| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Heike Stockner, Petra Schwingenschuh, Atbin Djamshidian, Laura Silveira-Moriyama, Petra Katschnig, Klaus Seppi, John Dickson, Mark J Edwards, Andrew J Lees, Werner Poewe, Kailash P Bhati. Is transcranial sonography useful to distinguish scans without evidence of dopaminergic deficit patients from Parkinson's disease? Movement disorders : official journal of the Movement Disorder Society. vol 27. issue 9. 2012-12-17. PMID:22744819. |
the aim of this study was to investigate the prevalence of midbrain hyperechogenicity in patients with suspected parkinsonism and scans without evidence of dopaminergic deficit (swedd), in comparison to pd patients. |
2012-12-17 |
2023-08-12 |
Not clear |
| Changgeng Peng, Na Li, Yen-Kar Ng, Jingzhong Zhang, Florian Meier, Fabian J Theis, Matthias Merkenschlager, Wei Chen, Wolfgang Wurst, Nilima Prakas. A unilateral negative feedback loop between miR-200 microRNAs and Sox2/E2F3 controls neural progenitor cell-cycle exit and differentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 38. 2012-12-03. PMID:22993445. |
we show that the mir-200 family plays a crucial role for the proper generation and survival of ventral neuronal populations in the murine midbrain/hindbrain region, including midbrain dopaminergic neurons, by directly targeting the pluripotency factor sox2 and the cell-cycle regulator e2f3 in neural stem/progenitor cells. |
2012-12-03 |
2023-08-12 |
mouse |
| Ayse Ulusoy, Tomas Björklund, Kerstin Buck, Deniz Kiri. Dysregulated dopamine storage increases the vulnerability to α-synuclein in nigral neurons. Neurobiology of disease. vol 47. issue 3. 2012-11-29. PMID:22659302. |
impairments in the capacity of dopaminergic neurons to handle cytoplasmic dopamine may be a critical factor underlying the selective vulnerability of midbrain dopamine neurons in parkinson's disease. |
2012-11-29 |
2023-08-12 |
mouse |
| Xi Lu, Jeong S Kim-Han, Karen L O'Malley, Shelly E Sakiyama-Elber. A microdevice platform for visualizing mitochondrial transport in aligned dopaminergic axons. Journal of neuroscience methods. vol 209. issue 1. 2012-11-23. PMID:22652340. |
studies of mitochondrial transport along single axons are difficult with traditional dissociated culture systems and the fragility of the midbrain dopaminergic cultures precludes their survival in previously developed microfluidic devices with an enclosed architecture. |
2012-11-23 |
2023-08-12 |
Not clear |
| Xi Lu, Jeong S Kim-Han, Karen L O'Malley, Shelly E Sakiyama-Elber. A microdevice platform for visualizing mitochondrial transport in aligned dopaminergic axons. Journal of neuroscience methods. vol 209. issue 1. 2012-11-23. PMID:22652340. |
dopaminergic neurons from midbrain cultures were successfully cultured within the microdevices for up to 4 weeks and extended their axons across the microchannels. |
2012-11-23 |
2023-08-12 |
Not clear |
| Yu Lu. The function and mechanisms of Nurr1 action in midbrain dopaminergic neurons, from development and maintenance to survival. International review of neurobiology. vol 102. 2012-11-21. PMID:22748824. |
the function and mechanisms of nurr1 action in midbrain dopaminergic neurons, from development and maintenance to survival. |
2012-11-21 |
2023-08-12 |
mouse |
| Yu Lu. The function and mechanisms of Nurr1 action in midbrain dopaminergic neurons, from development and maintenance to survival. International review of neurobiology. vol 102. 2012-11-21. PMID:22748824. |
nurr1 is critical for the development and maintenance of midbrain dopaminergic (da) neurons in mouse. |
2012-11-21 |
2023-08-12 |
mouse |
| Yu Lu. The function and mechanisms of Nurr1 action in midbrain dopaminergic neurons, from development and maintenance to survival. International review of neurobiology. vol 102. 2012-11-21. PMID:22748824. |
in vivo nuip protein is largely colocalized with nurr1 in adult midbrain dopaminergic neurons. |
2012-11-21 |
2023-08-12 |
mouse |
| Jian Yang, Xuan Wang, Yue Wang, Zi-Xuan Guo, Ding-Zhen Luo, Jun Jia, Xiao-Min Wan. Dopaminergic neuronal conversion from adult rat skeletal muscle-derived stem cells in vitro. Neurochemical research. vol 37. issue 9. 2012-11-20. PMID:22723079. |
subsequently, these neurosphere-like cell clusters were further directed to dopaminergic differentiation through two major induction steps, patterning to midbrain progenitors with sonic hedgehog and fibroblast growth factor 8, followed by the differentiation to dopaminergic neurons with neurotrophic factors (glial cell line-derived neurotrophic factor) and chemicals (ascorbic acid, forskolin). |
2012-11-20 |
2023-08-12 |
rat |
| Kosuke Hamaguchi, Richard Moone. Recurrent interactions between the input and output of a songbird cortico-basal ganglia pathway are implicated in vocal sequence variability. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 34. 2012-11-19. PMID:22915110. |
these experiments indicate that activity travels to hvc through at least two independent ipsilateral pathways, one of which involves fast signaling through a midbrain dopaminergic cell group, reminiscent of recurrent mesocortical loops described in mammals. |
2012-11-19 |
2023-08-12 |
Not clear |
| Laia Lladó-Pelfort, Noemí Santana, Valentina Ghisi, Francesc Artigas, Pau Celad. 5-HT1A receptor agonists enhance pyramidal cell firing in prefrontal cortex through a preferential action on GABA interneurons. Cerebral cortex (New York, N.Y. : 1991). vol 22. issue 7. 2012-11-13. PMID:21893679. |
this results in pyramidal disinhibition and subsequent downstream excitations of subcortical structures reciprocally connected with pfc, such as midbrain dopaminergic neurons. |
2012-11-13 |
2023-08-12 |
rat |
| Ruth M Krebs, Carsten N Boehler, Kenneth C Roberts, Allen W Song, Marty G Woldorf. The involvement of the dopaminergic midbrain and cortico-striatal-thalamic circuits in the integration of reward prospect and attentional task demands. Cerebral cortex (New York, N.Y. : 1991). vol 22. issue 3. 2012-11-01. PMID:21680848. |
the involvement of the dopaminergic midbrain and cortico-striatal-thalamic circuits in the integration of reward prospect and attentional task demands. |
2012-11-01 |
2023-08-12 |
human |
| Ruth M Krebs, Carsten N Boehler, Kenneth C Roberts, Allen W Song, Marty G Woldorf. The involvement of the dopaminergic midbrain and cortico-striatal-thalamic circuits in the integration of reward prospect and attentional task demands. Cerebral cortex (New York, N.Y. : 1991). vol 22. issue 3. 2012-11-01. PMID:21680848. |
together, the data demonstrate that expected value and attentional demands are integrated in cortico-striatal-thalamic circuits in coordination with the dopaminergic midbrain to flexibly modulate resource allocation for an effective pursuit of behavioral goals. |
2012-11-01 |
2023-08-12 |
human |
| Mary P Heyer, Amar K Pani, Richard J Smeyne, Paul J Kenny, Guoping Fen. Normal midbrain dopaminergic neuron development and function in miR-133b mutant mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 32. 2012-10-26. PMID:22875923. |
midbrain dopaminergic (mda) neurons control movement and emotion, and their degeneration leads to motor and cognitive defects in parkinson's disease (pd). |
2012-10-26 |
2023-08-12 |
mouse |
| Yosif M Ganat, Elizabeth L Calder, Sonja Kriks, Jenny Nelander, Edmund Y Tu, Fan Jia, Daniela Battista, Neil Harrison, Malin Parmar, Mark J Tomishima, Urs Rutishauser, Lorenz Stude. Identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment. The Journal of clinical investigation. vol 122. issue 8. 2012-10-25. PMID:22751106. |
identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment. |
2012-10-25 |
2023-08-12 |
mouse |
| Yosif M Ganat, Elizabeth L Calder, Sonja Kriks, Jenny Nelander, Edmund Y Tu, Fan Jia, Daniela Battista, Neil Harrison, Malin Parmar, Mark J Tomishima, Urs Rutishauser, Lorenz Stude. Identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment. The Journal of clinical investigation. vol 122. issue 8. 2012-10-25. PMID:22751106. |
embryonic stem cells (escs) represent a promising source of midbrain dopaminergic (da) neurons for applications in parkinson disease. |
2012-10-25 |
2023-08-12 |
mouse |
| Ben Yang, Lauren B Geary, Yong-Chao M. In ovo electroporation in chick midbrain for studying gene function in dopaminergic neuron development. Journal of visualized experiments : JoVE. issue 66. 2012-10-22. PMID:22895156. |
dopaminergic neurons located in the ventral midbrain control movement, emotional behavior, and reward mechanisms. |
2012-10-22 |
2023-08-12 |
human |
| Ben Yang, Lauren B Geary, Yong-Chao M. In ovo electroporation in chick midbrain for studying gene function in dopaminergic neuron development. Journal of visualized experiments : JoVE. issue 66. 2012-10-22. PMID:22895156. |
the dysfunction of ventral midbrain dopaminergic neurons is implicated in parkinson's disease, schizophrenia, depression, and dementia. |
2012-10-22 |
2023-08-12 |
human |
| Ben Yang, Lauren B Geary, Yong-Chao M. In ovo electroporation in chick midbrain for studying gene function in dopaminergic neuron development. Journal of visualized experiments : JoVE. issue 66. 2012-10-22. PMID:22895156. |
dopaminergic neurons differentiate from neural progenitors lining the ventricular zone of embryonic ventral midbrain. |
2012-10-22 |
2023-08-12 |
human |
| Christian M Nefzger, Colin T Su, Stewart A Fabb, Brigham J Hartley, Siew J Beh, Wendy R Zeng, John M Haynes, Colin W Pouto. Lmx1a allows context-specific isolation of progenitors of GABAergic or dopaminergic neurons during neural differentiation of embryonic stem cells. Stem cells (Dayton, Ohio). vol 30. issue 7. 2012-10-19. PMID:22495882. |
lim homeobox transcription factor 1 alpha (lmx1a) is required for the development of midbrain dopaminergic neurons, roof plate formation, and cortical hem development. |
2012-10-19 |
2023-08-12 |
mouse |