Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Pablo Ripollés, Josep Marco-Pallarés, Helena Alicart, Claus Tempelmann, Antoni Rodríguez-Fornells, Toemme Noessel. Intrinsic monitoring of learning success facilitates memory encoding via the activation of the SN/VTA-Hippocampal loop. eLife. vol 5. 2017-12-11. PMID:27644419. |
these results suggest that intrinsic-potentially reward-related-signals, triggered by self-monitoring of correct performance, can promote the storage of new information into long-term memory through the activation of the sn/vta-hippocampal loop, possibly via dopaminergic modulation of the midbrain. |
2017-12-11 |
2023-08-13 |
human |
Changsun Yu, Bok-Seok Kim, Eunhee Ki. FAF1 mediates regulated necrosis through PARP1 activation upon oxidative stress leading to dopaminergic neurodegeneration. Cell death and differentiation. vol 23. issue 11. 2017-12-11. PMID:27662363. |
indeed, the overexpression of faf1 using a recombinant adeno-associated virus system in the mouse ventral midbrain promoted parp1 activation and dopaminergic neurodegeneration in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) mouse model of parkinson's disease. |
2017-12-11 |
2023-08-13 |
mouse |
Chunhai Chen, Qinglong Ma, Ping Deng, Jianjing Yang, Lingling Yang, Min Lin, Zhengping Yu, Zhou Zho. Critical role of TRPC1 in thyroid hormone-dependent dopaminergic neuron development. Biochimica et biophysica acta. Molecular cell research. vol 1864. issue 10. 2017-12-06. PMID:28779972. |
thyroid hormones play a crucial role in midbrain dopaminergic (da) neuron development. |
2017-12-06 |
2023-08-13 |
Not clear |
Ninuo Xia, Fang Fang, Pengbo Zhang, Jun Cui, Chhavy Tep-Cullison, Tim Hamerley, Hyun Joo Lee, Theo Palmer, Brian Bothner, Jin Hyung Lee, Renee Reijo Per. A Knockin Reporter Allows Purification and Characterization of mDA Neurons from Heterogeneous Populations. Cell reports. vol 18. issue 10. 2017-11-28. PMID:28273465. |
generation of midbrain dopaminergic (mda) neurons from human pluripotent stem cells provides a platform for inquiry into basic and translational studies of parkinson's disease (pd). |
2017-11-28 |
2023-08-13 |
human |
Tim Kao, Tanya Labonne, Jonathan C Niclis, Ritu Chaurasia, Zerina Lokmic, Elizabeth Qian, Freya F Bruveris, Sara E Howden, Ali Motazedian, Jacqueline V Schiesser, Magdaline Costa, Koula Sourris, Elizabeth Ng, David Anderson, Antonietta Giudice, Peter Farlie, Michael Cheung, Shireen R Lamande, Anthony J Penington, Clare L Parish, Lachlan H Thomson, Arash Rafii, David A Elliott, Andrew G Elefanty, Edouard G Stanle. GAPTrap: A Simple Expression System for Pluripotent Stem Cells and Their Derivatives. Stem cell reports. vol 7. issue 3. 2017-11-21. PMID:27594589. |
differentiation experiments showed that reporter expression was reliably maintained in hematopoietic cells, cardiac mesoderm, definitive endoderm, and ventral midbrain dopaminergic neurons. |
2017-11-21 |
2023-08-13 |
human |
Du Fang, Yu Qing, Shijun Yan, Doris Chen, Shirley ShiDu Ya. Development and Dynamic Regulation of Mitochondrial Network in Human Midbrain Dopaminergic Neurons Differentiated from iPSCs. Stem cell reports. vol 7. issue 4. 2017-11-21. PMID:27666790. |
development and dynamic regulation of mitochondrial network in human midbrain dopaminergic neurons differentiated from ipscs. |
2017-11-21 |
2023-08-13 |
human |
Zhan-Ying Hu, Bo Chen, Jing-Pu Zhang, Yuan-Yuan M. Up-regulation of autophagy-related gene 5 ( The Journal of biological chemistry. vol 292. issue 44. 2017-11-21. PMID:28928221. |
up-regulation of autophagy-related gene 5 ( parkinson's disease (pd) is one of the most epidemic neurodegenerative diseases and is characterized by movement disorders arising from loss of midbrain dopaminergic (da) neurons. |
2017-11-21 |
2023-08-13 |
Not clear |
Ima Trempler, Anne-Marike Schiffer, Nadiya El-Sourani, Christiane Ahlheim, Gereon R Fink, Ricarda I Schubot. Frontostriatal Contribution to the Interplay of Flexibility and Stability in Serial Prediction. Journal of cognitive neuroscience. vol 29. issue 2. 2017-11-20. PMID:27626228. |
finally, we observed that the dopaminergic midbrain modulates the transition between different cognitive states, thresholded by participants' individual performance history in response to temporal environmental demands. |
2017-11-20 |
2023-08-13 |
human |
Sarah X Luo, Leah Timbang, Jae-Ick Kim, Yulei Shang, Kadellyn Sandoval, Amy A Tang, Jennifer L Whistler, Jun B Ding, Eric J Huan. TGF-β Signaling in Dopaminergic Neurons Regulates Dendritic Growth, Excitatory-Inhibitory Synaptic Balance, and Reversal Learning. Cell reports. vol 17. issue 12. 2017-11-20. PMID:28009292. |
neural circuits involving midbrain dopaminergic (da) neurons regulate reward and goal-directed behaviors. |
2017-11-20 |
2023-08-13 |
mouse |
Francesco Rigoli, Benjamin Chew, Peter Dayan, Raymond J Dola. The Dopaminergic Midbrain Mediates an Effect of Average Reward on Pavlovian Vigor. Journal of cognitive neuroscience. vol 28. issue 9. 2017-11-17. PMID:27082045. |
the dopaminergic midbrain mediates an effect of average reward on pavlovian vigor. |
2017-11-17 |
2023-08-13 |
human |
Francesco Rigoli, Benjamin Chew, Peter Dayan, Raymond J Dola. The Dopaminergic Midbrain Mediates an Effect of Average Reward on Pavlovian Vigor. Journal of cognitive neuroscience. vol 28. issue 9. 2017-11-17. PMID:27082045. |
greater average reward was associated with enhanced activity in dopaminergic midbrain to a degree that correlated with the relationship between average reward and pressing vigor. |
2017-11-17 |
2023-08-13 |
human |
Francesco Rigoli, Benjamin Chew, Peter Dayan, Raymond J Dola. The Dopaminergic Midbrain Mediates an Effect of Average Reward on Pavlovian Vigor. Journal of cognitive neuroscience. vol 28. issue 9. 2017-11-17. PMID:27082045. |
these findings highlight a crucial role for dopaminergic midbrain in representing aspects of average reward and motivational vigor. |
2017-11-17 |
2023-08-13 |
human |
Jaron T Colas, Wolfgang M Pauli, Tobias Larsen, J Michael Tyszka, John P O'Dohert. Distinct prediction errors in mesostriatal circuits of the human brain mediate learning about the values of both states and actions: evidence from high-resolution fMRI. PLoS computational biology. vol 13. issue 10. 2017-11-13. PMID:29049406. |
prediction-error signals consistent with formal models of "reinforcement learning" (rl) have repeatedly been found within dopaminergic nuclei of the midbrain and dopaminoceptive areas of the striatum. |
2017-11-13 |
2023-08-13 |
human |
Jaron T Colas, Wolfgang M Pauli, Tobias Larsen, J Michael Tyszka, John P O'Dohert. Distinct prediction errors in mesostriatal circuits of the human brain mediate learning about the values of both states and actions: evidence from high-resolution fMRI. PLoS computational biology. vol 13. issue 10. 2017-11-13. PMID:29049406. |
to test for the presence of these prediction-error signals in the brain, we scanned human participants with a high-resolution functional magnetic-resonance imaging (fmri) protocol optimized to enable measurement of neural activity in the dopaminergic midbrain as well as the striatal areas to which it projects. |
2017-11-13 |
2023-08-13 |
human |
Thomas G McWilliams, Laura Howard, Sean Wyatt, Alun M Davie. TNF superfamily member APRIL enhances midbrain dopaminergic axon growth and contributes to the nigrostriatal projection in vivo. Experimental neurology. vol 298. issue Pt A. 2017-11-06. PMID:28911883. |
tnf superfamily member april enhances midbrain dopaminergic axon growth and contributes to the nigrostriatal projection in vivo. |
2017-11-06 |
2023-08-13 |
mouse |
Thomas G McWilliams, Laura Howard, Sean Wyatt, Alun M Davie. TNF superfamily member APRIL enhances midbrain dopaminergic axon growth and contributes to the nigrostriatal projection in vivo. Experimental neurology. vol 298. issue Pt A. 2017-11-06. PMID:28911883. |
we have studied the role of the tumor necrosis factor superfamily member april in the development of embryonic mouse midbrain dopaminergic neurons in vitro and in vivo. |
2017-11-06 |
2023-08-13 |
mouse |
Thomas G McWilliams, Laura Howard, Sean Wyatt, Alun M Davie. TNF superfamily member APRIL enhances midbrain dopaminergic axon growth and contributes to the nigrostriatal projection in vivo. Experimental neurology. vol 298. issue Pt A. 2017-11-06. PMID:28911883. |
the axon growth-enhancing effect of april was similar to that of glial cell-derived neurotrophic factor (gdnf), but in contrast to gdnf, april did not promote the survival of midbrain dopaminergic neurons. |
2017-11-06 |
2023-08-13 |
mouse |
Thomas G McWilliams, Laura Howard, Sean Wyatt, Alun M Davie. TNF superfamily member APRIL enhances midbrain dopaminergic axon growth and contributes to the nigrostriatal projection in vivo. Experimental neurology. vol 298. issue Pt A. 2017-11-06. PMID:28911883. |
in vivo, there was a significant reduction in the density of midbrain dopaminergic projections to the striatum in april-/- embryos compared with wild type littermates at e14. |
2017-11-06 |
2023-08-13 |
mouse |
Xue-Yuan Niu, Hou-Ju Huang, Jin-Bao Zhang, Chan Zhang, Wei-Guang Chen, Chen-You Sun, Yu-Qiang Ding, Min Lia. Deletion of autophagy-related gene 7 in dopaminergic neurons prevents their loss induced by MPTP. Neuroscience. vol 339. 2017-10-30. PMID:27693472. |
parkinson's disease (pd) is a neurodegenerative disease caused by a gradual loss of midbrain dopaminergic (mda) neurons in the substantia nigra pars compacta (snpc) during aging. |
2017-10-30 |
2023-08-13 |
mouse |
Anja Drinkut, Karsten Tillack, Durga P Meka, Jorg B Schulz, Sebastian Kügler, Edgar R Krame. Ret is essential to mediate GDNF's neuroprotective and neuroregenerative effect in a Parkinson disease mouse model. Cell death & disease. vol 7. issue 9. 2017-10-25. PMID:27607574. |
strikingly, in this established pd mouse model, the absence of ret completely abolished gdnf's neuroprotective and regenerative effect on the midbrain dopaminergic system. |
2017-10-25 |
2023-08-13 |
mouse |