Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Donna W Lee, Sarah A Notter, Mona Thiruchelvam, Daniel P Dever, Richard Fitzpatrick, Paul J Kostyniak, Deborah A Cory-Slechta, Lisa A Opanashu. Subchronic polychlorinated biphenyl (Aroclor 1254) exposure produces oxidative damage and neuronal death of ventral midbrain dopaminergic systems. Toxicological sciences : an official journal of the Society of Toxicology. vol 125. issue 2. 2012-05-17. PMID:22094459. |
subchronic polychlorinated biphenyl (aroclor 1254) exposure produces oxidative damage and neuronal death of ventral midbrain dopaminergic systems. |
2012-05-17 |
2023-08-12 |
Not clear |
Pablo Henny, Matthew T C Brown, Augustus Northrop, Macarena Faunes, Mark A Ungless, Peter J Magill, J Paul Bola. Structural correlates of heterogeneous in vivo activity of midbrain dopaminergic neurons. Nature neuroscience. vol 15. issue 4. 2012-05-16. PMID:22327472. |
structural correlates of heterogeneous in vivo activity of midbrain dopaminergic neurons. |
2012-05-16 |
2023-08-12 |
rat |
Pablo Henny, Matthew T C Brown, Augustus Northrop, Macarena Faunes, Mark A Ungless, Peter J Magill, J Paul Bola. Structural correlates of heterogeneous in vivo activity of midbrain dopaminergic neurons. Nature neuroscience. vol 15. issue 4. 2012-05-16. PMID:22327472. |
we conclude that diverse wiring patterns determine the heterogeneous activities of midbrain dopaminergic neurons in vivo. |
2012-05-16 |
2023-08-12 |
rat |
A Sánchez-Danés, A Consiglio, Y Richaud, I Rodríguez-Pizà, B Dehay, M Edel, J Bové, M Memo, M Vila, A Raya, J C Izpisua Belmont. Efficient generation of A9 midbrain dopaminergic neurons by lentiviral delivery of LMX1A in human embryonic stem cells and induced pluripotent stem cells. Human gene therapy. vol 23. issue 1. 2012-05-10. PMID:21877920. |
efficient generation of a9 midbrain dopaminergic neurons by lentiviral delivery of lmx1a in human embryonic stem cells and induced pluripotent stem cells. |
2012-05-10 |
2023-08-12 |
mouse |
Soyoung Q Park, Thorsten Kahnt, Deborah Talmi, Jörg Rieskamp, Raymond J Dolan, Hauke R Heekere. Adaptive coding of reward prediction errors is gated by striatal coupling. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 11. 2012-05-08. PMID:22371590. |
to efficiently represent all of the possible rewards in the world, dopaminergic midbrain neurons dynamically adapt their coding range to the momentarily available rewards. |
2012-05-08 |
2023-08-12 |
human |
Almas Siddiqui, Jyothi K Mallajosyula, Anand Rane, Julie K Anderse. Ability to delay neuropathological events associated with astrocytic MAO-B increase in a Parkinsonian mouse model: implications for early intervention on disease progression. Neurobiology of disease. vol 43. issue 2. 2012-05-07. PMID:21809503. |
we previously demonstrated that elevation of astrocytic monoamine oxidase b (mao-b) levels in adoxycycline (dox)-inducible transgenic mouse model following 14 days of dox induction results in several neuropathologic features similar to those observed in the parkinsonian midbrain (mallajosyula et al., 2008).these include a specific, selective and progressive loss of dopaminergic neurons of the substantia nigra (sn),selective decreases in mitochondrial complex i (ci) activity and increased oxidative stress. |
2012-05-07 |
2023-08-12 |
mouse |
Yanzhong Guan, Cheng Xiao, Kresimir Krnjevic, Guiqin Xie, Wanhong Zuo, Jiang-Hong Y. GABAergic actions mediate opposite ethanol effects on dopaminergic neurons in the anterior and posterior ventral tegmental area. The Journal of pharmacology and experimental therapeutics. vol 341. issue 1. 2012-05-04. PMID:22209891. |
in patch-clamp recordings in midbrain slices from young rats (postnatal days 22-32), we detected no significant difference in electrophysiological properties between p-vta and a-vta dopaminergic neurons. |
2012-05-04 |
2023-08-12 |
rat |
Shuyan Wang, Ping Ren, Xiaobo Li, Yunqian Guan, Yu Alex Zhan. 17β-estradiol protects dopaminergic neurons in organotypic slice of mesencephalon by MAPK-mediated activation of anti-apoptosis gene BCL2. Journal of molecular neuroscience : MN. vol 45. issue 2. 2012-04-24. PMID:21327582. |
17β-estradiol protects dopaminergic neurons in organotypic slice of mesencephalon by mapk-mediated activation of anti-apoptosis gene bcl2. |
2012-04-24 |
2023-08-12 |
Not clear |
Hassan Niknejad, Tina Deihim, Abolhassan Ahmadiani, Masoumeh Jorjani, Habibollah Peirov. Permanent expression of midbrain dopaminergic neurons traits in differentiated amniotic epithelial cells. Neuroscience letters. vol 506. issue 1. 2012-04-24. PMID:22037229. |
permanent expression of midbrain dopaminergic neurons traits in differentiated amniotic epithelial cells. |
2012-04-24 |
2023-08-12 |
human |
Hassan Niknejad, Tina Deihim, Abolhassan Ahmadiani, Masoumeh Jorjani, Habibollah Peirov. Permanent expression of midbrain dopaminergic neurons traits in differentiated amniotic epithelial cells. Neuroscience letters. vol 506. issue 1. 2012-04-24. PMID:22037229. |
aecs may differentiate into midbrain dopaminergic neurons in the presence of induction factors which trigger pathway naturally occurring in the mesencephalon during embryogenesis. |
2012-04-24 |
2023-08-12 |
human |
Hassan Niknejad, Tina Deihim, Abolhassan Ahmadiani, Masoumeh Jorjani, Habibollah Peirov. Permanent expression of midbrain dopaminergic neurons traits in differentiated amniotic epithelial cells. Neuroscience letters. vol 506. issue 1. 2012-04-24. PMID:22037229. |
in this study, we examined whether fgf8 and sonic hedgehog (shh) can induce aecs to express permanently midbrain dopaminergic neurons traits. |
2012-04-24 |
2023-08-12 |
human |
Russell C Addis, Fu-Chun Hsu, Rebecca L Wright, Marc A Dichter, Douglas A Coulter, John D Gearhar. Efficient conversion of astrocytes to functional midbrain dopaminergic neurons using a single polycistronic vector. PloS one. vol 6. issue 12. 2012-04-23. PMID:22174877. |
efficient conversion of astrocytes to functional midbrain dopaminergic neurons using a single polycistronic vector. |
2012-04-23 |
2023-08-12 |
Not clear |
Russell C Addis, Fu-Chun Hsu, Rebecca L Wright, Marc A Dichter, Douglas A Coulter, John D Gearhar. Efficient conversion of astrocytes to functional midbrain dopaminergic neurons using a single polycistronic vector. PloS one. vol 6. issue 12. 2012-04-23. PMID:22174877. |
in efforts to understand and treat parkinson's disease (pd), which is marked by the degeneration of dopaminergic neurons in the midbrain, direct reprogramming provides a valuable new source of these cells. |
2012-04-23 |
2023-08-12 |
Not clear |
Russell C Addis, Fu-Chun Hsu, Rebecca L Wright, Marc A Dichter, Douglas A Coulter, John D Gearhar. Efficient conversion of astrocytes to functional midbrain dopaminergic neurons using a single polycistronic vector. PloS one. vol 6. issue 12. 2012-04-23. PMID:22174877. |
the neurons exhibit expression profiles and electrophysiological characteristics consistent with midbrain dopaminergic neurons, notably including spontaneous pacemaking activity, stimulated release of dopamine, and calcium oscillations. |
2012-04-23 |
2023-08-12 |
Not clear |
Collin J Lobb, Charles J Wilson, Carlos A Paladin. High-frequency, short-latency disinhibition bursting of midbrain dopaminergic neurons. Journal of neurophysiology. vol 105. issue 5. 2012-04-17. PMID:21367999. |
high-frequency, short-latency disinhibition bursting of midbrain dopaminergic neurons. |
2012-04-17 |
2023-08-12 |
Not clear |
Billy Chieng, Yael Azriel, Sarasa Mohammadi, MacDonald J Christi. Distinct cellular properties of identified dopaminergic and GABAergic neurons in the mouse ventral tegmental area. The Journal of physiology. vol 589. issue Pt 15. 2012-04-17. PMID:21646409. |
the midbrain ventral tegmental area (vta) contains neurons largely with either a dopaminergic (daergic) or gabaergic phenotype. |
2012-04-17 |
2023-08-12 |
mouse |
A M Oster, B S Gutki. A reduced model of DA neuronal dynamics that displays quiescence, tonic firing and bursting. Journal of physiology, Paris. vol 105. issue 1-3. 2012-04-17. PMID:21939761. |
midbrain dopaminergic neurons send numerous projections to cortical and sub-cortical areas, and in a manner dependent upon their activities, diffusely release dopamine (da) to their targets. |
2012-04-17 |
2023-08-12 |
Not clear |
M Giorgi, G Melchiorri, V Nuccetelli, V D'Angelo, A Martorana, R Sorge, V Castelli, G Bernardi, G Sancesari. PDE10A and PDE10A-dependent cAMP catabolism are dysregulated oppositely in striatum and nucleus accumbens after lesion of midbrain dopamine neurons in rat: a key step in parkinsonism physiopathology. Neurobiology of disease. vol 43. issue 1. 2012-04-09. PMID:21515371. |
our objective was to examine whether expression of phosphodiesterase 10a (pde10a), an isozyme presenting a unique distribution in basal ganglia, is altered after unilateral injection of 6-hydroxydopamine in the medial forebrain bundle, eliminating all midbrain dopaminergic neurons, such that cyclic nucleotide catabolism and steady state could be affected. |
2012-04-09 |
2023-08-12 |
rat |
Jongpil Kim, Susan C Su, Haoyi Wang, Albert W Cheng, John P Cassady, Michael A Lodato, Christopher J Lengner, Chee-Yeun Chung, Meelad M Dawlaty, Li-Huei Tsai, Rudolf Jaenisc. Functional integration of dopaminergic neurons directly converted from mouse fibroblasts. Cell stem cell. vol 9. issue 5. 2012-04-09. PMID:22019014. |
here we show that ectopic expression of defined transcription factors in mouse tail tip fibroblasts is sufficient to induce pitx3+ neurons that closely resemble midbrain dopaminergic (da) neurons. |
2012-04-09 |
2023-08-12 |
mouse |
Diogo Ribeiro, Kristina Ellwanger, Désirée Glagow, Spyridon Theofilopoulos, Nina S Corsini, Ana Martin-Villalba, Christof Niehrs, Ernest Arena. Dkk1 regulates ventral midbrain dopaminergic differentiation and morphogenesis. PloS one. vol 6. issue 2. 2012-04-02. PMID:21347250. |
dkk1 regulates ventral midbrain dopaminergic differentiation and morphogenesis. |
2012-04-02 |
2023-08-12 |
mouse |