 cells during chemotherapeutic agent-induced apoptosis. |
2000-01-19 |
2023-08-12 |
Not clear |
| K Tamura, R L Rice, P Wipf, J S Laz. Dual G1 and G2/M phase inhibition by SC-alpha alpha delta 9, a combinatorially derived Cdc25 phosphatase inhibitor. Oncogene. vol 18. issue 50. 2000-01-04. PMID:10597298. |
we propose that the sc-alpha alpha delta 9 pharmacophore could be useful in further clarifying the role of cdc25 phosphatase-dependent pathways in checkpoint control, oncogenesis, and apoptosis. |
2000-01-04 |
2023-08-12 |
Not clear |
| H Konishi, H Matsuzaki, H Takaishi, T Yamamoto, M Fukunaga, Y Ono, U Kikkaw. Opposing effects of protein kinase C delta and protein kinase B alpha on H(2)O(2)-induced apoptosis in CHO cells. Biochemical and biophysical research communications. vol 264. issue 3. 1999-12-22. PMID:10544018. |
opposing effects of protein kinase c delta and protein kinase b alpha on h(2)o(2)-induced apoptosis in cho cells. |
1999-12-22 |
2023-08-12 |
Not clear |
| H Konishi, H Matsuzaki, H Takaishi, T Yamamoto, M Fukunaga, Y Ono, U Kikkaw. Opposing effects of protein kinase C delta and protein kinase B alpha on H(2)O(2)-induced apoptosis in CHO cells. Biochemical and biophysical research communications. vol 264. issue 3. 1999-12-22. PMID:10544018. |
h(2)o(2)-induced apoptosis was enhanced in the cho cell line overproducing protein kinase c delta (pkcdelta) as judged by dna fragmentation. |
1999-12-22 |
2023-08-12 |
Not clear |
| C Oh, Y Kim, J Eun, T Yokoyama, M Kato, I Nakashim. Induction of T lymphocyte apoptosis by treatment with glycyrrhizin. The American journal of Chinese medicine. vol 27. issue 2. 1999-11-30. PMID:10467455. |
we concluded from these results that gl acts as a rather selective inducer of mature t lymphocyte apoptosis with a reduction in delta psi m potentially preceding lymphocyte death. |
1999-11-30 |
2023-08-12 |
mouse |
| J A Heibein, M Barry, B Motyka, R C Bleackle. Granzyme B-induced loss of mitochondrial inner membrane potential (Delta Psi m) and cytochrome c release are caspase independent. Journal of immunology (Baltimore, Md. : 1950). vol 163. issue 9. 1999-11-19. PMID:10528165. |
among these, the disruption of the inner mitochondrial transmembrane potential (delta psi m) and the release of cytochrome c into the cytoplasm appear to be early events in many systems, leading to the activation of caspase-3 and, subsequently, nuclear apoptosis. |
1999-11-19 |
2023-08-12 |
Not clear |
| S Wang, Z Wang, L H Boise, P Dent, S Gran. Bryostatin 1 enhances paclitaxel-induced mitochondrial dysfunction and apoptosis in human leukemia cells (U937) ectopically expressing Bcl-xL. Leukemia. vol 13. issue 10. 1999-11-03. PMID:10516758. |
overexpression of bcl-xl blocked various aspects of paclitaxel-mediated apoptosis, including caspase-3 activation, degradation of poly(adp-ribose) polymerase (parp), loss of mitochondrial membrane potential (delta psim), and release of cytochrome c. however, subsequent (but not prior) exposure of paclitaxel-treated u937/bcl-xl cells (500 nm; 6 h) to bryostatin 1 (10 nm; 15 h) restored the extent of apoptosis, caspase activation, and mitochondrial damage to levels approximating those in paclitaxel-treated empty-vector control cells (u937/neo). |
1999-11-03 |
2023-08-12 |
human |
| B Joshi, L Li, B G Taffe, Z Zhu, S Wahl, H Tian, E Ben-Josef, J D Taylor, A T Porter, D G Tan. Apoptosis induction by a novel anti-prostate cancer compound, BMD188 (a fatty acid-containing hydroxamic acid), requires the mitochondrial respiratory chain. Cancer research. vol 59. issue 17. 1999-09-30. PMID:10485482. |
several lines of evidence indicate that bmd188-induced cell death depends on mrc: (a) the death could be significantly inhibited by several complex-specific respiration inhibitors; (b) respiration-deficient rho0 cells were more resistant than wild-type parent cells to apoptosis induction by bmd188; and (c) bmd188 induced a rapid increase in reactive oxygen species in mitochondria, an up-regulation of cytochrome c oxidase subunits, a biphasic alteration (i.e., an early hyperpolarization, followed by later hypopolarization) in the mitochondrial membrane potential (delta psi(m)), dramatic changes in mitochondrial morphology and distribution prior to caspase activation, and an abnormal proliferation of mitochondria at the ultrastructural level. |
1999-09-30 |
2023-08-12 |
Not clear |
| A S Dukhanin, D V Patrashev, S I Ogurtso. [Changes in the transmembrane potential of thymocytes during dexamethasone- and Ca2(+)-induced apoptosis]. Eksperimental'naia i klinicheskaia farmakologiia. vol 62. issue 3. 1999-09-20. PMID:10439947. |
by means of the method of potential-sensitive fluorescent probes is established that under dexametazone-induced apoptosis (0.1-10 microm) the reduction of transmembrane potentials (tmp, delta phi) on plasmatic (delta phi p) and mitochondrial (delta phi m) membranes of hormone-sensitive thymocytes is observed. |
1999-09-20 |
2023-08-12 |
rat |
| T Iida, H Ichimura, M Ui, T Shimada, W Akahata, T Igarashi, T Kuwata, E Ido, S Yonehara, J Imanishi, M Hayam. Sequential analysis of apoptosis induction in peripheral blood mononuclear cells and lymph nodes in the early phase of pathogenic and nonpathogenic SIVmac infection. AIDS research and human retroviruses. vol 15. issue 8. 1999-09-16. PMID:10357468. |
in macaques infected with a nonpathogenic derivative of sivmac239, sivmac delta nef, apoptosis of lymphocytes was induced as it was in sivmac239-infected macaques, but to a lesser degree, suggesting a correlation between the extent of apoptosis induction in lymphocytes in the early phase of sivmac infection and the pathogenicity of sivmac. |
1999-09-16 |
2023-08-12 |
Not clear |