| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christian M Nefzger, Colin T Su, Stewart A Fabb, Brigham J Hartley, Siew J Beh, Wendy R Zeng, John M Haynes, Colin W Pouto. Lmx1a allows context-specific isolation of progenitors of GABAergic or dopaminergic neurons during neural differentiation of embryonic stem cells. Stem cells (Dayton, Ohio). vol 30. issue 7. 2012-10-19. PMID:22495882. |
the majority of these cells did not express the ventral midbrain dopaminergic marker foxa2 or dorsal roof plate marker bmp-2. |
2012-10-19 |
2023-08-12 |
mouse |
| M Foster Oliv. Ethanol, glutamate, and the ventral tegmental area--a commentary on: Ding, Engleman, Rodd, and McBride, "ethanol increases glutamate neurotransmission in the posterior ventral tegmental area of female wistar rats". Alcoholism, clinical and experimental research. vol 36. issue 6. 2012-10-18. PMID:22510109. |
these findings have important implications for interactions between glutamatergic and dopaminergic mediation of alcohol reinforcement in the ventral midbrain. |
2012-10-18 |
2023-08-12 |
rat |
| Sara Cipriani, Cody A Desjardins, Thomas C Burdett, Yuehang Xu, Kui Xu, Michael A Schwarzschil. Urate and its transgenic depletion modulate neuronal vulnerability in a cellular model of Parkinson's disease. PloS one. vol 7. issue 5. 2012-10-16. PMID:22606360. |
in this study we investigated the effects of modulating intracellular urate concentration on 1-methyl-4-phenyl-pyridinium (mpp(+))-induced degeneration of dopaminergic neurons in cultures of mouse ventral mesencephalon prepared to contain low (neuron-enriched cultures) or high (neuron-glial cultures) percentage of astrocytes. |
2012-10-16 |
2023-08-12 |
mouse |
| Roy D Bayly, Charmaine Y Brown, Seema Agarwal. A novel role for FOXA2 and SHH in organizing midbrain signaling centers. Developmental biology. vol 369. issue 1. 2012-10-16. PMID:22750257. |
the recent identification of midbrain fp as a source of dopaminergic neurons has renewed interest in its specification and organization, which remain poorly understood. |
2012-10-16 |
2023-08-12 |
chicken |
| Heather N Lavezzi, Kenneth P Parsley, Daniel S Zah. Mesopontine rostromedial tegmental nucleus neurons projecting to the dorsal raphe and pedunculopontine tegmental nucleus: psychostimulant-elicited Fos expression and collateralization. Brain structure & function. vol 217. issue 3. 2012-10-15. PMID:22179106. |
the mesopontine rostromedial tegmental nucleus (rmtg) is a gabaergic structure in the ventral midbrain and rostral pons that, when activated, inhibits dopaminergic neurons in the ventral tegmental area and substantia nigra compacta. |
2012-10-15 |
2023-08-12 |
Not clear |
| Anju Vasudevan, Chungkil Won, Suyan Li, Ferenc Erdélyi, Gábor Szabó, Kwang-Soo Ki. Dopaminergic neurons modulate GABA neuron migration in the embryonic midbrain. Development (Cambridge, England). vol 139. issue 17. 2012-10-15. PMID:22872083. |
dopaminergic neurons modulate gaba neuron migration in the embryonic midbrain. |
2012-10-15 |
2023-08-12 |
mouse |
| Anju Vasudevan, Chungkil Won, Suyan Li, Ferenc Erdélyi, Gábor Szabó, Kwang-Soo Ki. Dopaminergic neurons modulate GABA neuron migration in the embryonic midbrain. Development (Cambridge, England). vol 139. issue 17. 2012-10-15. PMID:22872083. |
neuronal migration, a key event during brain development, remains largely unexplored in the mesencephalon, where dopaminergic (da) and gaba neurons constitute two major neuronal populations. |
2012-10-15 |
2023-08-12 |
mouse |
| Indrani Datta, Ramesh Bhond. Can mesenchymal stem cells reduce vulnerability of dopaminergic neurons in the substantia nigra to oxidative insult in individuals at risk to Parkinson's disease? Cell biology international. vol 36. issue 7. 2012-10-11. PMID:22417707. |
pd (parkinson's disease) is characterized by the selective loss of da (dopaminergic) neurons in the substantia nigra of the midbrain region, but not in the ventral tegmental area and other catecholaminergic cell group areas. |
2012-10-11 |
2023-08-12 |
Not clear |
| A Parent, M Parent, A Charar. Glutamatergic inputs to midbrain dopaminergic neurons in primates. Parkinsonism & related disorders. vol 5. issue 4. 2012-10-02. PMID:18591140. |
glutamatergic inputs to midbrain dopaminergic neurons in primates. |
2012-10-02 |
2023-08-12 |
squirrel_monkey |
| A Parent, M Parent, A Charar. Glutamatergic inputs to midbrain dopaminergic neurons in primates. Parkinsonism & related disorders. vol 5. issue 4. 2012-10-02. PMID:18591140. |
anterograde tract-tracing and immunohistochemical methods were used to study projections from the pedunculopontine tegmental nucleus (ppn) to midbrain dopaminergic neurons in the squirrel monkey (saimiri sciureus). |
2012-10-02 |
2023-08-12 |
squirrel_monkey |
| C Fernández, K De La Cuétara, O Castellanos, O González, N Nunez, L Alvarez, R Macías, A Torres, R Pernas, J Soto, H Molina, W Sole. Brain aging and neurotransplantation. I. Nigral cell suspension graft to aged rodent striatum and motor disabilities. Archives of gerontology and geriatrics. vol 19 Suppl 1. 2012-10-02. PMID:18649843. |
deficient rats were divided in two groups: one group received dissociated fetal dopaminergic cells from ventral mesencephalon (e12-e14) to striatum, whereas the other group having the same level of impairment, was followed without any graft and served as age-matched controls. |
2012-10-02 |
2023-08-12 |
rat |
| Kambiz N Alavian, Horst H Simo. Linkage of cDNA expression profiles of mesencephalic dopaminergic neurons to a genome-wide in situ hybridization database. Molecular neurodegeneration. vol 4. 2012-10-02. PMID:19178742. |
midbrain dopaminergic neurons are involved in control of emotion, motivation and motor behavior. |
2012-10-02 |
2023-08-12 |
Not clear |
| Kambiz N Alavian, Horst H Simo. Linkage of cDNA expression profiles of mesencephalic dopaminergic neurons to a genome-wide in situ hybridization database. Molecular neurodegeneration. vol 4. 2012-10-02. PMID:19178742. |
several groups have looked at the molecular identity of midbrain dopaminergic neurons and have suggested the gene expression profile of these neurons. |
2012-10-02 |
2023-08-12 |
Not clear |
| C M Gall, S J Gold, P J Isackson, K B Seroog. Brain-derived neurotrophic factor and neurotrophin-3 mRNAs are expressed in ventral midbrain regions containing dopaminergic neurons. Molecular and cellular neurosciences. vol 3. issue 1. 2012-10-02. PMID:19912846. |
brain-derived neurotrophic factor and neurotrophin-3 mrnas are expressed in ventral midbrain regions containing dopaminergic neurons. |
2012-10-02 |
2023-08-12 |
rat |
| C M Gall, S J Gold, P J Isackson, K B Seroog. Brain-derived neurotrophic factor and neurotrophin-3 mRNAs are expressed in ventral midbrain regions containing dopaminergic neurons. Molecular and cellular neurosciences. vol 3. issue 1. 2012-10-02. PMID:19912846. |
in this study, cellular distributions of mrnas for the nerve growth factor (ngf) family of neurotrophins (ngf, bdnf, and nt-3) and the catecholamine biosynthetic enzyme tyrosine hydroxylase (th) were evaluated in the ventral mesencephalon of adult rat to determine if the neurotrophins are synthesized in regions of the responsive dopaminergic cells. |
2012-10-02 |
2023-08-12 |
rat |
| T Kuriyama, J Taguchi, K Kuriyam. Functional alterations in striatal cholinergic and striato-nigral gabaergic neurons following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration. Neurochemistry international. vol 16. issue 3. 2012-10-02. PMID:20504575. |
neurochemical changes in cholinergic neurons in the striatum and ?-aminobutyric acid (gaba)ergic neurons in the midbrain, especially in the basal ganglia, have been examined following the intraperitoneal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp), which is known to cause behavioral changes resembling those in parkinson's disease due to the destruction of nigro-striatal dopaminergic neurons. |
2012-10-02 |
2023-08-12 |
mouse |
| Yasushi Takagi, Jun Takahash. Primate embryonic stem cells as a source of dopaminergic neurons: A novel transplantation for Parkinson's disease. Discovery medicine. vol 5. issue 26. 2012-10-02. PMID:20704914. |
extract: the most common neurodegenerative movement disorder in man is parkinson's disease (pd) and it is characterized by the loss of midbrain dopaminergic neurons in the substantia nigra of the brain. |
2012-10-02 |
2023-08-12 |
Not clear |
| Efstathia Kitsou, Sheng Pan, Jianpeng Zhang, Min Shi, Aram Zabeti, Dennis W Dickson, Roger Albin, Marla Gearing, Daniel T Kashima, Yan Wang, Richard P Beyer, Yong Zhou, Catherine Pan, W Michael Caudle, Jing Zhan. Identification of proteins in human substantia nigra. Proteomics. Clinical applications. vol 2. issue 5. 2012-10-02. PMID:21136874. |
while examination of the human cortex has provided some insight, very little is known about the proteome of the human midbrain, which demonstrates substantial loss of dopaminergic neurons in the substantia nigra pars compacta (snpc) in parkinson's disease (pd). |
2012-10-02 |
2023-08-12 |
human |
| M Ząbek, W Mazurowski, J Dymecki, J Stelmachów, E Zawad. A long term follow-up of fetal dopaminergic neurons transplantation into the brain of three parkinsonian patients. Restorative neurology and neuroscience. vol 6. issue 2. 2012-10-02. PMID:21551736. |
in three parkinsonian patients ages 48, 53, and 50, human fetal dopaminergic cells taken from the ventral part of mesencephalon of 11-12-week-old fetuses were implanted into the head of caudate nucleus. |
2012-10-02 |
2023-08-12 |
human |
| W M van Roon, J C Copray, R I Hogenesch, I Kema, E M Meyer, G Molenaar, C Lugard, M J Staal, K G G. Fetal porcine ventral mesencephalon grafts: dissection procedure and cellular characterization in culture. Restorative neurology and neuroscience. vol 7. issue 4. 2012-10-02. PMID:21551790. |
the objective of this study was to develop an optimal dissection procedure for fetal porcine ventral mesencephalon (vm) grafts and to characterize the cellular composition of such an explant, in particular with respect to the dopaminergic and gabaergic components. |
2012-10-02 |
2023-08-12 |
human |