| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anna R Moore, Wen-Liang Zhou, Evgeniy S Potapenko, Eun-Ji Kim, Srdjan D Anti. Brief dopaminergic stimulations produce transient physiological changes in prefrontal pyramidal neurons. Brain research. vol 1370. 2011-11-23. PMID:21059342. |
in response to food reward and other pertinent events, midbrain dopaminergic neurons fire short bursts of action potentials causing a phasic release of dopamine in the prefrontal cortex (rapid and transient increases in cortical dopamine concentration). |
2011-11-23 |
2023-08-12 |
rat |
| Anna R Moore, Wen-Liang Zhou, Evgeniy S Potapenko, Eun-Ji Kim, Srdjan D Anti. Brief dopaminergic stimulations produce transient physiological changes in prefrontal pyramidal neurons. Brain research. vol 1370. 2011-11-23. PMID:21059342. |
our present data imply that one population of pfc pyramidal neurons receiving direct synaptic contacts from midbrain dopaminergic neurons would stall during the 0.5s of the phasic dopamine burst. |
2011-11-23 |
2023-08-12 |
rat |
| Katherine C M Chew, Eng-Tat Ang, Yee Kit Tai, Fai Tsang, Shun Qiang Lo, Elijah Ong, Wei-Yi Ong, Han-Ming Shen, Kah-Leong Lim, Valina L Dawson, Ted M Dawson, Tuck Wah Soon. Enhanced autophagy from chronic toxicity of iron and mutant A53T α-synuclein: implications for neuronal cell death in Parkinson disease. The Journal of biological chemistry. vol 286. issue 38. 2011-11-23. PMID:21795716. |
parkinson disease (pd), a prevalent neurodegenerative motor disorder, is characterized by the rather selective loss of dopaminergic neurons and the presence of α-synuclein-enriched lewy body inclusions in the substantia nigra of the midbrain. |
2011-11-23 |
2023-08-12 |
Not clear |
| Yoko Kameda, Takayoshi Saitoh, Takao Fujimur. Hes1 regulates the number and anterior-posterior patterning of mesencephalic dopaminergic neurons at the mid/hindbrain boundary (isthmus). Developmental biology. vol 358. issue 1. 2011-11-22. PMID:21798254. |
despite the severe defects of neurogenesis in null mutants, the mesencephalic dopaminergic (mesda) neurons were specified at the midline of the ventral mesencephalon in close proximity to two important signal centers - floor plate and mid/hindbrain boundary (i.e., the isthmic organizer). |
2011-11-22 |
2023-08-12 |
mouse |
| Tibor Koos, Fatuel Tecuapetla, James M Teppe. Glutamatergic signaling by midbrain dopaminergic neurons: recent insights from optogenetic, molecular and behavioral studies. Current opinion in neurobiology. vol 21. issue 3. 2011-11-21. PMID:21632236. |
glutamatergic signaling by midbrain dopaminergic neurons: recent insights from optogenetic, molecular and behavioral studies. |
2011-11-21 |
2023-08-12 |
Not clear |
| Retraction for Guo et al., Lmx1b-controlled isthmic organizer is essential for development of midbrain dopaminergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 39. 2011-11-21. PMID:21957266. |
retraction for guo et al., lmx1b-controlled isthmic organizer is essential for development of midbrain dopaminergic neurons. |
2011-11-21 |
2023-08-12 |
Not clear |
| Michael J Devine, Mina Ryten, Petr Vodicka, Alison J Thomson, Tom Burdon, Henry Houlden, Fatima Cavaleri, Masumi Nagano, Nicola J Drummond, Jan-Willem Taanman, Anthony H Schapira, Katrina Gwinn, John Hardy, Patrick A Lewis, Tilo Kunat. Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus. Nature communications. vol 2. 2011-11-18. PMID:21863007. |
when these cells are differentiated into midbrain dopaminergic neurons, those from the patient produce double the amount of α-synuclein protein as neurons from the unaffected relative, precisely recapitulating the cause of parkinson's disease in these individuals. |
2011-11-18 |
2023-08-12 |
Not clear |
| Michela Deleidi, Gunnar Hargus, Penelope Hallett, Teresia Osborn, Ole Isacso. Development of histocompatible primate-induced pluripotent stem cells for neural transplantation. Stem cells (Dayton, Ohio). vol 29. issue 7. 2011-11-15. PMID:21608081. |
we characterized the immunological properties of cm-ipscs and demonstrated that cm-ipscs can be induced to differentiate in vitro along specific neuronal populations, such as midbrain dopaminergic (da) neurons. |
2011-11-15 |
2023-08-12 |
human |
| Sandra Blaess, Gabriela O Bodea, Anna Kabanova, Soline Chanet, Emilie Mugniery, Amin Derouiche, Daniel Stephen, Alexandra L Joyne. Temporal-spatial changes in Sonic Hedgehog expression and signaling reveal different potentials of ventral mesencephalic progenitors to populate distinct ventral midbrain nuclei. Neural development. vol 6. 2011-11-15. PMID:21689430. |
the ventral midbrain contains a diverse array of neurons, including dopaminergic neurons of the ventral tegmental area (vta) and substantia nigra (sn) and neurons of the red nucleus (rn). |
2011-11-15 |
2023-08-12 |
Not clear |
| Daniel Alvarez-Fischer, Julia Fuchs, François Castagner, Olivier Stettler, Olivia Massiani-Beaudoin, Kenneth L Moya, Colette Bouillot, Wolfgang H Oertel, Anne Lombès, Wolfgang Faigle, Rajiv L Joshi, Andreas Hartmann, Alain Prochiant. Engrailed protects mouse midbrain dopaminergic neurons against mitochondrial complex I insults. Nature neuroscience. vol 14. issue 10. 2011-11-15. PMID:21892157. |
engrailed protects mouse midbrain dopaminergic neurons against mitochondrial complex i insults. |
2011-11-15 |
2023-08-12 |
mouse |
| Wendou Yu, Yaping Sun, Su Guo, Bingwei L. The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons. Human molecular genetics. vol 20. issue 16. 2011-11-10. PMID:21613270. |
finally, we found that pink1/parkin similarly influenced mitochondrial dynamics in rat midbrain dopaminergic neurons. |
2011-11-10 |
2023-08-12 |
rat |
| Francesca L'episcopo, Maria F Serapide, Cataldo Tirolo, Nunzio Testa, Salvatore Caniglia, Maria C Morale, Stefano Pluchino, Bianca Marchett. A Wnt1 regulated Frizzled-1/β-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotection. Molecular neurodegeneration. vol 6. 2011-11-10. PMID:21752258. |
dopamine-synthesizing (dopaminergic, da) neurons in the ventral midbrain (vm) constitute a pivotal neuronal population controlling motor behaviors, cognitive and affective brain functions, which generation critically relies on the activation of wingless-type mmtv integration site (wnt)/β-catenin pathway in their progenitors. |
2011-11-10 |
2023-08-12 |
mouse |
| Alessandra Bonito-Oliva, Michael Feyder, Gilberto Fison. Deciphering the Actions of Antiparkinsonian and Antipsychotic Drugs on cAMP/DARPP-32 Signaling. Frontiers in neuroanatomy. vol 5. 2011-11-10. PMID:21808606. |
msns receive a large glutamatergic innervation from cortex, thalamus, and limbic structures, and are controlled by dopaminergic projections originating in the midbrain. |
2011-11-10 |
2023-08-12 |
Not clear |
| Pierre F Durieux, Serge N Schiffmann, Alban de Kerchove d'Exaerd. Targeting neuronal populations of the striatum. Frontiers in neuroanatomy. vol 5. 2011-11-10. PMID:21811438. |
the gaba medium-sized spiny neurons (msns, about 95% of striatal neurons), which are targets of the cerebral cortex and the midbrain dopaminergic neurons, form two pathways. |
2011-11-10 |
2023-08-12 |
Not clear |
| Michael Fiske, Stephanie Valtierra, Keith Solvang, Michael Zorniak, Michael White, Sara Herrera, Alina Konnikova, Rebecca Brezinsky, Shubhik Debburma. Contribution of Alanine-76 and Serine Phosphorylation in α-Synuclein Membrane Association and Aggregation in Yeasts. Parkinson's disease. vol 2011. 2011-11-10. PMID:21826257. |
in parkinson's disease (pd), misfolded and aggregated α-synuclein protein accumulates in degenerating midbrain dopaminergic neurons. |
2011-11-10 |
2023-08-12 |
Not clear |
| Mario Gustavo Murer, Rosario Moratall. Striatal Signaling in L-DOPA-Induced Dyskinesia: Common Mechanisms with Drug Abuse and Long Term Memory Involving D1 Dopamine Receptor Stimulation. Frontiers in neuroanatomy. vol 5. 2011-11-10. PMID:21886608. |
parkinson's disease is a common neurodegenerative disorder caused by the degeneration of midbrain substantia nigra dopaminergic neurons that project to the striatum. |
2011-11-10 |
2023-08-12 |
Not clear |
| Christopher J Burke, Philippe N Toble. Coding of reward probability and risk by single neurons in animals. Frontiers in neuroscience. vol 5. 2011-11-10. PMID:22013410. |
reward variance is represented in orbitofrontal and posterior cingulate cortex and through a sustained response of dopaminergic midbrain neurons. |
2011-11-10 |
2023-08-12 |
rat |
| Timothy J Petros, Jennifer A Tyson, Stewart A Anderso. Pluripotent stem cells for the study of CNS development. Frontiers in molecular neuroscience. vol 4. 2011-11-10. PMID:22016722. |
additionally, we highlight the derivation of several thoroughly characterized neural subtypes; spinal motoneurons, midbrain dopaminergic neurons and cortical neurons. |
2011-11-10 |
2023-08-12 |
human |
| Andrii Domanskyi, Christin Geissler, Ilya A Vinnikov, Heike Alter, Andreas Schober, Miriam A Vogt, Peter Gass, Rosanna Parlato, Günther Schüt. Pten ablation in adult dopaminergic neurons is neuroprotective in Parkinson's disease models. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 25. issue 9. 2011-11-09. PMID:21593433. |
parkinson's disease (pd) is a progressive age-related movement disorder that results primarily from the selective loss of midbrain dopaminergic (da) neurons. |
2011-11-09 |
2023-08-12 |
mouse |
| Vishnu P Murty, Fabio Sambataro, Eugenia Radulescu, Mario Altamura, Jennifer Iudicello, Bradley Zoltick, Daniel R Weinberger, Terry E Goldberg, Venkata S Matta. Selective updating of working memory content modulates meso-cortico-striatal activity. NeuroImage. vol 57. issue 3. 2011-11-09. PMID:21596142. |
accumulating evidence from non-human primates and computational modeling suggests that dopaminergic signals arising from the midbrain (substantia nigra/ventral tegmental area) mediate striatal gating of the prefrontal cortex during the selective updating of working memory. |
2011-11-09 |
2023-08-12 |
human |