| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sangram S Parelkar, Juan G Cadena, Chul Kim, Zhaohui Wang, Rachel Sugal, Brooke Bentley, Luis Moral, Helen C Ardley, Lawrence M Schwart. The parkin-like human homolog of Drosophila ariadne-1 (HHARI) can induce aggresome formation in mammalian cells and is immunologically detectable in Lewy bodies. Journal of molecular neuroscience : MN. vol 46. issue 1. 2013-01-24. PMID:21590270. |
loss of functional parkin is responsible for the death of midbrain dopaminergic neurons in human autosomal recessive juvenile parkinsonism. |
2013-01-24 |
2023-08-12 |
human |
| M Maral Mouradia. MicroRNAs in Parkinson's disease. Neurobiology of disease. vol 46. issue 2. 2013-01-24. PMID:22245218. |
in midbrain dopaminergic neurons, which degenerate in parkinson's disease (pd) causing motor signs and symptoms, disruption of this network results in their progressive loss associated with impaired motor activity in drosophila and mouse models. |
2013-01-24 |
2023-08-12 |
mouse |
| Anne-Marike Schiffer, Christiane Ahlheim, Moritz F Wurm, Ricarda I Schubot. Surprised at all the entropy: hippocampal, caudate and midbrain contributions to learning from prediction errors. PloS one. vol 7. issue 5. 2013-01-24. PMID:22570715. |
the present fmri study used an action-observation paradigm to investigate the contributions of the hippocampus, caudate nucleus and midbrain dopaminergic system to different types of learning: learning in the absence of prediction errors, learning from prediction errors, and responding to the accumulation of prediction errors in unpredictable stimulus configurations. |
2013-01-24 |
2023-08-12 |
Not clear |
| Anne-Marike Schiffer, Christiane Ahlheim, Moritz F Wurm, Ricarda I Schubot. Surprised at all the entropy: hippocampal, caudate and midbrain contributions to learning from prediction errors. PloS one. vol 7. issue 5. 2013-01-24. PMID:22570715. |
in sum, we established that the midbrain dopaminergic system, the hippocampus, and the caudate nucleus were to different degrees significantly involved in the three different types of learning: acquisition of new information, learning from prediction errors and responding to unpredictable stimulus developments. |
2013-01-24 |
2023-08-12 |
Not clear |
| Christine Esslinger, Susanne Englisch, Dragos Inta, Franziska Rausch, Frederike Schirmbeck, Daniela Mier, Peter Kirsch, Andreas Meyer-Lindenberg, Mathias Zin. Ventral striatal activation during attribution of stimulus saliency and reward anticipation is correlated in unmedicated first episode schizophrenia patients. Schizophrenia research. vol 140. issue 1-3. 2013-01-18. PMID:22784688. |
several functional magnetic resonance imaging (fmri) investigations revealed neurobiological correlates of these deficits, raising the hypothesis of a common basis in midbrain dopaminergic signaling. |
2013-01-18 |
2023-08-12 |
human |
| Marcel M Daadi, Brad A Grueter, Robert C Malenka, D Eugene Redmond, Gary K Steinber. Dopaminergic neurons from midbrain-specified human embryonic stem cell-derived neural stem cells engrafted in a monkey model of Parkinson's disease. PloS one. vol 7. issue 7. 2013-01-16. PMID:22815935. |
parkinson's disease (pd) is a neurological disorder characterized by the loss of midbrain dopaminergic (da) neurons. |
2013-01-16 |
2023-08-12 |
human |
| Wen-Liang Zhou, Srdjan D Anti. Rapid dopaminergic and GABAergic modulation of calcium and voltage transients in dendrites of prefrontal cortex pyramidal neurons. The Journal of physiology. vol 590. issue 16. 2013-01-08. PMID:22641784. |
the spatio-temporal pattern of dendritic calcium suppression described in this paper is expected to occur during phasic dopaminergic signalling, when midbrain dopaminergic neurons generate a transient (0.5 s) burst of aps in response to a salient event. |
2013-01-08 |
2023-08-12 |
Not clear |
| Anne K Meyer, Alexander Jarosch, Katja Schurig, Ina Nuesslein, Stefan Kißenkötter, Alexander Storc. Fetal mouse mesencephalic NPCs generate dopaminergic neurons from post-mitotic precursors and maintain long-term neural but not dopaminergic potential in vitro. Brain research. vol 1474. 2013-01-08. PMID:22842082. |
we investigated the proliferative behavior and dopaminergic differentiation capacity of fetal mouse midbrain npcs derived from e10 to e14 embryos expanded either as neurosphere or monolayer culture. |
2013-01-08 |
2023-08-12 |
mouse |
| Anne K Meyer, Alexander Jarosch, Katja Schurig, Ina Nuesslein, Stefan Kißenkötter, Alexander Storc. Fetal mouse mesencephalic NPCs generate dopaminergic neurons from post-mitotic precursors and maintain long-term neural but not dopaminergic potential in vitro. Brain research. vol 1474. 2013-01-08. PMID:22842082. |
we did not find dopaminergic differentiation in long-term expanded mouse npc types, which is in contrast to rat and human fetal midbrain npcs. |
2013-01-08 |
2023-08-12 |
mouse |
| Heike Stockner, Petra Schwingenschuh, Atbin Djamshidian, Laura Silveira-Moriyama, Petra Katschnig, Klaus Seppi, John Dickson, Mark J Edwards, Andrew J Lees, Werner Poewe, Kailash P Bhati. Is transcranial sonography useful to distinguish scans without evidence of dopaminergic deficit patients from Parkinson's disease? Movement disorders : official journal of the Movement Disorder Society. vol 27. issue 9. 2012-12-17. PMID:22744819. |
the aim of this study was to investigate the prevalence of midbrain hyperechogenicity in patients with suspected parkinsonism and scans without evidence of dopaminergic deficit (swedd), in comparison to pd patients. |
2012-12-17 |
2023-08-12 |
Not clear |
| Changgeng Peng, Na Li, Yen-Kar Ng, Jingzhong Zhang, Florian Meier, Fabian J Theis, Matthias Merkenschlager, Wei Chen, Wolfgang Wurst, Nilima Prakas. A unilateral negative feedback loop between miR-200 microRNAs and Sox2/E2F3 controls neural progenitor cell-cycle exit and differentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 38. 2012-12-03. PMID:22993445. |
we show that the mir-200 family plays a crucial role for the proper generation and survival of ventral neuronal populations in the murine midbrain/hindbrain region, including midbrain dopaminergic neurons, by directly targeting the pluripotency factor sox2 and the cell-cycle regulator e2f3 in neural stem/progenitor cells. |
2012-12-03 |
2023-08-12 |
mouse |
| Ayse Ulusoy, Tomas Björklund, Kerstin Buck, Deniz Kiri. Dysregulated dopamine storage increases the vulnerability to α-synuclein in nigral neurons. Neurobiology of disease. vol 47. issue 3. 2012-11-29. PMID:22659302. |
impairments in the capacity of dopaminergic neurons to handle cytoplasmic dopamine may be a critical factor underlying the selective vulnerability of midbrain dopamine neurons in parkinson's disease. |
2012-11-29 |
2023-08-12 |
mouse |
| Xi Lu, Jeong S Kim-Han, Karen L O'Malley, Shelly E Sakiyama-Elber. A microdevice platform for visualizing mitochondrial transport in aligned dopaminergic axons. Journal of neuroscience methods. vol 209. issue 1. 2012-11-23. PMID:22652340. |
studies of mitochondrial transport along single axons are difficult with traditional dissociated culture systems and the fragility of the midbrain dopaminergic cultures precludes their survival in previously developed microfluidic devices with an enclosed architecture. |
2012-11-23 |
2023-08-12 |
Not clear |
| Xi Lu, Jeong S Kim-Han, Karen L O'Malley, Shelly E Sakiyama-Elber. A microdevice platform for visualizing mitochondrial transport in aligned dopaminergic axons. Journal of neuroscience methods. vol 209. issue 1. 2012-11-23. PMID:22652340. |
dopaminergic neurons from midbrain cultures were successfully cultured within the microdevices for up to 4 weeks and extended their axons across the microchannels. |
2012-11-23 |
2023-08-12 |
Not clear |
| Yu Lu. The function and mechanisms of Nurr1 action in midbrain dopaminergic neurons, from development and maintenance to survival. International review of neurobiology. vol 102. 2012-11-21. PMID:22748824. |
the function and mechanisms of nurr1 action in midbrain dopaminergic neurons, from development and maintenance to survival. |
2012-11-21 |
2023-08-12 |
mouse |
| Yu Lu. The function and mechanisms of Nurr1 action in midbrain dopaminergic neurons, from development and maintenance to survival. International review of neurobiology. vol 102. 2012-11-21. PMID:22748824. |
nurr1 is critical for the development and maintenance of midbrain dopaminergic (da) neurons in mouse. |
2012-11-21 |
2023-08-12 |
mouse |
| Yu Lu. The function and mechanisms of Nurr1 action in midbrain dopaminergic neurons, from development and maintenance to survival. International review of neurobiology. vol 102. 2012-11-21. PMID:22748824. |
in vivo nuip protein is largely colocalized with nurr1 in adult midbrain dopaminergic neurons. |
2012-11-21 |
2023-08-12 |
mouse |
| Jian Yang, Xuan Wang, Yue Wang, Zi-Xuan Guo, Ding-Zhen Luo, Jun Jia, Xiao-Min Wan. Dopaminergic neuronal conversion from adult rat skeletal muscle-derived stem cells in vitro. Neurochemical research. vol 37. issue 9. 2012-11-20. PMID:22723079. |
subsequently, these neurosphere-like cell clusters were further directed to dopaminergic differentiation through two major induction steps, patterning to midbrain progenitors with sonic hedgehog and fibroblast growth factor 8, followed by the differentiation to dopaminergic neurons with neurotrophic factors (glial cell line-derived neurotrophic factor) and chemicals (ascorbic acid, forskolin). |
2012-11-20 |
2023-08-12 |
rat |
| Kosuke Hamaguchi, Richard Moone. Recurrent interactions between the input and output of a songbird cortico-basal ganglia pathway are implicated in vocal sequence variability. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 34. 2012-11-19. PMID:22915110. |
these experiments indicate that activity travels to hvc through at least two independent ipsilateral pathways, one of which involves fast signaling through a midbrain dopaminergic cell group, reminiscent of recurrent mesocortical loops described in mammals. |
2012-11-19 |
2023-08-12 |
Not clear |
| Laia Lladó-Pelfort, Noemí Santana, Valentina Ghisi, Francesc Artigas, Pau Celad. 5-HT1A receptor agonists enhance pyramidal cell firing in prefrontal cortex through a preferential action on GABA interneurons. Cerebral cortex (New York, N.Y. : 1991). vol 22. issue 7. 2012-11-13. PMID:21893679. |
this results in pyramidal disinhibition and subsequent downstream excitations of subcortical structures reciprocally connected with pfc, such as midbrain dopaminergic neurons. |
2012-11-13 |
2023-08-12 |
rat |