| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Hontanilla, A Parent, S de las Heras, J M Giménez-Amay. Distribution of calbindin D-28k and parvalbumin neurons and fibers in the rat basal ganglia. Brain research bulletin. vol 47. issue 2. 1999-01-22. PMID:9820727. |
these findings reveal that cb and pv are distributed according to a highly heterogeneous pattern in the caudate putamen complex (cpu), globus pallidus (gp), entopeduncular nucleus (ep), subthalamic nucleus (sth) and substantia nigra (sn) of the rat. |
1999-01-22 |
2023-08-12 |
rat |
| F A Dajas-Bailador, A Martinez-Borges, G Costa, J A Abin, E Martignoni, G Nappi, F Daja. Hydroxyl radical production in the substantia nigra after 6-hydroxydopamine and hypoxia-reoxygenation. Brain research. vol 813. issue 1. 1999-01-20. PMID:9824659. |
in the substantia nigra (sn) and the striatum (cs) several moments after intranigral injection of the neurotoxin, with or without an added episode of hypoxia (30 min, 95% n2, 5% o2). |
1999-01-20 |
2023-08-12 |
Not clear |
| B K Jin, D Y Shin, M Y Jeong, M R Gwag, H W Baik, K S Yoon, Y H Cho, W S Joo, Y S Kim, H H Bai. Melatonin protects nigral dopaminergic neurons from 1-methyl-4-phenylpyridinium (MPP+) neurotoxicity in rats. Neuroscience letters. vol 245. issue 2. 1999-01-07. PMID:9605485. |
in the present study, the in vivo neuroprotective effects of melatonin, as an antioxidant, were assessed in sprague-dawley rats with a unilateral lesion of substantia nigra (sn) caused by a stereotaxic injection of neurotoxin, 1-methyl-4-phenylpyridinium (mpp+). |
1999-01-07 |
2023-08-12 |
rat |
| D C Silveira, Z Liu, S de LaCalle, J Lu, P Klein, G L Holmes, A G Herzo. Activation of the locus coeruleus after amygdaloid kindling. Epilepsia. vol 39. issue 12. 1998-12-30. PMID:9860060. |
substantia nigra (sn) and locus coeruleus (lc) neurons are implicated in the propagation and suppression of amygdaloid seizures. |
1998-12-30 |
2023-08-12 |
Not clear |
| K J Elliott, J M Jones, A I Sacaan, G K Lloyd, J Corey-Naev. 6-hydroxydopamine lesion of rat nigrostriatal dopaminergic neurons differentially affects nicotinic acetylcholine receptor subunit mRNA expression. Journal of molecular neuroscience : MN. vol 10. issue 3. 1998-12-08. PMID:9770646. |
nicotinic acetylcholine receptor (nachr) subunit mrna expression in the rat substantia nigra (sn) was assayed by semiquantitative rt-pcr following 6-hydroxydopamine (6-ohda) lesion of nigrostriatal dopaminergic neurons. |
1998-12-08 |
2023-08-12 |
rat |
| A F Hoffman, C R Lupica, G A Gerhard. Dopamine transporter activity in the substantia nigra and striatum assessed by high-speed chronoamperometric recordings in brain slices. The Journal of pharmacology and experimental therapeutics. vol 287. issue 2. 1998-12-07. PMID:9808671. |
high-speed chronoamperometric measurements were used to measure clearance of locally applied dopamine (da) in rat brain slices containing the substantia nigra (sn) or striatum. |
1998-12-07 |
2023-08-12 |
rat |
| K K Yung, Y C Tse, Z G Gao, S Y Choi, F S Kwo. Localization of GABA transaminase immunoreactivity in the rat substantia nigra pars reticulata. Neuroscience letters. vol 253. issue 1. 1998-12-02. PMID:9754804. |
precise cellular localization of gamma-aminobutyric acid transaminase (gaba(t)), a degrading enzyme for the neurotransmitter gaba, was determined in the rat substantia nigra (sn) by immunocytochemical experiments using a recently developed monoclonal antibody. |
1998-12-02 |
2023-08-12 |
rat |
| M Kohutnicka, E Lewandowska, I Kurkowska-Jastrzebska, A Członkowski, A Członkowsk. Microglial and astrocytic involvement in a murine model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Immunopharmacology. vol 39. issue 3. 1998-12-01. PMID:9754903. |
a transient microglial reaction was demonstrated from the 1st until the 14th day in the substantia nigra (sn) and striatum. |
1998-12-01 |
2023-08-12 |
mouse |
| I T Demchenko, A E Boso, M J Natoli, P O Doar, T J O'Neill, P B Bennett, C A Piantados. Measurement of cerebral blood flow in rats and mice by hydrogen clearance during hyperbaric oxygen exposure. Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc. vol 25. issue 3. 1998-11-02. PMID:9789333. |
polarographic platinum electrodes 0.1 mm in diameter were used to record h2 clearance curves from the parietal cortex (pc), substantia nigra (sn), and caudate putamen nucleus (cpn) after inhalation of 2.5% h2 in air. |
1998-11-02 |
2023-08-12 |
mouse |
| A M Lin, C H Yang, C Y Cha. Striatal dopamine dynamics are altered following an intranigral infusion of iron in adult rats. Free radical biology & medicine. vol 24. issue 6. 1998-10-30. PMID:9607609. |
seven days after an intranigral infusion of iron, oxidative stress was confirmed by an elevated lipid peroxidation in lesioned substantia nigra (sn). |
1998-10-30 |
2023-08-12 |
rat |
| K Thorré, S Sarre, I Smolders, G Ebinger, Y Michott. Dopaminergic regulation of serotonin release in the substantia nigra of the freely moving rat using microdialysis. Brain research. vol 796. issue 1-2. 1998-10-29. PMID:9689460. |
the functional regulation by dopamine (da) receptors of serotonin (5-ht) release from the rat substantia nigra (sn) was investigated using in vivo microdialysis. |
1998-10-29 |
2023-08-12 |
rat |
| K Thorré, G Ebinger, Y Michott. 5-HT4 receptor involvement in the serotonin-enhanced dopamine efflux from the substantia nigra of the freely moving rat: a microdialysis study. Brain research. vol 796. issue 1-2. 1998-10-29. PMID:9689461. |
the functional regulation by serotonin (5-ht) receptors of the 5-ht-enhanced dopamine (da) release from the rat substantia nigra (sn) was investigated using in vivo microdialysis. |
1998-10-29 |
2023-08-12 |
rat |
| G L Willis, S M Armstron. Orphan neurones and amine excess: the functional neuropathology of Parkinsonism and neuropsychiatric disease. Brain research. Brain research reviews. vol 27. issue 3. 1998-10-22. PMID:9729369. |
in section 3 it is suggested that parkinsonism is due to a da excess far from the striatum in the area of the posterior lateral hypothalamus (plh) and the substantia nigra (sn). |
1998-10-22 |
2023-08-12 |
human |
| S Mohanty, H W Steinbusch, D K Ganguly, K P Mohanakuma. Behavioral and neurochemical alterations following intracerebroventricular administration of anti-serotonin antibodies in adult Balb/c mice. Journal of chemical neuroanatomy. vol 14. issue 3-4. 1998-10-20. PMID:9704892. |
5-ht and da in the nucleus raphe dorsalis (nrd), substantia nigra (sn), nucleus caudatus putamen (ncp) and in the substantia grisea centralis, and ne in the former two nuclei were significantly decreased in these animals. |
1998-10-20 |
2023-08-12 |
mouse |
| S Erhardt, B Andersson, H Nissbrandt, G Engber. Inhibition of firing rate and changes in the firing pattern of nigral dopamine neurons by gamma-hydroxybutyric acid (GHBA) are specifically induced by activation of GABA(B) receptors. Naunyn-Schmiedeberg's archives of pharmacology. vol 357. issue 6. 1998-10-16. PMID:9686936. |
previous studies have shown that administration of gamma-hydroxybutyric acid (ghba) or the gaba(b) receptor agonist baclofen are associated with a decrease in firing rate, a regularisation of firing pattern and a decrease in burst activity of midbrain dopamine (da) neurons in the substantia nigra (sn). |
1998-10-16 |
2023-08-12 |
rat |
| T Nakagomi, H Kanemitsu, K Narita, H Nakayama, T Ishii, A Tamur. Enhanced protein synthesis in the ipsilateral substantia nigra following middle cerebral artery occlusion in the rat. Acta neuropathologica. vol 95. issue 6. 1998-10-15. PMID:9650747. |
following focal cerebral ischemia, neuronal cell death is detected in remote areas of the brain, including the ipsilateral thalamus and substantia nigra (sn), as well as in the ischemic core. |
1998-10-15 |
2023-08-12 |
rat |
| Y S Kim, W S Joo, B K Jin, Y H Cho, H H Baik, C W Par. Melatonin protects 6-OHDA-induced neuronal death of nigrostriatal dopaminergic system. Neuroreport. vol 9. issue 10. 1998-10-14. PMID:9694233. |
analysis by tyrosine hydroxylase (th) immunocytochemistry revealed the loss of cell bodies in the substantia nigra (sn) and absence of terminals in the dorsolateral striatum ipsilaterally. |
1998-10-14 |
2023-08-12 |
rat |
| D Kirik, C Rosenblad, A Björklun. Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat. Experimental neurology. vol 152. issue 2. 1998-09-24. PMID:9710526. |
the results show that a 60-70% reduction in tyrosine hydroxylase (th)-positive fiber density in the lateral striatum, accompanied by a 50-60% reduction in th-positive cells in substantia nigra (sn), is sufficient for the induction of significant impairment in initiation of stepping. |
1998-09-24 |
2023-08-12 |
rat |
| S M Williams, P S Goldman-Raki. Widespread origin of the primate mesofrontal dopamine system. Cerebral cortex (New York, N.Y. : 1991). vol 8. issue 4. 1998-09-11. PMID:9651129. |
da afferents innervating the macaque frontal cortex as a whole originate from an unexpectedly widespread continuum of neurons distributed in the dorsal aspects of all three of the mesencephalic da cell groups [a9, a10 and a8; generally corresponding to the da cells of the substantia nigra (sn), vta, and the retrorubral area (rra) respectively]. |
1998-09-11 |
2023-08-12 |
monkey |
| D G Walker, K Terai, A Matsuo, T G Beach, E G McGeer, P L McGee. Immunohistochemical analyses of fibroblast growth factor receptor-1 in the human substantia nigra. Comparison between normal and Parkinson's disease cases. Brain research. vol 794. issue 2. 1998-08-27. PMID:9622624. |
the use of neurotrophic growth factors as a means of preventing loss of the dopaminergic (da) neurons in the substantia nigra (sn) is becoming an accepted treatment strategy for parkinson's disease (pd). |
1998-08-27 |
2023-08-12 |
human |