| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hidenori Aizawa, Ryunosuke Amo, Hitoshi Okamot. Phylogeny and ontogeny of the habenular structure. Frontiers in neuroscience. vol 5. 2012-10-02. PMID:22203792. |
habenula is an epithalamic nucleus connecting the forebrain with the ventral midbrain and hindbrain that plays a pivotal role in decision making by regulating dopaminergic and serotonergic activities. |
2012-10-02 |
2023-08-12 |
human |
| Diana C Ferrari, Baya J Mdzomba, Nathalie Dehorter, Catherine Lopez, François J Michel, Frédéric Libersat, Constance Hammon. Midbrain dopaminergic neurons generate calcium and sodium currents and release dopamine in the striatum of pups. Frontiers in cellular neuroscience. vol 6. 2012-10-02. PMID:22408606. |
midbrain dopaminergic neurons generate calcium and sodium currents and release dopamine in the striatum of pups. |
2012-10-02 |
2023-08-12 |
mouse |
| Diana C Ferrari, Baya J Mdzomba, Nathalie Dehorter, Catherine Lopez, François J Michel, Frédéric Libersat, Constance Hammon. Midbrain dopaminergic neurons generate calcium and sodium currents and release dopamine in the striatum of pups. Frontiers in cellular neuroscience. vol 6. 2012-10-02. PMID:22408606. |
midbrain dopaminergic neurons (mda neurons) are essential for the control of diverse motor and cognitive behaviors. |
2012-10-02 |
2023-08-12 |
mouse |
| K Richard Ridderinkhof, Nelleke C van Wouwe, Guido P H Band, Scott A Wylie, Stefan Van der Stigchel, Pieter van Hees, Jessika Buitenweg, Irene van de Vijver, Wery P M van den Wildenber. A tribute to charlie chaplin: induced positive affect improves reward-based decision-learning in Parkinson's disease. Frontiers in psychology. vol 3. 2012-10-02. PMID:22707944. |
we hypothesized that such decision-learning deficits are alleviated by induced positive affect, which is thought to incur transient boosts in midbrain and striatal dopaminergic activity. |
2012-10-02 |
2023-08-12 |
Not clear |
| George Stoica, Gina Lungu, Nicole L Bjorklund, Giulio Taglialatela, Xing Zhang, Veronica Chiu, Herbert H Hill, James O Schenk, Ian Murra. Potential role of α-synuclein in neurodegeneration: studies in a rat animal model. Journal of neurochemistry. vol 122. issue 4. 2012-09-27. PMID:22639889. |
these rats demonstrate progressive increases in α-syn in the brain mesencephalon followed by loss of dopaminergic terminals in the basal ganglia (bg) and motor impairments. |
2012-09-27 |
2023-08-12 |
human |
| Stanislav Koulchitsky, Benjamin De Backer, Etienne Quertemont, Corinne Charlier, Vincent Seuti. Differential effects of cocaine on dopamine neuron firing in awake and anesthetized rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 7. 2012-09-21. PMID:22298123. |
we investigated the effects of cocaine on the firing of midbrain dopaminergic (da) neurons, both in anesthetized and awake rats, using pre-implanted multielectrode arrays and a recently developed telemetric recording system. |
2012-09-21 |
2023-08-12 |
rat |
| Yeun Su Choo, Georg Vogler, Danling Wang, Sreehari Kalvakuri, Anton Iliuk, W Andy Tao, Rolf Bodmer, Zhuohua Zhan. Regulation of parkin and PINK1 by neddylation. Human molecular genetics. vol 21. issue 11. 2012-09-21. PMID:22388932. |
nedd8 immunoreactivity is associated with lewy bodies in midbrain dopaminergic neurons of pd patients. |
2012-09-21 |
2023-08-12 |
drosophila_melanogaster |
| Sushruta Koppula, Hemant Kumar, In Su Kim, Dong-Kug Cho. Reactive oxygen species and inhibitors of inflammatory enzymes, NADPH oxidase, and iNOS in experimental models of Parkinson's disease. Mediators of inflammation. vol 2012. 2012-09-20. PMID:22577256. |
mounting evidence suggests that activation of nadph oxidase and the expression of inos are directly linked to the generation of highly reactive ros which affects various cellular components and preferentially damage midbrain dopaminergic neurons in pd. |
2012-09-20 |
2023-08-12 |
Not clear |
| Xian Lin, Loukia Parisiadou, Carmelo Sgobio, Guoxiang Liu, Jia Yu, Lixin Sun, Hoon Shim, Xing-Long Gu, Jing Luo, Cai-Xia Long, Jinhui Ding, Yolanda Mateo, Patricia H Sullivan, Ling-Gang Wu, David S Goldstein, David Lovinger, Huaibin Ca. Conditional expression of Parkinson's disease-related mutant α-synuclein in the midbrain dopaminergic neurons causes progressive neurodegeneration and degradation of transcription factor nuclear receptor related 1. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 27. 2012-09-18. PMID:22764233. |
conditional expression of parkinson's disease-related mutant α-synuclein in the midbrain dopaminergic neurons causes progressive neurodegeneration and degradation of transcription factor nuclear receptor related 1. |
2012-09-18 |
2023-08-12 |
mouse |
| Xian Lin, Loukia Parisiadou, Carmelo Sgobio, Guoxiang Liu, Jia Yu, Lixin Sun, Hoon Shim, Xing-Long Gu, Jing Luo, Cai-Xia Long, Jinhui Ding, Yolanda Mateo, Patricia H Sullivan, Ling-Gang Wu, David S Goldstein, David Lovinger, Huaibin Ca. Conditional expression of Parkinson's disease-related mutant α-synuclein in the midbrain dopaminergic neurons causes progressive neurodegeneration and degradation of transcription factor nuclear receptor related 1. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 27. 2012-09-18. PMID:22764233. |
α-synuclein (α-syn) plays a prominent role in the degeneration of midbrain dopaminergic (mda) neurons in parkinson's disease (pd). |
2012-09-18 |
2023-08-12 |
mouse |
| Nico Bunzeck, Christian F Doeller, Ray J Dolan, Emrah Duze. Contextual interaction between novelty and reward processing within the mesolimbic system. Human brain mapping. vol 33. issue 6. 2012-09-17. PMID:21520353. |
medial temporal lobe (mtl) dependent long-term memory for novel events is modulated by a circuitry that also responds to reward and includes the ventral striatum, dopaminergic midbrain, and medial orbitofrontal cortex (mofc). |
2012-09-17 |
2023-08-12 |
Not clear |
| H Liu, L Wei, Q Tao, H Deng, M Ming, P Xu, W L. Decreased NURR1 and PITX3 gene expression in Chinese patients with Parkinson's disease. European journal of neurology. vol 19. issue 6. 2012-09-14. PMID:22309633. |
the preferential degeneration of midbrain dopaminergic (mda) neurons in the substantia nigra pars compacta is the pathological hallmark in parkinson's disease (pd). |
2012-09-14 |
2023-08-12 |
Not clear |
| Garrett E Alexande. Biology of Parkinson's disease: pathogenesis and pathophysiology of a multisystem neurodegenerative disorder. Dialogues in clinical neuroscience. vol 6. issue 3. 2012-09-10. PMID:22033559. |
the characteristic motor impairments - bradykinesia, rigidity, and resting tremor - result from degenerative loss of midbrain dopamine (da) neurons in the substantia nigra, and are responsive to symptomatic treatment with dopaminergic medications and functional neurosurgery. |
2012-09-10 |
2023-08-12 |
human |
| Vishnu P Murty, Kevin S Labar, R Alison Adcoc. Threat of punishment motivates memory encoding via amygdala, not midbrain, interactions with the medial temporal lobe. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 26. 2012-09-10. PMID:22745496. |
of note, punishment-motivated learning was not associated with activation of dopaminergic midbrain, as would be predicted by valence-independent models of motivation to learn. |
2012-09-10 |
2023-08-12 |
human |
| Emmanouil Metzakopian, Wei Lin, Mali Salmon-Divon, Heidi Dvinge, Elisabet Andersson, Johan Ericson, Thomas Perlmann, Jeffrey A Whitsett, Paul Bertone, Siew-Lan An. Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors. Development (Cambridge, England). vol 139. issue 14. 2012-09-04. PMID:22696295. |
genome-wide characterization of foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors. |
2012-09-04 |
2023-08-12 |
mouse |
| Emmanouil Metzakopian, Wei Lin, Mali Salmon-Divon, Heidi Dvinge, Elisabet Andersson, Johan Ericson, Thomas Perlmann, Jeffrey A Whitsett, Paul Bertone, Siew-Lan An. Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors. Development (Cambridge, England). vol 139. issue 14. 2012-09-04. PMID:22696295. |
the transcription factors foxa1 and foxa2 promote the specification of midbrain dopaminergic (mda) neurons and the floor plate. |
2012-09-04 |
2023-08-12 |
mouse |
| Thomas J Whitford, Judith M Ford, Daniel H Mathalon, Marek Kubicki, Martha E Shento. Schizophrenia, myelination, and delayed corollary discharges: a hypothesis. Schizophrenia bulletin. vol 38. issue 3. 2012-08-30. PMID:20855415. |
on a neurophysiological level, this prediction error leads to the increased activity of dopaminergic neurons in the midbrain. |
2012-08-30 |
2023-08-12 |
Not clear |
| Jeong Won Jahng, Sang Bae Yoo, Jin Young Kim, Bom-Taeck Kim, Jong-Ho Le. Increased mesohippocampal dopaminergic activity and improved depression-like behaviors in maternally separated rats following repeated fasting/refeeding cycles. Journal of obesity. vol 2012. 2012-08-30. PMID:22934157. |
fasting/refeeding cycles increased dopamine levels not only in the hippocampus but also in the midbrain dopaminergic neurons in ms rats, but not in nh controls. |
2012-08-30 |
2023-08-12 |
rat |
| Bradley Watmuff, Colin W Pouton, John M Hayne. In vitro maturation of dopaminergic neurons derived from mouse embryonic stem cells: implications for transplantation. PloS one. vol 7. issue 2. 2012-08-27. PMID:22384125. |
embryonic stem cell-derived neural progenitor or precursor cells, adult neurons and fetal midbrain tissue have all been used to replace dying dopaminergic neurons. |
2012-08-27 |
2023-08-12 |
mouse |
| Bradley Watmuff, Colin W Pouton, John M Hayne. In vitro maturation of dopaminergic neurons derived from mouse embryonic stem cells: implications for transplantation. PloS one. vol 7. issue 2. 2012-08-27. PMID:22384125. |
at day 13 of differentiation a three hour exposure to gaba (30 µm) or l-glutamate (30 µm) increased the number of midbrain dopaminergic (th(+) and pitx3(+)) neurons labeled with the membrane-impermeable nuclear dye topro-3. |
2012-08-27 |
2023-08-12 |
mouse |