| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cristina Barca, Amanda J Kiliaan, Lydia Wachsmuth, Claudia Foray, Sven Hermann, Cornelius Faber, Michael Schaefers, Maximilian Wiesmann, Bastian Zinnhardt, Andreas H Jacob. Short-term colony stimulating factor-1 receptor inhibition-induced repopulation after stroke assessed by longitudinal Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2022-02-04. PMID:35115368. |
short-term colony stimulating factor-1 receptor inhibition-induced repopulation after stroke assessed by longitudinal studies on colony stimulating factor-1 receptor (csf-1r) inhibition-induced microglia depletion indicated that inhibitor withdrawal allowed the renewal of the microglial compartment via repopulation and resolved the inflammatory imbalance. |
2022-02-04 |
2023-08-13 |
mouse |
| Junqiu Jia, Lixuan Yang, Yan Chen, Lili Zheng, Yanting Chen, Yun Xu, Meijuan Zhan. The Role of Microglial Phagocytosis in Ischemic Stroke. Frontiers in immunology. vol 12. 2022-01-27. PMID:35082781. |
during the past decades, microglial polarization and chemotactic properties have been well-studied, whereas less attention has been paid to phagocytic phenotypes of microglia in stroke. |
2022-01-27 |
2023-08-13 |
Not clear |
| Junqiu Jia, Lixuan Yang, Yan Chen, Lili Zheng, Yanting Chen, Yun Xu, Meijuan Zhan. The Role of Microglial Phagocytosis in Ischemic Stroke. Frontiers in immunology. vol 12. 2022-01-27. PMID:35082781. |
generally, whether phagocytosis mediated by microglia plays a beneficial or detrimental role in stroke remains controversial, which calls for further investigations. |
2022-01-27 |
2023-08-13 |
Not clear |
| Yao Lin, Tingting Huang, Weimin Shen, Qiongyi Pang, Qingfeng Xie, Xiang Chen, Fengxia T. TRPV1 Suppressed NLRP3 Through Regulating Autophagy in Microglia After Ischemia-Reperfusion Injury. Journal of molecular neuroscience : MN. 2022-01-18. PMID:35041191. |
in recent years, it has been reported that autophagy in microglia played an important role in inflammatory response after stroke. |
2022-01-18 |
2023-08-13 |
Not clear |
| Mandeep Kaur, Saurabh Sharm. Molecular mechanisms of cognitive impairment associated with stroke. Metabolic brain disease. 2022-01-14. PMID:35029798. |
the pathophysiology of stroke associated cognitive impairment is complex and recent molecular, cellular, and animal models studies have revealed that multiple cellular changes have been implicated, including altered redox state, mitochondrial dysfunction, disruption of the blood-brain barrier, perivascular spacing, glymphatic system impairment, microglia activation and amyloid-β deposition in the parenchyma of the brain. |
2022-01-14 |
2023-08-13 |
Not clear |
| Xiao-Wen Lian, Bin Lu. Knockdown of NEAT1 induced microglial M2 polarization via miR‑374a‑5p/NFAT5 axis to inhibit inflammatory response caused by OGD/R. Acta neurobiologiae experimentalis. vol 81. issue 4. 2022-01-11. PMID:35014985. |
knockdown of neat1 regulated ogd/r injury of chme5 cells via mir‑374a‑5p/nfat5 axis to induce the shifting of microglia from m1 to m2 and inhibit inflammatory response, making it a potential target for stroke treatment. |
2022-01-11 |
2023-08-13 |
Not clear |
| Ming-Xing Cheng, Chen-Hui Li, Wei Meng, Chen Wan. [Dual roles and mechanism of microglia in ischemic stroke]. Sheng li xue bao : [Acta physiologica Sinica]. vol 73. issue 6. 2021-12-28. PMID:34961871. |
here, we briefly describe the mechanism of microglia activation after stroke, and comprehensively review the dual role of microglia in neurodegeneration and regeneration after stroke. |
2021-12-28 |
2023-08-13 |
Not clear |
| Ming-Xing Cheng, Chen-Hui Li, Wei Meng, Chen Wan. [Dual roles and mechanism of microglia in ischemic stroke]. Sheng li xue bao : [Acta physiologica Sinica]. vol 73. issue 6. 2021-12-28. PMID:34961871. |
in-depth exploration of the cytotoxic and protective mechanisms of microglia will provide new targets and new strategies for stroke treatment. |
2021-12-28 |
2023-08-13 |
Not clear |
| Susanna R Var, Anala V Shetty, Andrew W Grande, Walter C Low, Maxim C Cheera. Microglia and Macrophages in Neuroprotection, Neurogenesis, and Emerging Therapies for Stroke. Cells. vol 10. issue 12. 2021-12-24. PMID:34944064. |
microglia and macrophages in neuroprotection, neurogenesis, and emerging therapies for stroke. |
2021-12-24 |
2023-08-13 |
Not clear |
| Guy C Brow. Neuronal Loss after Stroke Due to Microglial Phagocytosis of Stressed Neurons. International journal of molecular sciences. vol 22. issue 24. 2021-12-24. PMID:34948237. |
phagocytic receptors on microglia may be attractive treatment targets to prevent delayed neuronal loss after stroke due to the microglial phagocytosis of stressed neurons. |
2021-12-24 |
2023-08-13 |
Not clear |
| Fangfang Zhao, Haiping Zhao, Junfen Fan, Rongliang Wang, Ziping Han, Zhen Tao, Yangmin Zheng, Feng Yan, Yuyou Huang, Lei Yu, Xu Zhang, Xiaolong Qi, Lianfeng Zhang, Yumin Luo, Yuanwu M. MiR-29a Knockout Aggravates Neurological Damage by Pre-polarizing M1 Microglia in Experimental Rat Models of Acute Stroke. Frontiers in genetics. vol 12. 2021-12-10. PMID:33790947. |
mir-29a knockout aggravates neurological damage by pre-polarizing m1 microglia in experimental rat models of acute stroke. |
2021-12-10 |
2023-08-13 |
rat |
| Fangfang Zhao, Haiping Zhao, Junfen Fan, Rongliang Wang, Ziping Han, Zhen Tao, Yangmin Zheng, Feng Yan, Yuyou Huang, Lei Yu, Xu Zhang, Xiaolong Qi, Lianfeng Zhang, Yumin Luo, Yuanwu M. Corrigendum: MiR-29a Knockout Aggravates Neurological Damage by Pre-polarizing M1 Microglia in Experimental Rat Models of Acute Stroke. Frontiers in genetics. vol 12. 2021-12-10. PMID:34764981. |
corrigendum: mir-29a knockout aggravates neurological damage by pre-polarizing m1 microglia in experimental rat models of acute stroke. |
2021-12-10 |
2023-08-13 |
rat |
| Yuanyuan Ran, Shuyan Qie, Fuhai Gao, Zitong Ding, Shuiqing Yang, Guiqin Tian, Zongjian Liu, Jianing X. Baicalein ameliorates ischemic brain damage through suppressing proinflammatory microglia polarization via inhibiting the TLR4/NF-κB and STAT1 pathway. Brain research. vol 1770. 2021-12-09. PMID:34418356. |
baicalein indirectly ameliorates neuronal injury after stroke by polarizing microglia toward the anti-inflammatory phenotype via inhibition of the tlr4/nf-κb pathway and down-regulation of phosphorylated stat1, suggesting that baicalein might serve a potential therapy for stroke. |
2021-12-09 |
2023-08-13 |
mouse |
| Lu Wang, Zihui Deng, Yan Zhao, Rui Yuan, Mengmeng Yang, Yu Zhang, Yun Li, Yuyan Liu, Feihu Zhou, Hongjun Kan. Mesenchymal stem cells regulate activation of microglia cells to improve hippocampal injury of heat stroke rats. Journal of thermal biology. vol 101. 2021-12-09. PMID:34879909. |
mesenchymal stem cells regulate activation of microglia cells to improve hippocampal injury of heat stroke rats. |
2021-12-09 |
2023-08-13 |
rat |
| Lu Wang, Zihui Deng, Yan Zhao, Rui Yuan, Mengmeng Yang, Yu Zhang, Yun Li, Yuyan Liu, Feihu Zhou, Hongjun Kan. Mesenchymal stem cells regulate activation of microglia cells to improve hippocampal injury of heat stroke rats. Journal of thermal biology. vol 101. 2021-12-09. PMID:34879909. |
in addition, mscs treatment can significantly inhibit the over-activation of hippocampal microglia in heat stroke rats and the levels of pro-inflammatory factors and chemokines in the hippocampus. |
2021-12-09 |
2023-08-13 |
rat |
| Lu Wang, Zihui Deng, Yan Zhao, Rui Yuan, Mengmeng Yang, Yu Zhang, Yun Li, Yuyan Liu, Feihu Zhou, Hongjun Kan. Mesenchymal stem cells regulate activation of microglia cells to improve hippocampal injury of heat stroke rats. Journal of thermal biology. vol 101. 2021-12-09. PMID:34879909. |
early treatment of mscs can greatly promote the activation of cerebellar microglia in heat stroke rats. |
2021-12-09 |
2023-08-13 |
rat |
| Lu Wang, Zihui Deng, Yan Zhao, Rui Yuan, Mengmeng Yang, Yu Zhang, Yun Li, Yuyan Liu, Feihu Zhou, Hongjun Kan. Mesenchymal stem cells regulate activation of microglia cells to improve hippocampal injury of heat stroke rats. Journal of thermal biology. vol 101. 2021-12-09. PMID:34879909. |
in conclusion, the application of mscs in the treatment of heat stroke in rats can significantly reduce mortality and neurological deficits and improve hippocampal damage, possibly by inhibiting the excessive activation of hippocampal microglia in heat stroke rats. |
2021-12-09 |
2023-08-13 |
rat |
| Zhijuan Cao, Sean S Harvey, Terrance Chiang, Aulden G Foltz, Alex G Lee, Michelle Y Cheng, Gary K Steinber. Unique Subtype of Microglia in Degenerative Thalamus After Cortical Stroke. Stroke. vol 52. issue 2. 2021-12-07. PMID:33412903. |
unique subtype of microglia in degenerative thalamus after cortical stroke. |
2021-12-07 |
2023-08-13 |
Not clear |
| Matthieu Lecuyer, Praneeti Pathipati, Joel Faustino, Zinaida S Vexle. Neonatal stroke enhances interaction of microglia-derived extracellular vesicles with microglial cells. Neurobiology of disease. vol 157. 2021-12-06. PMID:34153465. |
we asked whether neonatal stroke alters release of microglial evs (mev) and mev communication with activated microglia. |
2021-12-06 |
2023-08-13 |
mouse |
| Matthieu Lecuyer, Praneeti Pathipati, Joel Faustino, Zinaida S Vexle. Neonatal stroke enhances interaction of microglia-derived extracellular vesicles with microglial cells. Neurobiology of disease. vol 157. 2021-12-06. PMID:34153465. |
cumulatively, these data demonstrate that microglial cells release both microvesicles and exosomes in naïve neonatal brain, that the state of microglial activation determines both properties of released evs and their recognition/uptake by microglia in ischemic-reperfused and control regions, suggesting a modulatory role of mev in neonatal stroke, and that sphingosine/n-smase-2 signaling contributes both to evs release and uptake (predominantly p4-mev) after neonatal stroke. |
2021-12-06 |
2023-08-13 |
mouse |