| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carlos F Ibáñez, Jaan-Olle Andresso. Biology of GDNF and its receptors - Relevance for disorders of the central nervous system. Neurobiology of disease. vol 97. issue Pt B. 2018-02-12. PMID:26829643. |
a targeted effort to identify novel neurotrophic factors for midbrain dopaminergic neurons resulted in the isolation of gdnf (glial cell line-derived neurotrophic factor) from the supernatant of a rat glial cell line in 1993. |
2018-02-12 |
2023-08-13 |
rat |
| Maria Lindahl, Mart Saarma, Päivi Lindhol. Unconventional neurotrophic factors CDNF and MANF: Structure, physiological functions and therapeutic potential. Neurobiology of disease. vol 97. issue Pt B. 2018-02-12. PMID:27425895. |
cerebral dopamine neurotrophic factor (cdnf) and mesencephalic astrocyte-derived neurotrophic factor (manf) promote the survival of midbrain dopaminergic neurons which degenerate in parkinson's disease (pd). |
2018-02-12 |
2023-08-13 |
mouse |
| Pia Runeberg-Roos, Elisa Piccinini, Anna-Maija Penttinen, Kert Mätlik, Hanna Heikkinen, Satu Kuure, Maxim M Bespalov, Johan Peränen, Enrique Garea-Rodríguez, Eberhard Fuchs, Mikko Airavaara, Nisse Kalkkinen, Richard Penn, Mart Saarm. Developing therapeutically more efficient Neurturin variants for treatment of Parkinson's disease. Neurobiology of disease. vol 96. 2018-02-09. PMID:27425888. |
in parkinson's disease midbrain dopaminergic neurons degenerate and die. |
2018-02-09 |
2023-08-13 |
human |
| W Spencer Murch, Luke Clar. Games in the Brain: Neural Substrates of Gambling Addiction. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 22. issue 5. 2018-02-06. PMID:26116634. |
this article first delineates the neural circuitry that underpins gambling-related decision making, comprising ventral striatum, ventromedial prefrontal cortex, dopaminergic midbrain, and insula, and presents evidence for pathophysiology in this circuitry in gambling disorder. |
2018-02-06 |
2023-08-13 |
Not clear |
| Ajit Ranganath, Simon N Jaco. Doping the Mind: Dopaminergic Modulation of Prefrontal Cortical Cognition. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 22. issue 6. 2018-02-06. PMID:26338491. |
following a summary of the anatomy and physiology of the midbrain dopamine system, we focus on recent studies that investigated dopaminergic effects in prefrontal cortex at the cellular level. |
2018-02-06 |
2023-08-13 |
Not clear |
| Hélène Doucet-Beaupré, Catherine Gilbert, Marcos Schaan Profes, Audrey Chabrat, Consiglia Pacelli, Nicolas Giguère, Véronique Rioux, Julien Charest, Qiaolin Deng, Ariadna Laguna, Johan Ericson, Thomas Perlmann, Siew-Lan Ang, Francesca Cicchetti, Martin Parent, Louis-Eric Trudeau, Martin Lévesqu. Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 30. 2018-02-05. PMID:27407143. |
lmx1a and lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons. |
2018-02-05 |
2023-08-13 |
Not clear |
| Hélène Doucet-Beaupré, Catherine Gilbert, Marcos Schaan Profes, Audrey Chabrat, Consiglia Pacelli, Nicolas Giguère, Véronique Rioux, Julien Charest, Qiaolin Deng, Ariadna Laguna, Johan Ericson, Thomas Perlmann, Siew-Lan Ang, Francesca Cicchetti, Martin Parent, Louis-Eric Trudeau, Martin Lévesqu. Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 30. 2018-02-05. PMID:27407143. |
the lim-homeodomain transcription factors lmx1a and lmx1b play critical roles during the development of midbrain dopaminergic progenitors, but their functions in the adult brain remain poorly understood. |
2018-02-05 |
2023-08-13 |
Not clear |
| Hélène Doucet-Beaupré, Catherine Gilbert, Marcos Schaan Profes, Audrey Chabrat, Consiglia Pacelli, Nicolas Giguère, Véronique Rioux, Julien Charest, Qiaolin Deng, Ariadna Laguna, Johan Ericson, Thomas Perlmann, Siew-Lan Ang, Francesca Cicchetti, Martin Parent, Louis-Eric Trudeau, Martin Lévesqu. Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 30. 2018-02-05. PMID:27407143. |
we show here that sustained expression of lmx1a and lmx1b is required for the survival of adult midbrain dopaminergic neurons. |
2018-02-05 |
2023-08-13 |
Not clear |
| Kechun Yang, John I Broussard, Amber T Levine, Daniel Jenson, Benjamin R Arenkiel, John A Dan. Dopamine receptor activity participates in hippocampal synaptic plasticity associated with novel object recognition. The European journal of neuroscience. vol 45. issue 1. 2018-02-01. PMID:27646422. |
although da innervation arises from other sources and the main da signaling may be from those sources, our molecular approaches verified that midbrain dopaminergic fibers also sparsely innervate the dentate gyrus. |
2018-02-01 |
2023-08-13 |
mouse |
| Hongliang Yi, Xiaohang Bao, Xiaotong Tang, Xiaotang Fan, Haiwei X. Estrogen modulation of calretinin and BDNF expression in midbrain dopaminergic neurons of ovariectomised mice. Journal of chemical neuroanatomy. vol 77. 2018-01-31. PMID:27211874. |
estrogen modulation of calretinin and bdnf expression in midbrain dopaminergic neurons of ovariectomised mice. |
2018-01-31 |
2023-08-13 |
mouse |
| Ambreen Fatima, Saba Khanam, Rahul Rahul, Smita Jyoti, Falaq Naz, Fahad Ali, Yasir Hasan Siddiqu. Protective effect of tangeritin in transgenic Drosophila model of Parkinson's disease. Frontiers in bioscience (Elite edition). vol 9. 2018-01-31. PMID:27814588. |
parkinson's disease (pd) is a neurodegenerative disorder caused due to the loss of dopaminergic neurons in substantia nigra region of midbrain. |
2018-01-31 |
2023-08-13 |
drosophila_melanogaster |
| Madhumita Patel, Hyo Jung Moon, Ja Hye Hong, Byeongmoon Jeon. Chiro-Optical Modulation for NURR1 Production from Stem Cells. ACS chemical neuroscience. vol 8. issue 7. 2018-01-30. PMID:28452458. |
nuclear receptor related 1 (nurr1) is an essential protein for maintenance of dopaminergic neurons in adult midbrain of which deficiency leads to parkinson's disease. |
2018-01-30 |
2023-08-13 |
Not clear |
| Hyeonseok S Jeong, Sang-Rae Lee, Jieun E Kim, In Kyoon Lyoo, Sujung Yoon, Eun Namgung, Kyu-Tae Chang, Bom Sahn Kim, Sejung Yang, Jooyeon J Im, Saerom Jeon, Ilhyang Kang, Jiyoung Ma, Yong-An Chung, Soo Mee Li. Brain structural changes in cynomolgus monkeys administered with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: A longitudinal voxel-based morphometry and diffusion tensor imaging study. PloS one. vol 13. issue 1. 2018-01-29. PMID:29320500. |
gm volume initially increased after the mptp injection and gradually decreased in the striatum, midbrain, and other dopaminergic areas. |
2018-01-29 |
2023-08-13 |
monkey |
| P G Overton, N Vautrelle, P Redgrav. Sensory regulation of dopaminergic cell activity: Phenomenology, circuitry and function. Neuroscience. vol 282. 2018-01-26. PMID:24462607. |
evidence suggests that short-latency sensory information is provided to dopaminergic neurons by relatively primitive subcortical structures - including the midbrain superior colliculus for vision and the mesopontine parabrachial nucleus for pain and possibly gustation. |
2018-01-26 |
2023-08-12 |
Not clear |
| L Yetnikoff, H N Lavezzi, R A Reichard, D S Zah. An update on the connections of the ventral mesencephalic dopaminergic complex. Neuroscience. vol 282. 2018-01-26. PMID:24735820. |
this review covers the intrinsic organization and afferent and efferent connections of the midbrain dopaminergic complex, comprising the substantia nigra, ventral tegmental area and retrorubral field, which house, respectively, the a9, a10 and a8 groups of nigrostriatal, mesolimbic and mesocortical dopaminergic neurons. |
2018-01-26 |
2023-08-13 |
human |
| L Yetnikoff, H N Lavezzi, R A Reichard, D S Zah. An update on the connections of the ventral mesencephalic dopaminergic complex. Neuroscience. vol 282. 2018-01-26. PMID:24735820. |
associated intrinsic and extrinsic connections of the midbrain dopaminergic complex that utilize gamma-aminobutyric acid (gaba), glutamate and neuropeptides and various co-expressed combinations of these compounds are considered in conjunction with the dopamine-containing systems. |
2018-01-26 |
2023-08-13 |
human |
| L Yetnikoff, H N Lavezzi, R A Reichard, D S Zah. An update on the connections of the ventral mesencephalic dopaminergic complex. Neuroscience. vol 282. 2018-01-26. PMID:24735820. |
a framework is provided for understanding the organization of massive afferent systems descending and ascending to the midbrain dopaminergic complex from the telencephalon and brainstem, respectively. |
2018-01-26 |
2023-08-13 |
human |
| M Morales, D H Roo. Glutamate neurons within the midbrain dopamine regions. Neuroscience. vol 282. 2018-01-26. PMID:24875175. |
midbrain dopamine regions contain at least three neuronal phenotypes: dopaminergic, gabaergic, and glutamatergic. |
2018-01-26 |
2023-08-13 |
mouse |
| G E Gillies, K Virdee, S McArthur, J W Dalle. Sex-dependent diversity in ventral tegmental dopaminergic neurons and developmental programing: A molecular, cellular and behavioral analysis. Neuroscience. vol 282. 2018-01-26. PMID:24943715. |
this may be driven by sex differences in the hormonal environment during adulthood ('activational' effects) and development (perinatal and/or pubertal 'organizational' effects), as well as genetic factors, especially the sry gene on the y chromosome in males, which is expressed in a sub-population of adult midbrain dopaminergic neurons. |
2018-01-26 |
2023-08-13 |
Not clear |
| Linde Boekhoudt, Azar Omrani, Mieneke C M Luijendijk, Inge G Wolterink-Donselaar, Ellen C Wijbrans, Geoffrey van der Plasse, Roger A H Ada. Chemogenetic activation of dopamine neurons in the ventral tegmental area, but not substantia nigra, induces hyperactivity in rats. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 11. 2018-01-26. PMID:27712862. |
although hyperactivity has been linked to dopaminergic signalling, the causal relationship between midbrain dopamine neuronal activity and locomotor hyperactivity remains unknown. |
2018-01-26 |
2023-08-13 |
rat |