| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lin Hu, Jiarui Wei, Yue Zhang, Ziyuan Wang, Junming Tang, Jian Tang, Yujiu Gao, Xiaoqiao Zhang, Yifan Li, Yantong Liu, Shinan Ma, Xingrong Guo, Qiufang Zhan. ANGPTL8 is a negative regulator in pathological cardiac hypertrophy. Cell death & disease. vol 13. issue 7. 2022-07-19. PMID:35851270. |
furthermore, the secretion of angptl8 from the liver was increased during hypertrophic processes, which were triggered by ang ii. |
2022-07-19 |
2023-08-14 |
mouse |
| Lin Hu, Jiarui Wei, Yue Zhang, Ziyuan Wang, Junming Tang, Jian Tang, Yujiu Gao, Xiaoqiao Zhang, Yifan Li, Yantong Liu, Shinan Ma, Xingrong Guo, Qiufang Zhan. ANGPTL8 is a negative regulator in pathological cardiac hypertrophy. Cell death & disease. vol 13. issue 7. 2022-07-19. PMID:35851270. |
in the ang ii- and transverse aortic constriction (tac)-induced mouse cardiac hypertrophy model, angptl8 deficiency remarkably accelerated cardiac hypertrophy and fibrosis with deteriorating cardiac dysfunction. |
2022-07-19 |
2023-08-14 |
mouse |
| Shuhan Bu, Hien C Nguyen, David C R Michels, Berk Rasheed, Sepideh Nikfarjam, Rohan Singh, Lynn Wang, Darshil A Patel, Shweta Singh, Mohammad Qadura, Krishna K Sing. Transcriptomics of angiotensin II-induced long noncoding and coding RNAs in endothelial cells. Journal of hypertension. vol 40. issue 7. 2022-06-28. PMID:35762471. |
angiotensin ii (ang ii)-induced endothelial dysfunction plays an important role in the pathogenesis of cardiovascular diseases such as systemic hypertension, cardiac hypertrophy and atherosclerosis. |
2022-06-28 |
2023-08-14 |
Not clear |
| Qiang Liu, Chenjun Han, Xiaoyun Wu, Jian Zhou, Wangfu Zan. F-box and WD repeat-containing protein 7 ameliorates angiotensin II-induced myocardial hypertrophic injury via the mTOR-mediated autophagy pathway. Experimental and therapeutic medicine. vol 24. issue 1. 2022-06-24. PMID:35747152. |
the present study attempted to explore the role of fbw7 in ang ii-induced myocardial hypertrophic injury and its associated mechanism of action. |
2022-06-24 |
2023-08-14 |
Not clear |
| Qiang Liu, Chenjun Han, Xiaoyun Wu, Jian Zhou, Wangfu Zan. F-box and WD repeat-containing protein 7 ameliorates angiotensin II-induced myocardial hypertrophic injury via the mTOR-mediated autophagy pathway. Experimental and therapeutic medicine. vol 24. issue 1. 2022-06-24. PMID:35747152. |
fbw7 overexpression promoted the cell viability, inhibited ang ii-induced apoptosis, cellular hypertrophy and fibrosis in h9c2 cells via the autophagic pathway, as well as inflammation and oxidative stress. |
2022-06-24 |
2023-08-14 |
Not clear |
| Qiang Liu, Chenjun Han, Xiaoyun Wu, Jian Zhou, Wangfu Zan. F-box and WD repeat-containing protein 7 ameliorates angiotensin II-induced myocardial hypertrophic injury via the mTOR-mediated autophagy pathway. Experimental and therapeutic medicine. vol 24. issue 1. 2022-06-24. PMID:35747152. |
overall, the data indicated that fbw7 overexpression ameliorated ang ii-induced hypertrophic myocardial injury via the mtor-mediated autophagic pathway. |
2022-06-24 |
2023-08-14 |
Not clear |
| Feng Chen, Wenfeng Li, Dandan Zhang, Youlin Fu, Wenjin Yuan, Gang Luo, Fuwei Liu, Jun Lu. MALAT1 regulates hypertrophy of cardiomyocytes by modulating the miR-181a/HMGB2 pathway. European journal of histochemistry : EJH. vol 66. issue 3. 2022-06-21. PMID:35726535. |
in the present study, we treated primary cardiomyocytes with angiotensin ii (ang ii) to mimic cardiac hypertrophy. |
2022-06-21 |
2023-08-14 |
Not clear |
| Feng Chen, Wenfeng Li, Dandan Zhang, Youlin Fu, Wenjin Yuan, Gang Luo, Fuwei Liu, Jun Lu. MALAT1 regulates hypertrophy of cardiomyocytes by modulating the miR-181a/HMGB2 pathway. European journal of histochemistry : EJH. vol 66. issue 3. 2022-06-21. PMID:35726535. |
ang ii-induced cardiac hypertrophy was suppressed by overexpression of malat1 and promoted by genetic knockdown of malat1. |
2022-06-21 |
2023-08-14 |
Not clear |
| Cansheng Zhu, Min Wang, Xianguan Yu, Xing Shui, Leile Tang, Zefeng Chen, Zhaojun Xion. lncRNA NBR2 attenuates angiotensin II-induced myocardial hypertrophy through repressing ER stress via activating LKB1/AMPK/Sirt1 pathway. Bioengineered. vol 13. issue 5. 2022-06-15. PMID:35703318. |
here, we explored the role and mechanism of a novel lncrna, nbr2, in modulating angiotensin ii (ang ii)-induced myocardial hypertrophy. |
2022-06-15 |
2023-08-14 |
human |
| Cansheng Zhu, Min Wang, Xianguan Yu, Xing Shui, Leile Tang, Zefeng Chen, Zhaojun Xion. lncRNA NBR2 attenuates angiotensin II-induced myocardial hypertrophy through repressing ER stress via activating LKB1/AMPK/Sirt1 pathway. Bioengineered. vol 13. issue 5. 2022-06-15. PMID:35703318. |
besides, ang ii treatment intensified the hypertrophy of human myocardial cell lines (hcm and ac16) and curbed the nbr2 expression. |
2022-06-15 |
2023-08-14 |
human |
| Yang Zhang, Yicong Ye, Xiaoqiang Tang, Hui Wang, Toshiko Tanaka, Ran Tian, Xufei Yang, Lun Wang, Ying Xiao, Xiaomin Hu, Ye Jin, Haiyu Pang, Tian Du, Honghong Liu, Lihong Sun, Shuo Xiao, Ruijia Dong, Luigi Ferrucci, Zhuang Tian, Shuyang Zhan. CCL17 acts as a novel therapeutic target in pathological cardiac hypertrophy and heart failure. The Journal of experimental medicine. vol 219. issue 8. 2022-06-10. PMID:35687056. |
subsequent animal experiments further revealed that ccll7-ko significantly repressed aging and angiotensin ii (ang ii)-induced cardiac hypertrophy and fibrosis, accompanied by the plasticity and differentiation of t cell subsets. |
2022-06-10 |
2023-08-14 |
Not clear |
| Yang Zhang, Yicong Ye, Xiaoqiang Tang, Hui Wang, Toshiko Tanaka, Ran Tian, Xufei Yang, Lun Wang, Ying Xiao, Xiaomin Hu, Ye Jin, Haiyu Pang, Tian Du, Honghong Liu, Lihong Sun, Shuo Xiao, Ruijia Dong, Luigi Ferrucci, Zhuang Tian, Shuyang Zhan. CCL17 acts as a novel therapeutic target in pathological cardiac hypertrophy and heart failure. The Journal of experimental medicine. vol 219. issue 8. 2022-06-10. PMID:35687056. |
our findings reveal that chemokine ccl17 is identifiable as a novel therapeutic target in age-related and ang ii-induced pathological cardiac hypertrophy and heart failure. |
2022-06-10 |
2023-08-14 |
Not clear |
| Rukhsana Gul, Nouf Alsalman, Assim A Alfadd. Inhibition of eNOS Partially Blunts the Beneficial Effects of Nebivolol on Angiotensin II-Induced Signaling in H9c2 Cardiomyoblasts. Current issues in molecular biology. vol 44. issue 5. 2022-06-09. PMID:35678673. |
in contrast, the nebivolol-induced reduction in the ang ii-triggered mtorc1 pathway and the mrna levels of hypertrophic markers anp, bnp, and β-mhc were not reversed with the addition of l-name to nebivolol. |
2022-06-09 |
2023-08-14 |
Not clear |
| Kadiam C Venkata Subbaiah, Jiangbin Wu, Wai Hong Wilson Tang, Peng Ya. FAM114A1 influences cardiac pathological remodeling by regulating angiotensin II signaling. JCI insight. 2022-06-07. PMID:35671117. |
homozygous knockout of fam114a1 (fam114a1-/-) in the mouse genome reduces cardiac hypertrophy and fibrosis while significantly restores cardiac function in angiotensin (ang) ii- and mi-induced hf mouse models. |
2022-06-07 |
2023-08-14 |
mouse |
| Acacia White, Rohan U Parekh, Srinivas Sriramul. Kininase I Inhibition Prevents Angiotensin II-Induced Hypertension and Target Organ Damage. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554203. |
blood pressure was measured using radio telemetry probes and hypertrophy was assessed in the heart and kidney after 14 days of ang ii-infusion, using weight/tibial length. |
2022-05-13 |
2023-08-13 |
mouse |
| Acacia White, Rohan U Parekh, Srinivas Sriramul. Kininase I Inhibition Prevents Angiotensin II-Induced Hypertension and Target Organ Damage. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554203. |
in addition, ang ii-infusion also induced significant cardiac (heart weight/tibia length: 8.5 +0.9 vs. 6.8 +0.6 mg/mm) and renal (kidney weight/tibia length: 11.8 +1.5 vs. 8.7 +0.9 mg/mm) hypertrophy in wt mice compared to vehicle treated mice. |
2022-05-13 |
2023-08-13 |
mouse |
| Acacia White, Rohan U Parekh, Srinivas Sriramul. Kininase I Inhibition Prevents Angiotensin II-Induced Hypertension and Target Organ Damage. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554203. |
however, cpnko mice exhibited an attenuation in cardiac and renal hypertrophy following ang ii administration. |
2022-05-13 |
2023-08-13 |
mouse |
| Keisuke Okuno, Keiichi Torimoto, Ryohei Kuroda, Stephanie Cicalese, Yoshiharu Okuno, Ryohei Kono, Shinsuke Marumoto, Hirotoshi Utsunomiya, Satoru Eguch. Fruit-juice Concentrate of Asian Plum Attenuates Vascular Remodeling Associated with Hypertension. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35557202. |
aortic medial hypertrophy was observed in control mice (n=5) after 2 weeks of ang ii infusion, which was attenuated in bew group (96 µm vs. 71 µm, respectively, p<0.01). |
2022-05-13 |
2023-08-13 |
mouse |
| Keisuke Okuno, Keiichi Torimoto, Stephanie Cicalese, Matthew Sparks, Satoru Eguch. Smooth Muscle At1a Receptor Mediates Perivascular Fibrosis in Angiotensin II-infused Mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35560912. |
angiotensin ii (ang ii) signaling via at1 receptor has been shown to play a critical role in the pathogenesis of hypertension, cardiovascular hypertrophy and fibrosis. |
2022-05-13 |
2023-08-13 |
mouse |
| Keisuke Okuno, Keiichi Torimoto, Stephanie Cicalese, Matthew Sparks, Satoru Eguch. Smooth Muscle At1a Receptor Mediates Perivascular Fibrosis in Angiotensin II-infused Mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35560912. |
we have demonstrated that adam17 expressed in vascular smooth muscle cells (vsmc) mediates egf receptor activation and promotes cardiac hypertrophy and perivascular fibrosis induced by ang ii. |
2022-05-13 |
2023-08-13 |
mouse |