| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andrea Meixner, Karsten Boldt, Marleen Van Troys, Manor Askenazi, Christian J Gloeckner, Matthias Bauer, Jarrod A Marto, Christophe Ampe, Norbert Kinkl, Marius Ueffin. A QUICK screen for Lrrk2 interaction partners--leucine-rich repeat kinase 2 is involved in actin cytoskeleton dynamics. Molecular & cellular proteomics : MCP. vol 10. issue 1. 2011-04-06. PMID:20876399. |
mutations in human leucine-rich repeat kinase 2 (lrrk2), a protein of yet unknown function, are linked to parkinson's disease caused by degeneration of midbrain dopaminergic neurons. |
2011-04-06 |
2023-08-12 |
human |
| Andrea Meixner, Karsten Boldt, Marleen Van Troys, Manor Askenazi, Christian J Gloeckner, Matthias Bauer, Jarrod A Marto, Christophe Ampe, Norbert Kinkl, Marius Ueffin. A QUICK screen for Lrrk2 interaction partners--leucine-rich repeat kinase 2 is involved in actin cytoskeleton dynamics. Molecular & cellular proteomics : MCP. vol 10. issue 1. 2011-04-06. PMID:20876399. |
in developing dopaminergic midbrain primary neurons, lrrk2 knockdown results in shortened neurite processes, indicating a physiological role of lrrk2 in cytoskeletal organization and dynamics of dopaminergic neurons. |
2011-04-06 |
2023-08-12 |
human |
| Jonas A Hosp, Ana Pekanovic, Mengia S Rioult-Pedotti, Andreas R Luf. Dopaminergic projections from midbrain to primary motor cortex mediate motor skill learning. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 7. 2011-04-01. PMID:21325515. |
dopaminergic projections from midbrain to primary motor cortex mediate motor skill learning. |
2011-04-01 |
2023-08-12 |
rat |
| Jonas A Hosp, Ana Pekanovic, Mengia S Rioult-Pedotti, Andreas R Luf. Dopaminergic projections from midbrain to primary motor cortex mediate motor skill learning. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 7. 2011-04-01. PMID:21325515. |
other areas of cortex receive dopaminergic projections from the ventral tegmental area (vta) of the midbrain, and these projections are involved in learning phenomena. |
2011-04-01 |
2023-08-12 |
rat |
| Dietrich Haubenberger, Eva Reinthaler, Jakob C Mueller, Walter Pirker, Regina Katzenschlager, Roman Froehlich, Thomas Bruecke, Gerhard Daniel, Eduard Auff, Alexander Zimpric. Association of transcription factor polymorphisms PITX3 and EN1 with Parkinson's disease. Neurobiology of aging. vol 32. issue 2. 2011-03-30. PMID:19345444. |
the transcription factors pitx3 and engrailed 1 (en1), among others, have been shown to play a crucial role in the maturation and survival of midbrain dopaminergic neurons. |
2011-03-30 |
2023-08-12 |
Not clear |
| Jason R Cannon, Thomas Sew, Laura Montero, Edward A Burton, J Timothy Greenamyr. Pseudotype-dependent lentiviral transduction of astrocytes or neurons in the rat substantia nigra. Experimental neurology. vol 228. issue 1. 2011-03-30. PMID:21056560. |
vsv and mv pseudotypes transduced midbrain neurons, including a subset of nigral dopaminergic neurons. |
2011-03-30 |
2023-08-12 |
rat |
| Peter V Lovell, Claudio V Mell. Brain expression and song regulation of the cholecystokinin gene in the zebra finch (Taeniopygia guttata). The Journal of comparative neurology. vol 519. issue 2. 2011-03-18. PMID:21165972. |
using in situ hybridization we demonstrate that cck is highly expressed in several discrete brain regions, most prominently the caudalmost portion of the hippocampal formation, the caudodorsal nidopallial shelf and the caudomedial nidopallium (ncm), the core or shell regions of dorsal thalamic nuclei, dopaminergic cell groups in the mesencephalon and pons, the principal nucleus of the trigeminal nerve, and the dorsal raphe. |
2011-03-18 |
2023-08-12 |
Not clear |
| A Planken, L L Porokuokka, A-L Hänninen, R K Tuominen, J-O Andresso. Medium-throughput computer aided micro-island method to assay embryonic dopaminergic neuron cultures in vitro. Journal of neuroscience methods. vol 194. issue 1. 2011-03-16. PMID:20951734. |
in parkinson's disease (pd) midbrain dopaminergic (da) neurons degenerate and die, causing loss of motor function. |
2011-03-16 |
2023-08-12 |
mouse |
| Sen Li, Min Yin, Shuxi Liu, Yi Chen, Yanqing Yin, Tingxi Liu, Jiawei Zho. Expression of ventral diencephalon-enriched genes in zebrafish. Developmental dynamics : an official publication of the American Association of Anatomists. vol 239. issue 12. 2011-03-15. PMID:21061380. |
dopaminergic (da) neurons in the vertebrate di- and mesencephalon play essential roles in movement control, endocrine modulation and many other important physiological activities. |
2011-03-15 |
2023-08-12 |
zebrafish |
| Lauren A O'Connell, Miles R Fontenot, Hans A Hofman. Characterization of the dopaminergic system in the brain of an African cichlid fish, Astatotilapia burtoni. The Journal of comparative neurology. vol 519. issue 1. 2011-03-14. PMID:21120929. |
to understand better where dopamine acts to regulate social behavior in this species, we have determined the distribution of putative dopaminergic cells and fibers (by tyrosine hydroxylase immunohistochemistry) and dopamine receptors (by in situ hybridization for the d(1a) and d(2) dopamine receptor subtypes) throughout the forebrain and part of the mesencephalon of a. burtoni. |
2011-03-14 |
2023-08-12 |
Not clear |
| Massimiliano Caiazzo, Luca Colucci-D'Amato, Floriana Volpicelli, Luisa Speranza, Ciro Petrone, Lucio Pastore, Stefano Stifani, Francesco Ramirez, Gian Carlo Bellenchi, Umberto di Porzi. Krüppel-like factor 7 is required for olfactory bulb dopaminergic neuron development. Experimental cell research. vol 317. issue 4. 2011-03-08. PMID:21093432. |
interestingly, klf7-mutant mice show a dramatic reduction of th-positive neurons in the olfactory bulbs, but no change in gabaergic or midbrain dopaminergic neurons. |
2011-03-08 |
2023-08-12 |
mouse |
| Rowan P Orme, Monte A Gates, Rosemary A Fricker-Gate. A multiplexed quantitative proteomics approach for investigating protein expression in the developing central nervous system. Journal of neuroscience methods. vol 191. issue 1. 2011-03-07. PMID:20558204. |
briefly, total protein was extracted from embryonic ventral midbrain tissue before, during and after the birth of dopaminergic neurons, and digested using trypsin. |
2011-03-07 |
2023-08-12 |
Not clear |
| Jan-Christoph Schoene-Bake, Yaroslav Parpaley, Bernd Weber, Jaak Panksepp, Trevor A Hurwitz, Volker A Coene. Tractographic analysis of historical lesion surgery for depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 13. 2011-03-03. PMID:20736994. |
anatomically, convergence of these shared connectivities may derive from the superolateral branch of the medial forebrain bundle (mfb), a structure that connects these frontal areas to the origin of the mesolimbic dopaminergic 'reward' system in the midbrain ventral tegmental area. |
2011-03-03 |
2023-08-12 |
human |
| Devin Mueller, Christian Bravo-Rivera, Gregory J Quir. Infralimbic D2 receptors are necessary for fear extinction and extinction-related tone responses. Biological psychiatry. vol 68. issue 11. 2011-02-25. PMID:20926066. |
fear extinction is dependent on plasticity in the infralimbic prefrontal cortex, an area heavily innervated by midbrain dopaminergic inputs. |
2011-02-25 |
2023-08-12 |
Not clear |
| José-Manuel Baizabal, Concepción Valencia, Gilda Guerrero-Flores, Luis Covarrubia. Telencephalic neural precursor cells show transient competence to interpret the dopaminergic niche of the embryonic midbrain. Developmental biology. vol 349. issue 2. 2011-02-24. PMID:21070763. |
telencephalic neural precursor cells show transient competence to interpret the dopaminergic niche of the embryonic midbrain. |
2011-02-24 |
2023-08-12 |
mouse |
| José-Manuel Baizabal, Concepción Valencia, Gilda Guerrero-Flores, Luis Covarrubia. Telencephalic neural precursor cells show transient competence to interpret the dopaminergic niche of the embryonic midbrain. Developmental biology. vol 349. issue 2. 2011-02-24. PMID:21070763. |
the aim of this work was to test the competence of mouse telencephalic npcs to respond to the dopaminergic niche of the mesencephalon. |
2011-02-24 |
2023-08-12 |
mouse |
| José-Manuel Baizabal, Concepción Valencia, Gilda Guerrero-Flores, Luis Covarrubia. Telencephalic neural precursor cells show transient competence to interpret the dopaminergic niche of the embryonic midbrain. Developmental biology. vol 349. issue 2. 2011-02-24. PMID:21070763. |
telencephalic npcs isolated from midgestation mouse embryos (e10.5) and transplanted to age-matched mesencephalic explants efficiently differentiated into neurons but were largely unable to produce midbrain dopaminergic (mda) neurons. |
2011-02-24 |
2023-08-12 |
mouse |
| Anca R Radulesc. Mechanisms explaining transitions between tonic and phasic firing in neuronal populations as predicted by a low dimensional firing rate model. PloS one. vol 5. issue 9. 2011-02-18. PMID:20877649. |
the typical behavior of midbrain dopaminergic neurons in the rodent is used as an example to illustrate and interpret our results. |
2011-02-18 |
2023-08-12 |
Not clear |
| Yuki Kurauchi, Akinori Hisatsune, Yoichiro Isohama, Tomohiro Sawa, Takaaki Akaike, Koichi Shudo, Hiroshi Katsuk. Midbrain dopaminergic neurons utilize nitric oxide/cyclic GMP signaling to recruit ERK that links retinoic acid receptor stimulation to up-regulation of BDNF. Journal of neurochemistry. vol 116. issue 3. 2011-02-17. PMID:20649843. |
midbrain dopaminergic neurons utilize nitric oxide/cyclic gmp signaling to recruit erk that links retinoic acid receptor stimulation to up-regulation of bdnf. |
2011-02-17 |
2023-08-12 |
rat |
| Yuki Kurauchi, Akinori Hisatsune, Yoichiro Isohama, Tomohiro Sawa, Takaaki Akaike, Koichi Shudo, Hiroshi Katsuk. Midbrain dopaminergic neurons utilize nitric oxide/cyclic GMP signaling to recruit ERK that links retinoic acid receptor stimulation to up-regulation of BDNF. Journal of neurochemistry. vol 116. issue 3. 2011-02-17. PMID:20649843. |
stimulation of retinoic acid receptors (rars) protects midbrain dopaminergic neurons, presumably via up-regulation of brain-derived neurotrophic factor (bdnf) expression. |
2011-02-17 |
2023-08-12 |
rat |