| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Ohkubo, H Matsubara, Y Nozawa, Y Mori, S Murasawa, K Kijima, K Maruyama, H Masaki, Y Tsutumi, Y Shibazaki, T Iwasaka, M Inad. Angiotensin type 2 receptors are reexpressed by cardiac fibroblasts from failing myopathic hamster hearts and inhibit cell growth and fibrillar collagen metabolism. Circulation. vol 96. issue 11. 1998-01-06. PMID:9403620. |
angiotensin (ang) ii type 1 receptor (at1-r) induces cardiomyocyte hypertrophy and fibroblast proliferation, whereas the physiological role of at2-r in cardiac remodeling remains poorly defined. |
1998-01-06 |
2023-08-12 |
Not clear |
| M Obayashi, M Yano, M Kohno, S Kobayashi, T Tanigawa, K Hironaka, T Ryouke, M Matsuzak. Dose-dependent effect of ANG II-receptor antagonist on myocyte remodeling in rat cardiac hypertrophy. The American journal of physiology. vol 273. issue 4. 1997-12-10. PMID:9362249. |
dose-dependent effect of ang ii-receptor antagonist on myocyte remodeling in rat cardiac hypertrophy. |
1997-12-10 |
2023-08-12 |
rat |
| J Fareh, R M Touyz, E L Schiffrin, G Thibaul. Cardiac type-1 angiotensin II receptor status in deoxycorticosterone acetate-salt hypertension in rats. Hypertension (Dallas, Tex. : 1979). vol 30. issue 5. 1997-12-10. PMID:9369284. |
these findings report for the first time the cardiac cell-specific implication of ang ii and the intracellular calcium signaling pathway stimulated by the at1 receptor in cardiac hypertrophy in doca-salt-hypertensive rats. |
1997-12-10 |
2023-08-12 |
rat |
| M E Ullian, J R Raymond, M C Willingham, R V Pau. Regulation of vascular angiotensin II receptors by EGF. The American journal of physiology. vol 273. issue 4. 1997-11-21. PMID:9357768. |
after vascular endothelial injury, angiotensin ii (ang ii) plays a role in the resulting hypertrophic response, and expression of epidermal growth factor (egf) is enhanced. |
1997-11-21 |
2023-08-12 |
Not clear |
| G Wolf, F N Ziyade. Renal tubular hypertrophy induced by angiotensin II. Seminars in nephrology. vol 17. issue 5. 1997-11-18. PMID:9316213. |
angiotensin ii (ang ii) is a prime agent that has been linked to the progression of renal disease by a host of mechanisms, including the induction of tubular epithelial hypertrophy and stimulation of extracellular matrix biosynthesis. |
1997-11-18 |
2023-08-12 |
Not clear |
| G Wolf, F N Ziyade. Renal tubular hypertrophy induced by angiotensin II. Seminars in nephrology. vol 17. issue 5. 1997-11-18. PMID:9316213. |
epithelial cells exhibit distinct patterns of growth behavior after stimulation with ang ii (namely, hypertrophy of proximal tubule segments and proliferation of more distal segments). |
1997-11-18 |
2023-08-12 |
Not clear |
| G Wolf, F N Ziyade. Renal tubular hypertrophy induced by angiotensin II. Seminars in nephrology. vol 17. issue 5. 1997-11-18. PMID:9316213. |
the hypertrophic action of ang ii is mediated through high-affinity at1-receptors, involves activation of pertussis-toxin sensitive g1 proteins, and depends on a decrease in intracellular camp. |
1997-11-18 |
2023-08-12 |
Not clear |
| G Wolf, F N Ziyade. Renal tubular hypertrophy induced by angiotensin II. Seminars in nephrology. vol 17. issue 5. 1997-11-18. PMID:9316213. |
there is also compelling evidence that the ang ii-induced epithelial hypertrophy and the stimulated-synthesis of collagen type iv are mediated by increased transcription and production of tgf-beta. |
1997-11-18 |
2023-08-12 |
Not clear |
| G Wolf, F N Ziyade. Renal tubular hypertrophy induced by angiotensin II. Seminars in nephrology. vol 17. issue 5. 1997-11-18. PMID:9316213. |
the hypertrophic response to ang ii is greater in medium with high glucose concentration. |
1997-11-18 |
2023-08-12 |
Not clear |
| G Wolf, F N Ziyade. Renal tubular hypertrophy induced by angiotensin II. Seminars in nephrology. vol 17. issue 5. 1997-11-18. PMID:9316213. |
blockade of the action of ang ii prevents the renal hypertrophy and the tubulointerstitial fibrosis in animal models of chronic renal diseases (independent of changes in systemic or glomerular hemodynamics), in part through interception of ang ii-mediated induction of tgf-beta expression. |
1997-11-18 |
2023-08-12 |
Not clear |
| Y E Eskildsen-Helmond, K Bezstarosti, D H Dekkers, H A van Heugten, J M Lamer. Cross-talk between receptor-mediated phospholipase C-beta and D via protein kinase C as intracellular signal possibly leading to hypertrophy in serum-free cultured cardiomyocytes. Journal of molecular and cellular cardiology. vol 29. issue 9. 1997-10-23. PMID:9299377. |
phospholipase c-beta (plc-beta) signalling via protein kinase c (pkc) has been recognized as a major route by which stimuli such as alpha1-adrenergic agonists, endothelin-1 (et-1) and angiotensin ii (ang ii) induce hypertrophy of myocytes. |
1997-10-23 |
2023-08-12 |
rat |
| W Lear, M Ruzicka, F H Leene. ACE inhibitors and cardiac ACE mRNA in volume overload-induced cardiac hypertrophy. The American journal of physiology. vol 273. issue 2 Pt 2. 1997-09-25. PMID:9277479. |
quinapril, an angiotensin-converting enzyme (ace) inhibitor with high affinity for cardiac ace, prevents increases in both plasma and cardiac angiotensin ii (ang ii) and development of cardiac hypertrophy after aortocaval shunt in rats. |
1997-09-25 |
2023-08-12 |
rat |
| W Lear, M Ruzicka, F H Leene. ACE inhibitors and cardiac ACE mRNA in volume overload-induced cardiac hypertrophy. The American journal of physiology. vol 273. issue 2 Pt 2. 1997-09-25. PMID:9277479. |
this difference is more pronounced in volume overload-induced cardiac hypertrophy, presumably reflecting their different effects on cardiac ang ii. |
1997-09-25 |
2023-08-12 |
rat |
| L J Dell'italia, E Balcells, Q C Meng, X Su, D Schultz, S P Bishop, N Machida, I M Straeter-Knowlen, G H Hankes, R Dillon, R E Cartee, S Opari. Volume-overload cardiac hypertrophy is unaffected by ACE inhibitor treatment in dogs. The American journal of physiology. vol 273. issue 2 Pt 2. 1997-09-25. PMID:9277516. |
thus upregulation of the at1 receptor in the r-mr hearts may provide a mechanism by which normal intracardiac ang ii levels could continue to mediate lv hypertrophy. |
1997-09-25 |
2023-08-12 |
Not clear |
| H Sasamura, Y Nakazato, T Hayashida, Y Kitamura, M Hayashi, T Sarut. Regulation of vascular type 1 angiotensin receptors by cytokines. Hypertension (Dallas, Tex. : 1979). vol 30. issue 1 Pt 1. 1997-08-08. PMID:9231818. |
these results demonstrate that interleukin-1 alpha upregulates at1 receptors and enhances ang ii-stimulated hypertrophic responses. |
1997-08-08 |
2023-08-12 |
rat |
| T Takahashi, Y Kawahara, M Okuda, H Ueno, A Takeshita, M Yokoyam. Angiotensin II stimulates mitogen-activated protein kinases and protein synthesis by a Ras-independent pathway in vascular smooth muscle cells. The Journal of biological chemistry. vol 272. issue 25. 1997-07-21. PMID:9188505. |
angiotensin ii (ang ii), a potent hypertrophic factor of vascular smooth muscle cells (vsmc), induces activation of the ras protooncogene product (ras) and mitogen-activated protein (map) kinases and subsequent stimulation of protein synthesis in vsmc. |
1997-07-21 |
2023-08-12 |
rat |
| A M Duncan, L M Burrell, A Kladis, D J Campbel. Angiotensin and bradykinin peptides in rats with myocardial infarction. Journal of cardiac failure. vol 3. issue 1. 1997-07-02. PMID:9110254. |
angiotensin ii (ang ii) stimulates cardiac hypertrophy and fibrosis, whereas bradykinin [bk-(1-9)] has cardioprotective actions and reduces infarct size following myocardial infarction. |
1997-07-02 |
2023-08-12 |
rat |
| J P Valentin, L A Sechi, C A Griffin, M H Humphreys, M Schambela. The renin-angiotensin system and compensatory renal hypertrophy in the rat. American journal of hypertension. vol 10. issue 4 Pt 1. 1997-07-01. PMID:9128205. |
these data do not support a critical role for ang ii in compensatory renal hypertrophy. |
1997-07-01 |
2023-08-12 |
rat |
| A Sabri, B I Levy, P Poitevin, L Caputo, E Faggin, F Marotte, L Rappaport, J L Samue. Differential roles of AT1 and AT2 receptor subtypes in vascular trophic and phenotypic changes in response to stimulation with angiotensin II. Arteriosclerosis, thrombosis, and vascular biology. vol 17. issue 2. 1997-04-03. PMID:9081679. |
the aim of this study was to investigate the roles of angiotensin ii (ang ii) receptor subtypes 1 (at1) and 2 (at2) in producing vascular wall hypertrophy and qualitative changes in smooth muscle cell gene expression. |
1997-04-03 |
2023-08-12 |
rat |
| A Sabri, B I Levy, P Poitevin, L Caputo, E Faggin, F Marotte, L Rappaport, J L Samue. Differential roles of AT1 and AT2 receptor subtypes in vascular trophic and phenotypic changes in response to stimulation with angiotensin II. Arteriosclerosis, thrombosis, and vascular biology. vol 17. issue 2. 1997-04-03. PMID:9081679. |
ang ii-induced hypertension was associated with the development of medial hypertrophy of the aorta and coronary arteries accompanied by reversion of vascular smooth muscle cells (vsmcs) toward an immature phenotype, as shown by the expression of cellular fibronectin and nonmuscle myosin. |
1997-04-03 |
2023-08-12 |
rat |