| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pingping Song, Dimitri Krain. Diverse Functions of Parkin in Midbrain Dopaminergic Neurons. Movement disorders : official journal of the Movement Disorder Society. 2024-06-11. PMID:38858837. |
diverse functions of parkin in midbrain dopaminergic neurons. |
2024-06-11 |
2024-06-14 |
human |
| Pingping Song, Dimitri Krain. Diverse Functions of Parkin in Midbrain Dopaminergic Neurons. Movement disorders : official journal of the Movement Disorder Society. 2024-06-11. PMID:38858837. |
parkinson's disease (pd) is characterized by preferential degeneration of midbrain dopaminergic neurons that contributes to its typical clinical manifestation. |
2024-06-11 |
2024-06-14 |
human |
| Pingping Song, Dimitri Krain. Diverse Functions of Parkin in Midbrain Dopaminergic Neurons. Movement disorders : official journal of the Movement Disorder Society. 2024-06-11. PMID:38858837. |
in pd patient neurons, disruption of this pathway on loss of parkin leads to defective recycling of synaptic vesicles and accumulation of toxic oxidized dopamine that at least in part explains preferential vulnerability of midbrain dopaminergic neurons. |
2024-06-11 |
2024-06-14 |
human |
| Gourav Chakraborty, Niladri Patr. Elucidating the Molecular Basis of 14-3-3 Interaction with α-Synuclein: Insights from Molecular Dynamics Simulations and the Design of a Novel Protein-Protein Interaction Inhibitor. The journal of physical chemistry. B. 2024-06-10. PMID:38857533. |
parkinson's disease is a widespread age-related neurodegenerative disorder characterized by the loss of dopaminergic neurons in the midbrain along with the appearance of protein aggregates, termed as "lewy bodies" in the surviving neuronal cells. |
2024-06-10 |
2024-06-14 |
human |
| Cintia Roodveldt, Liliana Bernardino, Ozgur Oztop-Cakmak, Milorad Dragic, Kari Espolin Fladmark, Sibel Ertan, Aktas Busra, Carlos Pita, Lucia Ciglar, Gaetan Garraux, Caroline Williams-Gray, Rodrigo Pacheco, Marina Romero-Ramo. The immune system in Parkinson's disease: what we know so far. Brain : a journal of neurology. 2024-06-04. PMID:38833182. |
parkinson's disease (pd) is characterised neuropathologically by the degeneration of dopaminergic neurons in the ventral midbrain, the accumulation of α-synuclein (α-syn) aggregates in neurons, and chronic neuroinflammation. |
2024-06-04 |
2024-06-06 |
Not clear |
| Tousif Jamal, Xuan Yan, Angelica da Silva Lantyer, Judith G Ter Horst, Tansu Celike. Experience-dependent regulation of dopaminergic signaling in the somatosensory cortex. Progress in neurobiology. 2024-06-04. PMID:38834131. |
these findings suggest that the dopaminergic drive originating from midbrain dopaminergic neurons, targeting the sensory cortex, is subject to experience-dependent regulation and might create a regulatory feed- back loop for modulating sensory processing. |
2024-06-04 |
2024-06-07 |
human |
| Sho K Sugawara, Yukio Nishimur. The Mesocortical System Encodes the Strength of Subsequent Force Generation. Neuroscience insights. vol 19. 2024-06-03. PMID:38827248. |
dopaminergic neurons located in the ventral midbrain (vm) are believed to be the center of incentive motivation. |
2024-06-03 |
2024-06-05 |
human |
| Sho K Sugawara, Yukio Nishimur. The Mesocortical System Encodes the Strength of Subsequent Force Generation. Neuroscience insights. vol 19. 2024-06-03. PMID:38827248. |
although the reaction time has been used as a proxy for incentive motivation mediated by dopaminergic midbrain activity, the premovement activity of the mesocortical pathway is involved in controlling the force strength rather than the initiation of subsequent force generation. |
2024-06-03 |
2024-06-05 |
human |
| Tania Arora, Gaurav Sharma, Vikash Prashar, Randeep Singh, Arti Sharma, Harish Changotra, Jyoti Parkas. Mechanistic Evaluation of miRNAs and Their Targeted Genes in the Pathogenesis and Therapeutics of Parkinson's Disease. Molecular neurobiology. 2024-06-01. PMID:38823001. |
pd is mainly caused by the demolition of the primary dopamine neurotransmitter secretory cells and dopaminergic or dopamine secretory neurons in the substantia nigra pars compacta of the midbrain, which are majorly responsible for motor functions. |
2024-06-01 |
2024-06-03 |
Not clear |
| Samir Kumar Beura, Gaurahari Sahoo, Sonika Yadav, Pooja Yadav, Abhishek Ramachandra Panigrahi, Sunil Kumar Sing. Investigating the role of rotenone on human blood platelets: Molecular insights into abnormal platelet functions in Parkinson's disease. Journal of biochemical and molecular toxicology. vol 38. issue 6. 2024-05-27. PMID:38800879. |
parkinson's disease (pd) is a predominant neuromotor disorder characterized by the selective death of dopaminergic neurons in the midbrain. |
2024-05-27 |
2024-05-31 |
human |
| Suelen L Boschen, Julian Seethaler, Shaohua Wang, Wendy D Lujan, Jodi L Silvernail, Rickey E Carter, Su-Youne Chang, J Luis Luja. Midbrain dopaminergic degeneration differentially modulates primary motor cortex activity and motor behavior in hemi-parkinsonian rats. Research square. 2024-05-27. PMID:38798359. |
midbrain dopaminergic degeneration differentially modulates primary motor cortex activity and motor behavior in hemi-parkinsonian rats. |
2024-05-27 |
2024-05-31 |
rat |
| Francantonio Devoto, Marika Mariano, Edoardo Gornetti, Eraldo Paulesu, Laura Zapparol. Trait food craving predicts functional connectivity between dopaminergic midbrain and the fusiform food area during eating imagery. Frontiers in psychiatry. vol 15. 2024-05-23. PMID:38774434. |
trait food craving predicts functional connectivity between dopaminergic midbrain and the fusiform food area during eating imagery. |
2024-05-23 |
2024-05-27 |
human |
| Francantonio Devoto, Marika Mariano, Edoardo Gornetti, Eraldo Paulesu, Laura Zapparol. Trait food craving predicts functional connectivity between dopaminergic midbrain and the fusiform food area during eating imagery. Frontiers in psychiatry. vol 15. 2024-05-23. PMID:38774434. |
neurofunctional coupling between the dopaminergic midbrain (i.e., ventral tegmental area, vta) and higher-order visual regions may contribute to food craving, leading to the onset or maintenance of obesity. |
2024-05-23 |
2024-05-27 |
human |
| Francantonio Devoto, Marika Mariano, Edoardo Gornetti, Eraldo Paulesu, Laura Zapparol. Trait food craving predicts functional connectivity between dopaminergic midbrain and the fusiform food area during eating imagery. Frontiers in psychiatry. vol 15. 2024-05-23. PMID:38774434. |
these findings emphasize the contribution of the functional coupling between dopaminergic midbrain and higher-order visual regions to food craving, suggesting a neurofunctional mechanism by which the mental representations of the hc food we like can become much more salient if not irresistible. |
2024-05-23 |
2024-05-27 |
human |
| Miguel Á Luján, Reana Young-Morrison, Sonia Aroni, István Katona, Miriam Melis, Joseph Chee. Dynamic Overrepresentation of Accumbal Cues in Food- and Opioid-Seeking Rats after Prenatal THC Exposure. bioRxiv : the preprint server for biology. 2024-05-20. PMID:38766015. |
previous research has identified midbrain dopaminergic neuronal alterations related to maternal thc consumption. |
2024-05-20 |
2024-05-27 |
rat |
| Huihui Hong, Jingdian Li, Tong Tong, Ting Yang, Hui Wang, Yudong Xu, Xiqin Lin, Jinxian Lin, Sicheng Liu, Kun Luo, Zhengping Yu, Wei Yuan, Huifeng Pi, Zhou Zho. Paraquat disrupts KIF5A-mediated axonal mitochondrial transport in midbrain neurons and its antagonism by melatonin. The Science of the total environment. vol 934. 2024-05-18. PMID:38750743. |
results showed that pq-induced motor deficits and midbrain dopaminergic neuronal damage in c57bl/6 j mice were protected by melatonin pretreatment. |
2024-05-18 |
2024-05-27 |
mouse |
| Pedro Rifes, Janko Kajtez, Josefine Rågård Christiansen, Alrik Schörling, Gaurav Singh Rathore, Daniel A Wolf, Andreas Heuer, Agnete Kirkeb. Forced LMX1A expression induces dorsal neural fates and disrupts patterning of human embryonic stem cells into ventral midbrain dopaminergic neurons. Stem cell reports. 2024-05-17. PMID:38759646. |
forced lmx1a expression induces dorsal neural fates and disrupts patterning of human embryonic stem cells into ventral midbrain dopaminergic neurons. |
2024-05-17 |
2024-05-27 |
human |
| Saba Afsheen, Ahmed Shaney Rehman, Azfar Jamal, Nazia Khan, Suhel Parve. Understanding Role of Pesticides in Development of Parkinson's Disease: Insights from Drosophila and Rodent Models. Ageing research reviews. 2024-05-17. PMID:38759892. |
parkinson's disease is a neurodegenerative illness linked to ageing, marked by the gradual decline of dopaminergic neurons in the midbrain. |
2024-05-17 |
2024-05-27 |
drosophila_melanogaster |
| Guoyi Tang, Yuan Guo, Ruotong Li, Yixuan Wang, Jie Yang, Shasha Gao, Jian Li. Lateral habenula 5-HT Neurochemistry international. 2024-05-16. PMID:38750961. |
lateral habenula 5-ht although the output of the lateral habenula (lhb) controls the activity of midbrain dopaminergic and serotonergic systems, which are implicated in the pathophysiology of anxiety, it is not clear the role of lhb 5-ht |
2024-05-16 |
2024-05-27 |
Not clear |
| Katarina Mihajlović, Gaia Ceddia, Noël Malod-Dognin, Gabriela Novak, Dimitrios Kyriakis, Alexander Skupin, Nataša Pržul. Multi-omics integration of scRNA-seq time series data predicts new intervention points for Parkinson's disease. Scientific reports. vol 14. issue 1. 2024-05-14. PMID:38744869. |
the onset of pd symptoms corresponds to 50% loss of midbrain dopaminergic (mda) neurons, limiting early-stage understanding of pd. |
2024-05-14 |
2024-05-27 |
Not clear |