| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S M Johnson, P T Bywoo. Excitatory amino acid-induced degeneration of dendrites of catecholamine neurons in rat substantia nigra. Experimental neurology. vol 151. issue 2. 1998-07-09. PMID:9628758. |
we have recently established a rat substantia nigra (sn) slice preparation in which a sensitive index of excitatory amino acid (eaa) toxicity was degeneration of the dendritic arbor of catecholamine neurons labelled by immunostaining for tyrosine hydroxylase (th). |
1998-07-09 |
2023-08-12 |
rat |
| I Grofova, M Zho. Nigral innervation of cholinergic and glutamatergic cells in the rat mesopontine tegmentum: light and electron microscopic anterograde tracing and immunohistochemical studies. The Journal of comparative neurology. vol 395. issue 3. 1998-07-08. PMID:9596529. |
the substantia nigra (sn) has long been known as an important source of afferents to the pedunculopontine tegmental nucleus (ppn). |
1998-07-08 |
2023-08-12 |
rat |
| H Moore, C L Todd, A A Grac. Striatal extracellular dopamine levels in rats with haloperidol-induced depolarization block of substantia nigra dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 13. 1998-07-02. PMID:9634572. |
correlations between substantia nigra (sn) dopamine (da) cell activity and striatal extracellular da were examined using simultaneous extracellular single-unit recordings and in vivo microdialysis performed in drug-naive rats and in rats treated repeatedly with haloperidol (hal). |
1998-07-02 |
2023-08-12 |
rat |
| R F Seegal, B A Pappas, G A Par. Neurochemical effects of consumption of Great Lakes salmon by rats. Regulatory toxicology and pharmacology : RTP. vol 27. issue 1 Pt 2. 1998-06-23. PMID:9618335. |
concentrations of biogenic amines, their metabolites, and choline acetyltransferase (chat) were determined in the frontal cortex (fc), nucleus accumbens, caudate nucleus (cn), hippocampus (hc), and substantia nigra (sn) of adult rats who had been exposed, both perinatally and as adults, to standard rat chow adulterated with either 5 or 20% (w/w) lyophilized fillets from either lake huron (lh) or lake ontario (lo) salmon. |
1998-06-23 |
2023-08-12 |
human |
| N S Kolomeets, N A Uranov. [Synaptic contacts in schizophrenia: study with immunocytochemical identification of dopaminergic neurons]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 97. issue 12. 1998-06-09. PMID:9591064. |
the ultrastructure of synaptic contacts located on dopaminergic (tyrosine hydroxylase immunopositive--tp) neurons was investigated in substantia nigra (sn) of postmortem brains in 4 schizophrenic patients compared to 3 mentally healthy control cases. |
1998-06-09 |
2023-08-12 |
Not clear |
| D F Brown, M A Dababo, E H Bigio, R C Risser, K P Eagan, C L Hladik, C L Whit. Neuropathologic evidence that the Lewy body variant of Alzheimer disease represents coexistence of Alzheimer disease and idiopathic Parkinson disease. Journal of neuropathology and experimental neurology. vol 57. issue 1. 1998-06-08. PMID:9600196. |
we retrieved 30 autopsy cases in which lewy bodies (lb) had been identified in the substantia nigra (sn) in routine hematoxylin-eosin-stained sections. |
1998-06-08 |
2023-08-12 |
rabbit |
| M Turgu. Asymmetry of sympathetic activity in a rat model of Parkinson's disease induced by 6-hydroxydopamine: haemodynamic, electrocardiographic and biochemical changes. Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie. vol 197. issue 5. 1998-05-27. PMID:9561558. |
one day after apomorphine testing following lesioning of the substantia nigra (sn) with 6-ohda, heart rate (hr), mean arterial blood pressure (map), and electrocardiogram (ecg) were monitored. |
1998-05-27 |
2023-08-12 |
rat |
| Y He, T Lee, S K Leon. Effect of 6-OHDA injection on the AMPA glutamate receptor subunits in the substantia nigra of Sprague-Dawley rats. Neuroscience letters. vol 241. issue 1. 1998-04-28. PMID:9502201. |
parkinson's disease (pd) is characterized by the destruction of dopaminergic cells in the substantia nigra (sn). |
1998-04-28 |
2023-08-12 |
rat |
| T González-Hernández, P Abdala, M Rodrígue. NOS expression in nigral cells after excitotoxic and non-excitotoxic lesion of the pedunculopontine tegmental nucleus. The European journal of neuroscience. vol 9. issue 12. 1998-04-24. PMID:9517471. |
the substantia nigra (sn) receives afferents from cholinergic neurons of the pedunculopontine tegmental nucleus (pptg), a neuronal population that shows high levels of nitric oxide synthase (nos), the enzyme responsible for the synthesis of nitric oxide. |
1998-04-24 |
2023-08-12 |
rat |
| W Löscher, U Ebert, H Lehmann, C Rosenthal, G Nikkha. Seizure suppression in kindling epilepsy by grafts of fetal GABAergic neurons in rat substantia nigra. Journal of neuroscience research. vol 51. issue 2. 1998-03-30. PMID:9469573. |
we previously showed that amygdala kindling results in a significant decrease of gaba and its synthesizing enzyme glutamate decarboxylase in substantia nigra (sn), i.e., a region thought to be critically involved in seizure propagation in various models of epilepsy. |
1998-03-30 |
2023-08-12 |
rat |
| Y Chen, E Engidawork, F Loidl, E Dell'Anna, M Goiny, G Lubec, K Andersson, M Herrera-Marschit. Short- and long-term effects of perinatal asphyxia on monoamine, amino acid and glycolysis product levels measured in the basal ganglia of the rat. Brain research. Developmental brain research. vol 104. issue 1-2. 1998-03-20. PMID:9466704. |
the effects of perinatal asphyxia on levels of dopamine (da) and its metabolites, amino acids and glycolysis products, measured in tissue samples from substantia nigra (sn), striatum, ventral tegmental area (vta), and nucleus accumbens (acb), were studied 80 min to 8 days after birth with high performance liquid chromatography (hplc). |
1998-03-20 |
2023-08-12 |
rat |
| Y Fang, A Janowsky, O K Rønneklei. Cocaine exposure in fetal rhesus monkey: consequences for dopamine D1- and D2-like receptor binding densities. Brain research. Developmental brain research. vol 104. issue 1-2. 1998-03-20. PMID:9466719. |
image analysis of receptor autoradiograms revealed a high-density dopamine d1-like receptor binding in the striatum, nucleus accumbens (acb) and the substantia nigra (sn), whereas lower binding densities were observed in the frontal cortex and the habenula (hb). |
1998-03-20 |
2023-08-12 |
monkey |
| T Shishido, Y Watanabe, I Matsuoka, H Nakanishi, S Niw. Acute methamphetamine administration increases tyrosine hydroxylase mRNA levels in the rat locus coeruleus. Brain research. Molecular brain research. vol 52. issue 1. 1998-03-10. PMID:9450687. |
tyrosine hydroxylase (th) mrna levels in the rat substantia nigra (sn), ventral tegmental area (vta) and locus coeruleus (lc) were measured by in situ hybridization histochemistry 1, 4, 6 and 24 h after a single injection of methamphetamine (map, 4 mg/kg, i.p.) |
1998-03-10 |
2023-08-12 |
rat |
| P E Schauwecker, J P Cogen, T Jiang, H W Cheng, T J Collier, T H McNeil. Differential regulation of astrocytic mRNAs in the rat striatum after lesions of the cortex or substantia nigra. Experimental neurology. vol 149. issue 1. 1998-03-06. PMID:9454618. |
this study evaluates the time course of expression of three astrocytic mrnas, glial fibrillary acidic protein (gfap), apolipoprotein e (apoe), and clusterin, in the rat striatum (st) following a unilateral lesion of either the cortex (cx) or the substantia nigra (sn), using northern blot and in situ hybridization analyses. |
1998-03-06 |
2023-08-12 |
rat |
| T J Counihan, G B Landwehrmeyer, D G Standaert, C M Kosinski, C R Scherzer, L P Daggett, G Veliçelebi, A B Young, J B Penne. Expression of N-methyl-D-aspartate receptor subunit mRNA in the human brain: mesencephalic dopaminergic neurons. The Journal of comparative neurology. vol 390. issue 1. 1998-03-03. PMID:9456178. |
however, detailed knowledge of the anatomical distribution and subtype specificity of glutamate receptors in the dopamine neurons of human substantia nigra (sn) has been lacking. |
1998-03-03 |
2023-08-12 |
human |
| H C Hung, E H Le. MPTP produces differential oxidative stress and antioxidative responses in the nigrostriatal and mesolimbic dopaminergic pathways. Free radical biology & medicine. vol 24. issue 1. 1998-03-02. PMID:9436616. |
results revealed that mptp increased lipid peroxidation in the striatum (st) and decreased glutathione concentration in the substantia nigra (sn) without markedly affecting these measures in the nucleus accumbens (nac) and ventral tegmental area (vta). |
1998-03-02 |
2023-08-12 |
mouse |
| P A Lapchak, D M Araujo, D C Hilt, J Sheng, S Jia. Adenoviral vector-mediated GDNF gene therapy in a rodent lesion model of late stage Parkinson's disease. Brain research. vol 777. issue 1-2. 1998-02-24. PMID:9449424. |
a recombinant adenoviral vector encoding the human glial cell line-derived neurotrophic factor (gdnf) gene (ad-gdnf) was used to express the neurotrophic factor gdnf in the unilaterally 6-hydroxydopamine (6-ohda) denervated substantia nigra (sn) of adult rats ten weeks following the 6-ohda injection. |
1998-02-24 |
2023-08-12 |
human |
| K Thorré, S Sarre, G Ebinger, Y Michott. Characterization of the extracellular serotonin release in the substantia nigra of the freely moving rat using microdialysis. Brain research. vol 772. issue 1-2. 1998-02-19. PMID:9406952. |
the characteristics of the serotonin release were investigated in the substantia nigra (sn) of the freely moving rat using microdialysis. |
1998-02-19 |
2023-08-12 |
rat |
| W Lu, M E Wol. Expression of dopamine transporter and vesicular monoamine transporter 2 mRNAs in rat midbrain after repeated amphetamine administration. Brain research. Molecular brain research. vol 49. issue 1-2. 1998-02-11. PMID:9387873. |
we examined ventral tegmental area (vta), substantia nigra (sn) and the transitional zone between vta and sn. |
1998-02-11 |
2023-08-12 |
rat |
| G J Kirouac, J Ciriell. Cardiovascular depressor responses to stimulation of substantia nigra and ventral tegmental area. The American journal of physiology. vol 273. issue 6. 1998-02-09. PMID:9435586. |
experiments were done in alpha-chloralose-anesthetized, paralyzed, and artificially ventilated rats to investigate the effect of l-glutamate (glu) stimulation of the substantia nigra (sn) and ventral tegmental area (vta) on arterial pressure (ap) and heart rate (hr). |
1998-02-09 |
2023-08-12 |
rat |