| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S A Richardson, Y Tizab. Hyperactivity in the offspring of nicotine-treated rats: role of the mesolimbic and nigrostriatal dopaminergic pathways. Pharmacology, biochemistry, and behavior. vol 47. issue 2. 1994-05-02. PMID:8146225. |
discrete brain areas (the nucleus accumbens [nacc], striatum [str], frontal cortex [fc], ventral tegmental area [vta], and substantia nigra [sn]) were microdissected for the evaluation of dopamine (da) concentration and/or the d2 receptor subtype. |
1994-05-02 |
2023-08-12 |
rat |
| N Todo, T Momiyama, T Amano, Y Kohno, M Sas. Excitation by talipexole, a dopamine D2 agonist, of caudate nucleus neurons activated by nigral stimulation. Life sciences. vol 54. issue 14. 1994-04-26. PMID:7908115. |
an electrophysiological study using cats anesthetized with alpha-chloralose was performed to elucidate whether or not talipexole (b-ht 920 cl2: 6-allyl-2-amino -5, 6, 7, 8-tetrahydro-4h-thiazolo [4, 5 -d] -azepine-dihydrochroride), a dopamine d2 agonist, acts on postsynaptic dopamine receptors in the caudate nucleus (cn) neurons receiving excitatory input from the pars compacta of substantia nigra (sn). |
1994-04-26 |
2023-08-12 |
Not clear |
| O Stork, T Hashimoto, K Obat. Haloperidol activates tyrosine hydroxylase gene-expression in the rat substantia nigra, pars reticulata. Brain research. vol 633. issue 1-2. 1994-04-25. PMID:7907932. |
the cellular distribution of tyrosine hydroxylase (th) and th mrna in the rat substantia nigra (sn) was investigated using immunohistochemistry (imhc) and non-radioactive in situ hybridization histochemistry (ish), respectively. |
1994-04-25 |
2023-08-12 |
rat |
| N Garcia-Cairasco, V C Terra, M C Dorett. Midbrain substrates of audiogenic seizures in rats. Behavioural brain research. vol 58. issue 1-2. 1994-04-25. PMID:8136050. |
based upon selective lesion and microinjection (gaba, clobazam, nmda) studies of substantia nigra (sn), inferior colliculus (ic), superior colliculus (sc), and on specific knife cuts at midcollicular levels, we have suggested differential roles for these substrates in the origin and spreading of as. |
1994-04-25 |
2023-08-12 |
rat |
| G Chadi, A Møller, L Rosén, A M Janson, L A Agnati, M Goldstein, S O Ogren, R F Pettersson, K Fux. Protective actions of human recombinant basic fibroblast growth factor on MPTP-lesioned nigrostriatal dopamine neurons after intraventricular infusion. Experimental brain research. vol 97. issue 1. 1994-04-15. PMID:7907549. |
the hrfgf-2 produced an astroglial reaction as determined in the lateral neostriatum and in the substantia nigra (sn) far from the site of the infusion, indicating that the growth factor may have reached these regions by diffusion to activate the astroglia. |
1994-04-15 |
2023-08-12 |
human |
| S M Pellegrino, J M Woods, M J Drus. Effects of chronic ethanol consumption on G proteins in brain areas associated with the nigrostriatal and mesolimbic dopamine systems. Alcoholism, clinical and experimental research. vol 17. issue 6. 1994-03-31. PMID:8116839. |
the brain areas examined include the substantia nigra (sn), striatum (st), globus pallidus (gp), frontal cortex (fcx), nucleus accumbens (na), ventral tegmental area (vta), and ventral pallidum (vp). |
1994-03-31 |
2023-08-12 |
rat |
| C Garcia, P Schmitt, P D'Aléo, J Bittel, M Curé, J F Pujo. Regional specificity of the long-term variation of tyrosine hydroxylase protein in rat catecholaminergic cell groups after chronic heat exposure. Journal of neurochemistry. vol 62. issue 3. 1994-03-28. PMID:7906716. |
the present study was carried out to investigate the effect of chronic heat exposure on tyrosine hydroxylase (th) protein content in catecholaminergic rat brain-stem areas such as the anterior (lca) and posterior (lcp) locus coeruleus, the substantia nigra (sn), the ventral tegmental area, and the dorsomedial (dmm) and the ventrolateral medulla and in the adrenal gland (ag). |
1994-03-28 |
2023-08-12 |
rat |
| G Engberg, H Nissbrand. gamma-Hydroxybutyric acid (GHBA) induces pacemaker activity and inhibition of substantia nigra dopamine neurons by activating GABAB-receptors. Naunyn-Schmiedeberg's archives of pharmacology. vol 348. issue 5. 1994-03-28. PMID:8114948. |
in the present study the actions of gamma-hydroxybutyric acid (ghba) on dopaminergic neurons in the rat substantia nigra (sn) were pharmacologically analysed utilising extracellular single unit recording techniques. |
1994-03-28 |
2023-08-12 |
rat |
| B Hontanilla, S de las Heras, J M Giménez-Amay. Organization of the striatal projections from the rostral caudate nucleus to the globus pallidus, the entopeduncular nucleus, and the pars reticulata of the substantia nigra in the cat. The Anatomical record. vol 238. issue 1. 1994-03-25. PMID:7509579. |
after the injections, a detailed analysis of the terminal labeling was carried out within the globus pallidus (gp), the entopeduncular nucleus (ep), and the substantia nigra (sn) pars reticulata (snr). |
1994-03-25 |
2023-08-12 |
cat |
| R Wolf, U Tschern. Valproate effect on gamma-aminobutyric acid release in pars reticulata of substantia nigra: combination of push-pull perfusion and fluorescence histochemistry. Epilepsia. vol 35. issue 1. 1994-03-25. PMID:8112252. |
to study further the previously demonstrated suppressive in vivo effect of sodium valproate (vpa) on gamma-aminobutyric acid (gaba) release in the preoptic area, we examined gaba neurotransmission in substantia nigra (sn), using the push-pull cannula technique in freely moving ovariectomized rats. |
1994-03-25 |
2023-08-12 |
rat |
| H D Mosier, F M Crinella, J Yu, F C Culler, R A Janson. Food efficiency in rats following brain lesions which affect target body size: implications on the set point for target size. Growth, development, and aging : GDA. vol 57. issue 4. 1994-03-07. PMID:8300276. |
food efficiency for body weight gain and for metabolic size (the 0.75 power of body weight) was determined in rats that were experimentally stunted by neonatal head-irradiation or by bilateral electrolytic lesions produced soon after weaning in the dorsomedial hypothalamic nuclei (dmh) or the substantia nigra (sn). |
1994-03-07 |
2023-08-12 |
rat |
| M B Youdim, P Riedere. The role of iron in senescence of dopaminergic neurons in Parkinson's disease. Journal of neural transmission. Supplementum. vol 40. 1994-03-03. PMID:8294901. |
in parkinson's disease (pd) an elevation of iron with staging of the disease has been observed in the substantia nigra (sn), especially the zona compacta (zc). |
1994-03-03 |
2023-08-12 |
rat |
| S Morgan, G Nomikos, J P Husto. Behavioral analysis of asymmetries induced by unilateral 6-OHDA injections into the substantia nigra. Behavioral and neural biology. vol 60. issue 3. 1994-03-03. PMID:8297320. |
the intent of this study was to perform a detailed analysis of behavioral asymmetries (turning behavior) exhibited by animals which had sustained a unilateral lesion of the substantia nigra (sn). |
1994-03-03 |
2023-08-12 |
rat |
| D G Schaar, B A Sieber, C F Dreyfus, I B Blac. Regional and cell-specific expression of GDNF in rat brain. Experimental neurology. vol 124. issue 2. 1994-02-18. PMID:8287932. |
the survival of ventral mesencephalic substantia nigra (sn) dopamine neurons, which degenerate in parkinson's disease, is enhanced by glial cells in vitro. |
1994-02-18 |
2023-08-12 |
rat |
| G Engberg, T Kling-Petersen, H Nissbrand. GABAB-receptor activation alters the firing pattern of dopamine neurons in the rat substantia nigra. Synapse (New York, N.Y.). vol 15. issue 3. 1994-02-09. PMID:8278899. |
in the present study, extracellular recording techniques were used to investigate the significance of gabab-receptor activation for the firing properties of da neurons in the substantia nigra (sn) in the rat. |
1994-02-09 |
2023-08-12 |
rat |
| M T Herrero, E C Hirsch, A Kastner, M R Luquin, F Javoy-Agid, L M Gonzalo, J A Obeso, Y Agi. Neuromelanin accumulation with age in catecholaminergic neurons from Macaca fascicularis brainstem. Developmental neuroscience. vol 15. issue 1. 1994-01-28. PMID:7505739. |
the proportion of nm-containing cells among th-positive neurons varied from one catecholaminergic region to another: low in the hypothalamus and central gray substance (cgs); moderate in the cell group a8, and high in the ventral tegmental area (vta), locus coeruleus (lc) and substantia nigra (sn). |
1994-01-28 |
2023-08-12 |
monkey |
| S DiDonato, M Zeviani, P Giovannini, N Savarese, M Rimoldi, C Mariotti, F Girotti, T Caracen. Respiratory chain and mitochondrial DNA in muscle and brain in Parkinson's disease patients. Neurology. vol 43. issue 11. 1993-12-20. PMID:8232940. |
there are several reports of a defect of complex i in the substantia nigra (sn) of parkinson's disease (pd) patients. |
1993-12-20 |
2023-08-12 |
Not clear |
| F M Farin, C J Omiecinsk. Regiospecific expression of cytochrome P-450s and microsomal epoxide hydrolase in human brain tissue. Journal of toxicology and environmental health. vol 40. issue 2-3. 1993-12-13. PMID:7693960. |
relatively equivalent mrna expression levels of meh were detected in the cerebellum (c), frontal (f), occipital (o), pons (p), red nucleus (rn), and substantia nigra (sn) regions of brain. |
1993-12-13 |
2023-08-12 |
human |
| H Takashima, B R Walker, H E Cannon-Spoor, W J Free. Kainic acid lesions increase reafferentation of the striatum by substantia nigra grafts. Brain research. vol 621. issue 1. 1993-12-09. PMID:8221075. |
effects of kainic acid lesions of the striatum on reafferentation of the striatum produced by intraventricular substantia nigra (sn) grafts were investigated. |
1993-12-09 |
2023-08-12 |
rat |
| S N Yan. [Hypotensive effect of neuropeptide Y in substantia nigra]. Zhonghua xin xue guan bing za zhi. vol 21. issue 2. 1993-12-07. PMID:8223160. |
the central hypotensive effect of neuropeptide y (npy) has been investigated by microinjection of the peptide into substantia nigra (sn) of anesthetized normotensive rats. |
1993-12-07 |
2023-08-12 |
rat |