All Relations between Neurodegenerative Diseases and apoptosis

Publication Sentence Publish Date Extraction Date Species
Baolu Zha. Natural antioxidants for neurodegenerative diseases. Molecular neurobiology. vol 31. issue 1-3. 2006-01-24. PMID:15953828. the author reviews the studies on the preventing effects of natural antioxidants, such as vitamins e and c, flavonoids, and polyphenols on neurodegenerative diseases, especially summarizing the results on the protective effect of ginkgo biloba extract on neuron cells, preventing effects of green tea polyphenols on apoptosis of pc12 cells (parkison's disease model), preventing effects of genestien on amyloid-beta-induced apoptosis of hippocampal neuronal cells (alzhemer's disease model), and preventing effect of crataegus flavonoids on ischemic-reperfusion damage to the brain of the mongolian gerbil (stroke model) in the laboratory. 2006-01-24 2023-08-12 Not clear
b' Sonsoles Hortelano, Miriam Zeini, Paqui G Trav\\xc3\\xa9s, Lisardo Bosc\\xc3\\xa. Nitric oxide and cell signaling: in vivo evaluation of NO-dependent apoptosis by MRI and not NMR techniques. Methods in enzymology. vol 396. 2006-01-24. PMID:16291264.' apoptosis plays a key role in many pathological circumstances, such as neurodegenerative diseases. 2006-01-24 2023-08-12 Not clear
Faris Q Alenz. Apoptosis and diseases: regulation and clinical relevance. Saudi medical journal. vol 26. issue 11. 2006-01-23. PMID:16311648. for instance, an increase in apoptosis leads to cell loss accompanied by neurodegenerative diseases, whereas we know that genetically determined defects of apoptosis result in deregulated cell proliferation, typical of cancer. 2006-01-23 2023-08-12 human
Hwa Sun Kim, Chan Kee Par. Retinal ganglion cell death is delayed by activation of retinal intrinsic cell survival program. Brain research. vol 1057. issue 1-2. 2006-01-04. PMID:16139821. neuronal cells undergo apoptosis when deprived of neurotrophic factors due to injury, trauma, or neurodegenerative disease. 2006-01-04 2023-08-12 human
Y Huang, N Erdmann, H Peng, Y Zhao, Jialin Zhen. The role of TNF related apoptosis-inducing ligand in neurodegenerative diseases. Cellular & molecular immunology. vol 2. issue 2. 2005-12-12. PMID:16191417. in this review, we summarize the possible common aspects that trail involved those neurodegenerative diseases, trail induced apoptosis signaling in the cns cells, and specific role of trail in individual diseases. 2005-12-12 2023-08-12 Not clear
Marc Adrian Williams, Jadwiga Turchan, Yang Lu, Avindra Nath, Daniel B Drachma. Protection of human cerebral neurons from neurodegenerative insults by gene delivery of soluble tumor necrosis factor p75 receptor. Experimental brain research. vol 165. issue 3. 2005-12-01. PMID:15827736. apoptosis plays an important role in neuronal cell death in both chronic and acute human neurodegenerative diseases, including amyotrophic lateral sclerosis, huntington's disease, cerebral ischemia, and human immunodeficiency virus (hiv) encephalopathy. 2005-12-01 2023-08-12 human
Stéphane Bach, Marie Knockaert, Jens Reinhardt, Olivier Lozach, Sophie Schmitt, Blandine Baratte, Marcel Koken, Stephen P Coburn, Lin Tang, Tao Jiang, Dong-Cai Liang, Hervé Galons, Jean-Francois Dierick, Lorenzo A Pinna, Flavio Meggio, Frank Totzke, Christoph Schächtele, Andrea S Lerman, Amancio Carnero, Yongqin Wan, Nathanael Gray, Laurent Meije. Roscovitine targets, protein kinases and pyridoxal kinase. The Journal of biological chemistry. vol 280. issue 35. 2005-10-25. PMID:15975926. besides its use as a biological tool in cell cycle, neuronal functions, and apoptosis studies, it is currently evaluated as a potential drug to treat cancers, neurodegenerative diseases, viral infections, and glomerulonephritis. 2005-10-25 2023-08-12 Not clear
Gonzalo Arboleda, Catherine Waters, Rosemary M Gibso. Metabolic activity: a novel indicator of neuronal survival in the murine dopaminergic cell line CAD. Journal of molecular neuroscience : MN. vol 27. issue 1. 2005-10-13. PMID:16055947. apoptosis is implicated in many neurodegenerative diseases, including parkinson's disease (pd). 2005-10-13 2023-08-12 Not clear
Ravi Shankar Akundi, Eduardo Candelario-Jalil, Sandra Hess, Michael Hüll, Klaus Lieb, Peter J Gebicke-Haerter, Bernd L Fiebic. Signal transduction pathways regulating cyclooxygenase-2 in lipopolysaccharide-activated primary rat microglia. Glia. vol 51. issue 3. 2005-09-08. PMID:15800925. this potential nature of ceramides in activating microglia suggests that endogenously produced ceramides during neuronal apoptosis in ischemia or neurodegenerative diseases could also contribute to the amplification of neuroinflammatory events. 2005-09-08 2023-08-12 rat
Pascale Gaillard, Isabelle Jeanclaude-Etter, Vittoria Ardissone, Steve Arkinstall, Yves Cambet, Montserrat Camps, Christian Chabert, Dennis Church, Rocco Cirillo, Denise Gretener, Serge Halazy, Anthony Nichols, Cedric Szyndralewiez, Pierre-Alain Vitte, Jean-Pierre Gottelan. Design and synthesis of the first generation of novel potent, selective, and in vivo active (benzothiazol-2-yl)acetonitrile inhibitors of the c-Jun N-terminal kinase. Journal of medicinal chemistry. vol 48. issue 14. 2005-08-16. PMID:15999997. several lines of evidence support the hypothesis that c-jun n-terminal kinase (jnks) plays a critical role in a wide range of diseases including cell death (apoptosis)-related disorders (neurodegenerative diseases, brain, heart, and renal ischemia, epilepsy) and inflammatory disorders (multiple sclerosis, rheumatoid arthritis, inflammatory bowel diseases). 2005-08-16 2023-08-12 rat
Jin Zhong, Jixian Deng, Jennifer Phan, Stephen Dlouhy, Huangbing Wu, Weiguo Yao, Ping Ye, A Joseph D'Ercole, Wei-Hua Le. Insulin-like growth factor-I protects granule neurons from apoptosis and improves ataxia in weaver mice. Journal of neuroscience research. vol 80. issue 4. 2005-07-25. PMID:15846777. these results confirm our previous suggestion that a lack of igf-i activity contributes to apoptosis of weaver granule neurons in vivo and supports igf-i's potential therapeutic use in neurodegenerative disease. 2005-07-25 2023-08-12 mouse
Min Deng, Jin Yuan Zhao, Peng Fei Tu, Yong Jiang, Zheng Bin Li, Yao Hong Wan. Echinacoside rescues the SHSY5Y neuronal cells from TNFalpha-induced apoptosis. European journal of pharmacology. vol 505. issue 1-3. 2005-05-16. PMID:15556132. thus, echinacoside has the neuroprotective capacity to antagonize tnfalpha-induced apoptosis in shsy5y cells and may be useful in treating some neurodegenerative diseases. 2005-05-16 2023-08-12 human
De-Maw Chuang, Christopher Hough, Vladimir V Senatoro. Glyceraldehyde-3-phosphate dehydrogenase, apoptosis, and neurodegenerative diseases. Annual review of pharmacology and toxicology. vol 45. 2005-05-12. PMID:15822178. glyceraldehyde-3-phosphate dehydrogenase, apoptosis, and neurodegenerative diseases. 2005-05-12 2023-08-12 Not clear
Manus W Ward, Donat Kögel, Jochen H M Preh. Neuronal apoptosis: BH3-only proteins the real killers? Journal of bioenergetics and biomembranes. vol 36. issue 4. 2005-04-20. PMID:15377860. at present there is a poor understanding of the events that lead up to neuronal apoptosis that occurs in neurodegenerative diseases and following acute ischemic episodes. 2005-04-20 2023-08-12 Not clear
Alfons Lawen, Jennifer D Ly, Darius J R Lane, Kristof Zarschler, Angela Messina, Vito De Pint. Voltage-dependent anion-selective channel 1 (VDAC1)--a mitochondrial protein, rediscovered as a novel enzyme in the plasma membrane. The international journal of biochemistry & cell biology. vol 37. issue 2. 2005-03-29. PMID:15474974. regulation of the enzyme will have impacts on cancer and autoimmune diseases (insufficient apoptosis) as well as neurodegenerative diseases (excessive apoptosis). 2005-03-29 2023-08-12 Not clear
Rebecca Clayton, John B Clark, Martyn Sharp. Cytochrome c release from rat brain mitochondria is proportional to the mitochondrial functional deficit: implications for apoptosis and neurodegenerative disease. Journal of neurochemistry. vol 92. issue 4. 2005-03-21. PMID:15686486. cytochrome c release from rat brain mitochondria is proportional to the mitochondrial functional deficit: implications for apoptosis and neurodegenerative disease. 2005-03-21 2023-08-12 rat
Anne Marcilha. [Intracellular signaling pathways, apoptosis and neurodegenerative diseases]. Psychologie & neuropsychiatrie du vieillissement. vol 2. issue 3. 2005-03-01. PMID:15689335. [intracellular signaling pathways, apoptosis and neurodegenerative diseases]. 2005-03-01 2023-08-12 Not clear
Thomas Rückle, Marco Biamonte, Tania Grippi-Vallotton, Steve Arkinstall, Yves Cambet, Montserrat Camps, Christian Chabert, Dennis J Church, Serge Halazy, Xuliang Jiang, Isabelle Martinou, Anthony Nichols, Wolfgang Sauer, Jean-Pierre Gottelan. Design, synthesis, and biological activity of novel, potent, and selective (benzoylaminomethyl)thiophene sulfonamide inhibitors of c-Jun-N-terminal kinase. Journal of medicinal chemistry. vol 47. issue 27. 2005-02-14. PMID:15615541. several lines of evidence support the hypothesis that c-jun n-terminal kinases (jnks) play a critical role in a wide range of disease states including cell death (apoptosis)-related and inflammatory disorders (epilepsy, brain, heart and renal ischemia, neurodegenerative diseases, multiple sclerosis, rheumatoid arthritis, and inflammatory bowel syndrome). 2005-02-14 2023-08-12 Not clear
Tetsumori Yamashim. Ca2+-dependent proteases in ischemic neuronal death: a conserved 'calpain-cathepsin cascade' from nematodes to primates. Cell calcium. vol 36. issue 3-4. 2005-01-27. PMID:15261484. recent data suggest that necrosis rather than apoptosis appear to be the crucial component of the damage to the nervous system during human ischemic injuries and neurodegenerative diseases. 2005-01-27 2023-08-12 human
Fumitaka Osakada, Asami Hashino, Toshiaki Kume, Hiroshi Katsuki, Shuji Kaneko, Akinori Akaik. Alpha-tocotrienol provides the most potent neuroprotection among vitamin E analogs on cultured striatal neurons. Neuropharmacology. vol 47. issue 6. 2005-01-13. PMID:15527824. oxidative stress and apoptosis play pivotal roles in the pathogenesis of neurodegenerative diseases. 2005-01-13 2023-08-12 rat