| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I S Lolova, S R Lolo. Age-related changes in basic fibroblast growth factor-immunoreactive cells of rat substantia nigra. Mechanisms of ageing and development. vol 82. issue 2-3. 1996-02-08. PMID:8538246. |
immunohistochemistry and computer-assisted image analysis were used to examine the age-related changes in bfgf-immunoreactivity in rat substantia nigra (sn). |
1996-02-08 |
2023-08-12 |
rat |
| B Ziolkowska, G Horn, A Kupsch, V Höll. The expression of proenkephalin and prodynorphin genes and the induction of c-fos gene by dopaminergic drugs are not altered in the straitum of MPTP-treated mice. Journal of neural transmission. Parkinson's disease and dementia section. vol 9. issue 2-3. 1996-02-01. PMID:8527000. |
two weeks after systemic administration of mptp (2 x 40 mg/kg, s.c. 18h apart), the lesion of the substantia nigra (sn) could be visualised by loss of the nigral tyrosine hydroxylase (th) mrna hybridization signal and by a 91% decrease in striatal dopamine levels. |
1996-02-01 |
2023-08-12 |
mouse |
| J F O'Callaghan, S A Greenfiel. Inhibition of the ATP-sensitive potassium channel in the guinea pig substantia nigra by BMS 181100 is not mediated by a sigma-binding site. Journal of neuroscience research. vol 42. issue 1. 1996-01-30. PMID:8531229. |
quantitative autoradiography of brain tissue has revealed a high density of binding sites for the k-atp channel antagonists, the sulphonylureas, and for sigma-ligands in the substantia nigra (sn). |
1996-01-30 |
2023-08-12 |
Not clear |
| H Okamura, C Yokoyama, Y Ibat. Lateromedial gradient of the susceptibility of midbrain dopaminergic neurons to neonatal 6-hydroxydopamine toxicity. Experimental neurology. vol 136. issue 2. 1996-01-17. PMID:7498403. |
in all cases of intracisternal 6-ohda treatment, a9 dopaminergic neurons in the substantia nigra (sn) were much more vulnerable to death than more medially located a10 dopaminergic neurons. |
1996-01-17 |
2023-08-12 |
Not clear |
| O K Ronnekleiv, B R Naylo. Chronic cocaine exposure in the fetal rhesus monkey: consequences for early development of dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 11. 1995-12-26. PMID:7472487. |
also in the day 60 fetuses, the th-ir neurons were distributed similarly in both groups (n = 5 each), but the th mrna content, measured by quantitative in situ hybridization, was reduced in the substantia nigra (sn) and ventral tegmental area (vta) after cocaine treatment. |
1995-12-26 |
2023-08-12 |
monkey |
| T Yamad. Further observations on MxA-positive Lewy bodies in Parkinson's disease brain tissues. Neuroscience letters. vol 195. issue 1. 1995-12-18. PMID:7478250. |
we recently reported that in cases of parkinson's disease (pd), lewy bodies (lbs) in the substantia nigra (sn) were positive for mxa. |
1995-12-18 |
2023-08-12 |
mouse |
| C Thiffault, N Aumont, R Quirion, J Poirie. Effect of MPTP and L-deprenyl on antioxidant enzymes and lipid peroxidation levels in mouse brain. Journal of neurochemistry. vol 65. issue 6. 1995-12-15. PMID:7595571. |
at the level of the substantia nigra (sn), even though increases in cat activity and reduction in sod and gsh-px activities were detected, lipid peroxidation was not altered. |
1995-12-15 |
2023-08-12 |
mouse |
| A Jaffer, G D van der Spuy, V A Russell, M Mintz, J J Taljaar. Activation of the subthalamic nucleus and pedunculopontine tegmentum: does it affect dopamine levels in the substantia nigra, nucleus accumbens and striatum? Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration. vol 4. issue 2. 1995-11-28. PMID:7583677. |
this study investigated whether death of substantia nigra (sn) dopaminergic neurons could be caused by the hyperactivity of afferent pathways resulting in the release of a toxic dose of excitatory amino acids in the sn. |
1995-11-28 |
2023-08-12 |
rat |
| M C Doretto, N Garcia-Cairasc. Differential audiogenic seizure sensitization by selective unilateral substantia nigra lesions in resistant Wistar rats. Physiology & behavior. vol 58. issue 2. 1995-11-03. PMID:7568430. |
evaluation of the participation of different substantia nigra sites in the sensitization of resistant (r) animals to audiogenic seizures (as), was performed after series of small (5 mc; n = 28), medium (10 mc; n = 57) and large (15 mc; 3 points of 5 mc each, n = 19) unilateral electrolytic lesions of the substantia nigra (sn) in r rats. |
1995-11-03 |
2023-08-12 |
rat |
| C A Kitt, B J Wilco. Preliminary evidence for neurodegenerative changes in the substantia nigra of Rett syndrome. Neuropediatrics. vol 26. issue 2. 1995-10-30. PMID:7566448. |
the results of our preliminary studies show abnormalities in neurons of the substantia nigra (sn), including decreased numbers of neurons, ubiquitin-stained neuronal inclusion bodies, decreased immunostaining for transmitter markers, and evidence of cell death using terminal deoxynucleotidyl transferase (tdt)-mediated dutp-biotin nick end labeling (tunel), which labels fragmented intranucleosomal dna. |
1995-10-30 |
2023-08-12 |
Not clear |
| H Ito, H Kusaka, S Matsumoto, T Ima. Topographic involvement of the striatal efferents in basal ganglia of patients with adult-onset motor neuron disease with basophilic inclusions. Acta neuropathologica. vol 89. issue 6. 1995-10-17. PMID:7545858. |
this report concerns the topographic immunohistochemical analysis of the putamen, globus pallidus (gp) and substantia nigra (sn) of two patients with adult-onset motor neuron disease with basophilic inclusions (mnd/bis), seven patients with sporadic classic amyotrophic lateral sclerosis (sporadic als) and five neurologically normal individuals. |
1995-10-17 |
2023-08-12 |
human |
| S A Oakman, P L Faris, P E Kerr, C Cozzari, B K Hartma. Distribution of pontomesencephalic cholinergic neurons projecting to substantia nigra differs significantly from those projecting to ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 9. 1995-10-12. PMID:7666171. |
stereotaxic microinjections of fluoro-gold- or rhodamine-labeled microspheres were made either to substantia nigra (sn) or ventral tegmental area (vta) in rat. |
1995-10-12 |
2023-08-12 |
rat |
| A M Kazee, C Cox, E K Richfiel. Substantia nigra lesions in Alzheimer disease and normal aging. Alzheimer disease and associated disorders. vol 9. issue 2. 1995-10-10. PMID:7662324. |
we retrospectively examined clinical and neuropathological features from 66 individuals participating in the rochester alzheimer disease center to determine the association of ad with substantia nigra (sn) pathology. |
1995-10-10 |
2023-08-12 |
Not clear |
| J Röper, F M Ashcrof. Metabolic inhibition and low internal ATP activate K-ATP channels in rat dopaminergic substantia nigra neurones. Pflugers Archiv : European journal of physiology. vol 430. issue 1. 1995-10-10. PMID:7667078. |
the patch-clamp technique was used to study whole-cell currents of acutely dissociated rat substantia nigra (sn) neurones. |
1995-10-10 |
2023-08-12 |
rat |
| K Korematsu, S Goto, S Nagahiro, N Inoue, T Oyama, K Yamada, Y Ushi. Change of phosphotyrosine immunoreactivity on microglia in the rat substantia nigra following striatal ischemic injury. Glia. vol 13. issue 2. 1995-09-28. PMID:7544325. |
using immunohistochemistry, we investigated changes in phosphotyrosine (p-tyr) immunoreactivity on the microglia of the rat substantia nigra (sn) following striatal ischemic injury produced by transient middle cerebral artery (mca) occlusion. |
1995-09-28 |
2023-08-12 |
rat |
| D G Davis, D L Spark. Dopaminergic and serotonergic neurotransmitters in bone marrow transplant patients. Journal of the neurological sciences. vol 130. issue 1. 1995-09-26. PMID:7544403. |
depigmentation of neurons in the substantia nigra (sn) is found in patients dying after bone marrow transplantation (bmt). |
1995-09-26 |
2023-08-12 |
human |
| T Himi, M Cao, N Mor. Reduced expression of the molecular markers of dopaminergic neuronal atrophy in the aging rat brain. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 50. issue 4. 1995-08-18. PMID:7614230. |
expression of mrnas encoding the dopamine transporter (dat) and tyrosine hydroxylase (th) in dopaminergic neurons of the substantia nigra (sn) was examined in young and aged fischer 344 rats by in situ hybridization. |
1995-08-18 |
2023-08-12 |
rat |
| S Fenu, A Carta, M Morell. Modulation of dopamine D1-mediated turning behavior and striatal c-fos expression by the substantia nigra. Synapse (New York, N.Y.). vol 19. issue 4. 1995-07-26. PMID:7792718. |
in order to study the possible contribution of the substantia nigra (sn) in the positive interaction between dopamine d1 receptor agonists and glutamate antagonists in unilaterally 6-hydroxydopamine (6-ohda) lesioned rats, the effect of the d1 agonist, skf 38393, was studied in combination with intranigral infusions of glutamate antagonists of the nmda (mk 801, cpp) or ampa (nbqx) type of receptor. |
1995-07-26 |
2023-08-12 |
rat |
| D L Rosin, K Melia, A M Knorr, E J Nestler, R H Roth, R S Duma. Chronic imipramine administration alters the activity and phosphorylation state of tyrosine hydroxylase in dopaminergic regions of rat brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 12. issue 2. 1995-07-20. PMID:7779239. |
chronic administration of imipramine (18 days) decreased levels of th enzyme activity in ventral tegmental area (vta) and substantia nigra (sn), dopaminergic cell body regions, as well as in caudate-putamen (cp), nucleus accumbens (acb), prefrontal cortex (pfc), and olfactory tubercle (ot), dopaminergic terminal fields. |
1995-07-20 |
2023-08-12 |
rat |
| J Abarca, K Gysling, R H Roth, G Busto. Changes in extracellular levels of glutamate and aspartate in rat substantia nigra induced by dopamine receptor ligands: in vivo microdialysis studies. Neurochemical research. vol 20. issue 2. 1995-07-20. PMID:7783840. |
the microdialysis technique was utilized to study the local effects of d1 and d2 family type dopamine (da) receptor (r) ligands on the in vivo release of endogenous glutamate (glu) and aspartate (asp) from rat substantia nigra (sn). |
1995-07-20 |
2023-08-12 |
rat |