Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
A Inanobe, Y Yoshimoto, Y Horio, K I Morishige, H Hibino, S Matsumoto, Y Tokunaga, T Maeda, Y Hata, Y Takai, Y Kurach. Characterization of G-protein-gated K+ channels composed of Kir3.2 subunits in dopaminergic neurons of the substantia nigra. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 3. 1999-02-25. PMID:9920664. |
in substantia nigra (sn), however, mrna of kir3.1 does not express, whereas that of kir3.2 clearly does. |
1999-02-25 |
2023-08-12 |
Not clear |
T F Oo, C Henchcliffe, D James, R E Burk. Expression of c-fos, c-jun, and c-jun N-terminal kinase (JNK) in a developmental model of induced apoptotic death in neurons of the substantia nigra. Journal of neurochemistry. vol 72. issue 2. 1999-02-11. PMID:9930727. |
we have shown that programmed cell death, with the morphology of apoptosis, occurs in dopamine neurons of the substantia nigra (sn) during normal postnatal development and that this death event can be induced by early striatal target injury. |
1999-02-11 |
2023-08-12 |
Not clear |
M E Olds, D B Jacques, O Kopyo. Globus pallidus lesions depress the excitatory responses to apomorphine but not amphetamine in the subthalamic nucleus of the behaving rat with a 6-OHDA nigra lesion. Brain research. vol 812. issue 1-2. 1999-02-10. PMID:9813239. |
bilateral electrolytic lesions of the globus pallidus (gp), superimposed on the earlier unilateral lesion in substantia nigra (sn) with 6-hydroxydopamine (6-ohda) affected differently the excitatory responses in the stn evoked by amphetamine and apomorphine and the motor responses to the drugs recorded concurrently. |
1999-02-10 |
2023-08-12 |
rat |
S H Tseng, S M Li. Substantia nigra lesion suppresses the antagonistic effects of N-methyl-D-aspartate receptor antagonist (MK-801) on the autotomy in the rat. Neuroscience letters. vol 255. issue 3. 1999-02-10. PMID:9832199. |
rats received right dorsal root ganglionectomy (drgn) to induce autotomy, and were treated with mk-801 and/or left substantia nigra (sn) lesion after drgn. |
1999-02-10 |
2023-08-12 |
rat |
J H Son, H S Chun, T H Joh, S Cho, B Conti, J W Le. Neuroprotection and neuronal differentiation studies using substantia nigra dopaminergic cells derived from transgenic mouse embryos. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 1. 1999-02-05. PMID:9870933. |
the major pathological lesion of parkinson's disease (pd) is the selective cell death of dopaminergic (da) neurons in substantia nigra (sn). |
1999-02-05 |
2023-08-12 |
mouse |
D L Choi-Lundberg, Q Lin, T Schallert, D Crippens, B L Davidson, Y N Chang, Y L Chiang, J Qian, L Bardwaj, M C Boh. Behavioral and cellular protection of rat dopaminergic neurons by an adenoviral vector encoding glial cell line-derived neurotrophic factor. Experimental neurology. vol 154. issue 2. 1999-02-04. PMID:9878166. |
previously, we observed that an adenoviral (ad) vector encoding human glial cell line-derived neurotrophic factor (gdnf), injected near the rat substantia nigra (sn), protects sn dopaminergic (da) neuronal soma from 6-hydroxydopamine (6-ohda)-induced degeneration. |
1999-02-04 |
2023-08-12 |
human |
B Hontanilla, A Parent, S de las Heras, J M Giménez-Amay. Distribution of calbindin D-28k and parvalbumin neurons and fibers in the rat basal ganglia. Brain research bulletin. vol 47. issue 2. 1999-01-22. PMID:9820727. |
these findings reveal that cb and pv are distributed according to a highly heterogeneous pattern in the caudate putamen complex (cpu), globus pallidus (gp), entopeduncular nucleus (ep), subthalamic nucleus (sth) and substantia nigra (sn) of the rat. |
1999-01-22 |
2023-08-12 |
rat |
F A Dajas-Bailador, A Martinez-Borges, G Costa, J A Abin, E Martignoni, G Nappi, F Daja. Hydroxyl radical production in the substantia nigra after 6-hydroxydopamine and hypoxia-reoxygenation. Brain research. vol 813. issue 1. 1999-01-20. PMID:9824659. |
in the substantia nigra (sn) and the striatum (cs) several moments after intranigral injection of the neurotoxin, with or without an added episode of hypoxia (30 min, 95% n2, 5% o2). |
1999-01-20 |
2023-08-12 |
Not clear |
B K Jin, D Y Shin, M Y Jeong, M R Gwag, H W Baik, K S Yoon, Y H Cho, W S Joo, Y S Kim, H H Bai. Melatonin protects nigral dopaminergic neurons from 1-methyl-4-phenylpyridinium (MPP+) neurotoxicity in rats. Neuroscience letters. vol 245. issue 2. 1999-01-07. PMID:9605485. |
in the present study, the in vivo neuroprotective effects of melatonin, as an antioxidant, were assessed in sprague-dawley rats with a unilateral lesion of substantia nigra (sn) caused by a stereotaxic injection of neurotoxin, 1-methyl-4-phenylpyridinium (mpp+). |
1999-01-07 |
2023-08-12 |
rat |
D C Silveira, Z Liu, S de LaCalle, J Lu, P Klein, G L Holmes, A G Herzo. Activation of the locus coeruleus after amygdaloid kindling. Epilepsia. vol 39. issue 12. 1998-12-30. PMID:9860060. |
substantia nigra (sn) and locus coeruleus (lc) neurons are implicated in the propagation and suppression of amygdaloid seizures. |
1998-12-30 |
2023-08-12 |
Not clear |
K J Elliott, J M Jones, A I Sacaan, G K Lloyd, J Corey-Naev. 6-hydroxydopamine lesion of rat nigrostriatal dopaminergic neurons differentially affects nicotinic acetylcholine receptor subunit mRNA expression. Journal of molecular neuroscience : MN. vol 10. issue 3. 1998-12-08. PMID:9770646. |
nicotinic acetylcholine receptor (nachr) subunit mrna expression in the rat substantia nigra (sn) was assayed by semiquantitative rt-pcr following 6-hydroxydopamine (6-ohda) lesion of nigrostriatal dopaminergic neurons. |
1998-12-08 |
2023-08-12 |
rat |
A F Hoffman, C R Lupica, G A Gerhard. Dopamine transporter activity in the substantia nigra and striatum assessed by high-speed chronoamperometric recordings in brain slices. The Journal of pharmacology and experimental therapeutics. vol 287. issue 2. 1998-12-07. PMID:9808671. |
high-speed chronoamperometric measurements were used to measure clearance of locally applied dopamine (da) in rat brain slices containing the substantia nigra (sn) or striatum. |
1998-12-07 |
2023-08-12 |
rat |
K K Yung, Y C Tse, Z G Gao, S Y Choi, F S Kwo. Localization of GABA transaminase immunoreactivity in the rat substantia nigra pars reticulata. Neuroscience letters. vol 253. issue 1. 1998-12-02. PMID:9754804. |
precise cellular localization of gamma-aminobutyric acid transaminase (gaba(t)), a degrading enzyme for the neurotransmitter gaba, was determined in the rat substantia nigra (sn) by immunocytochemical experiments using a recently developed monoclonal antibody. |
1998-12-02 |
2023-08-12 |
rat |
M Kohutnicka, E Lewandowska, I Kurkowska-Jastrzebska, A Członkowski, A Członkowsk. Microglial and astrocytic involvement in a murine model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Immunopharmacology. vol 39. issue 3. 1998-12-01. PMID:9754903. |
a transient microglial reaction was demonstrated from the 1st until the 14th day in the substantia nigra (sn) and striatum. |
1998-12-01 |
2023-08-12 |
mouse |
I T Demchenko, A E Boso, M J Natoli, P O Doar, T J O'Neill, P B Bennett, C A Piantados. Measurement of cerebral blood flow in rats and mice by hydrogen clearance during hyperbaric oxygen exposure. Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc. vol 25. issue 3. 1998-11-02. PMID:9789333. |
polarographic platinum electrodes 0.1 mm in diameter were used to record h2 clearance curves from the parietal cortex (pc), substantia nigra (sn), and caudate putamen nucleus (cpn) after inhalation of 2.5% h2 in air. |
1998-11-02 |
2023-08-12 |
mouse |
A M Lin, C H Yang, C Y Cha. Striatal dopamine dynamics are altered following an intranigral infusion of iron in adult rats. Free radical biology & medicine. vol 24. issue 6. 1998-10-30. PMID:9607609. |
seven days after an intranigral infusion of iron, oxidative stress was confirmed by an elevated lipid peroxidation in lesioned substantia nigra (sn). |
1998-10-30 |
2023-08-12 |
rat |
K Thorré, S Sarre, I Smolders, G Ebinger, Y Michott. Dopaminergic regulation of serotonin release in the substantia nigra of the freely moving rat using microdialysis. Brain research. vol 796. issue 1-2. 1998-10-29. PMID:9689460. |
the functional regulation by dopamine (da) receptors of serotonin (5-ht) release from the rat substantia nigra (sn) was investigated using in vivo microdialysis. |
1998-10-29 |
2023-08-12 |
rat |
K Thorré, G Ebinger, Y Michott. 5-HT4 receptor involvement in the serotonin-enhanced dopamine efflux from the substantia nigra of the freely moving rat: a microdialysis study. Brain research. vol 796. issue 1-2. 1998-10-29. PMID:9689461. |
the functional regulation by serotonin (5-ht) receptors of the 5-ht-enhanced dopamine (da) release from the rat substantia nigra (sn) was investigated using in vivo microdialysis. |
1998-10-29 |
2023-08-12 |
rat |
G L Willis, S M Armstron. Orphan neurones and amine excess: the functional neuropathology of Parkinsonism and neuropsychiatric disease. Brain research. Brain research reviews. vol 27. issue 3. 1998-10-22. PMID:9729369. |
in section 3 it is suggested that parkinsonism is due to a da excess far from the striatum in the area of the posterior lateral hypothalamus (plh) and the substantia nigra (sn). |
1998-10-22 |
2023-08-12 |
human |
S Mohanty, H W Steinbusch, D K Ganguly, K P Mohanakuma. Behavioral and neurochemical alterations following intracerebroventricular administration of anti-serotonin antibodies in adult Balb/c mice. Journal of chemical neuroanatomy. vol 14. issue 3-4. 1998-10-20. PMID:9704892. |
5-ht and da in the nucleus raphe dorsalis (nrd), substantia nigra (sn), nucleus caudatus putamen (ncp) and in the substantia grisea centralis, and ne in the former two nuclei were significantly decreased in these animals. |
1998-10-20 |
2023-08-12 |
mouse |