| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Despina Kokona, Nadia Schneider, Helena Giannakaki-Zimmermann, Joel Jovanovic, Andreas Ebneter, Martin Zinkernage. Noninvasive Quantification of Retinal Microglia Using Widefield Autofluorescence Imaging. Investigative ophthalmology & visual science. vol 58. issue 4. 2017-06-26. PMID:28395300. |
to validate widefield autofluorescence (af) in vivo imaging of the retina in mice expressing green fluorescent protein (gfp) in microglia, and to monitor retinal microglia reconstitution in vivo after lethal irradiation and bone marrow transplantation. |
2017-06-26 |
2023-08-13 |
mouse |
| Dana K Merriman, Benjamin S Sajdak, Wei Li, Bryan W Jone. Seasonal and post-trauma remodeling in cone-dominant ground squirrel retina. Experimental eye research. vol 150. 2017-06-15. PMID:26808487. |
while the ground squirrel retina is understandably prominent in the cone biochemistry, physiology, and circuitry literature, far less is known about the remodeling potential of its retinal pigment epithelium, neurons, macroglia, or microglia. |
2017-06-15 |
2023-08-13 |
human |
| S Kuehn, J Hurst, F Rensinghoff, T Tsai, S Grauthoff, Y Satgunarajah, H B Dick, S Schnichels, S C Joachi. Degenerative effects of cobalt-chloride treatment on neurons and microglia in a porcine retina organ culture model. Experimental eye research. vol 155. 2017-06-15. PMID:28089775. |
degenerative effects of cobalt-chloride treatment on neurons and microglia in a porcine retina organ culture model. |
2017-06-15 |
2023-08-13 |
Not clear |
| Ajay Kumar, Shailendra Giri, Ashok Kuma. 5-Aminoimidazole-4-carboxamide ribonucleoside-mediated adenosine monophosphate-activated protein kinase activation induces protective innate responses in bacterial endophthalmitis. Cellular microbiology. vol 18. issue 12. 2017-05-18. PMID:27264993. |
aicar also reduced the expression of sa-induced glycolytic genes, including hexokinase 2 and glucose transporter 1 in microglia, bone marrow-derived macrophages and the mouse retina. |
2017-05-18 |
2023-08-13 |
mouse |
| Yudong Zhang, Bo Peng, Shuihua Wang, Yu-Xiang Liang, Jiquan Yang, Kwok-Fai So, Ti-Fei Yua. Image processing methods to elucidate spatial characteristics of retinal microglia after optic nerve transection. Scientific reports. vol 6. 2017-02-03. PMID:26888347. |
in optical nerve transection model of the retina, the retrograde degeneration of retinal ganglion cells induces microglial activations to a unique morphology termed rod microglia. |
2017-02-03 |
2023-08-13 |
Not clear |
| Yudong Zhang, Bo Peng, Shuihua Wang, Yu-Xiang Liang, Jiquan Yang, Kwok-Fai So, Ti-Fei Yua. Image processing methods to elucidate spatial characteristics of retinal microglia after optic nerve transection. Scientific reports. vol 6. 2017-02-03. PMID:26888347. |
a few studies described the rod microglia in the cortex and retina; however, the spatial characteristic of rod microglia is not fully understood. |
2017-02-03 |
2023-08-13 |
Not clear |
| E G O'Koren, R Mathew, D R Saba. Fate mapping reveals that microglia and recruited monocyte-derived macrophages are definitively distinguishable by phenotype in the retina. Scientific reports. vol 6. 2016-12-27. PMID:26856416. |
fate mapping reveals that microglia and recruited monocyte-derived macrophages are definitively distinguishable by phenotype in the retina. |
2016-12-27 |
2023-08-13 |
Not clear |
| E G O'Koren, R Mathew, D R Saba. Fate mapping reveals that microglia and recruited monocyte-derived macrophages are definitively distinguishable by phenotype in the retina. Scientific reports. vol 6. 2016-12-27. PMID:26856416. |
the recent paradigm shift that microglia are yolk sac-derived, not hematopoietic-derived, is reshaping our knowledge about the isolated role of microglia in cns diseases, including degenerative conditions of the retina. |
2016-12-27 |
2023-08-13 |
Not clear |
| E G O'Koren, R Mathew, D R Saba. Fate mapping reveals that microglia and recruited monocyte-derived macrophages are definitively distinguishable by phenotype in the retina. Scientific reports. vol 6. 2016-12-27. PMID:26856416. |
the literature contains conflicting observations about whether microglia, including in the retina, increase expression of these markers in neuroinflammation. |
2016-12-27 |
2023-08-13 |
Not clear |
| Caitlin E Mac Nair, Cassandra L Schlamp, Angela D Montgomery, Valery I Shestopalov, Robert W Nickell. Retinal glial responses to optic nerve crush are attenuated in Bax-deficient mice and modulated by purinergic signaling pathways. Journal of neuroinflammation. vol 13. issue 1. 2016-12-19. PMID:27126275. |
since the eye is immune privileged, innate immune functions are the responsibility of the glia, specifically the microglia, astrocytes, and müller cells that populate the retina. |
2016-12-19 |
2023-08-13 |
mouse |
| Elena Vecino, F David Rodriguez, Noelia Ruzafa, Xandra Pereiro, Sansar C Sharm. Glia-neuron interactions in the mammalian retina. Progress in retinal and eye research. vol 51. 2016-11-10. PMID:26113209. |
three main types of glial cells are found in the mammalian retina that serve to maintain retinal homeostasis: astrocytes, müller cells and resident microglia. |
2016-11-10 |
2023-08-13 |
Not clear |
| Elena Vecino, F David Rodriguez, Noelia Ruzafa, Xandra Pereiro, Sansar C Sharm. Glia-neuron interactions in the mammalian retina. Progress in retinal and eye research. vol 51. 2016-11-10. PMID:26113209. |
the preferential involvement of the distinct glia cells in terms of the activity in the retina is discussed, for example, while müller cells may serve as progenitors of retinal neurons, astrocytes and microglia are responsible for synaptic pruning. |
2016-11-10 |
2023-08-13 |
Not clear |
| Helen V Danesh-Meyer, Jie Zhang, Monica L Acosta, Ilva D Rupenthal, Colin R Gree. Connexin43 in retinal injury and disease. Progress in retinal and eye research. vol 51. 2016-11-10. PMID:26432657. |
connexin43 is the most ubiquitously expressed isoform of the connexin family and in the retina it is prevalent in astrocytes, müller cells, microglia, retinal pigment epithelium and endothelial cells. |
2016-11-10 |
2023-08-13 |
Not clear |
| Lucia Corso, Anna Cavallero, Debora Baroni, Patrizia Garbati, Gianfranco Prestipino, Silvia Bisti, Mario Nobile, Cristiana Picc. Saffron reduces ATP-induced retinal cytotoxicity by targeting P2X7 receptors. Purinergic signalling. vol 12. issue 1. 2016-10-31. PMID:26739703. |
in the retina, this receptor is found in both inner and outer cells including microglia modulating signaling and health of retinal cells. |
2016-10-31 |
2023-08-13 |
mouse |
| Dennis Y Tse, Parisa Lotfi, David L Simons, Marco Sardiello, Samuel M W. Electrophysiological and Histological Characterization of Rod-Cone Retinal Degeneration and Microglia Activation in a Mouse Model of Mucopolysaccharidosis Type IIIB. Scientific reports. vol 5. 2016-10-05. PMID:26607664. |
activation of microglia and neovascularization were also detected in the mps iiib retina. |
2016-10-05 |
2023-08-13 |
mouse |
| T Noro, K Namekata, A Kimura, X Guo, Y Azuchi, C Harada, T Nakano, H Tsuneoka, T Harad. Spermidine promotes retinal ganglion cell survival and optic nerve regeneration in adult mice following optic nerve injury. Cell death & disease. vol 6. 2016-09-29. PMID:25880087. |
in addition, the oni-induced expression of inducible nitric oxide synthase in the retina was inhibited with spermidine treatment, particularly in microglia. |
2016-09-29 |
2023-08-13 |
mouse |
| L P Cen, M Han, L Zhou, L Tan, J J Liang, C P Pang, M Zhan. Bilateral retinal microglial response to unilateral optic nerve transection in rats. Neuroscience. vol 311. 2016-09-13. PMID:26432953. |
after on transection, microglia density in the ipsilateral retina increased gradually from 3 days to 2 weeks, and decreased from 3 weeks to 12 weeks, along with dramatic inverted alteration of process branch points of microglia in the ganglion cell layer (gcl). |
2016-09-13 |
2023-08-13 |
rat |
| L P Cen, M Han, L Zhou, L Tan, J J Liang, C P Pang, M Zhan. Bilateral retinal microglial response to unilateral optic nerve transection in rats. Neuroscience. vol 311. 2016-09-13. PMID:26432953. |
transformation of ramified microglia into ameboid-like macrophages with few branching processes was observed in the ipsilateral retina from 1 week to 3 weeks. |
2016-09-13 |
2023-08-13 |
rat |
| L P Cen, M Han, L Zhou, L Tan, J J Liang, C P Pang, M Zhan. Bilateral retinal microglial response to unilateral optic nerve transection in rats. Neuroscience. vol 311. 2016-09-13. PMID:26432953. |
in the inner plexiform layer (ipl), cell density and morphological changes of microglia in both the ipsilateral and contralateral retina were not prominent. |
2016-09-13 |
2023-08-13 |
rat |
| Xu Wang, Lian Zhao, Jun Zhang, Robert N Fariss, Wenxin Ma, Friedrich Kretschmer, Minhua Wang, Hao Hua Qian, Tudor C Badea, Jeffrey S Diamond, Wen-Biao Gan, Jerome E Roger, Wai T Won. Requirement for Microglia for the Maintenance of Synaptic Function and Integrity in the Mature Retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 9. 2016-08-16. PMID:26937019. |
requirement for microglia for the maintenance of synaptic function and integrity in the mature retina. |
2016-08-16 |
2023-08-13 |
mouse |