| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Douglas S Richardson, David M Rodrigues, Brandy D Hyndman, Mathieu J F Crupi, Adrian C Nicolescu, Lois M Mulliga. Alternative splicing results in RET isoforms with distinct trafficking properties. Molecular biology of the cell. vol 23. issue 19. 2013-02-19. PMID:22875993. |
ret encodes a receptor tyrosine kinase that is essential for spermatogenesis, development of the sensory, sympathetic, parasympathetic, and enteric nervous systems and the kidneys, as well as for maintenance of adult midbrain dopaminergic neurons. |
2013-02-19 |
2023-08-12 |
Not clear |
| Wei-Xing Pan, Jennifer Brown, Joshua Tate Dudma. Neural signals of extinction in the inhibitory microcircuit of the ventral midbrain. Nature neuroscience. vol 16. issue 1. 2013-02-19. PMID:23222913. |
midbrain dopaminergic (da) neurons are thought to guide learning via phasic elevations of firing in response to reward predicting stimuli. |
2013-02-19 |
2023-08-12 |
mouse |
| Sijie Tan, Wai Ping Lam, Maria S M Wai, Wan-Hua Amy Yu, David T Ye. Chronic ketamine administration modulates midbrain dopamine system in mice. PloS one. vol 7. issue 8. 2013-02-12. PMID:22937133. |
activation of midbrain dopaminergic neurons could be related to ketamine modulated cortical-subcortical glutamate connections. |
2013-02-12 |
2023-08-12 |
mouse |
| S Barak, S Ahmadiantehrani, V Kharazia, D Ro. Positive autoregulation of GDNF levels in the ventral tegmental area mediates long-lasting inhibition of excessive alcohol consumption. Translational psychiatry. vol 1. 2013-02-11. PMID:22238721. |
glial cell line-derived neurotrophic factor (gdnf) is an essential growth factor for the survival and maintenance of the midbrain dopaminergic (da-ergic) neurons. |
2013-02-11 |
2023-08-12 |
rat |
| Shan-shan Wang, Chun-ling Wei, Zhi-qiang Liu, Wei Re. [The influence of L-glutamate and carbachol on burst firing of dopaminergic neurons in ventral tegmental area]. Sheng li xue bao : [Acta physiologica Sinica]. vol 63. issue 1. 2013-01-31. PMID:21340431. |
this experiment investigated the burst firing of vta dopaminergic neurons in rat midbrain slices perfused with carbachol and l-glutamate individually or simultaneously to understand the neurotransmitter mechanism underlying burst generation. |
2013-01-31 |
2023-08-12 |
rat |
| Olivier Pauly, Seyed-Ahmad Ahmadi, Annika Plate, Kai Boetzel, Nassir Nava. Detection of substantia nigra echogenicities in 3D transcranial ultrasound for early diagnosis of Parkinson disease. Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. vol 15. issue Pt 3. 2013-01-29. PMID:23286161. |
parkinson's disease (pd) is a neurodegenerative movement disorder caused by decay of dopaminergic cells in the substantia nigra (sn), which are basal ganglia residing within the midbrain area. |
2013-01-29 |
2023-08-12 |
Not clear |
| Emília P Duarte, Michele Curcio, Lorella M Canzoniero, Carlos B Duart. Neuroprotection by GDNF in the ischemic brain. Growth factors (Chur, Switzerland). vol 30. issue 4. 2013-01-25. PMID:22670840. |
the glial cell line-derived neurotrophic factor (gdnf) was first identified as a survival factor for midbrain dopaminergic neurons, but additional studies provided evidences for a role as a trophic factor for other neurons of the central and peripheral nervous systems. |
2013-01-25 |
2023-08-12 |
Not clear |
| Fang Wang, Heng Zhai, Luqi Huang, Hui Li, Yan Xu, Xian Qiao, Shenggang Sun, Yan W. Aspirin protects dopaminergic neurons against lipopolysaccharide-induced neurotoxicity in primary midbrain cultures. Journal of molecular neuroscience : MN. vol 46. issue 1. 2013-01-24. PMID:21584653. |
aspirin protects dopaminergic neurons against lipopolysaccharide-induced neurotoxicity in primary midbrain cultures. |
2013-01-24 |
2023-08-12 |
Not clear |
| Sangram S Parelkar, Juan G Cadena, Chul Kim, Zhaohui Wang, Rachel Sugal, Brooke Bentley, Luis Moral, Helen C Ardley, Lawrence M Schwart. The parkin-like human homolog of Drosophila ariadne-1 (HHARI) can induce aggresome formation in mammalian cells and is immunologically detectable in Lewy bodies. Journal of molecular neuroscience : MN. vol 46. issue 1. 2013-01-24. PMID:21590270. |
loss of functional parkin is responsible for the death of midbrain dopaminergic neurons in human autosomal recessive juvenile parkinsonism. |
2013-01-24 |
2023-08-12 |
human |
| M Maral Mouradia. MicroRNAs in Parkinson's disease. Neurobiology of disease. vol 46. issue 2. 2013-01-24. PMID:22245218. |
in midbrain dopaminergic neurons, which degenerate in parkinson's disease (pd) causing motor signs and symptoms, disruption of this network results in their progressive loss associated with impaired motor activity in drosophila and mouse models. |
2013-01-24 |
2023-08-12 |
mouse |
| Anne-Marike Schiffer, Christiane Ahlheim, Moritz F Wurm, Ricarda I Schubot. Surprised at all the entropy: hippocampal, caudate and midbrain contributions to learning from prediction errors. PloS one. vol 7. issue 5. 2013-01-24. PMID:22570715. |
the present fmri study used an action-observation paradigm to investigate the contributions of the hippocampus, caudate nucleus and midbrain dopaminergic system to different types of learning: learning in the absence of prediction errors, learning from prediction errors, and responding to the accumulation of prediction errors in unpredictable stimulus configurations. |
2013-01-24 |
2023-08-12 |
Not clear |
| Anne-Marike Schiffer, Christiane Ahlheim, Moritz F Wurm, Ricarda I Schubot. Surprised at all the entropy: hippocampal, caudate and midbrain contributions to learning from prediction errors. PloS one. vol 7. issue 5. 2013-01-24. PMID:22570715. |
in sum, we established that the midbrain dopaminergic system, the hippocampus, and the caudate nucleus were to different degrees significantly involved in the three different types of learning: acquisition of new information, learning from prediction errors and responding to unpredictable stimulus developments. |
2013-01-24 |
2023-08-12 |
Not clear |
| Christine Esslinger, Susanne Englisch, Dragos Inta, Franziska Rausch, Frederike Schirmbeck, Daniela Mier, Peter Kirsch, Andreas Meyer-Lindenberg, Mathias Zin. Ventral striatal activation during attribution of stimulus saliency and reward anticipation is correlated in unmedicated first episode schizophrenia patients. Schizophrenia research. vol 140. issue 1-3. 2013-01-18. PMID:22784688. |
several functional magnetic resonance imaging (fmri) investigations revealed neurobiological correlates of these deficits, raising the hypothesis of a common basis in midbrain dopaminergic signaling. |
2013-01-18 |
2023-08-12 |
human |
| Marcel M Daadi, Brad A Grueter, Robert C Malenka, D Eugene Redmond, Gary K Steinber. Dopaminergic neurons from midbrain-specified human embryonic stem cell-derived neural stem cells engrafted in a monkey model of Parkinson's disease. PloS one. vol 7. issue 7. 2013-01-16. PMID:22815935. |
parkinson's disease (pd) is a neurological disorder characterized by the loss of midbrain dopaminergic (da) neurons. |
2013-01-16 |
2023-08-12 |
human |
| Wen-Liang Zhou, Srdjan D Anti. Rapid dopaminergic and GABAergic modulation of calcium and voltage transients in dendrites of prefrontal cortex pyramidal neurons. The Journal of physiology. vol 590. issue 16. 2013-01-08. PMID:22641784. |
the spatio-temporal pattern of dendritic calcium suppression described in this paper is expected to occur during phasic dopaminergic signalling, when midbrain dopaminergic neurons generate a transient (0.5 s) burst of aps in response to a salient event. |
2013-01-08 |
2023-08-12 |
Not clear |
| Anne K Meyer, Alexander Jarosch, Katja Schurig, Ina Nuesslein, Stefan Kißenkötter, Alexander Storc. Fetal mouse mesencephalic NPCs generate dopaminergic neurons from post-mitotic precursors and maintain long-term neural but not dopaminergic potential in vitro. Brain research. vol 1474. 2013-01-08. PMID:22842082. |
we investigated the proliferative behavior and dopaminergic differentiation capacity of fetal mouse midbrain npcs derived from e10 to e14 embryos expanded either as neurosphere or monolayer culture. |
2013-01-08 |
2023-08-12 |
mouse |
| Anne K Meyer, Alexander Jarosch, Katja Schurig, Ina Nuesslein, Stefan Kißenkötter, Alexander Storc. Fetal mouse mesencephalic NPCs generate dopaminergic neurons from post-mitotic precursors and maintain long-term neural but not dopaminergic potential in vitro. Brain research. vol 1474. 2013-01-08. PMID:22842082. |
we did not find dopaminergic differentiation in long-term expanded mouse npc types, which is in contrast to rat and human fetal midbrain npcs. |
2013-01-08 |
2023-08-12 |
mouse |
| Heike Stockner, Petra Schwingenschuh, Atbin Djamshidian, Laura Silveira-Moriyama, Petra Katschnig, Klaus Seppi, John Dickson, Mark J Edwards, Andrew J Lees, Werner Poewe, Kailash P Bhati. Is transcranial sonography useful to distinguish scans without evidence of dopaminergic deficit patients from Parkinson's disease? Movement disorders : official journal of the Movement Disorder Society. vol 27. issue 9. 2012-12-17. PMID:22744819. |
the aim of this study was to investigate the prevalence of midbrain hyperechogenicity in patients with suspected parkinsonism and scans without evidence of dopaminergic deficit (swedd), in comparison to pd patients. |
2012-12-17 |
2023-08-12 |
Not clear |
| Changgeng Peng, Na Li, Yen-Kar Ng, Jingzhong Zhang, Florian Meier, Fabian J Theis, Matthias Merkenschlager, Wei Chen, Wolfgang Wurst, Nilima Prakas. A unilateral negative feedback loop between miR-200 microRNAs and Sox2/E2F3 controls neural progenitor cell-cycle exit and differentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 38. 2012-12-03. PMID:22993445. |
we show that the mir-200 family plays a crucial role for the proper generation and survival of ventral neuronal populations in the murine midbrain/hindbrain region, including midbrain dopaminergic neurons, by directly targeting the pluripotency factor sox2 and the cell-cycle regulator e2f3 in neural stem/progenitor cells. |
2012-12-03 |
2023-08-12 |
mouse |
| Ayse Ulusoy, Tomas Björklund, Kerstin Buck, Deniz Kiri. Dysregulated dopamine storage increases the vulnerability to α-synuclein in nigral neurons. Neurobiology of disease. vol 47. issue 3. 2012-11-29. PMID:22659302. |
impairments in the capacity of dopaminergic neurons to handle cytoplasmic dopamine may be a critical factor underlying the selective vulnerability of midbrain dopamine neurons in parkinson's disease. |
2012-11-29 |
2023-08-12 |
mouse |