| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Iu Ivliev. [Neurobiology of addictive behavior]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 61. issue 2. 2011-07-19. PMID:21675220. |
current neurophysiologic evidence suggests that the development of addiction is to some extent due to neurochemical stimulation of the midbrain dopaminergic system that is traditionally considered as a 'common neural currency' for rewards of most kinds. |
2011-07-19 |
2023-08-12 |
Not clear |
| Ana Sofia Correia, Sergey V Anisimov, Laurent Roybon, Jia-Yi Li, Patrik Brundi. Fibroblast growth factor-20 increases the yield of midbrain dopaminergic neurons derived from human embryonic stem cells. Frontiers in neuroanatomy. vol 1. 2011-07-14. PMID:18958198. |
fibroblast growth factor-20 increases the yield of midbrain dopaminergic neurons derived from human embryonic stem cells. |
2011-07-14 |
2023-08-12 |
mouse |
| Ana Sofia Correia, Sergey V Anisimov, Laurent Roybon, Jia-Yi Li, Patrik Brundi. Fibroblast growth factor-20 increases the yield of midbrain dopaminergic neurons derived from human embryonic stem cells. Frontiers in neuroanatomy. vol 1. 2011-07-14. PMID:18958198. |
in the central nervous system, fibroblast growth factor (fgf)-20 has been reported to act preferentially on midbrain dopaminergic neurons. |
2011-07-14 |
2023-08-12 |
mouse |
| Ana Sofia Correia, Sergey V Anisimov, Laurent Roybon, Jia-Yi Li, Patrik Brundi. Fibroblast growth factor-20 increases the yield of midbrain dopaminergic neurons derived from human embryonic stem cells. Frontiers in neuroanatomy. vol 1. 2011-07-14. PMID:18958198. |
the cultured cells also expressed other midbrain dopaminergic markers (pitx3, en1, msx1, and aldh1), suggesting that some had differentiated into midbrain dopaminergic neurons. |
2011-07-14 |
2023-08-12 |
mouse |
| Thomas F Münte, Marcus Heldmann, Hermann Hinrichs, Josep Marco-Pallares, Ulrike M Krämer, Volker Sturm, Hans-Jochen Heinz. Nucleus Accumbens is Involved in Human Action Monitoring: Evidence from Invasive Electrophysiological Recordings. Frontiers in human neuroscience. vol 1. 2011-07-14. PMID:18958225. |
action monitoring, that is, error detection and correction, is thought to be supported by a system involving the dopaminergic midbrain, the basal ganglia, and the medial prefrontal cortex. |
2011-07-14 |
2023-08-12 |
human |
| Thomas F Münte, Marcus Heldmann, Hermann Hinrichs, Josep Marco-Pallares, Ulrike M Krämer, Volker Sturm, Hans-Jochen Heinz. Nucleus Accumbens is Involved in Human Action Monitoring: Evidence from Invasive Electrophysiological Recordings. Frontiers in human neuroscience. vol 1. 2011-07-14. PMID:18958225. |
importantly, cross-correlation analysis showed that error-related activity in the nacc preceded surface activity by 40 ms. we propose that the nacc is involved in action monitoring, possibly by using error signals from the dopaminergic midbrain to adjust the relative impact of limbic and prefrontal inputs on frontal control systems in order to optimize goal-directed behavior. |
2011-07-14 |
2023-08-12 |
human |
| Ana Sofia Correia, Sergey V Anisimov, Jia-Yi Li, Patrik Brundi. Growth factors and feeder cells promote differentiation of human embryonic stem cells into dopaminergic neurons: a novel role for fibroblast growth factor-20. Frontiers in neuroscience. vol 2. issue 1. 2011-07-14. PMID:18982104. |
dopaminergic neurons can be derived from hescs and display a characteristic midbrain phenotype. |
2011-07-14 |
2023-08-12 |
mouse |
| Torsten Falk, Shiling Zhang, Scott J Sherma. Vascular endothelial growth factor B (VEGF-B) is up-regulated and exogenous VEGF-B is neuroprotective in a culture model of Parkinson's disease. Molecular neurodegeneration. vol 4. 2011-07-14. PMID:20003314. |
(1) we challenged rat midbrain cultures with rotenone (20 nm), a pesticide that has been shown to be toxic for dopaminergic neurons and that has been a well-characterized model of pd. |
2011-07-14 |
2023-08-12 |
rat |
| Susanne Graef, Guido Biele, Lea K Krugel, Frank Marzinzik, Michael Wahl, Johann Wotka, Fabian Klostermann, Hauke R Heekere. Differential influence of levodopa on reward-based learning in Parkinson's disease. Frontiers in human neuroscience. vol 4. 2011-07-14. PMID:21048900. |
the mesocorticolimbic dopamine (da) system linking the dopaminergic midbrain to the prefrontal cortex and subcortical striatum has been shown to be sensitive to reinforcement in animals and humans. |
2011-07-14 |
2023-08-12 |
Not clear |
| Tomás González-Hernández, Ignacio Cruz-Muros, Domingo Afonso-Oramas, Josmar Salas-Hernandez, Javier Castro-Hernande. Vulnerability of mesostriatal dopaminergic neurons in Parkinson's disease. Frontiers in neuroanatomy. vol 4. 2011-07-14. PMID:21079748. |
the term vulnerability was first associated with the midbrain dopaminergic neurons 85 years ago, before they were identified as monoaminergic neurons, when foix and nicolesco (1925) reported the loss of neuromelanin containing neurons in the midbrain of patients with post-encephalitic parkinson's disease (pd). |
2011-07-14 |
2023-08-12 |
Not clear |
| Tomás González-Hernández, Ignacio Cruz-Muros, Domingo Afonso-Oramas, Josmar Salas-Hernandez, Javier Castro-Hernande. Vulnerability of mesostriatal dopaminergic neurons in Parkinson's disease. Frontiers in neuroanatomy. vol 4. 2011-07-14. PMID:21079748. |
a few years later, hassler (1938) showed that degeneration is more intense in the ventral tier of the substantia nigra compacta than in its dorsal tier and the ventral tegmental area (vta), outlining the concept of differential vulnerability of midbrain dopaminergic (da-) neurons. |
2011-07-14 |
2023-08-12 |
Not clear |
| Jean-Luc Dreye. New insights into the roles of microRNAs in drug addiction and neuroplasticity. Genome medicine. vol 2. issue 12. 2011-07-14. PMID:21205279. |
recent studies have identified changes of several specific mirna expression profiles and polymorphisms affecting the interactions between mirnas and their targets in various brain disorders, including addiction: mir-16 causes adaptive changes in production of the serotonin transporter; mir-133b is specifically expressed in midbrain dopaminergic neurons, and regulates the production of tyrosine hydroxylase and the dopamine transporter; mir-212 affects production of striatal brain-derived neurotrophic factor and synaptic plasticity upon cocaine. |
2011-07-14 |
2023-08-12 |
Not clear |
| Jasmin Delic, Herbert Zimmerman. Nucleotides affect neurogenesis and dopaminergic differentiation of mouse fetal midbrain-derived neural precursor cells. Purinergic signalling. vol 6. issue 4. 2011-07-14. PMID:21437012. |
the fetal midbrain is a preferred source for isolating and producing dopaminergic neurons for subsequent grafting and replacement of damaged or lost dopaminergic midbrain neurons. |
2011-07-14 |
2023-08-12 |
mouse |
| Bobby Thomas, M Flint Bea. Molecular insights into Parkinson's disease. F1000 medicine reports. vol 3. 2011-07-14. PMID:21655332. |
parkinson's disease is a neurodegenerative movement disorder characterized by loss of midbrain dopaminergic neurons leading to motor abnormalities and autonomic dysfunctions. |
2011-07-14 |
2023-08-12 |
Not clear |
| Anna Zinger, Carlos Barcia, Maria Trinidad Herrero, Gilles J Guillemi. The involvement of neuroinflammation and kynurenine pathway in Parkinson's disease. Parkinson's disease. vol 2011. 2011-07-14. PMID:21687761. |
parkinson's disease (pd) is a common neurodegenerative disorder characterised by loss of dopaminergic neurons and localized neuroinflammation occurring in the midbrain several years before the actual onset of symptoms. |
2011-07-14 |
2023-08-12 |
Not clear |
| James P Dugan, Andrea Stratton, Hilary P Riley, W Todd Farmer, Grant S Mastic. Midbrain dopaminergic axons are guided longitudinally through the diencephalon by Slit/Robo signals. Molecular and cellular neurosciences. vol 46. issue 1. 2011-07-05. PMID:21118670. |
midbrain dopaminergic axons are guided longitudinally through the diencephalon by slit/robo signals. |
2011-07-05 |
2023-08-12 |
mouse |
| Kouta Kanno, Shoichi Ishiur. Differential effects of the HESR/HEY transcription factor family on dopamine transporter reporter gene expression via variable number of tandem repeats. Journal of neuroscience research. vol 89. issue 4. 2011-06-10. PMID:21290414. |
we also found that each hesr was expressed in the dopaminergic neurons in the mouse midbrain. |
2011-06-10 |
2023-08-12 |
mouse |
| T Kato, Y Abe, H Sotoyama, A Kakita, R Kominami, S Hirokawa, M Ozaki, H Takahashi, H Naw. Transient exposure of neonatal mice to neuregulin-1 results in hyperdopaminergic states in adulthood: implication in neurodevelopmental hypothesis for schizophrenia. Molecular psychiatry. vol 16. issue 3. 2011-06-03. PMID:20142818. |
human midbrain dopaminergic neurons highly express nrg1 receptors (erbb4). |
2011-06-03 |
2023-08-12 |
mouse |
| Tomoyuki Furuyashiki, Shuh Narumiy. Stress responses: the contribution of prostaglandin E(2) and its receptors. Nature reviews. Endocrinology. vol 7. issue 3. 2011-06-02. PMID:21116297. |
during psychological stress, ep1 suppresses impulsive behaviors via the midbrain dopaminergic systems. |
2011-06-02 |
2023-08-12 |
mouse |
| Kavita Prasad, Elizabeth Tarasewicz, Pamela A Ohman Strickland, Michael O'Neill, Stephen N Mitchell, Kalpana Merchant, Samnang Tep, Kathryn Hilton, Akash Datwani, Manuel Buttini, Sarah Mueller-Steiner, Eric K Richfiel. Biochemical and morphological consequences of human α-synuclein expression in a mouse α-synuclein null background. The European journal of neuroscience. vol 33. issue 4. 2011-05-31. PMID:21272100. |
hemizygous congenic mice did not exhibit any change in the number or size of dopaminergic neurons in the ventral midbrain at 9 months of age. |
2011-05-31 |
2023-08-12 |
mouse |