| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maria L Cucchiaroni, Peter S Freestone, Nicola Berretta, Maria T Viscomi, Elisa Bisicchia, Hideyuki Okano, Marco Molinari, Giorgio Bernardi, Janusz Lipski, Nicola B Mercuri, Ezia Guatte. Properties of dopaminergic neurons in organotypic mesencephalic-striatal co-cultures--evidence for a facilitatory effect of dopamine on the glutamatergic input mediated by α-1 adrenergic receptors. The European journal of neuroscience. vol 33. issue 9. 2011-09-16. PMID:21453288. |
organotypic cultures (ocs) have been widely used to investigate the midbrain dopaminergic system, but only a few studies focused on the functional properties of dopaminergic neurons and their synaptic inputs from dopaminergic and non-dopaminergic neurons also contained in such cultures. |
2011-09-16 |
2023-08-12 |
mouse |
| Maria L Cucchiaroni, Peter S Freestone, Nicola Berretta, Maria T Viscomi, Elisa Bisicchia, Hideyuki Okano, Marco Molinari, Giorgio Bernardi, Janusz Lipski, Nicola B Mercuri, Ezia Guatte. Properties of dopaminergic neurons in organotypic mesencephalic-striatal co-cultures--evidence for a facilitatory effect of dopamine on the glutamatergic input mediated by α-1 adrenergic receptors. The European journal of neuroscience. vol 33. issue 9. 2011-09-16. PMID:21453288. |
the facilitatory effect of da on glutamatergic transmission to midbrain dopaminergic neurons may be important in conditions when the expression of d₂ receptors is compromised, such as long-term treatment with antipsychotic drugs. |
2011-09-16 |
2023-08-12 |
mouse |
| Maria T M Alves dos Santos, Marten P Smid. En1 and Wnt signaling in midbrain dopaminergic neuronal development. Neural development. vol 6. 2011-09-13. PMID:21569278. |
en1 and wnt signaling in midbrain dopaminergic neuronal development. |
2011-09-13 |
2023-08-12 |
Not clear |
| Cindy Van Humbeeck, Tom Cornelissen, Hilde Hofkens, Wim Mandemakers, Kris Gevaert, Bart De Strooper, Wim Vandenbergh. Parkin interacts with Ambra1 to induce mitophagy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 28. 2011-09-12. PMID:21753002. |
we found ambra1, like parkin, to be widely expressed in adult mouse brain, including midbrain dopaminergic neurons. |
2011-09-12 |
2023-08-12 |
mouse |
| Wiebke Potjans, Markus Diesmann, Abigail Morriso. An imperfect dopaminergic error signal can drive temporal-difference learning. PLoS computational biology. vol 7. issue 5. 2011-09-09. PMID:21589888. |
experimental evidence that supports the hypothesis that the mammalian brain performs temporal-difference learning includes the resemblance of the phasic activity of the midbrain dopaminergic neurons to the td error and the discovery that cortico-striatal synaptic plasticity is modulated by dopamine. |
2011-09-09 |
2023-08-12 |
Not clear |
| Xiaoying Cui, Matthew Pelekanos, Thomas H J Burne, John J McGrath, Darryl W Eyle. Maternal vitamin D deficiency alters the expression of genes involved in dopamine specification in the developing rat mesencephalon. Neuroscience letters. vol 486. issue 3. 2011-09-06. PMID:20884326. |
the aim of this study was to examine the expression of genes important for dopaminergic development and maturation within the embryonic mesencephalon using an epidemiologically-informed animal model of schizophrenia, the developmental vitamin d (dvd) deficient rat model. |
2011-09-06 |
2023-08-12 |
rat |
| Sangmi Chung, Jung-Il Moon, Amanda Leung, Daniel Aldrich, Stefan Lukianov, Yui Kitayama, Sara Park, Yan Li, Vadim Y Bolshakov, Thomas Lamonerie, Kwang-Soo Ki. ES cell-derived renewable and functional midbrain dopaminergic progenitors. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 23. 2011-08-26. PMID:21606375. |
es cell-derived renewable and functional midbrain dopaminergic progenitors. |
2011-08-26 |
2023-08-12 |
mouse |
| Sangmi Chung, Jung-Il Moon, Amanda Leung, Daniel Aldrich, Stefan Lukianov, Yui Kitayama, Sara Park, Yan Li, Vadim Y Bolshakov, Thomas Lamonerie, Kwang-Soo Ki. ES cell-derived renewable and functional midbrain dopaminergic progenitors. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 23. 2011-08-26. PMID:21606375. |
during early development, midbrain dopaminergic (mda) neuronal progenitors (nps) arise from the ventral mesencephalic area by the combined actions of secreted factors and their downstream transcription factors. |
2011-08-26 |
2023-08-12 |
mouse |
| Gunasingh J Masilamoni, James W Bogenpohl, David Alagille, Kristen Delevich, Gilles Tamagnan, John R Votaw, Thomas Wichmann, Yoland Smit. Metabotropic glutamate receptor 5 antagonist protects dopaminergic and noradrenergic neurons from degeneration in MPTP-treated monkeys. Brain : a journal of neurology. vol 134. issue Pt 7. 2011-08-26. PMID:21705423. |
these behavioural observations were consistent with in vivo positron emission tomography dopamine transporter imaging data, and with post-mortem stereological counts of midbrain dopaminergic neurons, as well as striatal intensity measurements of dopamine transporter and tyrosine hydroxylase immunoreactivity, which were all significantly higher in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/3-[(2-methyl-1,3-thiazol-4-yl) ethynyl] pyridine-treated animals than in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/vehicle-treated monkeys. |
2011-08-26 |
2023-08-12 |
monkey |
| Rajeswara Babu Mythri, Jayagopalan Veena, G Harish, B S Shankaranarayana Rao, M M Srinivas Bharat. Chronic dietary supplementation with turmeric protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-mediated neurotoxicity in vivo: implications for Parkinson's disease. The British journal of nutrition. vol 106. issue 1. 2011-08-25. PMID:21473798. |
therefore, there is a demand for novel compound(s)/products that could target multiple pathways and protect the dying midbrain dopaminergic neurons, with potential utility as adjunctive therapy along with conventional drugs. |
2011-08-25 |
2023-08-12 |
mouse |
| Brette D Blakely, Christopher R Bye, Chathurini V Fernando, Malcolm K Horne, Maria L Macheda, Steven A Stacker, Ernest Arenas, Clare L Paris. Wnt5a regulates midbrain dopaminergic axon growth and guidance. PloS one. vol 6. issue 3. 2011-08-25. PMID:21483795. |
wnt5a regulates midbrain dopaminergic axon growth and guidance. |
2011-08-25 |
2023-08-12 |
mouse |
| Brette D Blakely, Christopher R Bye, Chathurini V Fernando, Malcolm K Horne, Maria L Macheda, Steven A Stacker, Ernest Arenas, Clare L Paris. Wnt5a regulates midbrain dopaminergic axon growth and guidance. PloS one. vol 6. issue 3. 2011-08-25. PMID:21483795. |
within the developing ventral midbrain (vm) the cues that guide dopaminergic (da) axons to their forebrain targets remain to be fully elucidated. |
2011-08-25 |
2023-08-12 |
mouse |
| Irina N Krasnova, Bruce Ladenheim, Amber B Hodges, Nora D Volkow, Jean Lud Cade. Chronic methamphetamine administration causes differential regulation of transcription factors in the rat midbrain. PloS one. vol 6. issue 4. 2011-08-25. PMID:21547080. |
when administered in large doses, meth can cause depletion of striatal dopamine terminals, with preservation of midbrain dopaminergic neurons. |
2011-08-25 |
2023-08-12 |
rat |
| Nicole Gennet, Emily Gale, Xinsheng Nan, Emma Farley, Katalin Takacs, Barbara Oberwallner, David Chambers, Meng L. Doublesex and mab-3-related transcription factor 5 promotes midbrain dopaminergic identity in pluripotent stem cells by enforcing a ventral-medial progenitor fate. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 22. 2011-08-23. PMID:21576465. |
doublesex and mab-3-related transcription factor 5 promotes midbrain dopaminergic identity in pluripotent stem cells by enforcing a ventral-medial progenitor fate. |
2011-08-23 |
2023-08-12 |
Not clear |
| S R L Stacpoole, B Bilican, D J Webber, A Luzhynskaya, X L He, A Compston, R Karadottir, R J M Franklin, S Chandra. Derivation of neural precursor cells from human ES cells at 3% O(2) is efficient, enhances survival and presents no barrier to regional specification and functional differentiation. Cell death and differentiation. vol 18. issue 6. 2011-08-22. PMID:21274009. |
we also show that npcs derived under 3% o(2) can be differentiated long term in the absence of neurotrophins and can be readily specified into both spinal motor neurons and midbrain dopaminergic neurons. |
2011-08-22 |
2023-08-12 |
human |
| M Eapen, D H Zald, J C Gatenby, Z Ding, J C Gor. Using high-resolution MR imaging at 7T to evaluate the anatomy of the midbrain dopaminergic system. AJNR. American journal of neuroradiology. vol 32. issue 4. 2011-08-17. PMID:21183619. |
using high-resolution mr imaging at 7t to evaluate the anatomy of the midbrain dopaminergic system. |
2011-08-17 |
2023-08-12 |
human |
| Jun Hu, Chenlei Zhu, Yuan Liu, Fang Wang, Zuhu Huang, Weimin Fan, Jie W. Dynamic alterations of gene expression of nicotinic acetylcholine receptor α7, α4 and β2 subunits in an acute MPTP-lesioned mouse model. Neuroscience letters. vol 494. issue 3. 2011-08-17. PMID:21406211. |
nicotine, a potent agonist of nicotinic acetylcholine receptors (nachrs), excites midbrain dopaminergic neurons and this may contribute to the anti-parkinsonian effects. |
2011-08-17 |
2023-08-12 |
mouse |
| Francisco J Gómez, Pabla Aguirre, Christian Gonzalez-Billault, Marco T Núñe. Iron mediates neuritic tree collapse in mesencephalic neurons treated with 1-methyl-4-phenylpyridinium (MPP+). Journal of neural transmission (Vienna, Austria : 1996). vol 118. issue 3. 2011-08-16. PMID:20890618. |
in this study, we characterized the effect of mpp+, an inhibitor of mitochondria complex i, on the integrity of the neuritic tree of midbrain dopaminergic neurons, and determined the influence of iron and cellular levels of gsh on this degeneration. |
2011-08-16 |
2023-08-12 |
mouse |
| Tuck C Ngun, Negar Ghahramani, Francisco J Sánchez, Sven Bocklandt, Eric Vilai. The genetics of sex differences in brain and behavior. Frontiers in neuroendocrinology. vol 32. issue 2. 2011-08-15. PMID:20951723. |
we highlight the 'four core genotypes' model and sex differences in the midbrain dopaminergic system, specifically focusing on the role of sry. |
2011-08-15 |
2023-08-12 |
Not clear |
| Yuriko Iwakura, Yingjun Zheng, Maria Sibilia, Yuichi Abe, Ying-Shan Piao, Daisaku Yokomaku, Ran Wang, Yuta Ishizuka, Nobuyuki Takei, Hiroyuki Naw. Qualitative and quantitative re-evaluation of epidermal growth factor-ErbB1 action on developing midbrain dopaminergic neurons in vivo and in vitro: target-derived neurotrophic signaling (Part 1). Journal of neurochemistry. vol 118. issue 1. 2011-08-12. PMID:21517852. |
qualitative and quantitative re-evaluation of epidermal growth factor-erbb1 action on developing midbrain dopaminergic neurons in vivo and in vitro: target-derived neurotrophic signaling (part 1). |
2011-08-12 |
2023-08-12 |
mouse |