| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Offen, I Ziv, A Barzilai, S Gorodin, E Glater, A Hochman, E Melame. Dopamine-melanin induces apoptosis in PC12 cells; possible implications for the etiology of Parkinson's disease. Neurochemistry international. vol 31. issue 2. 1997-09-02. PMID:9220453. |
the function of neuromelanin (nm), the oxidized dopamine (da) polymer, within the da-producing cells in the human and primate substantia nigra (sn), is still an enigma. |
1997-09-02 |
2023-08-12 |
human |
| A Capozzo, T Florio, S Di Loreto, D Adorno, E Scarnat. Transplantation of mesencephalic cell suspension in dopamine-denervated striatum of the rat. II. Effects on corticostriatal transmission. Experimental neurology. vol 146. issue 1. 1997-08-07. PMID:9225747. |
the present study has been designed to investigate whether intrastriatal implantation of mesencephalic dopamine (da)-synthetizing neurons into the striatum (st) of rats whose substantia nigra (sn) was previously destroyed by 6-hydroxydopamine (6-ohda) restores the pattern of corticostriatal transmission from the medial prelimbic and sensorimotor cortices. |
1997-08-07 |
2023-08-12 |
rat |
| J Balthazart, P Absi. Identification of catecholaminergic inputs to and outputs from aromatase-containing brain areas of the Japanese quail by tract tracing combined with tyrosine hydroxylase immunocytochemistry. The Journal of comparative neurology. vol 382. issue 3. 1997-07-30. PMID:9183702. |
in these last two regions, many retrogradely labeled cells were located in dopaminergic areas such as the retroruberal field (rrf), substantia nigra (sn), and area ventralis of tsai (avt) but also in noradrenergic cell groups such as the locus ceruleus and subceruleus. |
1997-07-30 |
2023-08-12 |
Not clear |
| B Hontanilla, A Parent, J M Giménez-Amay. Parvalbumin and calbindin D-28k in the entopeduncular nucleus, subthalamic nucleus, and substantia nigra of the rat as revealed by double-immunohistochemical methods. Synapse (New York, N.Y.). vol 25. issue 4. 1997-07-24. PMID:9097395. |
the cellular localization of calbindin d-28k (cb) and parvalbumin (pv) was analyzed by means of double-immunohistochemical techniques applied to single sections in the entopeduncular nucleus (ep), the subthalamic nucleus (sth), and the substantia nigra (sn) of the rat. |
1997-07-24 |
2023-08-12 |
rat |
| Y Kawaguch. Neostriatal cell subtypes and their functional roles. Neuroscience research. vol 27. issue 1. 1997-07-21. PMID:9089693. |
the neostriatum is considered to be involved in the induction of purposeful movements or in the suppression of other movements through the internal segment of the globus pallidus (gp; the entopeduncular nucleus in the rodents) and the substantia nigra (sn) to which the striatal spiny neurons project. |
1997-07-21 |
2023-08-12 |
Not clear |
| P S Mohankumar, S M Mohankumar, S K Quadri, J L Voog. Chronic hyperprolactinemia and changes in dopamine neurons. Brain research bulletin. vol 42. issue 6. 1997-07-18. PMID:9128918. |
there was no change in the levels of da, norepinephrine (ne), serotonin (5-ht), or their metabolites in the arcuate nucleus (an), medial preoptic area (mpa), caudate putamen (cp), substantia nigra (sn), and zona incerta (zi), except for a decrease in 5-hydroxyindoleacetic acid (5-hiaa) in the an after 6-months of hyperprolactinemia and an increase in da concentrations in the an after 9-months of hyperprolactinemia. |
1997-07-18 |
2023-08-12 |
rat |
| C Thiffault, L Lamarre-Théroux, R Quirion, J Poirie. L-Deprenyl and MDL72974 do not improve the recovery of dopaminergic cells following systemic administration of MPTP in mouse. Brain research. Molecular brain research. vol 44. issue 2. 1997-07-08. PMID:9073165. |
in addition, l-deprenyl, administered 72 h following mptp, improves the recovery of tyrosine hydroxylase (th) immunopositive neurons in the substantia nigra (sn) of mice. |
1997-07-08 |
2023-08-12 |
mouse |
| G Engberg, A Elverfors, J Jonason, H Nissbrand. Inhibition of dopamine re-uptake: significance for nigral dopamine neuron activity. Synapse (New York, N.Y.). vol 25. issue 2. 1997-07-07. PMID:9021902. |
in the present study the effect of inhibition of the re-uptake of dopamine (da) was analysed with respect to da release and to the firing pattern of da neurons in the substantia nigra (sn). |
1997-07-07 |
2023-08-12 |
Not clear |
| N E Saadé, S F Atweh, N B Bahuth, S J Jabbu. Augmentation of nociceptive reflexes and chronic deafferentation pain by chemical lesions of either dopaminergic terminals or midbrain dopaminergic neurons. Brain research. vol 751. issue 1. 1997-06-09. PMID:9098562. |
using various pain tests for acute (hot plate test, hpt, tail flick, tft, paw pressure test, ppt and paw immersion test, pit) and chronic deafferentation (autotomy, at, following peripheral neurectomy) pains in rats, we have investigated the effects on these tests of selective chemical lesions with 6-hydroxydopamine (6-ohda) or/and kainic acid (ka) either in the striatum or in the substantia nigra (sn) and ventral tegmental area (vta). |
1997-06-09 |
2023-08-12 |
rat |
| T Verina, J A Norton, J J Sorbel, L C Triarhou, D Laferty, J A Richter, J R Simon, B Ghett. Atrophy and loss of dopaminergic mesencephalic neurons in heterozygous weaver mice. Experimental brain research. vol 113. issue 1. 1997-05-29. PMID:9028770. |
we counted tyrosine hydroxylase (th)-immunopositive cells in the substantia nigra (sn), retrorubral nucleus (rrn), and ventral tegmental area (vta), and measured cross-sectional areas of neuronal somata in the sn of wv/+ and age-matched wild-type controls (+/+). |
1997-05-29 |
2023-08-12 |
mouse |
| T F Oo, R E Burk. The time course of developmental cell death in phenotypically defined dopaminergic neurons of the substantia nigra. Brain research. Developmental brain research. vol 98. issue 2. 1997-05-27. PMID:9051260. |
we have previously shown that apoptotic natural cell death occurs within the substantia nigra (sn) pars compacta of the rat postnatally. |
1997-05-27 |
2023-08-12 |
rat |
| F Wat. Nuclear microscope analysis in Alzheimer's and Parkinson's disease: A review. Cellular and molecular biology (Noisy-le-Grand, France). vol 42. issue 1. 1997-05-23. PMID:8833663. |
in parkinson's disease (pd) nuclear microscope studies have concentrated on measurements of iron in the substantia nigra (sn) region of the brain; iron was observed to be elevated by a factor 2 in mptp induced parkinsonism in african green monkeys, and by a factor of 1.25 in 6-ohda induced parkinsonism in sprague dawley rats. |
1997-05-23 |
2023-08-12 |
rat |
| M F Kritze. Selective colocalization of immunoreactivity for intracellular gonadal hormone receptors and tyrosine hydroxylase in the ventral tegmental area, substantia nigra, and retrorubral fields in the rat. The Journal of comparative neurology. vol 379. issue 2. 1997-05-21. PMID:9050788. |
to identify which midbrain cells may be targets of genomic influence, double label immunocytochemistry was used to map intracellular estrogen and androgen receptors and tyrosine hydroxylase (th) in the ventral tegmental area (vta), substantia nigra (sn), and retrorubral fields (rrf) in intact, adult rats. |
1997-05-21 |
2023-08-12 |
rat |
| A A Dunn-Meynell, V H Routh, J J McArdle, B E Levi. Low-affinity sulfonylurea binding sites reside on neuronal cell bodies in the brain. Brain research. vol 745. issue 1-2. 1997-04-29. PMID:9037388. |
high-affinity sulfonylurea binding sites are concentrated in areas such as the substantia nigra (sn) where glucose and sulfonylureas increase transmitter release from gaba neurons. |
1997-04-29 |
2023-08-12 |
Not clear |
| W J Kelly, R E Burk. Apoptotic neuron death in rat substantia nigra induced by striatal excitotoxic injury is developmentally dependent. Neuroscience letters. vol 220. issue 2. 1997-03-20. PMID:8981479. |
we have previously observed that an axon-sparing lesion of the striatum during development is associated with an induction of apoptotic cell death in the substantia nigra (sn). |
1997-03-20 |
2023-08-12 |
rat |
| M Poltorak, J R Williams, K D Moore, W J Free. Changes in L1 antigen expression in the rat striatum after substantia nigra lesions. Journal of neural transplantation & plasticity. vol 6. issue 1. 1997-03-19. PMID:8959552. |
in the medial-periventricular part of the striatum, both complete and partial substantia nigra (sn) lesions decreased l1 expression. |
1997-03-19 |
2023-08-12 |
rat |
| S S Shim, B S Bunney, W X Sh. Effects of lesions in the medial prefrontal cortex on the activity of midbrain dopamine neurons. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 15. issue 5. 1997-03-14. PMID:8914116. |
in the substantia nigra (sn), the same lesions increased the firing rate and had no effect on either the bursting activity of the number of active da cells. |
1997-03-14 |
2023-08-12 |
rat |
| A Roll, M M Wierzbicka, W Wol. The "gap paradigm" leads to express-like saccadic reaction times in Parkinson's disease. Experimental brain research. vol 111. issue 1. 1997-03-11. PMID:8891643. |
it was suggested that the substantia nigra (sn) could take part in the control of these saccades. |
1997-03-11 |
2023-08-12 |
human |
| J Nabekura, T Omura, N Akaik. Alpha 2 adrenoceptor potentiates glycine receptor-mediated taurine response through protein kinase A in rat substantia nigra neurons. Journal of neurophysiology. vol 76. issue 4. 1997-03-11. PMID:8899617. |
the modulatory effect of alpha 2 adrenoceptor on the taurine response was investigated in substantia nigra (sn) neurons acutely dissociated from the rat using a nystatin perforated-patch recording mode under voltage-clamp conditions. |
1997-03-11 |
2023-08-12 |
rat |
| J Nabekura, T Omura, N Horimoto, T Ogawa, N Akaik. Alpha 1 adrenoceptor activation potentiates taurine response mediated by protein kinase C in substantia nigra neurons. Journal of neurophysiology. vol 76. issue 4. 1997-03-11. PMID:8899618. |
the potentiation of glycine receptor-mediated taurine response (itau) by alpha 1 adrenoceptor activation was investigated in neurons freshly dissociated from the rat substantia nigra (sn) using a nystatin perforated-patch recording. |
1997-03-11 |
2023-08-12 |
rat |